AU4946597A - Benzoxazole derivative with an affinity to binding sites of amino acid receptor - Google Patents

Benzoxazole derivative with an affinity to binding sites of amino acid receptor Download PDF

Info

Publication number
AU4946597A
AU4946597A AU49465/97A AU4946597A AU4946597A AU 4946597 A AU4946597 A AU 4946597A AU 49465/97 A AU49465/97 A AU 49465/97A AU 4946597 A AU4946597 A AU 4946597A AU 4946597 A AU4946597 A AU 4946597A
Authority
AU
Australia
Prior art keywords
formula
compound
acid
physiologically acceptable
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU49465/97A
Other languages
English (en)
Inventor
Rudolf Gottschlich
Joachim Leibrock
Helmut Prucher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU4946597A publication Critical patent/AU4946597A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU49465/97A 1996-10-30 1997-10-10 Benzoxazole derivative with an affinity to binding sites of amino acid receptor Abandoned AU4946597A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19643790 1996-10-30
DE19643790A DE19643790A1 (de) 1996-10-30 1996-10-30 Benzoxazol-Derivat
PCT/EP1997/005590 WO1998018793A1 (de) 1996-10-30 1997-10-10 Benzoxazolderivat mit affinität zu bindungsstellen von aminosäurerezeptoren

Publications (1)

Publication Number Publication Date
AU4946597A true AU4946597A (en) 1998-05-22

Family

ID=7809592

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49465/97A Abandoned AU4946597A (en) 1996-10-30 1997-10-10 Benzoxazole derivative with an affinity to binding sites of amino acid receptor

Country Status (16)

Country Link
EP (1) EP0938485A1 (pt)
JP (1) JP2001502713A (pt)
KR (1) KR20000052876A (pt)
CN (1) CN1235604A (pt)
AR (1) AR008512A1 (pt)
AU (1) AU4946597A (pt)
BR (1) BR9712577A (pt)
CA (1) CA2270359A1 (pt)
CZ (1) CZ147999A3 (pt)
DE (1) DE19643790A1 (pt)
HU (1) HUP9904547A3 (pt)
NO (1) NO992063L (pt)
PL (1) PL332771A1 (pt)
SK (1) SK53699A3 (pt)
WO (1) WO1998018793A1 (pt)
ZA (1) ZA979725B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
DE19812331A1 (de) 1998-03-20 1999-09-23 Merck Patent Gmbh Piperidinderivate
PE20000728A1 (es) 1998-06-26 2000-08-21 Cocensys Inc Heterociclos 4-bencil piperidina alquilsulfoxido y su uso como antagonistas receptores subtipo-selectivo nmda
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
EP1674087A1 (en) 2000-10-02 2006-06-28 Pfizer Products Inc. Prophylactic use of n-methyl-d-aspartate (NMDA) antagonists
DE10120159A1 (de) * 2001-04-25 2002-10-31 Merck Patent Gmbh NMDA-Antagonisten und NMDA-Agonisten zur Behandlung von Suchterkrankungen
CZ2004233A3 (cs) 2001-07-24 2004-12-15 Richter Gedeon Vegyészeti Gyár Rt. Nové amidové sloučeniny karboxylové kyseliny
DE102007047737A1 (de) * 2007-10-05 2009-04-30 Merck Patent Gmbh Piperidin- und Piperazinderivate
DE102009049211A1 (de) 2009-10-13 2011-04-28 Merck Patent Gmbh Sulfoxide
CA2851387A1 (en) 2011-11-22 2013-05-30 The Regents Of The University Of California Cysteamine and/or cystamine for treating ischemic injury

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0709384B1 (de) * 1994-10-31 1998-12-23 MERCK PATENT GmbH Benzylpiperidinderivate mit hoher Affinität zu Bindungsstellen von Aminosäure-Rezeptoren

Also Published As

Publication number Publication date
HUP9904547A3 (en) 2001-01-29
EP0938485A1 (de) 1999-09-01
AR008512A1 (es) 2000-01-19
NO992063D0 (no) 1999-04-29
PL332771A1 (en) 1999-10-11
WO1998018793A1 (de) 1998-05-07
NO992063L (no) 1999-04-29
JP2001502713A (ja) 2001-02-27
SK53699A3 (en) 2000-03-13
ZA979725B (en) 1998-05-22
KR20000052876A (ko) 2000-08-25
DE19643790A1 (de) 1998-05-07
CZ147999A3 (cs) 1999-08-11
BR9712577A (pt) 1999-10-19
HUP9904547A2 (hu) 2000-12-28
CN1235604A (zh) 1999-11-17
CA2270359A1 (en) 1998-05-07

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted