AU2014232782B2 - Device and associated methods for performing luminescence and fluorescence measurements of a sample - Google Patents

Device and associated methods for performing luminescence and fluorescence measurements of a sample Download PDF

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Publication number
AU2014232782B2
AU2014232782B2 AU2014232782A AU2014232782A AU2014232782B2 AU 2014232782 B2 AU2014232782 B2 AU 2014232782B2 AU 2014232782 A AU2014232782 A AU 2014232782A AU 2014232782 A AU2014232782 A AU 2014232782A AU 2014232782 B2 AU2014232782 B2 AU 2014232782B2
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Australia
Prior art keywords
fiber optic
sample
optical
optics
light
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AU2014232782A
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AU2014232782A8 (en
AU2014232782A1 (en
Inventor
Ronald Norman Diamond
Steve Michael GANN
Marinela GOMBOSEV
Eric Darnell HALL
Tae Ho Hwang
John Lewis Morton
Anatoly Moskalev
Dennis RIEGER
Bruce Alan Sargeant
Mark David Van Cleve
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Hycor Biomedical LLC
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Hycor Biomedical LLC
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Application granted granted Critical
Publication of AU2014232782B2 publication Critical patent/AU2014232782B2/en
Priority to AU2018220044A priority Critical patent/AU2018220044A1/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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    • G01N21/645Specially adapted constructive features of fluorimeters
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    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
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    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
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    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • G01N2201/12Circuits of general importance; Signal processing
    • G01N2201/127Calibration; base line adjustment; drift compensation
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
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  • Rehabilitation Therapy (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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AU2014232782A 2013-03-15 2014-03-17 Device and associated methods for performing luminescence and fluorescence measurements of a sample Ceased AU2014232782B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2018220044A AU2018220044A1 (en) 2013-03-15 2018-08-22 Device and associated methods for performing luminescence and fluorescence measurements of a sample

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361791295P 2013-03-15 2013-03-15
US201361791879P 2013-03-15 2013-03-15
US61/791,295 2013-03-15
US61/791,879 2013-03-15
PCT/US2014/030414 WO2014145619A1 (en) 2013-03-15 2014-03-17 Device and associated methods for performing luminescence and fluorescence measurements of a sample

Related Child Applications (1)

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AU2018220044A Division AU2018220044A1 (en) 2013-03-15 2018-08-22 Device and associated methods for performing luminescence and fluorescence measurements of a sample

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AU2014232782A1 AU2014232782A1 (en) 2015-09-24
AU2014232782A8 AU2014232782A8 (en) 2016-06-16
AU2014232782B2 true AU2014232782B2 (en) 2018-05-24

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AU2014232782A Ceased AU2014232782B2 (en) 2013-03-15 2014-03-17 Device and associated methods for performing luminescence and fluorescence measurements of a sample
AU2014232882A Ceased AU2014232882B2 (en) 2013-03-15 2014-03-17 Automated immunoanalyzer system for performing diagnostic assays for allergies and autoimmune diseases
AU2018220044A Abandoned AU2018220044A1 (en) 2013-03-15 2018-08-22 Device and associated methods for performing luminescence and fluorescence measurements of a sample

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AU2018220044A Abandoned AU2018220044A1 (en) 2013-03-15 2018-08-22 Device and associated methods for performing luminescence and fluorescence measurements of a sample

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US (13) US9075055B2 (https=)
EP (3) EP3933384A1 (https=)
JP (3) JP6389868B2 (https=)
CN (4) CN107817232B (https=)
AU (3) AU2014232782B2 (https=)
CA (2) CA2905165A1 (https=)
HK (2) HK1220759A1 (https=)
WO (2) WO2014145581A1 (https=)

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US8866912B2 (en) 2013-03-10 2014-10-21 Pelican Imaging Corporation System and methods for calibration of an array camera using a single captured image
EP3933384A1 (en) 2013-03-15 2022-01-05 Hycor Biomedical, LLC Device and associated method for performing luminescence and fluorescence measurements of a sample
KR20170005401A (ko) * 2014-05-19 2017-01-13 시스템 인스트루먼츠 컴퍼니 리미티드 분석 장치
US10661268B2 (en) * 2014-06-30 2020-05-26 Beacon Technologies, LLC Pipette tip system, device and method of use
EP3262397B1 (en) * 2015-02-27 2022-06-08 Hycor Biomedical, LLC Apparatuses for suspending and washing the contents of a plurality of cuvettes
AU2015389978A1 (en) * 2015-03-30 2017-09-28 Hycor Biomedical, Inc. Automated immunoanalyzer system for performing diagnostic assays for autoimmune and infectious diseases
ES3038129T3 (en) 2015-06-26 2025-10-09 Abbott Lab Rotating device in a diagnostic analyzer
WO2017011560A1 (en) 2015-07-15 2017-01-19 Hycor Biomedical, Llc. Customizable instrument
EP3325965B1 (en) * 2015-07-23 2022-02-09 Hycor Biomedical, Inc. On-board kitting
CN105403692A (zh) * 2015-11-17 2016-03-16 苏州浩欧博生物医药有限公司 检测屋尘螨过敏原特异性IgE抗体的试剂盒及方法
CN105353134A (zh) * 2015-11-17 2016-02-24 苏州浩欧博生物医药有限公司 检测狗毛过敏原特异性IgE抗体的试剂盒及方法
CN105353133A (zh) * 2015-11-17 2016-02-24 苏州浩欧博生物医药有限公司 检测粉尘螨过敏原特异性IgE抗体的试剂盒及方法
TW201832726A (zh) * 2016-11-01 2018-09-16 美商海科生醫有限責任公司 可基於輸入數據建議檢測之免疫檢測系統
CN109470866A (zh) * 2016-11-22 2019-03-15 博阳生物科技(上海)有限公司 免疫测定方法、用于鉴定免疫测定的系统和试剂盒
CN107389615B (zh) * 2016-12-20 2020-03-24 苏州赛德福科学仪器有限公司 一种蒸发光检测装置及基于该装置的蒸发光测量方法
CN107703123A (zh) * 2017-09-15 2018-02-16 江苏浩欧博生物医药股份有限公司 一种血清类胰蛋白酶的化学发光定量检测试剂盒及其制备方法和检测方法
EP3685131B1 (en) 2017-09-19 2022-09-07 Beckman Coulter, Inc. Analog light measuring and photon counting in chemiluminescence measurements
CN107766772B (zh) * 2017-11-23 2024-05-17 安派科生物医学科技(丽水)有限公司 一种样品录入装置
CN108593949B (zh) * 2018-02-11 2024-01-26 金博特(北京)生物科技有限公司 一种化学发光免疫分析仪
WO2020044151A1 (en) 2018-08-29 2020-03-05 CANNAVALE, Giuseppe System and method for solid phase analysis of biological samples
IT201800008227A1 (it) * 2018-08-29 2020-02-29 Cannavale Giuseppe Metodo e sistema per la determinazione di immunoglobuline totali o dirette contro allergeni o altre molecole in campioni acquosi
