AU2014264228A1 - Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose - Google Patents

Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose Download PDF

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Publication number
AU2014264228A1
AU2014264228A1 AU2014264228A AU2014264228A AU2014264228A1 AU 2014264228 A1 AU2014264228 A1 AU 2014264228A1 AU 2014264228 A AU2014264228 A AU 2014264228A AU 2014264228 A AU2014264228 A AU 2014264228A AU 2014264228 A1 AU2014264228 A1 AU 2014264228A1
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AU
Australia
Prior art keywords
trehalose
pharmaceutical formulation
administration
once
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2014264228A
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English (en)
Inventor
Dalia Megiddo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enlivex Therapeutics Ltd
Original Assignee
Bio Blast Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Blast Pharma Ltd filed Critical Bio Blast Pharma Ltd
Publication of AU2014264228A1 publication Critical patent/AU2014264228A1/en
Priority to AU2019204513A priority Critical patent/AU2019204513B2/en
Priority to AU2020277197A priority patent/AU2020277197A1/en
Priority to AU2023200303A priority patent/AU2023200303A1/en
Priority to AU2025201824A priority patent/AU2025201824A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04Disaccharides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2014264228A 2013-05-07 2014-05-07 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose Abandoned AU2014264228A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2019204513A AU2019204513B2 (en) 2013-05-07 2019-06-26 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2020277197A AU2020277197A1 (en) 2013-05-07 2020-11-26 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2023200303A AU2023200303A1 (en) 2013-05-07 2023-01-20 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2025201824A AU2025201824A1 (en) 2013-05-07 2025-03-13 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361820278P 2013-05-07 2013-05-07
US61/820,278 2013-05-07
PCT/IL2014/050411 WO2014181333A2 (en) 2013-05-07 2014-05-07 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2019204513A Division AU2019204513B2 (en) 2013-05-07 2019-06-26 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose

Publications (1)

Publication Number Publication Date
AU2014264228A1 true AU2014264228A1 (en) 2015-11-12

Family

ID=51022384

Family Applications (5)

Application Number Title Priority Date Filing Date
AU2014264228A Abandoned AU2014264228A1 (en) 2013-05-07 2014-05-07 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2019204513A Active AU2019204513B2 (en) 2013-05-07 2019-06-26 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2020277197A Abandoned AU2020277197A1 (en) 2013-05-07 2020-11-26 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2023200303A Abandoned AU2023200303A1 (en) 2013-05-07 2023-01-20 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2025201824A Pending AU2025201824A1 (en) 2013-05-07 2025-03-13 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose

Family Applications After (4)

Application Number Title Priority Date Filing Date
AU2019204513A Active AU2019204513B2 (en) 2013-05-07 2019-06-26 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2020277197A Abandoned AU2020277197A1 (en) 2013-05-07 2020-11-26 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2023200303A Abandoned AU2023200303A1 (en) 2013-05-07 2023-01-20 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose
AU2025201824A Pending AU2025201824A1 (en) 2013-05-07 2025-03-13 Treatment of protein aggregation myopathic and neurodegenerative diseases by parenteral administration of trehalose

Country Status (14)

Country Link
US (5) US10493023B2 (https=)
EP (2) EP2994145B1 (https=)
JP (5) JP6837835B2 (https=)
KR (1) KR20160009617A (https=)
AU (5) AU2014264228A1 (https=)
CA (2) CA3239805A1 (https=)
CR (1) CR20150637A (https=)
EA (1) EA201501054A1 (https=)
IL (1) IL241757B (https=)
MD (1) MD20150120A2 (https=)
MX (1) MX2015015355A (https=)
PE (1) PE20160012A1 (https=)
SG (1) SG11201509030TA (https=)
WO (1) WO2014181333A2 (https=)

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Also Published As

Publication number Publication date
US20240009113A1 (en) 2024-01-11
US20220117883A1 (en) 2022-04-21
JP2021152032A (ja) 2021-09-30
CA2911399C (en) 2024-09-10
SG11201509030TA (en) 2015-11-27
CR20150637A (es) 2016-04-05
JP2016518403A (ja) 2016-06-23
EP2994145B1 (en) 2023-01-04
MX2015015355A (es) 2016-07-18
JP2025087858A (ja) 2025-06-10
EA201501054A1 (ru) 2016-04-29
JP2023040211A (ja) 2023-03-22
JP6837835B2 (ja) 2021-03-03
EP2994145A2 (en) 2016-03-16
PE20160012A1 (es) 2016-02-14
CA2911399A1 (en) 2014-11-13
IL241757B (en) 2020-05-31
AU2020277197A1 (en) 2020-12-24
WO2014181333A2 (en) 2014-11-13
US20160120798A1 (en) 2016-05-05
AU2019204513B2 (en) 2020-09-10
US10493023B2 (en) 2019-12-03
EP4218769A3 (en) 2023-10-18
US12239733B2 (en) 2025-03-04
AU2019204513A1 (en) 2019-07-18
US20260014072A1 (en) 2026-01-15
HK1217300A1 (en) 2017-01-06
EP4218769A2 (en) 2023-08-02
MD20150120A2 (ro) 2016-03-31
WO2014181333A3 (en) 2015-01-08
US10869831B2 (en) 2020-12-22
AU2023200303A1 (en) 2023-02-23
AU2025201824A1 (en) 2025-04-03
CA3239805A1 (en) 2014-11-13
JP2019142907A (ja) 2019-08-29
US20190374463A1 (en) 2019-12-12
KR20160009617A (ko) 2016-01-26

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