DE60223561D1 - Verfahren zum nachweis von oxidativem stress sowie kit zur durchführung davon - Google Patents

Verfahren zum nachweis von oxidativem stress sowie kit zur durchführung davon

Info

Publication number
DE60223561D1
DE60223561D1 DE60223561T DE60223561T DE60223561D1 DE 60223561 D1 DE60223561 D1 DE 60223561D1 DE 60223561 T DE60223561 T DE 60223561T DE 60223561 T DE60223561 T DE 60223561T DE 60223561 D1 DE60223561 D1 DE 60223561D1
Authority
DE
Germany
Prior art keywords
oxidative stress
kit
implementing
risk factor
individual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60223561T
Other languages
English (en)
Other versions
DE60223561T2 (de
Inventor
Joel Pincemail
Jacques Piette
Daniel Marechal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Probiox SA
Original Assignee
Probiox SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Probiox SA filed Critical Probiox SA
Application granted granted Critical
Publication of DE60223561D1 publication Critical patent/DE60223561D1/de
Publication of DE60223561T2 publication Critical patent/DE60223561T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
DE60223561T 2001-08-14 2002-08-13 Verfahren zum nachweis von oxidativem stress sowie kit zur durchführung davon Expired - Lifetime DE60223561T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BE200100545 2001-08-14
BE2001/0545A BE1014949A3 (fr) 2001-08-14 2001-08-14 Procede de detection de stress oxydant et trousse pour sa mise en oeuvre.
PCT/EP2002/009079 WO2003016527A2 (en) 2001-08-14 2002-08-13 Process for the detection of oxidative stress and kit for its implementation

Publications (2)

Publication Number Publication Date
DE60223561D1 true DE60223561D1 (de) 2007-12-27
DE60223561T2 DE60223561T2 (de) 2008-05-29

Family

ID=3897081

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60223561T Expired - Lifetime DE60223561T2 (de) 2001-08-14 2002-08-13 Verfahren zum nachweis von oxidativem stress sowie kit zur durchführung davon

Country Status (7)

Country Link
US (1) US7288374B2 (de)
EP (1) EP1423518B1 (de)
AT (1) ATE378404T1 (de)
BE (1) BE1014949A3 (de)
DE (1) DE60223561T2 (de)
ES (1) ES2296987T3 (de)
WO (1) WO2003016527A2 (de)