US12163885B2 (en) 2018-08-31 2024-12-10 Shimadzu Corporation Analysis device, analysis method, trace liquid collection device, and trace liquid collection method
CN109030809B (zh) * 2018-10-31 2021-08-20 蓝怡科技集团股份有限公司 一种过敏原IgE抗体自动分析仪
WO2020157789A1 (ja) * 2019-01-28 2020-08-06 株式会社島津製作所 分析装置
CN110596371B (zh) * 2019-09-20 2023-04-07 郑州安图生物工程股份有限公司 一种全自动化学发光测定仪磁珠回收率和试剂针精密性评估方法以及试剂盒
CN111518780B (zh) * 2020-06-04 2022-06-14 郑州伊美诺生物技术有限公司 脱辅基辣根过氧化物酶的制备方法
US11480565B2 (en) 2020-06-12 2022-10-25 Bio-Rad Laboratories, Inc. Automated immunoassay
GB202009823D0 (en) * 2020-06-26 2020-08-12 Stimson William Howard Automated quantitative assay device and a method of performing the quantitative assays
CN112748248B (zh) * 2020-12-23 2022-06-14 郑州安图生物工程股份有限公司 一种牛奶过敏原特异性IgE检测试剂盒
CN112666154A (zh) * 2021-01-26 2021-04-16 安图实验仪器(郑州)有限公司 光学信号检测装置
JP7693173B2 (ja) * 2021-09-24 2025-06-17 学校法人杏林学園 マカダミアナッツアレルゲン特異的IgEを検出するための方法、マカダミアナッツアレルギー診断用体外診断薬、マカダミアナッツアレルゲン特異的IgE検出用キット、およびマカダミアナッツアレルゲンの検出方法
IT202200010064A1 (it) * 2022-05-16 2023-11-16 Optoelettronica Italia S R L Dispositivo e metodo per il rilevamento di biomolecole
WO2025155731A1 (en) * 2024-01-16 2025-07-24 Beckman Coulter, Inc. Alternative substrate pack for automated clinical analyzer and methods of use
WO2025155701A1 (en) * 2024-01-16 2025-07-24 Beckman Coulter, Inc. Automated clinical analyzer with alternative substrate and method of use
CN118501432B (zh) * 2024-07-18 2024-09-27 山东省动物疫病预防与控制中心(山东省人畜共患病流调监测中心) 布鲁氏菌病cf-elisa抗体检测试剂盒

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1054250A1 (en) * 1999-01-25 2000-11-22 Laboratory of Molecular Biophotonics Pipette adaptor, pipette for absorbance measurement, tip, and method and apparatus for absorbance measurement

Family Cites Families (161)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT287916B (de) * 1969-04-29 1971-02-10 Schwarz O Verfahren zur Herstellung eines in der Geburtshilfe wertvollen prophylaktischen Mittels
US3628682A (en) 1970-06-29 1971-12-21 Beckman Instruments Inc Lighttight sample introduction system
US4291230A (en) * 1979-03-07 1981-09-22 Baxter Travenol Laboratories, Inc. Fluorometric analyzer including shutter means for simultaneously shielding sample and photodetector during sample change
US5643566A (en) * 1982-09-23 1997-07-01 Cetus Corporation Formulation processes for lipophilic proteins
US4849337A (en) * 1983-01-31 1989-07-18 Minnesota Mining And Manufacturing Company Assaying allergen specific IgE levels with fluorogenic enzyme labeled antibody
FI831936A0 (fi) * 1983-05-30 1983-05-30 Labsystems Oy Anordning foer maetning av fluorescens, turbiditet, luminescens eller absorption
GB8505899D0 (en) 1985-03-07 1985-04-11 Boots Celltech Diagnostics Assay reagents
US4778751A (en) 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
US5320808A (en) * 1988-08-02 1994-06-14 Abbott Laboratories Reaction cartridge and carousel for biological sample analyzer
JP2656564B2 (ja) * 1988-08-26 1997-09-24 株式会社日立製作所 免疫分析方法
DE3901857A1 (de) 1989-01-23 1990-07-26 Boehringer Mannheim Gmbh Verfahren zur bestimmung von hiv 2 antikoerpern
US5196306A (en) 1989-03-29 1993-03-23 E. I. Du Pont De Nemours And Company Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system
JPH04106471A (ja) * 1990-08-28 1992-04-08 Hitachi Ltd 生体関連物質の測定装置
ATE193600T1 (de) 1990-11-20 2000-06-15 Dade Behring Marburg Gmbh Verfahren zur stabilisierung von enzym-konjugaten
