AU2014243704A1 - Methods and compositions for detecting pancreatic cancer - Google Patents
Methods and compositions for detecting pancreatic cancer Download PDFInfo
- Publication number
- AU2014243704A1 AU2014243704A1 AU2014243704A AU2014243704A AU2014243704A1 AU 2014243704 A1 AU2014243704 A1 AU 2014243704A1 AU 2014243704 A AU2014243704 A AU 2014243704A AU 2014243704 A AU2014243704 A AU 2014243704A AU 2014243704 A1 AU2014243704 A1 AU 2014243704A1
- Authority
- AU
- Australia
- Prior art keywords
- pancreatic cancer
- protein
- level
- cancer biomarker
- homo sapiens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2020202066A AU2020202066B2 (en) | 2013-03-13 | 2020-03-23 | Methods and compositions for detecting pancreatic cancer |
| AU2022224782A AU2022224782A1 (en) | 2013-03-13 | 2022-08-31 | Methods and compositions for detecting pancreatic cancer |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361780574P | 2013-03-13 | 2013-03-13 | |
| US61/780,574 | 2013-03-13 | ||
| PCT/US2014/026857 WO2014160499A2 (en) | 2013-03-13 | 2014-03-13 | Methods and compositions for detecting pancreatic cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020202066A Division AU2020202066B2 (en) | 2013-03-13 | 2020-03-23 | Methods and compositions for detecting pancreatic cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2014243704A1 true AU2014243704A1 (en) | 2015-09-10 |
Family
ID=50933479
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2014243704A Abandoned AU2014243704A1 (en) | 2013-03-13 | 2014-03-13 | Methods and compositions for detecting pancreatic cancer |
| AU2020202066A Ceased AU2020202066B2 (en) | 2013-03-13 | 2020-03-23 | Methods and compositions for detecting pancreatic cancer |
| AU2022224782A Abandoned AU2022224782A1 (en) | 2013-03-13 | 2022-08-31 | Methods and compositions for detecting pancreatic cancer |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2020202066A Ceased AU2020202066B2 (en) | 2013-03-13 | 2020-03-23 | Methods and compositions for detecting pancreatic cancer |
| AU2022224782A Abandoned AU2022224782A1 (en) | 2013-03-13 | 2022-08-31 | Methods and compositions for detecting pancreatic cancer |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20160033511A1 (enExample) |
| EP (1) | EP2972375A2 (enExample) |
| JP (3) | JP6646571B2 (enExample) |
| AU (3) | AU2014243704A1 (enExample) |
| CA (1) | CA2902841A1 (enExample) |
| HK (1) | HK1214652A1 (enExample) |
| WO (1) | WO2014160499A2 (enExample) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2632630C (en) | 2005-12-13 | 2016-12-06 | President And Fellows Of Harvard College | Scaffolds for cell transplantation |
| WO2008117067A2 (en) | 2007-03-27 | 2008-10-02 | Carl Arne Krister Borrebaeck | Protein signature/markers for the detection of adenocarcinoma |
| ES2773858T3 (es) | 2010-10-06 | 2020-07-15 | Harvard College | Hidrogeles formadores de poros inyectables para terapias celulares basadas en materiales |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| US10226238B2 (en) | 2011-09-12 | 2019-03-12 | Creatics Llc | Non-invasive methods of detecting target molecules |
| EP2836512B1 (en) * | 2012-04-11 | 2018-10-24 | F.Hoffmann-La Roche Ag | Improved antibody light chains |
| CN104244929B (zh) | 2012-04-16 | 2017-04-05 | 哈佛学院董事会 | 用于调节免疫反应的介孔二氧化硅组合物 |
| KR20150023904A (ko) | 2012-06-27 | 2015-03-05 | 버그 엘엘씨 | 전립선암의 진단 및 치료에서의 마커의 용도 |
| SMT201700415T1 (it) | 2013-03-15 | 2017-11-15 | Shire Viropharma Inc | Composizioni di c1-inh per l’uso nella prevenzione e nel trattamento dell’angioedema ereditario (hae) |
