DE602005013670D1 - Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen - Google Patents

Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen

Info

Publication number
DE602005013670D1
DE602005013670D1 DE602005013670T DE602005013670T DE602005013670D1 DE 602005013670 D1 DE602005013670 D1 DE 602005013670D1 DE 602005013670 T DE602005013670 T DE 602005013670T DE 602005013670 T DE602005013670 T DE 602005013670T DE 602005013670 D1 DE602005013670 D1 DE 602005013670D1
Authority
DE
Germany
Prior art keywords
compositions
quantitating
serum glycoproteins
human serum
plasma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005013670T
Other languages
English (en)
Inventor
Rudolph H Aebersold
Hui Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute for Systems Biology
Original Assignee
Institute for Systems Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute for Systems Biology filed Critical Institute for Systems Biology
Publication of DE602005013670D1 publication Critical patent/DE602005013670D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
DE602005013670T 2004-05-21 2005-05-20 Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen Active DE602005013670D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57359304P 2004-05-21 2004-05-21
PCT/US2005/017842 WO2005114221A2 (en) 2004-05-21 2005-05-20 Compositions and methods for quantification of serum glycoproteins

Publications (1)

Publication Number Publication Date
DE602005013670D1 true DE602005013670D1 (de) 2009-05-14

Family

ID=35429005

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005013670T Active DE602005013670D1 (de) 2004-05-21 2005-05-20 Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen

Country Status (6)

