DE602005013670D1 - Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen - Google Patents
Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinenInfo
- Publication number
- DE602005013670D1 DE602005013670D1 DE602005013670T DE602005013670T DE602005013670D1 DE 602005013670 D1 DE602005013670 D1 DE 602005013670D1 DE 602005013670 T DE602005013670 T DE 602005013670T DE 602005013670 T DE602005013670 T DE 602005013670T DE 602005013670 D1 DE602005013670 D1 DE 602005013670D1
- Authority
- DE
- Germany
- Prior art keywords
- compositions
- quantitating
- serum glycoproteins
- human serum
- plasma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57359304P | 2004-05-21 | 2004-05-21 | |
PCT/US2005/017842 WO2005114221A2 (en) | 2004-05-21 | 2005-05-20 | Compositions and methods for quantification of serum glycoproteins |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005013670D1 true DE602005013670D1 (de) | 2009-05-14 |
Family
ID=35429005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005013670T Active DE602005013670D1 (de) | 2004-05-21 | 2005-05-20 | Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen |
Country Status (6)
Country | Link |
---|---|
US (2) | US20060141528A1 (de) |
EP (4) | EP2302393A1 (de) |
AT (1) | ATE427499T1 (de) |
DE (1) | DE602005013670D1 (de) |
DK (1) | DK1766412T3 (de) |
WO (1) | WO2005114221A2 (de) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE344456T1 (de) * | 2000-05-05 | 2006-11-15 | Purdue Research Foundation | Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen |
AU2002341862C1 (en) * | 2001-09-27 | 2009-01-29 | Purdue Research Foundation | Controlling isotope effects during fractionation of analytes |
DE10254601A1 (de) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
US7384754B2 (en) * | 2003-10-31 | 2008-06-10 | Agilent Technologies, Inc. | Enrichment and tagging of glycosylated proteins |
DE102004024617A1 (de) | 2004-05-18 | 2005-12-29 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
US20070099251A1 (en) * | 2005-10-17 | 2007-05-03 | Institute For Systems Biology | Tissue-and serum-derived glycoproteins and methods of their use |
EP1790664A1 (de) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoklonale Antikörper gegen Claudin-18 zur Behandlung von Krebs |
EP2057465A4 (de) * | 2006-08-09 | 2010-04-21 | Homestead Clinical Corp | Organspezifische proteine und anwendungsverfahren dafür |
US7879799B2 (en) * | 2006-08-10 | 2011-02-01 | Institute For Systems Biology | Methods for characterizing glycoproteins and generating antibodies for same |
CA2689296C (en) | 2007-01-10 | 2015-11-17 | Purdue Research Foundation | Polypeptide inhibitors of hsp27 kinase and uses therefor |
US8741849B2 (en) | 2007-01-10 | 2014-06-03 | Purdue Research Foundation | Kinase inhibitors and uses thereof |
WO2008134526A2 (en) * | 2007-04-27 | 2008-11-06 | University Of Florida Research Foundation Inc. | Glycoprotein profiling of bladder cancer |
WO2008151238A1 (en) * | 2007-06-04 | 2008-12-11 | The Johns Hopkins University | Biomarkers for prostate cancer |
JP2010530962A (ja) * | 2007-06-12 | 2010-09-16 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 血漿においてタンパク質を検出する方法 |
US20100168382A1 (en) * | 2007-06-12 | 2010-07-01 | Vladimir Berezin | Neuroplastin derived peptides |
US8628912B2 (en) * | 2007-07-03 | 2014-01-14 | Northeastern University | Biomarkers for diabetes, obesity, and/or hypertension |