| WO2014205374A1 (en) * | 2013-06-20 | 2014-12-24 | The Trustees Of The University Of Pennsylvania | Methods for diagnosing pancreatic cancer |
| ES2861600T3 (es) | 2014-04-04 | 2021-10-06 | Mayo Found Medical Education & Res | Isotipaje de inmunoglobulinas usando masa molecular precisa |
| CN107073090A (zh) | 2014-04-30 | 2017-08-18 | 哈佛学院董事会 | 结合的疫苗装置和杀死癌细胞的方法 |
| CN106461678A (zh) * | 2014-05-26 | 2017-02-22 | 奥林巴斯株式会社 | 胰腺癌判定方法 |
| KR20160045547A (ko) * | 2014-10-17 | 2016-04-27 | 에스케이텔레콤 주식회사 | 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단방법 |
| JP6759229B2 (ja) | 2014-12-08 | 2020-09-23 | バーグ エルエルシー | 前立腺癌の診断および処置におけるフィラミンaを含むマーカーの使用 |
| EP3233883B1 (en) | 2014-12-19 | 2019-10-16 | F.Hoffmann-La Roche Ag | Identification of transglutaminase substrates and uses therefor |
| US11054425B2 (en) | 2014-12-19 | 2021-07-06 | Roche Sequencing Solutions, Inc. | System and method for identification and characterization of transglutaminase species |
| CA2971402C (en) | 2014-12-19 | 2023-08-01 | F. Hoffmann-La Roche Ag | Microbial transglutaminases, substrates therefor and methods for the use thereof |
| EP3250250A4 (en) | 2015-01-30 | 2019-05-22 | President and Fellows of Harvard College | PERITUMORAL AND INTRATUMORAL MATERIALS FOR CANCER THERAPY |
| US20160271120A1 (en) * | 2015-03-17 | 2016-09-22 | Oakdene Holdings Llc | Pharmaceutical composition for cleansing of the gastrointestinal tract |
| GB201505654D0 (en) * | 2015-04-01 | 2015-05-13 | Nordic Bioscience As | Immunoassay for collagen type VI sequence |
| WO2016164593A1 (en) * | 2015-04-07 | 2016-10-13 | President And Fellows Of Harvard College | Compositions and methods for modulating hydroxylation of acc2 by phd3 |
| CN114099793A (zh) | 2015-04-10 | 2022-03-01 | 哈佛学院院长等 | 免疫细胞捕获装置及其制备和使用方法 |
| AU2015392603B2 (en) * | 2015-04-20 | 2022-06-02 | Consejo Superior De Investigaciones Cientificas | Agents binding specifically to human cadherin-17, human cadherin-5, human cadherin-6 and human cadherin-20 RGD motif |
| HK1254866A1 (zh) | 2015-06-25 | 2019-07-26 | Immatics Biotechnologies Gmbh | 用於骨髓瘤和其他癌症免疫治疗的新型细胞表位和细胞表位组合物 |
| GB201511191D0 (en) * | 2015-06-25 | 2015-08-12 | Immatics Biotechnologies Gmbh | T-cell epitopes for the immunotherapy of myeloma |
| CN108137661B (zh) * | 2015-09-03 | 2021-07-27 | 香港大学 | 用于在乳腺癌患者中预测他莫昔芬响应的单克隆抗体 |
| US11209439B2 (en) | 2015-09-24 | 2021-12-28 | Mayo Foundation For Medical Education And Research | Identification of immunoglobulin free light chains by mass spectrometry |
| CN105296613A (zh) * | 2015-09-24 | 2016-02-03 | 郑州市职业病防治院 | 一种人TERF1基因rs3863242位点多态性检测技术 |
| US11371099B2 (en) | 2015-11-30 | 2022-06-28 | Mayo Foundation For Medical Education And Research | HEATR1 as a marker for chemoresistance |
| CN105785013A (zh) * | 2016-04-21 | 2016-07-20 | 卢连伟 | 一种辅助检测胰腺癌的胶体金免疫层析试纸及其制备方法 |
| GB201608192D0 (en) * | 2016-05-10 | 2016-06-22 | Immunovia Ab | Method, array and use thereof |
| JP7075125B2 (ja) * | 2016-05-25 | 2022-05-25 | イマティクス バイオテクノロジーズ ゲーエムベーハー | 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ |
| CA3030427A1 (en) | 2016-07-13 | 2018-01-18 | President And Fellows Of Harvard College | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same |
| JP7274214B2 (ja) | 2016-08-02 | 2023-05-16 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 免疫応答を調節するための生体材料 |
| WO2018049001A1 (en) | 2016-09-07 | 2018-03-15 | Mayo Foundation For Medical Education And Research | Identification and monitoring of cleaved immunoglobulins by molecular mass |
| CN107655985B (zh) * | 2017-08-25 | 2020-05-26 | 南京农业大学 | 一种基于lc-ms-ms技术的体内蛋白质营养的评价方法 |
