AU562056B2 - 1,3-dioxan-5-ylalkenoic acids - Google Patents

1,3-dioxan-5-ylalkenoic acids

Info

Publication number
AU562056B2
AU562056B2 AU14223/83A AU1422383A AU562056B2 AU 562056 B2 AU562056 B2 AU 562056B2 AU 14223/83 A AU14223/83 A AU 14223/83A AU 1422383 A AU1422383 A AU 1422383A AU 562056 B2 AU562056 B2 AU 562056B2
Authority
AU
Australia
Prior art keywords
phenyl
formula
hydroxy
methyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU14223/83A
Other languages
English (en)
Other versions
AU1422383A (en
Inventor
Andrew George Brewster
Peter William Rodney Caulkett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of AU1422383A publication Critical patent/AU1422383A/en
Application granted granted Critical
Publication of AU562056B2 publication Critical patent/AU562056B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU14223/83A 1982-05-12 1983-05-04 1,3-dioxan-5-ylalkenoic acids Ceased AU562056B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8213702 1982-05-12
GB8213702 1982-05-12

Publications (2)

Publication Number Publication Date
AU1422383A AU1422383A (en) 1983-11-17
AU562056B2 true AU562056B2 (en) 1987-05-28

Family

ID=10530304

Family Applications (1)

Application Number Title Priority Date Filing Date
AU14223/83A Ceased AU562056B2 (en) 1982-05-12 1983-05-04 1,3-dioxan-5-ylalkenoic acids

Country Status (32)

Country Link
US (3) US4567197A (enExample)
EP (1) EP0094239B1 (enExample)
JP (1) JPS58222081A (enExample)
KR (1) KR880002001B1 (enExample)
AR (1) AR240817A1 (enExample)
AT (1) ATE28329T1 (enExample)
AU (1) AU562056B2 (enExample)
CA (4) CA1258464A (enExample)
CS (2) CS245795B2 (enExample)
CY (1) CY1453A (enExample)
DD (2) DD219769A5 (enExample)
DE (1) DE3372483D1 (enExample)
DK (1) DK163431C (enExample)
ES (4) ES522331A0 (enExample)
FI (1) FI80027C (enExample)
GB (1) GB8310407D0 (enExample)
GR (1) GR78138B (enExample)
HK (1) HK17889A (enExample)
HU (1) HU198705B (enExample)
IE (1) IE55114B1 (enExample)
IL (1) IL68628A0 (enExample)
KE (1) KE3823A (enExample)
MW (1) MW1583A1 (enExample)
NO (1) NO162383B (enExample)
NZ (1) NZ204202A (enExample)
PH (1) PH21691A (enExample)
PL (3) PL140462B1 (enExample)
PT (1) PT76684B (enExample)
SG (1) SG57088G (enExample)
SU (1) SU1277893A3 (enExample)
ZA (1) ZA833179B (enExample)
ZW (1) ZW10083A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582438B2 (en) * 1985-05-10 1989-03-23 Imperial Chemical Industries Plc 1,3-dioxane ethers
AU583375B2 (en) * 1985-05-10 1989-04-27 Imperial Chemical Industries Plc 2,4-diphenyl-1,3-dioxanes
AU587962B2 (en) * 1983-11-11 1989-09-07 Imperial Chemical Industries Plc Process for the manufacture of erythro-dihydroxyalkenoic acid derivatives
AU617172B2 (en) * 1983-08-31 1991-11-21 Imperial Chemical Industries Plc Process for making 1,3-dioxane derivatives

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
GB8330097D0 (en) * 1983-11-11 1983-12-21 Ici Plc Cyclic ethers
GB8330094D0 (en) * 1983-11-11 1983-12-21 Ici Plc Diphenyl compounds
GB8417314D0 (en) * 1984-07-06 1984-08-08 Ici Plc Carboxylic acid derivatives
GR861209B (en) * 1985-05-10 1986-08-29 Ici Plc Process for preparing novel alkene derivatives
GB8511892D0 (en) * 1985-05-10 1985-06-19 Ici Plc Fluoralkane derivatives
GB8511894D0 (en) 1985-05-10 1985-06-19 Ici Plc Phenol derivatives
GB8511891D0 (en) * 1985-05-10 1985-06-19 Ici Plc Alkenoic acids
GB8511895D0 (en) * 1985-05-10 1985-06-19 Ici Plc Heterocyclic compounds
GB8511897D0 (en) * 1985-05-10 1985-06-19 Ici Plc Carboxylic acids
ES2017633B3 (es) * 1985-11-12 1991-03-01 Ici Plc Amido derivados.
GB8611174D0 (en) * 1986-05-08 1986-06-18 Ici Plc Amide derivatives
GB8531892D0 (en) * 1985-12-30 1986-02-05 Ici Plc Carboxylic acids
DE3603662A1 (de) * 1986-02-06 1987-08-13 Basf Ag Acetalisierte oder ketalisierte dihydroxyaldehyde, verfahren zu ihrer herstellung und diese enthaltende loesungen
GB8626297D0 (en) * 1986-11-04 1986-12-03 Ici Plc Pharmaceutical compositions
GB8626296D0 (en) * 1986-11-04 1986-12-03 Ici Plc Therapeutic agents
GB8709794D0 (en) * 1987-04-24 1987-05-28 Ici Plc Heterocyclic acids
GB8901201D0 (en) * 1988-02-16 1989-03-15 Ici Plc Pyridine derivatives
US5248780A (en) * 1988-02-16 1993-09-28 Imperial Chemical Industries, Plc Pyridyl substituted alkenoic acid derivatives
EP0346511A1 (en) * 1988-06-15 1989-12-20 Fujisawa Pharmaceutical Co., Ltd. Oxygen-containing hererocyclic compound, processes for their preparation and pharmaceutical compositions comprising them
CN1034120C (zh) * 1988-10-21 1997-02-26 曾尼卡有限公司 制备二噁烷链烯酸衍生物的方法
IE81170B1 (en) * 1988-10-21 2000-05-31 Zeneca Ltd Pyridine derivatives
GB9021571D0 (en) * 1990-10-04 1990-11-21 Ici Plc Heterocyclic acids
US5925795A (en) * 1996-09-16 1999-07-20 Zeneca Limited Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates
GB0413970D0 (en) * 2004-06-22 2004-07-28 Syngenta Participations Ag Chemical compounds
US20110178112A1 (en) * 2006-01-18 2011-07-21 Evolva Sa PPAR Modulators
MX2009007667A (es) * 2007-01-18 2011-12-08 Evolva Sa Profarmacos de 1,3-dioxanos sustituidos y sus usos.
EP2150111B1 (en) 2007-01-18 2016-10-19 Evolva SA Substituted 1,3-dioxanes useful as ppar modulators
CA2871545A1 (en) * 2012-05-18 2013-11-21 Sanofi Benzo[1,3]dioxine derivatives and their use as lpar5 antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4243592A (en) * 1979-03-12 1981-01-06 The Upjohn Company 9,11-Dideoxy-10-oxa-TXB compounds
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
GB8417314D0 (en) * 1984-07-06 1984-08-08 Ici Plc Carboxylic acid derivatives