WO2009014450A1 (en) * | 2007-07-24 | 2009-01-29 | Sanare As | Novel peptides with anti-tumor activity |
EP2245055A2 (de) * | 2008-01-31 | 2010-11-03 | Compugen Ltd. | Polypeptide und polynukleotide und deren verwendung als arzneimittel-target zur herstellung von arzneimitteln und biologika |
CA2744104C (en) | 2008-12-10 | 2017-07-18 | Purdue Research Foundation | Cell-permeant peptide-based inhibitor of kinases |
EP2427844A4 (de) * | 2009-05-08 | 2016-11-02 | Thermo Finnigan Llc | Verfahren und systeme zur abstimmung von produkten und vorläuferionen |
CN102695716B (zh) * | 2009-07-14 | 2016-03-02 | 独立行政法人产业技术综合研究所 | 肝病病情指标糖链标记物 |
WO2011017132A2 (en) | 2009-07-27 | 2011-02-10 | Purdue Research, Foundation | Mk2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration |
WO2011143386A1 (en) * | 2010-05-14 | 2011-11-17 | Dh Technologies Development Pte. Ltd. | Systems and methods for calculating protein confidence values |
DK2632479T3 (en) * | 2010-10-27 | 2017-08-07 | Baxalta GmbH | FVIII PEPTIDES FOR IMMUNT TOLERANCE INDUCTION AND IMMUNODIAGNOSTICS |
US9403889B2 (en) | 2010-11-29 | 2016-08-02 | Integrated Diagnostics, Inc. | Diagnostic lung cancer panel and methods for its use |
US8772043B2 (en) | 2010-12-23 | 2014-07-08 | Pioneer Hi Bred International Inc | Universal peptide tags for transgene polypeptide analysis by mass spectrometry |
CA2835806A1 (en) * | 2011-05-13 | 2012-11-22 | King's College London | Methods and compositions relating to platelet sensitivity |
EP2715367A2 (de) | 2011-06-03 | 2014-04-09 | University of South Alabama | Verfahren und zusammensetzungen zum nachweis von endometrium- oder ovarialkrebs |
US9506167B2 (en) | 2011-07-29 | 2016-11-29 | Ginkgo Bioworks, Inc. | Methods and systems for cell state quantification |
JP2014526682A (ja) | 2011-09-12 | 2014-10-06 | クリエイティクス エルエルシー | 標的分子を検出する非侵襲的方法 |
CN103134874B (zh) * | 2011-12-01 | 2015-05-20 | 成都康弘生物科技有限公司 | 一种测定蛋白中糖基的方法 |
JP6082026B2 (ja) | 2011-12-21 | 2017-02-15 | インテグレイティド ダイアグノスティクス,インコーポレイティド | 肺癌診断用の組成物、方法及びキット |
US9304137B2 (en) | 2011-12-21 | 2016-04-05 | Integrated Diagnostics, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
US11913957B2 (en) | 2011-12-21 | 2024-02-27 | Biodesix, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
AU2013208293B2 (en) | 2012-01-09 | 2017-08-10 | Serpin Pharma, Llc | Peptides and methods of using same |
US9452218B2 (en) | 2012-03-09 | 2016-09-27 | Purdue Research Foundation | Compositions and methods for delivery of kinase inhibiting peptides |
WO2013167153A1 (en) | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
JP6296615B2 (ja) * | 2012-11-06 | 2018-03-20 | 国立大学法人 宮崎大学 | 新規ペプチドおよびその用途 |
WO2014100717A2 (en) | 2012-12-21 | 2014-06-26 | Integrated Diagnostics, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
WO2014160499A2 (en) | 2013-03-13 | 2014-10-02 | Creatics Llc | Methods and compositions for detecting pancreatic cancer |
GB201310150D0 (en) * | 2013-06-07 | 2013-07-24 | Electrophoretics Ltd | Methods and compositions relating to alzheimer's disease |
US9297805B2 (en) | 2013-07-26 | 2016-03-29 | Integrated Diagnostics, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
US9594085B2 (en) | 2014-02-03 | 2017-03-14 | Integrated Diagnostics, Inc. | Integrated quantification method for protein measurements in clinical proteomics |
