HK1214652A1 - 用於检测胰腺癌的方法和组合物 - Google Patents

用於检测胰腺癌的方法和组合物 Download PDF

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Publication number
HK1214652A1
HK1214652A1 HK16102515.4A HK16102515A HK1214652A1 HK 1214652 A1 HK1214652 A1 HK 1214652A1 HK 16102515 A HK16102515 A HK 16102515A HK 1214652 A1 HK1214652 A1 HK 1214652A1
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HK
Hong Kong
Prior art keywords
pancreatic cancer
methods
compositions
detecting pancreatic
detecting
Prior art date
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HK16102515.4A
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English (en)
Chinese (zh)
Inventor
．潘內爾
L．K．潘内尔
．羅克
J.罗克
Original Assignee
克里蒂科斯有限责任公司
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Application filed by 克里蒂科斯有限责任公司 filed Critical 克里蒂科斯有限责任公司
Publication of HK1214652A1 publication Critical patent/HK1214652A1/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16102515.4A 2013-03-13 2014-03-13 用於检测胰腺癌的方法和组合物 HK1214652A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361780574P 2013-03-13 2013-03-13
US61/780574 2013-03-13
PCT/US2014/026857 WO2014160499A2 (en) 2013-03-13 2014-03-13 Methods and compositions for detecting pancreatic cancer

Publications (1)

Publication Number Publication Date
HK1214652A1 true HK1214652A1 (zh) 2016-07-29

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Application Number Title Priority Date Filing Date
HK16102515.4A HK1214652A1 (zh) 2013-03-13 2014-03-13 用於检测胰腺癌的方法和组合物

Country Status (7)