| US11946937B2 (en) | 2017-09-13 | 2024-04-02 | Mayo Foundation For Medical Education And Research | Identification and monitoring of apoptosis inhibitor of macrophage |
| WO2019055632A1 (en) | 2017-09-13 | 2019-03-21 | Mayo Foundation For Medical Education And Research | IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN CHAINS J |
| CA3092292A1 (en) * | 2018-04-03 | 2019-10-10 | Creatics Llc | Methods for cancer detection by evaluation of glycan-binding patterns of immunoglobulins in gastrointestinal lavage fluid samples |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| EP3873528A4 (en) * | 2018-10-29 | 2022-08-10 | The Johns Hopkins University | Rasopathy treatment |
| WO2020223646A1 (en) * | 2019-05-02 | 2020-11-05 | Creatics Llc | Methods for cancer detection by evaluation of alpha-1-antitrypsin (aat) and chymotrypsin-like elastase in gastrointestinal lavage fluid samples |
| KR102798031B1 (ko) * | 2019-06-24 | 2025-04-17 | 우르테스테 에스.에이. | 새로운 췌장암 진단 마커 |
| WO2021076036A1 (en) * | 2019-10-18 | 2021-04-22 | Reccan Diagnostics Ab | Apparatuses and methods for detection of pancreatic cancer |
| CN115667938B (zh) | 2020-05-26 | 2025-08-08 | 豪夫迈·罗氏有限公司 | 用于针对定量因子-定性因子比率校验来校准客户质谱仪器的计算机实现方法 |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| KR102448586B1 (ko) * | 2020-10-08 | 2022-09-27 | 가톨릭대학교 산학협력단 | 췌장암 환자의 항암제 치료 반응성 예측용 마커 |
| EP4259201A4 (en) * | 2020-12-08 | 2025-03-19 | Memorial Sloan Kettering Cancer Center | Antibodies to galectin-3 and methods of use thereof |
| CN112461915B (zh) * | 2020-12-08 | 2024-07-12 | 杭州汇健科技有限公司 | 一种与药物敏感相关的特征分子筛选、药敏程度检测、细胞亚型检测的方法 |
| CA3202255A1 (en) | 2020-12-21 | 2022-06-30 | Hayley WARSINSKE | Markers for the early detection of colon cell proliferative disorders |
| EP4291898A1 (en) * | 2021-02-12 | 2023-12-20 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Method for prognosis and treating a patient suffering from cancer |
| US20240201166A1 (en) * | 2021-04-11 | 2024-06-20 | Vikas Khurana | Diagnosis and treatment of congestive colon failure (ccf) |
| AU2022291370A1 (en) * | 2021-06-07 | 2024-01-04 | Flagship Pioneering Innovations Vii, Llc | Compositions and methods for targeted delivery of therapeutic agents |
| CA3232274A1 (en) * | 2021-09-20 | 2023-03-23 | Jose P. Zevallos | Drain fluid for diagnostics |
| US12152280B2 (en) | 2021-09-20 | 2024-11-26 | Droplet Biosciences, Inc. | Drain fluid for diagnostics |
| US12416626B2 (en) * | 2022-07-22 | 2025-09-16 | Droplet Biosciences, Inc. | Methods for evaluating candidate therapy efficacy based on changes in lymphatic fluid biomarkers |
| WO2024086298A2 (en) * | 2022-10-20 | 2024-04-25 | The Johns Hopkins University | Hla class i and class ii-restricted t-cell epitopes in pancreatic cancer tissues and uses thereof |
| WO2024206856A2 (en) * | 2023-03-30 | 2024-10-03 | Thomas Jefferson University | Dna-dependent synthesis of rna by dna polymerase theta variants |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE28937T1 (de) * | 1982-08-09 | 1987-08-15 | Centocor Inc | Immunotest fuer kohlehydrat-antigen-determinant. |
| JPH0673470B2 (ja) * | 1986-07-15 | 1994-09-21 | 協和醗酵工業株式会社 | 抗ヒト胃癌単クロ−ン性抗体amc−462 |
| US5359681A (en) | 1993-01-11 | 1994-10-25 | University Of Washington | Fiber optic sensor and methods and apparatus relating thereto |
| US6924153B1 (en) | 1997-03-06 | 2005-08-02 | Quidel Corporation | Quantitative lateral flow assays and devices |
| JPH11225800A (ja) * | 1998-02-10 | 1999-08-24 | Kureha Chem Ind Co Ltd | 体液を用いた癌検出方法及びキット |
| US6447763B1 (en) * | 1998-06-12 | 2002-09-10 | Ian L. Gordon | Method and system for production and collection of lavage induced stool (LIS) for chemical and biologic tests of cells |