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Publication number Priority date Publication date Assignee Title
GB0225885D0 (en) * 2002-11-06 2002-12-11 Isis Innovation Quantifying exposure to stress
EP1565753A2 (de) * 2002-11-21 2005-08-24 The University Of Leicester Hypoxie-markern aus körperlichen flüssigkeiten
US20050065184A1 (en) * 2003-08-29 2005-03-24 Aaipharma Inc. Method of reducing the risk of oxidative stress
GB0409153D0 (en) * 2004-04-23 2004-05-26 Randox Lab Ltd Method of diagnosis
ES2315034B1 (es) * 2004-07-02 2009-12-30 Laboratorios Indas, S.A. Proteina de choque termico 27 (hsp-27) como marcador de enfermedad cardiovascular.
WO2006118988A2 (en) * 2005-04-29 2006-11-09 University Of Tennessee Research Foundation Cellular biomarker antioxidant assay and uses thereof
FR2894030B1 (fr) * 2005-11-30 2008-07-04 Michel Brack Procede de determination d'un score representatif du stress oxydatif d'un patient, sur une echelle de 0 a 10
EP2024517A2 (de) * 2006-05-31 2009-02-18 Health Research, Inc. Verfahren zur vorhersage der empfänglichkeit für eine strahlungspneumonitis
US7550299B2 (en) * 2006-08-03 2009-06-23 The United States Of America As Represented By The Department Of Veterans Affairs Method for predicting onset/risk of atrial fibrillation (AF)
FR2923609A1 (fr) 2007-11-13 2009-05-15 Thierry Patrice Test pour la mesure de la resistance au stress oxydant et ses applications
WO2009067550A1 (en) * 2007-11-19 2009-05-28 Bionovo, Inc. Methods of detecting and treatment of cancers using scuttelaria barbata extract
WO2012094580A2 (en) 2011-01-07 2012-07-12 High Point Pharmaceuticals, Llc Compounds that modulate oxidative stress
US8937213B2 (en) 2011-05-21 2015-01-20 Christopher E. Hopkins Transgenic biosensors
WO2013035071A1 (en) 2011-09-08 2013-03-14 Yeda Research And Development Co. Ltd. Novel risk biomarkers for lung cancer
RU2534821C2 (ru) * 2012-05-18 2014-12-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" Способ диагностики окислительного стресса измерением экспрессии кислородчувствительных генов (варианты)
EP2931854A1 (de) 2012-12-14 2015-10-21 The Procter & Gamble Company Duftstoffe
US20150328337A1 (en) * 2012-12-19 2015-11-19 The Johns Hopkins University Protection from oxidative damage by gene transfer by glutamate cysteine ligase and glutathione synthase
MX2015012303A (es) * 2013-03-15 2015-12-16 Procter & Gamble Un metodo no invasivo para medir el estres oxidativoy daño oxidativo de los biomarcadores cutaneos.
RU2545900C2 (ru) * 2013-05-07 2015-04-10 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт кардиологии" Сибирского отделения Российской академии медицинских наук Способ диагностики апоптоза лимфоцитов
RU2540500C2 (ru) * 2013-05-07 2015-02-10 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт кардиологии" Сибирского отделения Российской академии медицинских наук Способ прогнозирования ранней стадии апоптоза
US9995758B1 (en) * 2014-10-31 2018-06-12 Western Autotroph Company LLC Methods and systems for controlling oxidative stress in humans and animals
WO2016077467A1 (en) * 2014-11-11 2016-05-19 The Johns Hopkins University Biomarkers useful in the treatment of subjects having diseases of the eye
WO2017210360A1 (en) 2016-05-31 2017-12-07 Cardiovax, Llc Methods for diagnosing and treating systemic lupus erythematosus
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
US11091433B2 (en) 2017-09-20 2021-08-17 Nacuity Pharmaceutials, Inc. Method for preparation of N-acetyl cysteine amide and derivatives thereof
US11548851B2 (en) 2017-09-20 2023-01-10 Nacuity Pharmaceuticals, Inc. Method for preparation of n-acetyl cysteine amide and derivatives thereof
EP3684756A4 (de) 2017-09-20 2020-10-28 NaCuity Pharmaceuticals, Inc. Verfahren zur herstellung von n-acetylcysteinamid und derivaten davon
US20190135741A1 (en) 2017-11-09 2019-05-09 Nacuity Pharmaceuticals, Inc. Methods of Making Deuterium-Enriched N-acetylcysteine Amide (D-NACA) and (2R, 2R')-3,3'-Disulfanediyl BIS(2-Acetamidopropanamide) (DINACA) and Using D-NACA and DINACA to Treat Diseases Involving Oxidative Stress
CN109797133A (zh) * 2019-01-09 2019-05-24 珠海金肽生物科技有限公司 多潜能细胞培养组合物及制备方法和应用
AU2020206139A1 (en) 2019-01-11 2021-07-29 Nacuity Pharmaceuticals, Inc. Treatment of age-related macular degeneration, glaucoma, and diabetic retinopathy with N-acetylicysteine amide (NACA) or 2R,2R')-3-3'-disulfanediyl bis (2-acetamidopropanamide) (diNACA)
CN112684020B (zh) * 2020-12-01 2023-12-29 哈尔滨医科大学 一种用于评价个体锌营养状态的生物标志物及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2056790T3 (es) * 1986-01-17 1994-10-16 Preventive Medicine Inst Ensayo para determinar la predisposicion o susceptibilidad a enfermedades asociadas con dna.
IL129872A0 (en) * 1996-11-12 2000-02-29 Qbi Entpr Ltd Method for identifying translationally regulated genes
JP2002504812A (ja) * 1997-05-21 2002-02-12 クローンテック ラボラトリーズ，インコーポレイテッド 核酸アレイ
WO1999058718A1 (en) * 1998-05-11 1999-11-18 Quark Biotech Inc. Method for identifying genes
JP2002535956A (ja) * 1998-05-15 2002-10-29 クォーク バイオテック インコーポレイテッド 物理的ストレスにより誘発される遺伝子、その発現産物およびその使用方法
EP1032833A2 (de) * 1998-05-29 2000-09-06 Nikken Foods Co., Ltd. Verwendung eines diagnostischen diagramms von oxidativem stress als gesundheitsindikator
EP1105532A1 (de) * 1998-08-14 2001-06-13 The Trustees Of The University Of Pennsylvania Zusammensetzungen, kits, sowie verfahren zur hydrodynamischen stress-gekoppelten regulation der genexpression
WO2000065095A2 (en) * 1999-04-23 2000-11-02 Clontech Laboratories, Inc. Methods and compositions for performing array based hybridization assays
US6607885B1 (en) * 1999-10-15 2003-08-19 E. I. Du Pont De Nemours And Company Method for high-density microarray medicated gene expression profiling
AU1443001A (en) 1999-10-29 2001-05-14 Cleveland Clinic Foundation, The Method and apparatus for predicting male infertility
WO2001046468A2 (en) * 1999-12-21 2001-06-28 Eirx Therapeutics Ltd Screening method for ros-induced apoptosis in a cell
US6541265B2 (en) * 2001-05-09 2003-04-01 University Of Florida Method and system to test a substance for inflammatory or oxidant properties
AU2003207552A1 (en) * 2002-01-29 2003-09-02 James D. Talton Methods of collecting and analyzing human breath

Also Published As

Publication number Publication date
BE1014949A3 (fr) 2004-07-06
WO2003016527A2 (en) 2003-02-27
US7288374B2 (en) 2007-10-30
EP1423518B1 (de) 2007-11-14
DE60223561T2 (de) 2008-05-29
WO2003016527A3 (en) 2003-12-31
EP1423518A2 (de) 2004-06-02
ES2296987T3 (es) 2008-05-01
ATE378404T1 (de) 2007-11-15
US20050112572A1 (en) 2005-05-26

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