Country Link
US (2) US20060141528A1 (de)
EP (4) EP2302393A1 (de)
AT (1) ATE427499T1 (de)
DE (1) DE602005013670D1 (de)
DK (1) DK1766412T3 (de)
WO (1) WO2005114221A2 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE344456T1 (de) * 2000-05-05 2006-11-15 Purdue Research Foundation Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen
AU2002341862C1 (en) * 2001-09-27 2009-01-29 Purdue Research Foundation Controlling isotope effects during fractionation of analytes
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
US7384754B2 (en) * 2003-10-31 2008-06-10 Agilent Technologies, Inc. Enrichment and tagging of glycosylated proteins
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
US20070099251A1 (en) * 2005-10-17 2007-05-03 Institute For Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
EP1790664A1 (de) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoklonale Antikörper gegen Claudin-18 zur Behandlung von Krebs
EP2057465A4 (de) * 2006-08-09 2010-04-21 Homestead Clinical Corp Organspezifische proteine und anwendungsverfahren dafür
US7879799B2 (en) * 2006-08-10 2011-02-01 Institute For Systems Biology Methods for characterizing glycoproteins and generating antibodies for same
CA2689296C (en) 2007-01-10 2015-11-17 Purdue Research Foundation Polypeptide inhibitors of hsp27 kinase and uses therefor
US8741849B2 (en) 2007-01-10 2014-06-03 Purdue Research Foundation Kinase inhibitors and uses thereof
WO2008134526A2 (en) * 2007-04-27 2008-11-06 University Of Florida Research Foundation Inc. Glycoprotein profiling of bladder cancer
WO2008151238A1 (en) * 2007-06-04 2008-12-11 The Johns Hopkins University Biomarkers for prostate cancer
JP2010530962A (ja) * 2007-06-12 2010-09-16 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 血漿においてタンパク質を検出する方法
US20100168382A1 (en) * 2007-06-12 2010-07-01 Vladimir Berezin Neuroplastin derived peptides
US8628912B2 (en) * 2007-07-03 2014-01-14 Northeastern University Biomarkers for diabetes, obesity, and/or hypertension
WO2009014450A1 (en) * 2007-07-24 2009-01-29 Sanare As Novel peptides with anti-tumor activity
EP2245055A2 (de) * 2008-01-31 2010-11-03 Compugen Ltd. Polypeptide und polynukleotide und deren verwendung als arzneimittel-target zur herstellung von arzneimitteln und biologika
CA2744104C (en) 2008-12-10 2017-07-18 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
EP2427844A4 (de) * 2009-05-08 2016-11-02 Thermo Finnigan Llc Verfahren und systeme zur abstimmung von produkten und vorläuferionen
CN102695716B (zh) * 2009-07-14 2016-03-02 独立行政法人产业技术综合研究所 肝病病情指标糖链标记物
WO2011017132A2 (en) 2009-07-27 2011-02-10 Purdue Research, Foundation Mk2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
WO2011143386A1 (en) * 2010-05-14 2011-11-17 Dh Technologies Development Pte. Ltd. Systems and methods for calculating protein confidence values
DK2632479T3 (en) * 2010-10-27 2017-08-07 Baxalta GmbH FVIII PEPTIDES FOR IMMUNT TOLERANCE INDUCTION AND IMMUNODIAGNOSTICS
US9403889B2 (en) 2010-11-29 2016-08-02 Integrated Diagnostics, Inc. Diagnostic lung cancer panel and methods for its use
US8772043B2 (en) 2010-12-23 2014-07-08 Pioneer Hi Bred International Inc Universal peptide tags for transgene polypeptide analysis by mass spectrometry
CA2835806A1 (en) * 2011-05-13 2012-11-22 King's College London Methods and compositions relating to platelet sensitivity
EP2715367A2 (de) 2011-06-03 2014-04-09 University of South Alabama Verfahren und zusammensetzungen zum nachweis von endometrium- oder ovarialkrebs
US9506167B2 (en) 2011-07-29 2016-11-29 Ginkgo Bioworks, Inc. Methods and systems for cell state quantification
JP2014526682A (ja) 2011-09-12 2014-10-06 クリエイティクス エルエルシー 標的分子を検出する非侵襲的方法
CN103134874B (zh) * 2011-12-01 2015-05-20 成都康弘生物科技有限公司 一种测定蛋白中糖基的方法
JP6082026B2 (ja) 2011-12-21 2017-02-15 インテグレイティド ダイアグノスティクス,インコーポレイティド 肺癌診断用の組成物、方法及びキット
US9304137B2 (en) 2011-12-21 2016-04-05 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
US11913957B2 (en) 2011-12-21 2024-02-27 Biodesix, Inc. Compositions, methods and kits for diagnosis of lung cancer
AU2013208293B2 (en) 2012-01-09 2017-08-10 Serpin Pharma, Llc Peptides and methods of using same
US9452218B2 (en) 2012-03-09 2016-09-27 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
WO2013167153A1 (en) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
JP6296615B2 (ja) * 2012-11-06 2018-03-20 国立大学法人 宮崎大学 新規ペプチドおよびその用途
WO2014100717A2 (en) 2012-12-21 2014-06-26 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
WO2014160499A2 (en) 2013-03-13 2014-10-02 Creatics Llc Methods and compositions for detecting pancreatic cancer
GB201310150D0 (en) * 2013-06-07 2013-07-24 Electrophoretics Ltd Methods and compositions relating to alzheimer's disease
US9297805B2 (en) 2013-07-26 2016-03-29 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
US9594085B2 (en) 2014-02-03 2017-03-14 Integrated Diagnostics, Inc. Integrated quantification method for protein measurements in clinical proteomics
US10000533B2 (en) 2014-06-20 2018-06-19 Immatics Biotechnologies Gmbh Immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemia (CLL)
GB201411037D0 (en) * 2014-06-20 2014-08-06 Immatics Biotechnologies Gmbh Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL)
WO2016038608A1 (en) * 2014-09-08 2016-03-17 Carmel Haifa University Economic Corporation Ltd. Peptides derived from angiotensin receptor and use thereof
US10035823B2 (en) 2014-09-29 2018-07-31 The Regents Of The University Of California Compositions for expanding regulatory T cells (TREG), and treating autoimmune and inflammatory diseases and conditions
GB201505305D0 (en) * 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
CN109265517B (zh) 2015-03-27 2024-05-10 伊玛提克斯生物技术有限公司 用于各种肿瘤免疫治疗的肽和肽组合物
CA2996975C (en) 2015-08-28 2022-02-15 Serpin Pharma, Llc Methods for treatment of diseases
GB201520568D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd Peptides
GB201520550D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201520559D0 (en) * 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
CN110114680A (zh) 2016-05-05 2019-08-09 佰欧迪塞克斯公司 用于诊断肺癌的组合物、方法和试剂盒
US9960027B2 (en) 2016-05-25 2018-05-01 Thermo Finnigan Llc Analyzing a complex sample by MS/MS using isotopically-labeled standards
MY202410A (en) * 2017-09-01 2024-04-27 Venn Biosciences Corp Identification and use of glycopeptides as biomarkers for diagnosis and treatment monitoring
ES2710321A1 (es) * 2017-10-20 2019-04-24 Consejo Superior Investigacion Adn polimerasas independientes de cebador y su uso para la sintesis de adn
WO2020223646A1 (en) 2019-05-02 2020-11-05 Creatics Llc Methods for cancer detection by evaluation of alpha-1-antitrypsin (aat) and chymotrypsin-like elastase in gastrointestinal lavage fluid samples
CN110563844A (zh) * 2019-09-04 2019-12-13 华中农业大学 一种抗犬白介素31受体的多克隆抗体及其应用
WO2021050510A1 (en) * 2019-09-09 2021-03-18 The Wistar Institute Of Anatomy And Biology Engineered peptide and peptide mimetic compositions and methods
EP4329793A2 (de) * 2021-04-29 2024-03-06 Seer, Inc. Peptiddekorierte nanopartikel zur anreicherung spezifischer proteinuntermengen
CN113480629B (zh) * 2021-06-16 2022-08-19 复旦大学 区分肝癌和正常人的末端唾液酸化异构糖肽标志物及其筛查方法
US11542340B1 (en) 2021-10-29 2023-01-03 Biodesix, Inc. Antibodies targeting pulmonary nodule specific biomarkers and uses thereof
NL2030990B1 (en) * 2022-02-17 2023-09-01 Academisch Ziekenhuis Leiden T cell receptors directed against jchain and uses thereof
WO2024086826A2 (en) * 2022-10-21 2024-04-25 Quantum-Si Incorporated Polypeptidyl linkers
CN117969642A (zh) * 2024-04-02 2024-05-03 浙江大学 一种植物n-糖链的精准相对定量分析方法及应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2226032B (en) * 1988-12-16 1993-08-18 Urs Heimgartner Detection of glycoproteins
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5079336A (en) * 1989-06-23 1992-01-07 The Trustees Of The University Of Pennsylvania α-1-antichymotrypsin, analogues and methods of production
US5264563A (en) 1990-08-24 1993-11-23 Ixsys Inc. Process for synthesizing oligonucleotides with random codons
GB9112504D0 (en) * 1991-06-11 1991-07-31 Merck Sharp & Dohme Cell line
US5986076A (en) 1994-05-11 1999-11-16 Trustees Of Boston University Photocleavable agents and conjugates for the detection and isolation of biomolecules
DE69531545T2 (de) 1994-06-23 2004-06-24 Affymax Technologies N.V., Willemstad Photolabile verbindungen und verfahren für deren verwendung
DE69724428T3 (de) * 1996-06-07 2009-07-23 Poniard Pharmaceuticals, Inc., Seattle Humanisierte antikörper die an das gleiche antigen wie antikörper nr-lu-13 binden und deren verwendung in "pretargeting" verfahren
CA2272407C (en) * 1996-12-10 2012-07-31 Sloan-Kettering Institute For Cancer Research Method and compositions for stimulation of an immune response to a differentiation antigen stimulated by an altered differentiation antigen
US6046013A (en) * 1997-08-01 2000-04-04 Gti Process for identifying specific antibodies associated with HLA
ATE253126T1 (de) 1998-08-25 2003-11-15 Univ Washington Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
US6407210B1 (en) * 1998-11-09 2002-06-18 University Of Utah Research Foundation Nematode neuromuscular junction GABA receptors and methods related thereto
JP2003518364A (ja) * 1999-05-28 2003-06-10 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ 乳癌、胃癌および前立腺癌関連抗原ならびにそれらの使用
JP4048115B2 (ja) 2000-12-26 2008-02-13 ザ インスティチュート フォー システムズ バイオロジー 迅速かつ定量的なプロテオーム解析および関連した方法
EP1435957B1 (de) * 2001-04-30 2009-06-17 Vertex Pharmaceuticals Incorporated Inhibitoren von gsk-3 und kristallstrukturen von gsk-3beta-protein und -proteinkomplexen
AU2002341862C1 (en) * 2001-09-27 2009-01-29 Purdue Research Foundation Controlling isotope effects during fractionation of analytes
WO2003102018A2 (en) * 2002-06-03 2003-12-11 The Institute For Systems Biology Methods for quantitative proteome analysis of glycoproteins
WO2005007677A2 (en) * 2003-07-10 2005-01-27 The Institute For Systems Biology Affinity capture of peptides by microarray and related methods
US7593336B2 (en) * 2003-10-31 2009-09-22 Brocade Communications Systems, Inc. Logical ports in trunking
US7348416B2 (en) * 2003-11-21 2008-03-25 Applera Corporation Selective capture and enrichment of proteins expressed on the cell surface

Also Published As

Publication number Publication date
WO2005114221A2 (en) 2005-12-01
EP2093569A3 (de) 2009-11-11
DK1766412T3 (da) 2009-05-25
ATE427499T1 (de) 2009-04-15
EP2302393A1 (de) 2011-03-30
EP2302394A1 (de) 2011-03-30
EP1766412B1 (de) 2009-04-01
EP1766412A2 (de) 2007-03-28
WO2005114221A8 (en) 2006-05-04
US20100279382A1 (en) 2010-11-04
EP2302393A8 (de) 2011-08-03
EP2093569A2 (de) 2009-08-26
WO2005114221A3 (en) 2006-12-21
US20060141528A1 (en) 2006-06-29

Similar Documents

Publication Publication Date Title
DE602005013670D1 (de) Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen
DE60335733D1 (de) Verfahren zur solubilisierung von protein
DE60326012D1 (de) Verfahren zur Konzentration von Proteinen
DE60223561D1 (de) Verfahren zum nachweis von oxidativem stress sowie kit zur durchführung davon
ATE362530T1 (de) Verfahren und vorrichtung zur reinigung von nukleinsäuren
ATE520466T1 (de) Apparat und verfahren zur modifizierung von magnetisch inmmobilizierte biomolekulen
HUP0200400A2 (hu) Fehérjék izolálása és elemzése
DE50213504D1 (de) Verfahren und vorrichtung zur prädiktion von beweg
DE60214946D1 (de) Verfahren und System zur Bereitstellung von Informationen
DE69918089D1 (de) Btk inhibitoren und verfahren zur identifizierung und verwendung
DE60222864D1 (de) Verfahren und vorrichtung zur untersuchung von fluiden
DE60230927D1 (de) Fangverbindungen, ihre entnahme und verfahren zur analysierung des proteoms und von komplexen zusammensetzungen
WO2005012574A3 (en) Biological bar-code
ATA12472001A (de) Verfahren und chip zur analyse von nukleinsäuren
DE60027551D1 (de) Zusammensetzungen und verfahren zur regulierung des serumcholesterins
DE50213709D1 (de) Verfahren zur bereitstellung von zielführungshinweisen
DE60217589D1 (de) Vorrichtung und Verfahren zur Detektion von weissen Linien
DE50203510D1 (de) Verfahren zur erkennung und identifizierung von objekten
DE50207337D1 (de) Anordnung und verfahren zur ermittlung von kenngrössen
DE602004030041D1 (de) Verfahren und zusammensetzungen zur identifikation von rna-bindenden proteinen
DE60028114D1 (de) Verfahren zur Analyse von ausgeatmetem Gas
ATE506370T1 (de) Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen
DE50204097D1 (de) Verfahren zur ermittlung von auswirkungen von konstruktionsentscheidungen
DE60140251D1 (de) Verfahren zur analyse von komponenten biologischer proben
DE10393421D2 (de) Verfahren zur Anreicherung und zum Nachweis von pathologisch veränderten Prion-Proteinen (PRPSC)

Legal Events

Date Code Title Description
8364 No opposition during term of opposition