PL332771A1 - Derivatives of benzoxazoles exhibiting affinity to bonding locations of amino acid receptors - Google Patents

Derivatives of benzoxazoles exhibiting affinity to bonding locations of amino acid receptors

Info

Publication number
PL332771A1
PL332771A1 PL97332771A PL33277197A PL332771A1 PL 332771 A1 PL332771 A1 PL 332771A1 PL 97332771 A PL97332771 A PL 97332771A PL 33277197 A PL33277197 A PL 33277197A PL 332771 A1 PL332771 A1 PL 332771A1
Authority
PL
Poland
Prior art keywords
benzoxazoles
derivatives
amino acid
acid receptors
bonding locations
Prior art date
Application number
PL97332771A
Other languages
English (en)
Inventor
Helmut Pruecher
Rudolf Gottschlich
Joachim Leibrock
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL332771A1 publication Critical patent/PL332771A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL97332771A 1996-10-30 1997-10-10 Derivatives of benzoxazoles exhibiting affinity to bonding locations of amino acid receptors PL332771A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19643790A DE19643790A1 (de) 1996-10-30 1996-10-30 Benzoxazol-Derivat

Publications (1)

Publication Number Publication Date
PL332771A1 true PL332771A1 (en) 1999-10-11

Family

ID=7809592

Family Applications (1)

Application Number Title Priority Date Filing Date
PL97332771A PL332771A1 (en) 1996-10-30 1997-10-10 Derivatives of benzoxazoles exhibiting affinity to bonding locations of amino acid receptors

Country Status (16)

Country Link
EP (1) EP0938485A1 (xx)
JP (1) JP2001502713A (xx)
KR (1) KR20000052876A (xx)
CN (1) CN1235604A (xx)
AR (1) AR008512A1 (xx)
AU (1) AU4946597A (xx)
BR (1) BR9712577A (xx)
CA (1) CA2270359A1 (xx)
CZ (1) CZ147999A3 (xx)
DE (1) DE19643790A1 (xx)
HU (1) HUP9904547A3 (xx)
NO (1) NO992063L (xx)
PL (1) PL332771A1 (xx)
SK (1) SK53699A3 (xx)
WO (1) WO1998018793A1 (xx)
ZA (1) ZA979725B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
DE19812331A1 (de) * 1998-03-20 1999-09-23 Merck Patent Gmbh Piperidinderivate
PE20000728A1 (es) 1998-06-26 2000-08-21 Cocensys Inc Heterociclos 4-bencil piperidina alquilsulfoxido y su uso como antagonistas receptores subtipo-selectivo nmda
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
EP1674087A1 (en) 2000-10-02 2006-06-28 Pfizer Products Inc. Prophylactic use of n-methyl-d-aspartate (NMDA) antagonists
DE10120159A1 (de) * 2001-04-25 2002-10-31 Merck Patent Gmbh NMDA-Antagonisten und NMDA-Agonisten zur Behandlung von Suchterkrankungen
ATE408611T1 (de) 2001-07-24 2008-10-15 Richter Gedeon Nyrt Piperidine als nmda-rezeptorantagonisten
DE102007047737A1 (de) * 2007-10-05 2009-04-30 Merck Patent Gmbh Piperidin- und Piperazinderivate
DE102009049211A1 (de) 2009-10-13 2011-04-28 Merck Patent Gmbh Sulfoxide
SG11201402472QA (en) 2011-11-22 2014-06-27 Univ California Cysteamine and/or cystamine for treating ischemic injury

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE174915T1 (de) * 1994-10-31 1999-01-15 Merck Patent Gmbh Benzylpiperidinderivate mit hoher affinität zu bindungsstellen von aminosäure-rezeptoren

Also Published As

Publication number Publication date
CA2270359A1 (en) 1998-05-07
WO1998018793A1 (de) 1998-05-07
JP2001502713A (ja) 2001-02-27
HUP9904547A3 (en) 2001-01-29
NO992063D0 (no) 1999-04-29
AU4946597A (en) 1998-05-22
CZ147999A3 (cs) 1999-08-11
SK53699A3 (en) 2000-03-13
HUP9904547A2 (hu) 2000-12-28
ZA979725B (en) 1998-05-22
NO992063L (no) 1999-04-29
AR008512A1 (es) 2000-01-19
CN1235604A (zh) 1999-11-17
EP0938485A1 (de) 1999-09-01
DE19643790A1 (de) 1998-05-07
BR9712577A (pt) 1999-10-19
KR20000052876A (ko) 2000-08-25

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