AU2017283713B2 - Type VI CRISPR orthologs and systems - Google Patents

Type VI CRISPR orthologs and systems Download PDF

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Publication number
AU2017283713B2
AU2017283713B2 AU2017283713A AU2017283713A AU2017283713B2 AU 2017283713 B2 AU2017283713 B2 AU 2017283713B2 AU 2017283713 A AU2017283713 A AU 2017283713A AU 2017283713 A AU2017283713 A AU 2017283713A AU 2017283713 B2 AU2017283713 B2 AU 2017283713B2
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rna
cell
composition
nucleic acid
vitro
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AU2017283713A1 (en
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Omar O. Abudayyeh
Jonathan Gootenberg
Eric S. Lander
Feng Zhang
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Harvard College
Massachusetts Institute of Technology
Broad Institute Inc
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Harvard College
Massachusetts Institute of Technology
Broad Institute Inc
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Priority to AU2021203747A priority patent/AU2021203747B2/en
Priority to AU2023204078A priority patent/AU2023204078A1/en
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
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    • C12N15/102Mutagenizing nucleic acids
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213Targeted insertion of genes into the plant genome by homologous recombination
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/20Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
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    • C12N2800/00Nucleic acids vectors
    • C12N2800/22Vectors comprising a coding region that has been codon optimised for expression in a respective host

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  • Wood Science & Technology (AREA)
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  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
AU2017283713A 2016-06-17 2017-06-19 Type VI CRISPR orthologs and systems Active AU2017283713B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2018271372A AU2018271372A1 (en) 2016-06-17 2018-11-30 Type VI CRISPR orthologs and systems
AU2021203747A AU2021203747B2 (en) 2016-06-17 2021-06-07 Novel Type VI CRISPR orthologs and systems
AU2023204078A AU2023204078A1 (en) 2016-06-17 2023-06-27 Novel Type VI CRISPR orthologs and systems

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US201662351803P 2016-06-17 2016-06-17
US201662351662P 2016-06-17 2016-06-17
US62/351,662 2016-06-17
US62/351,803 2016-06-17
US201662376377P 2016-08-17 2016-08-17
US62/376,377 2016-08-17
US201662410366P 2016-10-19 2016-10-19
US62/410,366 2016-10-19
US201662432240P 2016-12-09 2016-12-09
US62/432,240 2016-12-09
US201762471792P 2017-03-15 2017-03-15
US62/471,792 2017-03-15
US201762484786P 2017-04-12 2017-04-12
US62/484,786 2017-04-12
PCT/US2017/038154 WO2017219027A1 (en) 2016-06-17 2017-06-19 Type vi crispr orthologs and systems

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018271372A Division AU2018271372A1 (en) 2016-06-17 2018-11-30 Type VI CRISPR orthologs and systems

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AU2017283713A1 AU2017283713A1 (en) 2018-12-20
AU2017283713B2 true AU2017283713B2 (en) 2021-04-08

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AU2017283713A Active AU2017283713B2 (en) 2016-06-17 2017-06-19 Type VI CRISPR orthologs and systems
AU2018271372A Abandoned AU2018271372A1 (en) 2016-06-17 2018-11-30 Type VI CRISPR orthologs and systems
AU2021203747A Active AU2021203747B2 (en) 2016-06-17 2021-06-07 Novel Type VI CRISPR orthologs and systems
AU2023204078A Pending AU2023204078A1 (en) 2016-06-17 2023-06-27 Novel Type VI CRISPR orthologs and systems

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AU2018271372A Abandoned AU2018271372A1 (en) 2016-06-17 2018-11-30 Type VI CRISPR orthologs and systems
AU2021203747A Active AU2021203747B2 (en) 2016-06-17 2021-06-07 Novel Type VI CRISPR orthologs and systems
AU2023204078A Pending AU2023204078A1 (en) 2016-06-17 2023-06-27 Novel Type VI CRISPR orthologs and systems

Country Status (9)

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US (2) US11788083B2 (ja)
EP (1) EP3455357A1 (ja)
JP (3) JP7267013B2 (ja)
KR (2) KR20190019168A (ja)
CN (1) CN109642231A (ja)
AU (4) AU2017283713B2 (ja)
BR (1) BR112018076190A2 (ja)
CA (1) CA3028158A1 (ja)
WO (1) WO2017219027A1 (ja)

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