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US (3) US20160033511A1 (enExample)
EP (1) EP2972375A2 (enExample)
JP (3) JP6646571B2 (enExample)
AU (3) AU2014243704A1 (enExample)
CA (1) CA2902841A1 (enExample)
HK (1) HK1214652A1 (enExample)
WO (1) WO2014160499A2 (enExample)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2347774B1 (en) 2005-12-13 2017-07-26 The President and Fellows of Harvard College Scaffolds for cell transplantation
ES2442919T3 (es) 2007-03-27 2014-02-14 Immunovia Ab Firma/marcadores de proteínas para la detección de adenocarcinoma
AU2011311904B2 (en) 2010-10-06 2016-02-25 President And Fellows Of Harvard College Injectable, pore-forming hydrogels for materials-based cell therapies
US9675561B2 (en) 2011-04-28 2017-06-13 President And Fellows Of Harvard College Injectable cryogel vaccine devices and methods of use thereof
CA2848162C (en) 2011-09-12 2023-03-14 Creatics Llc Non-invasive methods of detecting target molecules
EP2836512B1 (en) 2012-04-11 2018-10-24 F.Hoffmann-La Roche Ag Improved antibody light chains
PT2838515T (pt) 2012-04-16 2020-02-25 Harvard College Composições de sílica mesoporosa para modular respostas imunológicas
WO2014004931A1 (en) 2012-06-27 2014-01-03 Berg Pharma Llc Use of markers in the diagnosis and treatment of prostate cancer
HRP20171269T1 (hr) 2013-03-15 2017-11-03 Shire Viropharma Incorporated C1-inh pripravci za upotrebu za prevenciju i liječenje nasljednog angioedema (hae)
WO2014205374A1 (en) * 2013-06-20 2014-12-24 The Trustees Of The University Of Pennsylvania Methods for diagnosing pancreatic cancer
ES2861600T3 (es) 2014-04-04 2021-10-06 Mayo Found Medical Education & Res Isotipaje de inmunoglobulinas usando masa molecular precisa
JP7348708B2 (ja) 2014-04-30 2023-09-21 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 組み合わせワクチン装置および癌細胞を殺滅する方法
CN106461678A (zh) * 2014-05-26 2017-02-22 奥林巴斯株式会社 胰腺癌判定方法
KR20160045547A (ko) * 2014-10-17 2016-04-27 에스케이텔레콤 주식회사 췌장암 진단용 조성물 및 이를 이용한 췌장암 진단방법
KR102657306B1 (ko) 2014-12-08 2024-04-12 버그 엘엘씨 전립선암의 진단 및 치료에서 필라민을 포함하는 마커의 용도
WO2016100735A1 (en) 2014-12-19 2016-06-23 Roche Nimblegen, Inc. Microbial transglutaminases, substrates therefor and methods for the use thereof
US11054425B2 (en) 2014-12-19 2021-07-06 Roche Sequencing Solutions, Inc. System and method for identification and characterization of transglutaminase species
EP3233883B1 (en) * 2014-12-19 2019-10-16 F.Hoffmann-La Roche Ag Identification of transglutaminase substrates and uses therefor
HK1247861A1 (zh) 2015-01-30 2018-10-05 President And Fellows Of Harvard College 用於癌症治疗的肿瘤周围和肿瘤内部材料
US20160271120A1 (en) * 2015-03-17 2016-09-22 Oakdene Holdings Llc Pharmaceutical composition for cleansing of the gastrointestinal tract
GB201505654D0 (en) * 2015-04-01 2015-05-13 Nordic Bioscience As Immunoassay for collagen type VI sequence
US20180306788A1 (en) * 2015-04-07 2018-10-25 President And Fellows Of Harvard College Compositions and methods for modulating hydroxylation of acc2 by phd3
JP7094533B2 (ja) 2015-04-10 2022-07-04 プレジデント アンド フェローズ オブ ハーバード カレッジ 免疫細胞捕捉デバイスおよびその製造および使用方法
CA2980495A1 (en) * 2015-04-20 2016-10-27 Consejo Superior De Investigaciones Cientificas Agents binding specifically to human cadherin-17, human cadherin-5, human cadherin-6 and human cadherin-20 rgd motif
HK1254866A1 (zh) 2015-06-25 2019-07-26 Immatics Biotechnologies Gmbh 用於骨髓瘤和其他癌症免疫治疗的新型细胞表位和细胞表位组合物
GB201511191D0 (en) * 2015-06-25 2015-08-12 Immatics Biotechnologies Gmbh T-cell epitopes for the immunotherapy of myeloma
CN108137661B (zh) * 2015-09-03 2021-07-27 香港大学 用于在乳腺癌患者中预测他莫昔芬响应的单克隆抗体
CN105296613A (zh) * 2015-09-24 2016-02-03 郑州市职业病防治院 一种人TERF1基因rs3863242位点多态性检测技术
US11209439B2 (en) 2015-09-24 2021-12-28 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
WO2017095632A1 (en) * 2015-11-30 2017-06-08 Mayo Foundation For Medical Education And Research Heatr1 as a marker for chemoresistance
CN105785013A (zh) * 2016-04-21 2016-07-20 卢连伟 一种辅助检测胰腺癌的胶体金免疫层析试纸及其制备方法
GB201608192D0 (en) * 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
JP7075125B2 (ja) * 2016-05-25 2022-05-25 イマティクス バイオテクノロジーズ ゲーエムベーハー 標的としてのおよび胆嚢がんおよび胆管がんおよびその他のがんに対する免疫療法で使用するための新規ペプチド、ペプチド組み合わせ
AU2017295704B2 (en) 2016-07-13 2023-07-13 President And Fellows Of Harvard College Antigen-presenting cell-mimetic scaffolds and methods for making and using the same
WO2018026884A1 (en) 2016-08-02 2018-02-08 President And Fellows Of Harvard College Biomaterials for modulating immune responses
AU2017325022B2 (en) 2016-09-07 2022-10-13 Mayo Foundation For Medical Education And Research Identification and monitoring of cleaved immunoglobulins by molecular mass
CN107655985B (zh) * 2017-08-25 2020-05-26 南京农业大学 一种基于lc-ms-ms技术的体内蛋白质营养的评价方法
EP3681528B1 (en) 2017-09-13 2025-07-23 Mayo Foundation for Medical Education and Research Identification and monitoring of apoptosis inhibitor of macrophage
EP3681907A4 (en) 2017-09-13 2021-07-07 Mayo Foundation for Medical Education and Research IDENTIFICATION AND MONITORING OF IMMUNOGLOBULIN J-CHAINS
EP3775911A1 (en) * 2018-04-03 2021-02-17 Creatics LLC Methods for cancer detection by evaluation of glycan-binding patterns of immunoglobulins in gastrointestinal lavage fluid samples
WO2020061129A1 (en) 2018-09-19 2020-03-26 President And Fellows Of Harvard College Compositions and methods for labeling and modulation of cells in vitro and in vivo
US20210395736A1 (en) * 2018-10-29 2021-12-23 The Johns Hopkins University Rasopathy treatment
WO2020223646A1 (en) * 2019-05-02 2020-11-05 Creatics Llc Methods for cancer detection by evaluation of alpha-1-antitrypsin (aat) and chymotrypsin-like elastase in gastrointestinal lavage fluid samples
MX2021016095A (es) * 2019-06-24 2022-02-03 Urteste S A Nuevo marcador de diagnostico para cancer pancreatico.
EP4045912A1 (en) * 2019-10-18 2022-08-24 Reccan Diagnostics AB Apparatuses and methods for detection of pancreatic cancer
WO2021239692A1 (en) 2020-05-26 2021-12-02 F. Hoffmann-La Roche Ag Computer implemented method for calibrating a customer mass spectrometry instrument for quantifier-qualifier-ratio check
GB202010970D0 (en) 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
KR102448586B1 (ko) * 2020-10-08 2022-09-27 가톨릭대학교 산학협력단 췌장암 환자의 항암제 치료 반응성 예측용 마커
WO2022125482A1 (en) * 2020-12-08 2022-06-16 Memorial Sloan Kettering Cancer Center Antibodies to galectin-3 and methods of use thereof
CN112461915B (zh) * 2020-12-08 2024-07-12 杭州汇健科技有限公司 一种与药物敏感相关的特征分子筛选、药敏程度检测、细胞亚型检测的方法
CN117083525A (zh) 2020-12-21 2023-11-17 福瑞诺姆控股公司 用于结肠细胞增殖性病症的早期检测的标志物
US20240229154A9 (en) * 2021-02-12 2024-07-11 Institut National de la Santé et de la Recherche Médicale Method for prognosis and treating a patient suffering from cancer
WO2022221173A1 (en) * 2021-04-11 2022-10-20 Khurana Vikas Device and process for trapping and compressing organisms
WO2022261136A1 (en) * 2021-06-07 2022-12-15 Flagship Pioneering Innovations Vii, Llc Compositions and methods for targeted delivery of therapeutic agents
CA3232274A1 (en) * 2021-09-20 2023-03-23 Jose P. Zevallos Drain fluid for diagnostics
US12152280B2 (en) 2021-09-20 2024-11-26 Droplet Biosciences, Inc. Drain fluid for diagnostics
US12416626B2 (en) * 2022-07-22 2025-09-16 Droplet Biosciences, Inc. Methods for evaluating candidate therapy efficacy based on changes in lymphatic fluid biomarkers
WO2024086298A2 (en) * 2022-10-20 2024-04-25 The Johns Hopkins University Hla class i and class ii-restricted t-cell epitopes in pancreatic cancer tissues and uses thereof
WO2024206856A2 (en) * 2023-03-30 2024-10-03 Thomas Jefferson University Dna-dependent synthesis of rna by dna polymerase theta variants

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114818B1 (en) * 1982-08-09 1987-08-12 Centocor, Inc. Immunoassay for carbohydrate antigenic determinant
JPH0673470B2 (ja) * 1986-07-15 1994-09-21 協和醗酵工業株式会社 抗ヒト胃癌単クロ−ン性抗体ａｍｃ−４６２
US5359681A (en) 1993-01-11 1994-10-25 University Of Washington Fiber optic sensor and methods and apparatus relating thereto
US6924153B1 (en) 1997-03-06 2005-08-02 Quidel Corporation Quantitative lateral flow assays and devices
JPH11225800A (ja) * 1998-02-10 1999-08-24 Kureha Chem Ind Co Ltd 体液を用いた癌検出方法及びキット
US6447763B1 (en) * 1998-06-12 2002-09-10 Ian L. Gordon Method and system for production and collection of lavage induced stool (LIS) for chemical and biologic tests of cells
EP1298205A4 (en) * 2000-07-03 2004-06-16 Mochida Pharm Co Ltd NEW LIPASE
US20050120393A1 (en) * 2001-08-03 2005-06-02 Origene Technologies, Inc. Full-length prostate selective polynucleotides and polypeptides
US7291324B2 (en) * 2002-10-22 2007-11-06 Braintree Laboratories Inc. Method of bowel cleansing
US20040219572A1 (en) * 2002-12-17 2004-11-04 Jie Chen Specific markers for pancreatic cancer
WO2005053512A2 (en) * 2003-11-26 2005-06-16 Dana-Farber Cancer Institute, Inc. Animal models of pancreatic adenocarcinoma and uses therefor
DK1766412T3 (da) 2004-05-21 2009-05-25 Inst Systems Biology Sammensætninger og fremgangsmåder til kvantificering af serumglycoproteiner
KR20090003308A (ko) 2006-03-02 2009-01-09 온코세라피 사이언스 가부시키가이샤 Ｒｅｇ４ 단백질을 이용한 췌장암 진단 방법
EP2255198A4 (en) * 2008-02-15 2011-05-25 Mayo Foundation DETECTION OF NEOPLASM
US20090258090A1 (en) 2008-04-11 2009-10-15 Braintree Laboratories, Inc. Colon cleansing solution
JP5312684B2 (ja) * 2009-05-04 2013-10-09 エフ．ホフマン−ラ ロシュ アーゲー 癌のマーカーとしてのｄｐｐｉｖ／セプラーゼの使用
WO2011027311A2 (en) * 2009-09-03 2011-03-10 Koninklijke Philips Electronics N.V. Novel tumor markers
JP2013510094A (ja) * 2009-11-05 2013-03-21 ユニバーシティ オブ バージニア パテント ファウンデーション がんのバイオマーカーとしてプレクチン−１を検出するための組成物および方法
EP3355057A3 (en) * 2010-06-01 2018-12-12 Metanomics Health GmbH Means and methods for diagnosing pancreatic cancer in a subject
MX350533B (es) * 2010-08-13 2017-09-08 Somalogic Inc Biomarcadores de cancer pancreatico y usos de los mismos.
EP2659272A4 (en) * 2010-12-29 2015-07-22 Expression Pathology Inc PROTEIN BIOMARKERS FOR RECIPIENT BREAST CANCER
JP5984795B2 (ja) * 2011-04-05 2016-09-06 オリンパス株式会社 膵疾患を検出するためのデータを収集する方法
CA2848162C (en) * 2011-09-12 2023-03-14 Creatics Llc Non-invasive methods of detecting target molecules

Also Published As

Publication number Publication date
CA2902841A1 (en) 2014-10-02
US20160033511A1 (en) 2016-02-04
AU2020202066B2 (en) 2022-06-02
JP2022141755A (ja) 2022-09-29
JP2016519285A (ja) 2016-06-30
AU2020202066A1 (en) 2020-04-09
JP6646571B2 (ja) 2020-02-14
AU2022224782A1 (en) 2022-09-22
US20190234951A1 (en) 2019-08-01
US20220128563A1 (en) 2022-04-28
AU2014243704A1 (en) 2015-09-10
JP7109008B2 (ja) 2022-08-10
EP2972375A2 (en) 2016-01-20
JP2020091295A (ja) 2020-06-11
WO2014160499A3 (en) 2015-01-29
WO2014160499A2 (en) 2014-10-02

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