SE9004047L (sv) 1990-12-19 1992-06-20 Francisco Batista Metod foer immobilisering av tiolfoereningar via aktivering av polymerer, aktiverade polymerer, och produkter erhaallna med metoden
JPH04348258A (ja) * 1991-05-27 1992-12-03 Kowa Co 多チャンネル光学測定装置
DK130991D0 (da) 1991-07-04 1991-07-04 Immunodex K S Polymere konjugater
US5395938A (en) 1992-08-21 1995-03-07 Nichols Institute Diagnostics Biotinylated chemiluminescent labels and their conjugates, assays and assay kits
JP3207933B2 (ja) 1992-09-09 2001-09-10 株式会社ヤトロン アクリジニウム誘導体の発光方法及びそれを用いた検査対象物質の検出方法
US5736410A (en) 1992-09-14 1998-04-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US6399397B1 (en) 1992-09-14 2002-06-04 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US5674698A (en) 1992-09-14 1997-10-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US5698397A (en) 1995-06-07 1997-12-16 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US6087188A (en) 1992-11-13 2000-07-11 Alk A/S Two-site immunoassay for an antibody with chemiluminescent label and biotin bound ligand
US5395752A (en) 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays
AU679008B2 (en) 1993-05-06 1997-06-19 Chiron Diagnostics Corporation Mixed luminescent conjugate test assays
US5468453A (en) 1993-06-14 1995-11-21 Cirrus Diagnostics, Inc. Low carryover pipette probe
US6348310B1 (en) 1994-03-04 2002-02-19 Promega Corporation Quantitation of individual protein kinase activity
GB2289334B (en) 1994-05-10 1998-08-26 Molecular Light Technology Lim Enzyme linked chemiluminescent assay
DE4418223A1 (de) 1994-05-25 1995-11-30 Boehringer Mannheim Gmbh Verfahren zum Nachweis des Vorliegens eines Insulin-abhängigen Diabetes mellitus
US6800452B1 (en) 1994-08-08 2004-10-05 Science Applications International Corporation Automated methods for simultaneously performing a plurality of signal-based assays
DE4439452A1 (de) 1994-11-04 1996-05-09 Boehringer Mannheim Gmbh Antikörperklassenspezifisches Entstörungsreagenz
JP2815545B2 (ja) * 1994-11-07 1998-10-27 日本分光株式会社 液体クロマトグラフ用検出器
WO1996024044A1 (en) 1995-02-02 1996-08-08 Chugai Seiyaku Kabushiki Kaisha Method of assaying specimen substance by controlling dose of chemiluminescence
EP0821726B1 (en) 1995-03-10 2014-05-07 Meso Scale Technologies, LLC. Multi-array, multi-specific electrochemiluminescence testing
US6140045A (en) 1995-03-10 2000-10-31 Meso Scale Technologies Multi-array, multi-specific electrochemiluminescence testing
JPH08313539A (ja) * 1995-05-16 1996-11-29 Nittec Co Ltd 容器およびこの容器を用いた液体撹拌・洗浄・磁性体微粒子捕集方法並びに該容器を用いた免疫化学検査装置
US5879885A (en) 1995-06-07 1999-03-09 Gen-Probe Incorporated Compositions for detecting and quantifying biological samples
US5690907A (en) 1995-06-08 1997-11-25 The Jewish Hospital Of St. Louis Avidin-biotin conjugated emulsions as a site specific binding system
IL114149A0 (en) 1995-06-14 1995-10-31 Yeda Res & Dev Modified avidin and streptavidin molecules and use thereof
US5770700A (en) * 1996-01-25 1998-06-23 Genetics Institute, Inc. Liquid factor IX formulations
US5776487A (en) 1996-04-19 1998-07-07 Pasteur Sanofi Diagnostics Liposome reagents for immunoassays
SE9602234D0 (sv) 1996-06-06 1996-06-06 Pharmacia Ab A novel diagnostic method utilizing ECP, and reagents to be used in the methods
US5942407A (en) 1996-06-25 1999-08-24 Immunomatrix, Inc. Light-emitting immunoassay