US10000533B2 (en) | 2014-06-20 | 2018-06-19 | Immatics Biotechnologies Gmbh | Immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemia (CLL) |
GB201411037D0 (en) * | 2014-06-20 | 2014-08-06 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL) |
WO2016038608A1 (en) * | 2014-09-08 | 2016-03-17 | Carmel Haifa University Economic Corporation Ltd. | Peptides derived from angiotensin receptor and use thereof |
US10035823B2 (en) | 2014-09-29 | 2018-07-31 | The Regents Of The University Of California | Compositions for expanding regulatory T cells (TREG), and treating autoimmune and inflammatory diseases and conditions |
GB201505305D0 (en) * | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
CN109265517B (zh) | 2015-03-27 | 2024-05-10 | 伊玛提克斯生物技术有限公司 | 用于各种肿瘤免疫治疗的肽和肽组合物 |
CA2996975C (en) | 2015-08-28 | 2022-02-15 | Serpin Pharma, Llc | Methods for treatment of diseases |
GB201520568D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd | Peptides |
GB201520550D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520559D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
CN110114680A (zh) | 2016-05-05 | 2019-08-09 | 佰欧迪塞克斯公司 | 用于诊断肺癌的组合物、方法和试剂盒 |
US9960027B2 (en) | 2016-05-25 | 2018-05-01 | Thermo Finnigan Llc | Analyzing a complex sample by MS/MS using isotopically-labeled standards |
MY202410A (en) * | 2017-09-01 | 2024-04-27 | Venn Biosciences Corp | Identification and use of glycopeptides as biomarkers for diagnosis and treatment monitoring |
ES2710321A1 (es) * | 2017-10-20 | 2019-04-24 | Consejo Superior Investigacion | Adn polimerasas independientes de cebador y su uso para la sintesis de adn |
WO2020223646A1 (en) | 2019-05-02 | 2020-11-05 | Creatics Llc | Methods for cancer detection by evaluation of alpha-1-antitrypsin (aat) and chymotrypsin-like elastase in gastrointestinal lavage fluid samples |
CN110563844A (zh) * | 2019-09-04 | 2019-12-13 | 华中农业大学 | 一种抗犬白介素31受体的多克隆抗体及其应用 |
WO2021050510A1 (en) * | 2019-09-09 | 2021-03-18 | The Wistar Institute Of Anatomy And Biology | Engineered peptide and peptide mimetic compositions and methods |
EP4329793A2 (de) * | 2021-04-29 | 2024-03-06 | Seer, Inc. | Peptiddekorierte nanopartikel zur anreicherung spezifischer proteinuntermengen |
CN113480629B (zh) * | 2021-06-16 | 2022-08-19 | 复旦大学 | 区分肝癌和正常人的末端唾液酸化异构糖肽标志物及其筛查方法 |
US11542340B1 (en) | 2021-10-29 | 2023-01-03 | Biodesix, Inc. | Antibodies targeting pulmonary nodule specific biomarkers and uses thereof |
NL2030990B1 (en) * | 2022-02-17 | 2023-09-01 | Academisch Ziekenhuis Leiden | T cell receptors directed against jchain and uses thereof |
WO2024086826A2 (en) * | 2022-10-21 | 2024-04-25 | Quantum-Si Incorporated | Polypeptidyl linkers |
CN117969642A (zh) * | 2024-04-02 | 2024-05-03 | 浙江大学 | 一种植物n-糖链的精准相对定量分析方法及应用 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2226032B (en) * | 1988-12-16 | 1993-08-18 | Urs Heimgartner | Detection of glycoproteins |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US5079336A (en) * | 1989-06-23 | 1992-01-07 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
US5264563A (en) | 1990-08-24 | 1993-11-23 | Ixsys Inc. | Process for synthesizing oligonucleotides with random codons |
GB9112504D0 (en) * | 1991-06-11 | 1991-07-31 | Merck Sharp & Dohme | Cell line |
US5986076A (en) | 1994-05-11 | 1999-11-16 | Trustees Of Boston University | Photocleavable agents and conjugates for the detection and isolation of biomolecules |
