AU2015301632B2 - Signal amplification in plasmonic specific-binding partner assays - Google Patents

Signal amplification in plasmonic specific-binding partner assays Download PDF

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Publication number
AU2015301632B2
AU2015301632B2 AU2015301632A AU2015301632A AU2015301632B2 AU 2015301632 B2 AU2015301632 B2 AU 2015301632B2 AU 2015301632 A AU2015301632 A AU 2015301632A AU 2015301632 A AU2015301632 A AU 2015301632A AU 2015301632 B2 AU2015301632 B2 AU 2015301632B2
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metallic
nanostructures
lspr
gold
analyte
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AU2015301632A1 (en
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Kenneth P. Aron
Vincent Chiang
Asher KRELL
Rajesh K. Mehra
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Zoetis Services LLC
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Zoetis Services LLC
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553Metal or metal coated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2015301632A 2014-08-13 2015-08-13 Signal amplification in plasmonic specific-binding partner assays Active AU2015301632B2 (en)

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AU2021202253A AU2021202253B2 (en) 2014-08-13 2021-04-14 Signal amplification in plasmonic specific-binding partner assays
AU2023270256A AU2023270256B2 (en) 2014-08-13 2023-11-22 Signal amplification in plasmonic specific-binding partner assays

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US201462037071P 2014-08-13 2014-08-13
US62/037,071 2014-08-13
US201462082468P 2014-11-20 2014-11-20
US62/082,468 2014-11-20
PCT/US2015/045041 WO2016025703A2 (en) 2014-08-13 2015-08-13 Signal amplification in plasmonic specific-binding partner assays

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US (3) US10488409B2 (https=)
EP (2) EP3943943A1 (https=)
JP (3) JP6945445B2 (https=)
KR (2) KR102497598B1 (https=)
CN (2) CN106796228B (https=)
AU (3) AU2015301632B2 (https=)
CA (2) CA3209879A1 (https=)
DK (1) DK3180619T3 (https=)
ES (1) ES2888230T3 (https=)
HU (1) HUE056514T2 (https=)
IL (4) IL300266B2 (https=)
MX (2) MX2017001905A (https=)
PL (1) PL3180619T3 (https=)
PT (1) PT3180619T (https=)
SG (2) SG10201901240TA (https=)
TW (1) TWI691716B (https=)
WO (1) WO2016025703A2 (https=)
ZA (1) ZA201700873B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3489685T (pt) 2011-11-21 2024-01-04 Zoetis Services Llc Amplificação de sinais em imunoensaios de fluxo lateral e relacionados
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
WO2016187588A1 (en) * 2015-05-21 2016-11-24 Lamdagen Corporation Plasmonic nanoparticles and lspr-based assays
EP4465021A3 (en) 2015-08-04 2025-02-26 Zoetis Services LLC Signal amplification in solution-based plasmonic specific-binding partner assays
JP2017150865A (ja) * 2016-02-23 2017-08-31 コニカミノルタ株式会社 ガス検知方法及びガス検知装置
KR101842763B1 (ko) * 2016-03-11 2018-05-14 경희대학교 산학협력단 구리 나노구조물의 제조방법
WO2018140953A1 (en) 2017-01-30 2018-08-02 Abaxis, Inc. Solution-based plasmon specific-binding partner assays and metallic nanostructures
JP6926731B2 (ja) * 2017-06-30 2021-08-25 コニカミノルタ株式会社 検出チップ、検出キット、検出システムおよび被検出物質の検出方法
EP3775896B1 (en) * 2018-04-03 2023-06-07 Sanofi Lateral flow immunoassay strip device
CN111024942B (zh) * 2019-11-27 2023-06-02 北京农业智能装备技术研究中心 一种免疫层析试纸条的高灵敏检测方法
CA3215851A1 (en) * 2021-04-21 2022-10-27 Udayan Kanade System and method for simulating a localized surface plasmon resonance (lspr) spectrometer
CN120936679A (zh) 2023-03-17 2025-11-11 贝克曼库尔特有限公司 苯并噻吩并吡咯花菁染料
WO2025014842A1 (en) * 2023-07-07 2025-01-16 Ohio University Test strips and methods of testing for bio-analytes using titanium nitride nanoparticles and gold coated copper nanoparticles
EP4567426A1 (en) * 2023-12-05 2025-06-11 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) A nanoparticle, a suspension comprising nanoparticles, and related method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100062545A1 (en) * 2005-06-15 2010-03-11 University Of Maryland Biotechnology Institute Bioassays using plasmonic scattering from noble metal nanostructures
US20130034854A1 (en) * 2010-04-27 2013-02-07 Ventana Medical Systems, Inc. Antibody-Nanoparticle Conjugates and Methods for Making and Using Such Conjugates

Family Cites Families (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704366A (en) 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
JPH03164195A (ja) * 1989-11-22 1991-07-16 Idemitsu Petrochem Co Ltd 液体試料の分析方法及び分析装置
US5061381A (en) 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
US5186844A (en) 1991-04-01 1993-02-16 Abaxis, Inc. Apparatus and method for continuous centrifugal blood cell separation
US5122284A (en) 1990-06-04 1992-06-16 Abaxis, Inc. Apparatus and method for optically analyzing biological fluids
US5413732A (en) 1991-08-19 1995-05-09 Abaxis, Inc. Reagent compositions for analytical testing
US5304348A (en) 1992-02-11 1994-04-19 Abaxis, Inc. Reagent container for analytical rotor
AU4047493A (en) 1992-04-02 1993-11-08 Abaxis, Inc. Analytical rotor with dye mixing chamber
JP3706214B2 (ja) 1996-10-28 2005-10-12 株式会社三菱化学ヤトロン 免疫学的分析方法
US5939021A (en) 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
US6180415B1 (en) 1997-02-20 2001-01-30 The Regents Of The University Of California Plasmon resonant particles, methods and apparatus
US7144627B2 (en) 1997-03-12 2006-12-05 William Marsh Rice University Multi-layer nanoshells comprising a metallic or conducting shell
US6344272B1 (en) 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US6699724B1 (en) 1998-03-11 2004-03-02 Wm. Marsh Rice University Metal nanoshells for biosensing applications
JP2000028612A (ja) 1998-07-07 2000-01-28 Nitto Denko Corp 免疫学的検査方法および免疫学的検査キット
JP3841559B2 (ja) 1998-07-07 2006-11-01 日東電工株式会社 免疫学的検査方法および免疫学的検査キット
JP3298836B2 (ja) 1998-11-12 2002-07-08 アークレイ株式会社 検体分析用具
US6579726B1 (en) 1999-07-30 2003-06-17 Surromed, Inc. Instruments, methods and reagents for surface plasmon resonance
EP1236034A4 (en) 1999-11-12 2006-05-03 Surromed Inc PLASMON RESONANCE SURFACE BIODETECTION
WO2002079764A1 (en) 2001-01-26 2002-10-10 Nanoplex Technologies, Inc. Surface-enhanced spectroscopy-active sandwich nanoparticles
WO2002059226A2 (en) 2000-11-03 2002-08-01 Wm. Marsh Rice University Partial coverage metal nanoshells and method of making same
US7238472B2 (en) * 2001-05-25 2007-07-03 Nanosphere, Inc. Non-alloying core shell nanoparticles
US7135054B2 (en) 2001-09-26 2006-11-14 Northwestern University Nanoprisms and method of making them
CN1417586A (zh) 2001-11-05 2003-05-14 福州市迈新生物技术开发公司 一种免疫检测信号放大系统和它的制备方法及其应用
US6970239B2 (en) 2002-06-12 2005-11-29 Intel Corporation Metal coated nanocrystalline silicon as an active surface enhanced Raman spectroscopy (SERS) substrate
US7212692B2 (en) 2002-11-08 2007-05-01 Ming Yan Multiple array surface plasmon resonance biosensor
JP4787938B2 (ja) 2003-03-28 2011-10-05 ザ・プロウボウスト・フェロウズ・ファウンデーション・スカラーズ・アンド・ザ・アザー・メンバーズ・オブ・ボード・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン 銀ナノ粒子を用いた検体検出用センサ
KR100531760B1 (ko) 2003-04-28 2005-11-29 대한민국(관리부서 : 농림부 국립수의과학검역원) 구제역 바이러스의 감염여부를 진단하는 방법 및 이를구현하기 위한 진단키트
US20060240573A1 (en) 2003-07-29 2006-10-26 Lamdagen, Llc Optical system including nanostructures for biological or chemical sensing
GB0321937D0 (en) * 2003-09-19 2003-10-22 Univ Liverpool Nanoparticle conjugates and method of production thereof
EP1692514A4 (en) * 2003-11-07 2008-04-09 Hepgenics Pty Ltd BINDING ASSAY COMPONENTS
JP4109205B2 (ja) * 2004-01-07 2008-07-02 富士フイルム株式会社 被検体検出方法
EP1836495A2 (en) 2004-11-17 2007-09-26 BioVeris Corporation Electrochemiluminescent assay
CN1296492C (zh) 2004-11-18 2007-01-24 博奥生物有限公司 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法
US7405054B1 (en) 2004-12-13 2008-07-29 University Of Washington Uw Tech Transfer - Invention Licensing Signal amplification method for surface plasmon resonance-based chemical detection
US8628727B2 (en) 2005-04-08 2014-01-14 Northwestern University Compositions, devices and methods for SERS and LSPR
US20060246513A1 (en) 2005-05-02 2006-11-02 Bohannon Robert C Method and device to detect the presence of analytes in a sample
US20070092978A1 (en) 2005-10-20 2007-04-26 Ronald Mink Target ligand detection
JP5442179B2 (ja) 2005-10-21 2014-03-12 アルフレッサファーマ株式会社 反応性物質が結合した微小粒子の沈降抑制方法および該微小粒子含有試薬
CA2627376C (en) 2005-10-25 2016-07-05 Donald Templeton Haynie Immunogenic compositions and methods of use
US7888043B2 (en) 2005-11-18 2011-02-15 The United States Of America As Represented By The Department Of Health And Human Services, Centers For Disease Control And Prevention Modified cardiolipin and uses therefor
WO2007103802A2 (en) 2006-03-03 2007-09-13 William Marsh Rice University Nanorice particles: hybrid plasmonic nanostructures
JP4810304B2 (ja) 2006-05-12 2011-11-09 キヤノン株式会社 化学センサ素子及びその製造方法
JP2010533281A (ja) * 2006-06-06 2010-10-21 ビバクタ、リミテッド 化学物質の検知方法
US8426152B2 (en) * 2007-01-03 2013-04-23 Lamdagen Corporation Enzymatic assay for LSPR
ES2635272T3 (es) 2007-03-20 2017-10-03 Becton, Dickinson And Company Ensayo que usa partículas activas en espectroscopia Raman potenciada en superficie (SERS)
JP2009150708A (ja) * 2007-12-19 2009-07-09 Canon Inc 標的物質の検出方法及び検査キット
US8808420B2 (en) 2007-12-21 2014-08-19 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin Process for preparing nanoparticles
US8137920B2 (en) 2008-03-20 2012-03-20 Abaxis, Inc. Multi-wavelength analyses of sol-particle specific binding assays
WO2010006201A2 (en) 2008-07-10 2010-01-14 Abaxis, Inc. Methods of reducing non-specific interaction in metal nanoparticle assays
US8846319B2 (en) 2008-12-03 2014-09-30 Abaxis, Inc. Lateral flow strip assay with immobilized conjugate
US8313915B2 (en) 2009-01-21 2012-11-20 Gundersen Lutheran Medical Foundation, Inc. Early detection of canine lyme disease by specific peptides and antibodies
WO2010091293A1 (en) 2009-02-06 2010-08-12 The Regents Of The University Of California Plasmonic system for detecting binding of biological molecules
CA2753598C (en) 2009-02-27 2018-07-10 Beckman Coulter, Inc. Solution phase homogeneous assays
WO2010116346A1 (en) 2009-04-08 2010-10-14 National University Of Ireland, Galway Silver nanoplates
JP5563789B2 (ja) * 2009-06-11 2014-07-30 富士フイルム株式会社 検出方法
AU2010322085B2 (en) 2009-11-17 2016-09-15 Zoetis Services Llc Peptides and methods for the detection of Lyme disease antibodies
JP6161291B2 (ja) 2009-11-20 2017-07-12 アバクシス, インコーポレイテッド エールリッヒア抗体の検出のためのペプチド、装置、および方法
WO2011065747A2 (ko) 2009-11-24 2011-06-03 한국생명공학연구원 나노입자를 이용한 미생물의 고속 검출방법
US9308582B2 (en) 2009-12-24 2016-04-12 Yi Sun Solution stable and chemically reactive metallic nanoparticles
EP2354792A1 (en) 2010-02-08 2011-08-10 Biomonitor A/S Method for detecting anti-drug antibodies
US20130071619A1 (en) * 2010-05-28 2013-03-21 Nippon Steel & Sumikin Chemical Co., Ltd. Metal fine-particle composite and method for fabricating the same
WO2012077756A1 (ja) * 2010-12-08 2012-06-14 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した被検出物質の検出装置および方法
CN102103145B (zh) 2011-02-24 2013-01-16 南京基蛋生物科技有限公司 一种双放大系统的胶体金试纸条及其制备方法
US8697129B2 (en) 2011-03-02 2014-04-15 Imra America, Inc. Stable colloidal gold nanoparticles with controllable surface modification and functionalization
WO2012125693A2 (en) 2011-03-15 2012-09-20 Northwestern University Multifunctional metal nanoparticles having a polydopamine-based surface and methods of making and using the same
US20130230717A1 (en) 2011-09-02 2013-09-05 Washington University In St. Louis Copper nanostructures and methods for their preparation
US8758772B2 (en) 2011-11-04 2014-06-24 Abaxis, Inc. Peptides and methods for the detection of lyme disease antibodies
PT3489685T (pt) 2011-11-21 2024-01-04 Zoetis Services Llc Amplificação de sinais em imunoensaios de fluxo lateral e relacionados
US9823246B2 (en) 2011-12-28 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon
US20130189793A1 (en) 2012-01-20 2013-07-25 Wei Qian Stable Colloidal Suspensions Of Gold Nanoconjugates And The Method For Preparing The Same
US20150017258A1 (en) 2012-01-31 2015-01-15 American University Of Cairo (Auc) Direct detection of disease biomarkers in clinical specimens using cationic nanoparticle-based assays & versatile and green methods for synthesis of anisotropic silver nanostructures
EP2625966A1 (en) 2012-02-13 2013-08-14 Bionanoplus, S.L. Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof
TWI435843B (zh) 2012-04-27 2014-05-01 Univ Nat Taiwan 奈米顆粒的製造方法
WO2013169640A1 (en) 2012-05-05 2013-11-14 Academia Sinica Diaminobenzoic or ortho-phenylene diamine conjugated peptides as functional saccharide tagging reagents
CA2887687A1 (en) 2012-10-11 2014-04-17 Nanocomposix, Inc. Silver nanoplate compositions and methods
BR112015008036B1 (pt) * 2012-10-11 2022-09-13 Zoetis Services Llc População de peptídeos isolados, método para detectar em uma amostra um anticorpo, método para diagnosticar erliquiose monocítica e/ou granulocítica, método para detectar a presença de anticorpos e kit
US9441301B2 (en) 2012-12-06 2016-09-13 Nanyang Technological University Method for forming a bimetallic core-shell nanostructure
BR112015023239A8 (pt) 2013-03-14 2018-04-17 Abbott Lab ensaio de combinação de anticorpo-antígeno de hcv e métodos e composições para uso do mesmo
JP2016512241A (ja) 2013-03-14 2016-04-25 アボット・ラボラトリーズAbbott Laboratories 改良された抗体検出のためのhcvns3組換え抗原およびこの突然変異体
US20160120978A1 (en) 2013-06-05 2016-05-05 Purdue Research Foundation Titanium nitride plasmonic nanoparticles for clinical therapeutic applications
CN105393119A (zh) 2013-07-30 2016-03-09 生物辐射实验室股份有限公司 用于免疫试验的多重封闭物珠
KR20160138059A (ko) 2014-02-26 2016-12-02 람다젠 코퍼레이션 향상된 검정 감도를 위한 디지털 lspr
US10024800B2 (en) 2014-04-15 2018-07-17 Rutgers, The State University Of New Jersey Gold nanostar substrates for SERS sensing in the femtomolar regime
US10518331B2 (en) 2014-07-11 2019-12-31 Northwestern University Synthesis of uniform anisotropic nanoparticles
CN105492605A (zh) 2014-08-01 2016-04-13 比科尔公司 用于免疫检验的病毒样颗粒、用于所述免疫检验的封闭剂、及包含它们的试剂盒
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
CA2976963A1 (en) 2015-02-19 2016-08-25 Ionica Sciences Reagents and methods for detecting infectious diseases
WO2016170183A1 (en) 2015-04-24 2016-10-27 Pharmadiagnostics Nv Improved method of measuring an interaction between molecules
EP4465021A3 (en) 2015-08-04 2025-02-26 Zoetis Services LLC Signal amplification in solution-based plasmonic specific-binding partner assays
WO2018140953A1 (en) 2017-01-30 2018-08-02 Abaxis, Inc. Solution-based plasmon specific-binding partner assays and metallic nanostructures

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100062545A1 (en) * 2005-06-15 2010-03-11 University Of Maryland Biotechnology Institute Bioassays using plasmonic scattering from noble metal nanostructures
US20130034854A1 (en) * 2010-04-27 2013-02-07 Ventana Medical Systems, Inc. Antibody-Nanoparticle Conjugates and Methods for Making and Using Such Conjugates

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BOLDUC O.R. ET AL., "Advances in surface plasmon resonance sensing with nanoparticles and thin films: Nanomaterials, surface chemistry, and hybrid plasmonic techniques" ANAL. CHEM. (2011) vol. 83, no. 21, pages 8057-8062 *
CUI Y. ET AL., "Synthesis of AgcoreAushell Bimetallic Nanoparticles for Immunoassay Based on Surface Enhanced Raman Spectroscopy", J. PHYS. CHEM. B, (2006-02-04), vol. 110, pages 4002-4006 *
CUI Y. ET AL., "Synthesis of AgcoreAushell Bimetallic Nanoparticles for Immunoassay Based on Surface-Enhanced Raman Spectroscopy", J. PHYS. CHEM. B, (2006-02-04), vol. 110, pages 4002-4006 *
DONG P. ET AL., "Ultrathin gold-shell coated silver nanoparticles onto a glass platform for improvement of plasmonic sensors", ACS APPL. MATER. INTERFACES, (2013-03-11), vol. 5, no. 7, pages 2392 - 2399 *
HAES A. ET AL., "Nanoscale plasmonics begins to unravel Alzheimer’s disease", LASER FOCUS WORLD, (2005-06-01) *

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