GB9712818D0 (en) 1996-07-08 1997-08-20 Cambridge Antibody Tech Labelling and selection of specific binding molecules
SE9603379D0 (sv) 1996-09-17 1996-09-17 Pharmacia & Upjohn Ab Anordning för att detektera när en mätsond kommer i kontakt med en vätskeyta
US5776785A (en) 1996-12-30 1998-07-07 Diagnostic Products Corporation Method and apparatus for immunoassay using fluorescent induced surface plasma emission
US6432662B1 (en) 1997-04-15 2002-08-13 Pierce Chemical Company Assay of peroxidase activity
US6165800A (en) 1997-05-30 2000-12-26 Bayer Corporation Chemiluminescent energy transfer conjugates and their uses as labels in binding assays
US5929049A (en) 1997-08-08 1999-07-27 Dade Behring Marburg Gmbh Polysaccharide conjugates of biomolecules
JP3366842B2 (ja) * 1997-08-29 2003-01-14 エーザイ株式会社 電気化学発光測定用セル
US5922558A (en) 1997-09-12 1999-07-13 Lumigen, Inc. Methods and compositions for generating chemiluminescence with a peroxidase
EP1029244A4 (en) 1997-10-02 2003-07-23 Aclara Biosciences Inc CAPILLAR ASSAY WITH SEPARATION OF FREE AND TIED SPECIES
US6180340B1 (en) 1997-10-31 2001-01-30 Gen-Probe Incorporated Extended dynamic range assays
SE9704935D0 (sv) 1997-12-30 1997-12-30 Pharmacia & Upjohn Diag Ab Analysmetod med partiklar
US6235480B1 (en) 1998-03-13 2001-05-22 Promega Corporation Detection of nucleic acid hybrids
US6068979A (en) 1998-04-22 2000-05-30 Lumigen, Inc. Simplified sequential chemiluminescent detection
SE9801563D0 (sv) 1998-04-30 1998-04-30 Pharmacia & Upjohn Diag Ab Förfarande med separation och kit att användas vid förfarandet
US6153442A (en) 1998-05-20 2000-11-28 Dade Behring Inc. Reagents and methods for specific binding assays
US6303325B1 (en) 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes
US6379909B1 (en) 1998-06-24 2002-04-30 Alk-Abello A/S Method of detecting an antibody in a liquid sample
DE69940433D1 (de) 1998-08-11 2009-04-02 Siemens Healthcare Diagnostics Im nahen infrarot chemilumineszente akridinium derivate und ihre verwendung
US6236456B1 (en) * 1998-08-18 2001-05-22 Molecular Devices Corporation Optical system for a scanning fluorometer
US6399299B1 (en) 1998-11-02 2002-06-04 Perkinelmer Life Sciences, Inc. Amplified array analysis system
US7759133B2 (en) 1998-12-22 2010-07-20 Alk-Abello A/S Method of detecting and/or quantifying a specific IgE antibody in a liquid sample
WO2001003721A1 (en) 1999-07-12 2001-01-18 Merlin Biomedical & Pharmaceutical, Ltd. Improved assays for detecting human immunodeficiency virus infection
US6783948B1 (en) 1999-07-30 2004-08-31 Bayer Corporation Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes
US6902889B1 (en) 1999-08-06 2005-06-07 Pharmacia Diagnostics Ab Analytical method and advice
AU770488B2 (en) 1999-08-06 2004-02-26 Maiia Ab Analytical method and apparatus
US8153367B2 (en) 1999-10-29 2012-04-10 Perkinelmer Las, Inc. Amplified array analysis system
US6852986B1 (en) 1999-11-12 2005-02-08 E. I. Du Pont De Nemours And Company Fluorometer with low heat-generating light source
US6812038B1 (en) 1999-11-18 2004-11-02 Pharmacia Diagnostics Ab Assay device and use thereof
US7018810B1 (en) 1999-12-07 2006-03-28 Amgen Inc. Chordin-like molecules and uses thereof
US7018847B2 (en) 2000-05-05 2006-03-28 Pharmacia Diagnostics Ab Assay device with timer function
US6958214B2 (en) 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
US6777198B2 (en) 2000-10-11 2004-08-17 Pharmacia Diagnostics Ab Assay method and kit therefor
WO2002037078A2 (en) * 2000-10-31 2002-05-10 Dpc Cirrus, Inc. Automated immunoassay analyzer and method of using the same
US20030031685A1 (en) 2000-12-29 2003-02-13 Sabine Stumvoll Pure allergen component
US7247726B2 (en) 2001-02-26 2007-07-24 Lumigen, Inc. Compounds for generating chemiluminescence with a peroxidase
US6872828B2 (en) 2001-12-20 2005-03-29 Lumigen, Inc. Compounds for generating chemiluminescence with a peroxidase
US7143960B2 (en) * 2001-03-14 2006-12-05 3M Innovative Properties Company Liquid sample reservoir suitable for use with a spraying apparatus
JP2002272498A (ja) * 2001-03-21 2002-09-24 Olympus Optical Co Ltd 生化学的検査方法
KR20020075996A (ko) 2001-03-27 2002-10-09 (주) 바이오알레텍 잎응애(귤응애, 점박이응애, 사과응애) 조항원을 함유하는피부시험 시약 및 혈청 특이 IgE, IgG 아형 항체검출 키트
US6670113B2 (en) 2001-03-30 2003-12-30 Nanoprobes Enzymatic deposition and alteration of metals
US7888060B2 (en) 2001-03-30 2011-02-15 Nanoprobes, Inc. Method for detecting a target using enzyme directed deposition of elemental metal
US7691598B2 (en) 2001-03-30 2010-04-06 Nanoprobes, Inc. Method for detecting a target molecule by metal deposition
US7364872B1 (en) 2001-03-30 2008-04-29 Nanoprobes Test methods using enzymatic deposition and alteration of metals
US7262019B2 (en) 2001-05-03 2007-08-28 Immunetics, Inc. System and methods for detection of Bacillus anthracis related analytes in biological fluids
WO2002090930A2 (en) 2001-05-09 2002-11-14 Biofx Laboratories, Inc. Stabilizing peroxides with stannous halides
WO2002097122A1 (en) 2001-05-26 2002-12-05 One Cell Systems, Inc. Secretion of proteins by encapsulated cells
DE10136863A1 (de) * 2001-07-28 2003-02-20 Berthold Tech Gmbh & Co Kg Vorrichtung zur wahlweisen Messung von insbesondere Lumineszenz- und/oder Fluoreszenzstrahlung
SE0103072D0 (sv) 2001-09-17 2001-09-17 Pharmacia Diagnostics Ab Multi-analyte assay device with multi-spot detection zone
CN100593721C (zh) 2001-11-27 2010-03-10 迪尔基因国际有限公司 用于病人的样本中生物化学标记物的早期和同步检测的免疫测定法和试剂盒
US6972326B2 (en) 2001-12-03 2005-12-06 Molecular Probes, Inc. Labeling of immobilized proteins using dipyrrometheneboron difluoride dyes
US20030109067A1 (en) 2001-12-06 2003-06-12 Immunetech, Inc. Homogeneous immunoassays for multiple allergens
US7560556B2 (en) 2001-12-20 2009-07-14 Lumigen, Inc. Assay methods using chemiluminescent detection of peroxidase
CA2483868A1 (en) 2002-05-03 2004-05-21 Molecular Probes, Inc. Compositions and methods for detection and isolation of phosphorylated molecules
US7445894B2 (en) 2002-05-03 2008-11-04 Molecular Probes, Inc. Compositions and methods for detection and isolation of phosphorylated molecules
AU2003245317A1 (en) * 2002-05-20 2003-12-12 The Government Of The United States Of America As Represented By The Secretary, Department Of Health Elisa assay of serum soluble cd22 to assess tumor burden/relapse in subjects with leukemia and lymphoma
US6897036B2 (en) 2002-06-06 2005-05-24 Lumigen, Inc. Fluorescent detection of peroxidase enzymes
US8314210B2 (en) 2002-07-12 2012-11-20 Dana-Farber Cancer Institute, Inc. Compositions and methods for the generation of MHC class II compounds by peptide exchange
CA2494310A1 (en) 2002-08-01 2004-02-12 Immunomedics, Inc. Alpha-fetoprotein immu31 antibodies and fusion proteins and methods of use thereof
CN100442052C (zh) * 2002-08-15 2008-12-10 陕西西大北美基因股份有限公司 磁性荧光微球及其制备方法和采用该磁性荧光微球进行生物分子检测的方法
US6924154B2 (en) 2002-08-20 2005-08-02 Quest Diagnostics Investments Incorporated Hydrophilic chemilumescent acridinium labeling reagents
US7285424B2 (en) * 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7319041B2 (en) 2002-09-27 2008-01-15 Siemens Medical Solutions Diagnostic Applications of acridinium compounds and derivatives in homogeneous assays
US7309615B2 (en) 2002-09-27 2007-12-18 Siemens Medical Solutions Diagnostic High quantum yield acridinium compounds and their uses in improving assay sensitivity
SE0300958D0 (sv) 2003-04-02 2003-04-02 Pharmacia Diagnostics Ab Analytical method and kit therof
US7393638B2 (en) 2003-07-01 2008-07-01 Asiagen Corporation Assay system and methods for detecting SARS-CV
US7521184B2 (en) 2003-08-22 2009-04-21 Sirna Therapeutics, Inc. Detection and quantitation of nucleic acid molecules in biological samples
JP2005147826A (ja) * 2003-11-14 2005-06-09 Hamamatsu Photonics Kk 蛍光測定装置
SE528508C2 (sv) 2004-03-30 2006-11-28 Phadia Ab Provtagningsanordning för uttag och insamling av ett prov av kapillärt blod
WO2005114218A2 (en) 2004-05-15 2005-12-01 Genentech, Inc. Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
US20060008895A1 (en) 2004-07-08 2006-01-12 Hsiu-Mei Chen Microarray chip for detection of immunoglobulin
DE102005026163A1 (de) 2004-08-24 2006-03-02 Dade Behring Marburg Gmbh Gegen den Marburg I Polymorphismus der Faktor VII aktivierenden Protease (FSAP) gerichtete Antikörper, ihre Herstellung und Verwendung
CN103091485A (zh) 2004-11-03 2013-05-08 艾瑞斯国际有限公司 用于亲和分离的微泡
US7074622B2 (en) 2004-11-15 2006-07-11 Eastman Kodak Company Method and system for sorting and separating particles
US7183119B2 (en) 2004-11-15 2007-02-27 Eastman Kodak Company Method for sensitive detection of multiple biological analytes
US7479391B2 (en) * 2004-12-10 2009-01-20 Tecan Trading Ag Pipetting apparatus with integrated liquid level and/or gas bubble detection
JP2006170662A (ja) * 2004-12-13 2006-06-29 Olympus Corp 粒子状担体およびこれを用いた生体関連物質の処理方法
US20080124738A1 (en) 2005-03-01 2008-05-29 Pritest, Inc Compositions and methods of testing for tuberculosis and mycobacterium infection
WO2006116683A1 (en) 2005-04-27 2006-11-02 The Trustees Of The University Of Pennsylvania Nanostructure enhanced luminescence
US20060252097A1 (en) 2005-05-02 2006-11-09 The Curators Of The University Of Missouri Detection of carbohydrate biomarkers
GB2425974A (en) 2005-05-09 2006-11-15 Orion Diagnostica Oy Sonication of a medium
JP5033791B2 (ja) 2005-05-23 2012-09-26 ファディア・アクチボラグ 二段階側流分析法および装置
EP1922332A2 (en) 2005-09-09 2008-05-21 The University Of Chicago Methods and compositions for diagnosis and immunotherapy of pollen allergy
WO2007053837A1 (en) 2005-10-31 2007-05-10 Invitrogen Corporation An immunosorbent assay support and method of use
US7521577B2 (en) 2006-01-12 2009-04-21 Molecular Probes, Inc. Heavy metal binding compounds and their method of use
US7439014B2 (en) * 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US7727723B2 (en) 2006-04-18 2010-06-01 Advanced Liquid Logic, Inc. Droplet-based pyrosequencing
EP2016189B1 (en) * 2006-04-18 2012-01-25 Advanced Liquid Logic, Inc. Droplet-based pyrosequencing
US7799534B2 (en) 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
ATE540750T1 (de) * 2006-05-11 2012-01-15 Raindance Technologies Inc Mikrofluidische vorrichtung und verfahren
EP3034083B1 (en) 2006-09-21 2020-12-09 University of Rochester Antisense oligonucleotides for use in treating myotonic dystrophy
US7674629B2 (en) 2007-03-15 2010-03-09 Saint Louis University Method for improving chemiluminescent signal
US7906293B2 (en) 2007-04-09 2011-03-15 Abbott Laboratories Acridinium phenyl esters useful in the analysis of biological
JP2010528285A (ja) 2007-05-23 2010-08-19 ベンタナ・メデイカル・システムズ・インコーポレーテツド 免疫組織化学およびinsituハイブリダーゼーションのためのポリマー担体
WO2009025616A1 (en) 2007-08-22 2009-02-26 Phadia Ab Read-out method and apparatus
ES2447875T3 (es) 2007-10-02 2014-03-13 Theranos, Inc. Dispositivos modulares para punto de cuidados y usos de los mismos
US20100075374A1 (en) 2007-11-08 2010-03-25 Ambergen, Inc. Methods for capturing nascent proteins
US7842475B2 (en) 2008-01-08 2010-11-30 Siemens Healthcare Diagnostics Inc. Stabilization of solid support assay reagents
EP2255308A4 (en) 2008-02-08 2015-07-22 Phadia Ab METHOD, PROGRAM PRODUCT AND SYSTEM FOR ASSISTING CLINICAL DECISION
CN101514991A (zh) * 2008-02-19 2009-08-26 北京科美东雅生物技术有限公司 甲胎蛋白磁微粒化学发光免疫分析测定试剂盒及其制备方法
US9562900B2 (en) * 2008-02-21 2017-02-07 Otc Biotechnologies, Llc Methods and compositions of nucleic acid ligands for detection of foodborne and waterborne pathogens
CN101545913A (zh) * 2008-03-25 2009-09-30 北京科美东雅生物技术有限公司 三碘甲腺原氨酸磁微粒化学发光免疫分析测定试剂盒及其制备方法
EP2277044B1 (en) 2008-05-13 2015-06-17 Genentech, Inc. Analysis of antibody drug conjugates by bead-based affinity capture and mass spectrometry
CA2735543C (en) 2008-09-02 2017-05-02 Alison Jane Basile Method for detection of antigen-specific antibodies in biological samples
CN102292637B (zh) 2008-11-21 2015-08-05 法蒂亚公司 用于检测或监测急性肾损伤的方法、装置和试剂盒
FI20095061A0 (fi) * 2009-01-26 2009-01-26 Wallac Oy Optisen mittauslaitteen runkomoduuli
US20110275095A1 (en) * 2009-01-29 2011-11-10 Siemens Healthcare Diagnostics Inc. Microarrays for Allergen-Specific IgE
US8846414B2 (en) * 2009-09-29 2014-09-30 Advanced Liquid Logic, Inc. Detection of cardiac markers on a droplet actuator
CN101696973A (zh) * 2009-10-30 2010-04-21 深圳市博卡生物技术有限公司 一种过敏原特异性IgE抗体免疫分析检测试剂盒及其制备方法
EP3151015A1 (en) * 2010-11-15 2017-04-05 F. Hoffmann-La Roche AG Instrument and method for the automated thermal treatment of liquid samples
CN201897571U (zh) * 2010-11-23 2011-07-13 天津陆海石油设备系统工程有限责任公司 加装保护壳的石油定量荧光仪用比色皿支架
CN102478571A (zh) * 2010-11-23 2012-05-30 南京神州英诺华医疗科技有限公司 一种新的过敏原体外诊断实验方法及其装置
US8658613B2 (en) * 2010-11-30 2014-02-25 Otc Biotechnologies, Llc Methods and compositions of nucleic acid ligands for detection of clinical analytes related to human health
JP5980127B2 (ja) * 2011-02-15 2016-08-31 協和メデックス株式会社 ストレプトアビジン結合磁性粒子及びその製造方法
EP3933384A1 (en) 2013-03-15 2022-01-05 Hycor Biomedical, LLC Device and associated method for performing luminescence and fluorescence measurements of a sample
EP3325965B1 (en) 2015-07-23 2022-02-09 Hycor Biomedical, Inc. On-board kitting
WO2017120241A1 (en) 2016-01-07 2017-07-13 Applied Materials, Inc. Atomic layer etching system with remote plasma source and dc electrode
TW201832726A (zh) 2016-11-01 2018-09-16 美商海科生醫有限責任公司 可基於輸入數據建議檢測之免疫檢測系統

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1054250A1 (en) * 1999-01-25 2000-11-22 Laboratory of Molecular Biophotonics Pipette adaptor, pipette for absorbance measurement, tip, and method and apparatus for absorbance measurement

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