DE69531545T2 (de) | 1994-06-23 | 2004-06-24 | Affymax Technologies N.V., Willemstad | Photolabile verbindungen und verfahren für deren verwendung |
DE69724428T3 (de) * | 1996-06-07 | 2009-07-23 | Poniard Pharmaceuticals, Inc., Seattle | Humanisierte antikörper die an das gleiche antigen wie antikörper nr-lu-13 binden und deren verwendung in "pretargeting" verfahren |
CA2272407C (en) * | 1996-12-10 | 2012-07-31 | Sloan-Kettering Institute For Cancer Research | Method and compositions for stimulation of an immune response to a differentiation antigen stimulated by an altered differentiation antigen |
US6046013A (en) * | 1997-08-01 | 2000-04-04 | Gti | Process for identifying specific antibodies associated with HLA |
ATE253126T1 (de) | 1998-08-25 | 2003-11-15 | Univ Washington | Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen |
US6407210B1 (en) * | 1998-11-09 | 2002-06-18 | University Of Utah Research Foundation | Nematode neuromuscular junction GABA receptors and methods related thereto |
JP2003518364A (ja) * | 1999-05-28 | 2003-06-10 | ルードヴィッヒ インスティテュート フォー キャンサー リサーチ | 乳癌、胃癌および前立腺癌関連抗原ならびにそれらの使用 |
JP4048115B2 (ja) | 2000-12-26 | 2008-02-13 | ザ インスティチュート フォー システムズ バイオロジー | 迅速かつ定量的なプロテオーム解析および関連した方法 |
EP1435957B1 (de) * | 2001-04-30 | 2009-06-17 | Vertex Pharmaceuticals Incorporated | Inhibitoren von gsk-3 und kristallstrukturen von gsk-3beta-protein und -proteinkomplexen |
AU2002341862C1 (en) * | 2001-09-27 | 2009-01-29 | Purdue Research Foundation | Controlling isotope effects during fractionation of analytes |
WO2003102018A2 (en) * | 2002-06-03 | 2003-12-11 | The Institute For Systems Biology | Methods for quantitative proteome analysis of glycoproteins |
WO2005007677A2 (en) * | 2003-07-10 | 2005-01-27 | The Institute For Systems Biology | Affinity capture of peptides by microarray and related methods |
US7593336B2 (en) * | 2003-10-31 | 2009-09-22 | Brocade Communications Systems, Inc. | Logical ports in trunking |
US7348416B2 (en) * | 2003-11-21 | 2008-03-25 | Applera Corporation | Selective capture and enrichment of proteins expressed on the cell surface |
-
2005
- 2005-05-20 EP EP10012636A patent/EP2302393A1/de not_active Withdrawn
- 2005-05-20 EP EP09153474A patent/EP2093569A3/de not_active Withdrawn
- 2005-05-20 WO PCT/US2005/017842 patent/WO2005114221A2/en active Application Filing
- 2005-05-20 DK DK05751819T patent/DK1766412T3/da active
- 2005-05-20 US US11/134,871 patent/US20060141528A1/en not_active Abandoned
- 2005-05-20 DE DE602005013670T patent/DE602005013670D1/de active Active
- 2005-05-20 AT AT05751819T patent/ATE427499T1/de not_active IP Right Cessation
- 2005-05-20 EP EP10012637A patent/EP2302394A1/de not_active Withdrawn
- 2005-05-20 EP EP05751819A patent/EP1766412B1/de not_active Not-in-force
-
2010
- 2010-03-12 US US12/723,574 patent/US20100279382A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2005114221A2 (en) | 2005-12-01 |
EP2093569A3 (de) | 2009-11-11 |
DK1766412T3 (da) | 2009-05-25 |
ATE427499T1 (de) | 2009-04-15 |
EP2302393A1 (de) | 2011-03-30 |
EP2302394A1 (de) | 2011-03-30 |
EP1766412B1 (de) | 2009-04-01 |
EP1766412A2 (de) | 2007-03-28 |
WO2005114221A8 (en) | 2006-05-04 |
US20100279382A1 (en) | 2010-11-04 |
EP2302393A8 (de) | 2011-08-03 |
EP2093569A2 (de) | 2009-08-26 |
WO2005114221A3 (en) | 2006-12-21 |
US20060141528A1 (en) | 2006-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |