KR102391693B1 - 2-[3-[4-아미노-3-(2-플루오로-4-페녹시-페닐)피라졸로[3,4-d]피리미딘-1-일]피페리딘-1-카르보닐]-4-메틸-4-[4-(옥세탄-3-일)피페라진-1-일]펜트-2-엔니트릴의 변형 방출 제제 - Google Patents

2-[3-[4-아미노-3-(2-플루오로-4-페녹시-페닐)피라졸로[3,4-d]피리미딘-1-일]피페리딘-1-카르보닐]-4-메틸-4-[4-(옥세탄-3-일)피페라진-1-일]펜트-2-엔니트릴의 변형 방출 제제 Download PDF

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KR102391693B1
KR102391693B1 KR1020197002895A KR20197002895A KR102391693B1 KR 102391693 B1 KR102391693 B1 KR 102391693B1 KR 1020197002895 A KR1020197002895 A KR 1020197002895A KR 20197002895 A KR20197002895 A KR 20197002895A KR 102391693 B1 KR102391693 B1 KR 102391693B1
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oral dosage
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solid oral
release solid
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KR20190025947A (ko
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아부 제이. 페르두스
모함마드 알. 마세디자데
우 린
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프린시피아 바이오파마, 인코퍼레이티드
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KR1020197002895A 2016-06-29 2017-06-29 2-[3-[4-아미노-3-(2-플루오로-4-페녹시-페닐)피라졸로[3,4-d]피리미딘-1-일]피페리딘-1-카르보닐]-4-메틸-4-[4-(옥세탄-3-일)피페라진-1-일]펜트-2-엔니트릴의 변형 방출 제제 Active KR102391693B1 (ko)

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KR1020227013784A KR102515813B1 (ko) 2016-06-29 2017-06-29 2-[3-[4-아미노-3-(2-플루오로-4-페녹시-페닐)피라졸로[3,4-d]피리미딘-1-일]피페리딘-1-카르보닐]-4-메틸-4-[4-(옥세탄-3-일)피페라진-1-일]펜트-2-엔니트릴의 변형 방출 제제

Applications Claiming Priority (3)

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US201662356345P 2016-06-29 2016-06-29
US62/356,345 2016-06-29
PCT/US2017/040075 WO2018005849A1 (en) 2016-06-29 2017-06-29 Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

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KR1020227013784A Division KR102515813B1 (ko) 2016-06-29 2017-06-29 2-[3-[4-아미노-3-(2-플루오로-4-페녹시-페닐)피라졸로[3,4-d]피리미딘-1-일]피페리딘-1-카르보닐]-4-메틸-4-[4-(옥세탄-3-일)피페라진-1-일]펜트-2-엔니트릴의 변형 방출 제제

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KR20190025947A KR20190025947A (ko) 2019-03-12
KR102391693B1 true KR102391693B1 (ko) 2022-04-29

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KR1020227013784A Active KR102515813B1 (ko) 2016-06-29 2017-06-29 2-[3-[4-아미노-3-(2-플루오로-4-페녹시-페닐)피라졸로[3,4-d]피리미딘-1-일]피페리딘-1-카르보닐]-4-메틸-4-[4-(옥세탄-3-일)피페라진-1-일]펜트-2-엔니트릴의 변형 방출 제제
KR1020197002895A Active KR102391693B1 (ko) 2016-06-29 2017-06-29 2-[3-[4-아미노-3-(2-플루오로-4-페녹시-페닐)피라졸로[3,4-d]피리미딘-1-일]피페리딘-1-카르보닐]-4-메틸-4-[4-(옥세탄-3-일)피페라진-1-일]펜트-2-엔니트릴의 변형 방출 제제

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KR1020227013784A Active KR102515813B1 (ko) 2016-06-29 2017-06-29 2-[3-[4-아미노-3-(2-플루오로-4-페녹시-페닐)피라졸로[3,4-d]피리미딘-1-일]피페리딘-1-카르보닐]-4-메틸-4-[4-(옥세탄-3-일)피페라진-1-일]펜트-2-엔니트릴의 변형 방출 제제

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US (3) US20190231784A1 (enExample)
EP (1) EP3478273A1 (enExample)
JP (1) JP7129704B2 (enExample)
KR (2) KR102515813B1 (enExample)
CN (2) CN109600989B (enExample)
AU (2) AU2017290354C1 (enExample)
CA (1) CA3028169C (enExample)
EA (1) EA201892836A1 (enExample)
IL (2) IL293621B2 (enExample)
MA (1) MA45547A (enExample)
MX (2) MX390619B (enExample)
NZ (1) NZ749662A (enExample)
SG (1) SG11201811255WA (enExample)
WO (1) WO2018005849A1 (enExample)

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PL2892900T3 (pl) 2012-09-10 2018-02-28 Principia Biopharma Inc. Związki pyrazolopirymidonowe jako inhibitory kinazy
CA2939186C (en) 2014-02-21 2023-03-07 Principia Biopharma Inc. Salts and solid form of a btk inhibitor
US10485797B2 (en) 2014-12-18 2019-11-26 Principia Biopharma Inc. Treatment of pemphigus
MA42242A (fr) 2015-06-24 2018-05-02 Principia Biopharma Inc Inhibiteurs de la tyrosine kinase
MX390619B (es) 2016-06-29 2025-03-21 Principia Biopharma Inc Formulaciones de liberacion modificada de 2-[3-[4-amino-3-(2-fluoro-4-fenoxi-fenil)pirazolo[3,4-d]pirimidin-1-il]piperidina-1-carbonil]-4-metil-4-[4-(oxetan-3-il)piperazin-1-il]pent-2-enenitrilo
CN112424207B (zh) 2018-07-25 2024-03-19 诺华股份有限公司 Nlrp3炎性小体抑制剂
US12187710B2 (en) 2018-12-14 2025-01-07 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Salt of Syk inhibitor and crystalline form thereof
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