| EP1298205A4 (en) * | 2000-07-03 | 2004-06-16 | Mochida Pharm Co Ltd | NEW LIPASE |
| WO2003014298A2 (en) * | 2001-08-03 | 2003-02-20 | Origene Technologies, Inc. | Full-length prostate selective polynucleotides and polypeptides |
| US7291324B2 (en) * | 2002-10-22 | 2007-11-06 | Braintree Laboratories Inc. | Method of bowel cleansing |
| AU2003294828A1 (en) * | 2002-12-17 | 2004-07-09 | Sinogenomax Co. Ltd. Chinese National Human Genomecenter | Specific markers for pancreatic cancer |
| JP4733644B2 (ja) * | 2003-11-26 | 2011-07-27 | ダナ−ファーバー キャンサー インスティテュート インク. | 膵臓腺癌の動物モデルおよびその使用 |
| DE602005013670D1 (de) | 2004-05-21 | 2009-05-14 | Inst Systems Biology | Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen |
| JP2009528507A (ja) | 2006-03-02 | 2009-08-06 | オンコセラピー・サイエンス株式会社 | Reg4タンパク質を用いて膵癌を診断する方法 |
| EP2255198A4 (en) * | 2008-02-15 | 2011-05-25 | Mayo Foundation | DETECTION OF NEOPLASM |
| US20090258090A1 (en) | 2008-04-11 | 2009-10-15 | Braintree Laboratories, Inc. | Colon cleansing solution |
| WO2010127782A1 (en) * | 2009-05-04 | 2010-11-11 | Roche Diagnostics Gmbh | Use of dppiv/seprase as a marker for cancer |
| WO2011027311A2 (en) * | 2009-09-03 | 2011-03-10 | Koninklijke Philips Electronics N.V. | Novel tumor markers |
| US9075059B2 (en) * | 2009-11-05 | 2015-07-07 | University Of Virginia Patent Foundation | Compositions and methods for detecting plectin-1 as a biomarker for cancer |
| CN105785003B (zh) * | 2010-06-01 | 2018-09-07 | 梅坦诺米克斯保健有限公司 | 用于在受试者中诊断胰腺癌的工具和方法 |
| KR101857462B1 (ko) * | 2010-08-13 | 2018-05-14 | 소마로직, 인크. | 췌장암 바이오마커 및 그것의 용도 |
| WO2012092529A2 (en) * | 2010-12-29 | 2012-07-05 | Expression Pathology, Inc. | Protein biomarkers of recurrent breast cancer |
| JP5984795B2 (ja) * | 2011-04-05 | 2016-09-06 | オリンパス株式会社 | 膵疾患を検出するためのデータを収集する方法 |
| US10226238B2 (en) * | 2011-09-12 | 2019-03-12 | Creatics Llc | Non-invasive methods of detecting target molecules |
-
2014
- 2014-03-13 AU AU2014243704A patent/AU2014243704A1/en not_active Abandoned
- 2014-03-13 WO PCT/US2014/026857 patent/WO2014160499A2/en not_active Ceased
- 2014-03-13 US US14/773,969 patent/US20160033511A1/en not_active Abandoned
- 2014-03-13 HK HK16102515.4A patent/HK1214652A1/zh unknown
- 2014-03-13 EP EP14729753.5A patent/EP2972375A2/en not_active Withdrawn
- 2014-03-13 JP JP2016502266A patent/JP6646571B2/ja not_active Expired - Fee Related
- 2014-03-13 CA CA2902841A patent/CA2902841A1/en not_active Abandoned
-
2018
- 2018-07-26 US US16/046,606 patent/US20190234951A1/en not_active Abandoned
-
2020
- 2020-01-09 JP JP2020001856A patent/JP7109008B2/ja active Active
- 2020-03-23 AU AU2020202066A patent/AU2020202066B2/en not_active Ceased
-
2021
- 2021-07-20 US US17/380,219 patent/US20220128563A1/en not_active Abandoned
-
2022
- 2022-07-07 JP JP2022109693A patent/JP2022141755A/ja not_active Withdrawn
- 2022-08-31 AU AU2022224782A patent/AU2022224782A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP7109008B2 (ja) | 2022-08-10 |
| US20220128563A1 (en) | 2022-04-28 |
| US20190234951A1 (en) | 2019-08-01 |
| AU2020202066B2 (en) | 2022-06-02 |
| EP2972375A2 (en) | 2016-01-20 |
| JP2020091295A (ja) | 2020-06-11 |
| HK1214652A1 (zh) | 2016-07-29 |
| CA2902841A1 (en) | 2014-10-02 |
| WO2014160499A2 (en) | 2014-10-02 |
| WO2014160499A3 (en) | 2015-01-29 |
| JP2022141755A (ja) | 2022-09-29 |
| AU2020202066A1 (en) | 2020-04-09 |
| US20160033511A1 (en) | 2016-02-04 |
| AU2022224782A1 (en) | 2022-09-22 |
| JP6646571B2 (ja) | 2020-02-14 |
| JP2016519285A (ja) | 2016-06-30 |
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