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU617172B2 (en) * 1983-08-31 1991-11-21 Imperial Chemical Industries Plc Process for making 1,3-dioxane derivatives
AU587962B2 (en) * 1983-11-11 1989-09-07 Imperial Chemical Industries Plc Process for the manufacture of erythro-dihydroxyalkenoic acid derivatives
AU582438B2 (en) * 1985-05-10 1989-03-23 Imperial Chemical Industries Plc 1,3-dioxane ethers
AU583375B2 (en) * 1985-05-10 1989-04-27 Imperial Chemical Industries Plc 2,4-diphenyl-1,3-dioxanes

Also Published As

Publication number Publication date
ES8407038A1 (es) 1984-08-16
US5166377A (en) 1992-11-24
CS725784A2 (en) 1985-09-17
SG57088G (en) 1989-01-27
GB8310407D0 (en) 1983-05-25
ES522331A0 (es) 1984-08-16
IE55114B1 (en) 1990-06-06
NO162383B (no) 1989-09-11
FI831664A0 (fi) 1983-05-12
ZW10083A1 (en) 1984-11-28
PL140462B1 (en) 1987-04-30
PL140463B1 (en) 1987-04-30
CY1453A (en) 1989-07-21
KR880002001B1 (ko) 1988-10-11
ES528575A0 (es) 1986-10-16
EP0094239A2 (en) 1983-11-16
AR240817A2 (es) 1991-02-28
CS333683A2 (en) 1985-09-17
ES8700250A1 (es) 1986-10-16
EP0094239B1 (en) 1987-07-15
PL140274B1 (en) 1987-04-30
PL241920A1 (en) 1985-03-26
FI80027C (fi) 1990-04-10
ES8700249A1 (es) 1986-10-16
GR78138B (enExample) 1984-09-26
IL68628A0 (en) 1984-05-31
CA1268771C (enExample) 1990-05-08
KE3823A (en) 1988-10-21
NO831679L (no) 1983-11-14
FI831664L (fi) 1983-11-13
DK163431C (da) 1992-07-20
IE831005L (en) 1983-11-12
PH21691A (en) 1988-01-13
CS245795B2 (en) 1986-10-16
DE3372483D1 (de) 1987-08-20
PT76684B (en) 1986-01-14
PL250098A1 (en) 1985-07-02
ATE28329T1 (de) 1987-08-15
US4745198A (en) 1988-05-17
HK17889A (en) 1989-03-10
ES8608507A1 (es) 1986-06-16
JPH0378389B2 (enExample) 1991-12-13
CA1268772A (en) 1990-05-08
CS245783B2 (en) 1986-10-16
NZ204202A (en) 1986-05-09
CA1268771A (en) 1990-05-08
US4567197A (en) 1986-01-28
SU1277893A3 (ru) 1986-12-15
PL250099A1 (en) 1985-07-02
EP0094239A3 (en) 1984-12-12
MW1583A1 (en) 1985-02-13
DK211883A (da) 1983-11-13
CA1258464A (en) 1989-08-15
PT76684A (en) 1983-06-01
AR240817A1 (es) 1991-02-28
ZA833179B (en) 1984-04-25
DK211883D0 (da) 1983-05-11
HU198705B (en) 1989-11-28
DD219769A5 (de) 1985-03-13
ES528577A0 (es) 1986-06-16
KR840004739A (ko) 1984-10-24
JPS58222081A (ja) 1983-12-23
CA1269109A (en) 1990-05-15
AU1422383A (en) 1983-11-17
FI80027B (fi) 1989-12-29
DD212515A5 (de) 1984-08-15
ES528576A0 (es) 1986-10-16
DK163431B (da) 1992-03-02

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