AU2017290354C1 - Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile - Google Patents

Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile Download PDF

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AU2017290354C1
AU2017290354C1 AU2017290354A AU2017290354A AU2017290354C1 AU 2017290354 C1 AU2017290354 C1 AU 2017290354C1 AU 2017290354 A AU2017290354 A AU 2017290354A AU 2017290354 A AU2017290354 A AU 2017290354A AU 2017290354 C1 AU2017290354 C1 AU 2017290354C1
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dosage form
oral dosage
modified release
solid oral
compound
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AU2017290354B8 (en
AU2017290354B2 (en
AU2017290354A1 (en
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Abu J. Ferdous
Wu Lin
Mohammad R. Masjedizadeh
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Principia Biopharma Inc
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Principia Biopharma Inc
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    • A—HUMAN NECESSITIES
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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AU2017290354A 2016-06-29 2017-06-29 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile Active AU2017290354C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023201685A AU2023201685A1 (en) 2016-06-29 2023-03-17 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662356345P 2016-06-29 2016-06-29
US62/356,345 2016-06-29
PCT/US2017/040075 WO2018005849A1 (en) 2016-06-29 2017-06-29 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Related Child Applications (1)

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AU2023201685A Division AU2023201685A1 (en) 2016-06-29 2023-03-17 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Publications (4)

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AU2017290354A1 AU2017290354A1 (en) 2019-01-24
AU2017290354B2 AU2017290354B2 (en) 2022-12-22
AU2017290354B8 AU2017290354B8 (en) 2023-01-12
AU2017290354C1 true AU2017290354C1 (en) 2023-07-06

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AU2017290354A Active AU2017290354C1 (en) 2016-06-29 2017-06-29 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile
AU2023201685A Abandoned AU2023201685A1 (en) 2016-06-29 2023-03-17 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

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AU2023201685A Abandoned AU2023201685A1 (en) 2016-06-29 2023-03-17 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

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US (4) US20190231784A1 (enExample)
EP (1) EP3478273A1 (enExample)
JP (1) JP7129704B2 (enExample)
KR (2) KR102391693B1 (enExample)
CN (2) CN109600989B (enExample)
AU (2) AU2017290354C1 (enExample)
CA (1) CA3028169C (enExample)
EA (1) EA201892836A1 (enExample)
IL (2) IL293621B2 (enExample)
MA (1) MA45547A (enExample)
MX (2) MX390619B (enExample)
SG (1) SG11201811255WA (enExample)
WO (1) WO2018005849A1 (enExample)

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JP7555327B2 (ja) 2018-07-25 2024-09-24 ノバルティス アーゲー Ｎｌｒｐ３インフラマソーム阻害剤
KR102874906B1 (ko) 2018-12-14 2025-10-21 치아타이 티안큉 파마수티컬 그룹 주식회사 Syk 억제제의 염 및 이의 결정형
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BR112022005575A2 (pt) * 2019-10-09 2022-06-21 Principia Biopharma Inc Métodos de tratar pênfigo por administração de (r)-2-[3-[4-amino-3-(2-fluoro-4-fenóxi-fenil)pirazolo[3,4-d]pirimidin-1-il]piperidina-1-carbonil]-4-metil-4-[4-(oxetan-3-il)piperazin-1-il]pent-2-enonitrila
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EP4193995A4 (en) * 2020-08-10 2024-08-21 Jiangsu Hengrui Pharmaceuticals Co., Ltd. USE OF BTK INHIBITORS TO TREAT DISEASES
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KR102515813B1 (ko) 2023-03-30
MX390619B (es) 2025-03-21
CN115054586B (zh) 2024-08-02
AU2017290354B8 (en) 2023-01-12
CN115054586A (zh) 2022-09-16
US20240207275A1 (en) 2024-06-27
KR20190025947A (ko) 2019-03-12
KR102391693B1 (ko) 2022-04-29
IL263815B (en) 2022-07-01
MA45547A (fr) 2019-05-08
BR112018077503A2 (pt) 2019-04-09
IL293621B2 (en) 2023-09-01
IL293621B1 (en) 2023-05-01
KR20220054906A (ko) 2022-05-03
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IL293621A (en) 2022-08-01
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US20210113567A1 (en) 2021-04-22
IL263815A (en) 2019-01-31
EP3478273A1 (en) 2019-05-08
WO2018005849A1 (en) 2018-01-04
CN109600989A (zh) 2019-04-09
CA3028169C (en) 2024-11-12
JP7129704B2 (ja) 2022-09-02
US12336999B2 (en) 2025-06-24
US11872229B2 (en) 2024-01-16
EA201892836A1 (ru) 2019-07-31
SG11201811255WA (en) 2019-01-30
AU2017290354B2 (en) 2022-12-22
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