AU2015372767B2 - Glucagon derivatives - Google Patents

Glucagon derivatives Download PDF

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Publication number
AU2015372767B2
AU2015372767B2 AU2015372767A AU2015372767A AU2015372767B2 AU 2015372767 B2 AU2015372767 B2 AU 2015372767B2 AU 2015372767 A AU2015372767 A AU 2015372767A AU 2015372767 A AU2015372767 A AU 2015372767A AU 2015372767 B2 AU2015372767 B2 AU 2015372767B2
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AU
Australia
Prior art keywords
lys
peptide
xaa
glu
artificial sequence
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AU2015372767A
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AU2015372767A1 (en
Inventor
Jae Hyuk Choi
Sung Youb Jung
Se Chang Kwon
Jong Suk Lee
Chang Ki Lim
Young Jin Park
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Hanmi Pharmaceutical Co Ltd
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Hanmi Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2015372767A 2014-12-30 2015-12-30 Glucagon derivatives Active AU2015372767B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020140193691A KR102418477B1 (ko) 2014-12-30 2014-12-30 글루카곤 유도체
KR10-2014-0193691 2014-12-30
PCT/KR2015/014481 WO2016108617A1 (en) 2014-12-30 2015-12-30 Glucagon derivatives

Publications (2)

Publication Number Publication Date
AU2015372767A1 AU2015372767A1 (en) 2017-07-13
AU2015372767B2 true AU2015372767B2 (en) 2020-07-16

Family

ID=56284668

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015372767A Active AU2015372767B2 (en) 2014-12-30 2015-12-30 Glucagon derivatives

Country Status (18)

Country Link
US (3) US10513550B2 (cg-RX-API-DMAC10.html)
EP (1) EP3240802B1 (cg-RX-API-DMAC10.html)
JP (1) JP6758297B2 (cg-RX-API-DMAC10.html)
KR (1) KR102418477B1 (cg-RX-API-DMAC10.html)
CN (1) CN107250155B (cg-RX-API-DMAC10.html)
AR (1) AR103323A1 (cg-RX-API-DMAC10.html)
AU (1) AU2015372767B2 (cg-RX-API-DMAC10.html)
BR (1) BR112017013845A2 (cg-RX-API-DMAC10.html)
CA (1) CA2972001C (cg-RX-API-DMAC10.html)
EA (1) EA036479B1 (cg-RX-API-DMAC10.html)
IL (1) IL253001B (cg-RX-API-DMAC10.html)
MX (1) MX389593B (cg-RX-API-DMAC10.html)
PH (1) PH12017501205A1 (cg-RX-API-DMAC10.html)
SG (2) SG10201906912VA (cg-RX-API-DMAC10.html)
TW (1) TWI696631B (cg-RX-API-DMAC10.html)
UA (1) UA122967C2 (cg-RX-API-DMAC10.html)
WO (1) WO2016108617A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201704328B (cg-RX-API-DMAC10.html)

Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
KR102291020B1 (ko) * 2014-12-30 2021-08-20 한미약품 주식회사 안정성이 증가된 글루카곤 유도체
FI3322437T3 (fi) 2015-06-30 2024-02-20 Hanmi Pharmaceutical Co Ltd Glukagonijohdannainen ja sen pitkävaikutteisen konjugaatin käsittävä koostumus
TWI622596B (zh) 2015-10-26 2018-05-01 美國禮來大藥廠 升糖素受體促效劑
JP6712323B2 (ja) 2015-12-31 2020-06-17 ハンミ ファーマシューティカル カンパニー リミテッド グルカゴン、ｇｌｐ−１及びｇｉｐ受容体のすべてに活性を有する三重活性体
BR112021000933A2 (pt) * 2018-07-19 2021-04-27 D&D Pharmatech Inc. polipeptídeo, composição farmacêutica, método de preparação dela e método de prevenção ou tratamento de doenças
JP2025526148A (ja) 2022-08-18 2025-08-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 長時間作用型ｇｌｐ－１／グルカゴン受容体アゴニスト及びｎｐｙ２受容体アゴニストを含む組合せ治療

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