IT202200010064A1 - Dispositivo e metodo per il rilevamento di biomolecole - Google Patents

Dispositivo e metodo per il rilevamento di biomolecole Download PDF

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Publication number
IT202200010064A1
IT202200010064A1 IT102022000010064A IT202200010064A IT202200010064A1 IT 202200010064 A1 IT202200010064 A1 IT 202200010064A1 IT 102022000010064 A IT102022000010064 A IT 102022000010064A IT 202200010064 A IT202200010064 A IT 202200010064A IT 202200010064 A1 IT202200010064 A1 IT 202200010064A1
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IT
Italy
Prior art keywords
biomolecules
detection
Prior art date
Application number
IT102022000010064A
Other languages
English (en)
Inventor
Alfredo Maglione
Simone Detassis
Cristina Ress
Marco Lutteri
Original Assignee
Optoelettronica Italia S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optoelettronica Italia S R L filed Critical Optoelettronica Italia S R L
Priority to IT102022000010064A priority Critical patent/IT202200010064A1/it
Priority to EP23173727.1A priority patent/EP4279904A1/en
Priority to US18/197,793 priority patent/US20240142442A1/en
Publication of IT202200010064A1 publication Critical patent/IT202200010064A1/it

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
IT102022000010064A 2022-05-16 2022-05-16 Dispositivo e metodo per il rilevamento di biomolecole IT202200010064A1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT102022000010064A IT202200010064A1 (it) 2022-05-16 2022-05-16 Dispositivo e metodo per il rilevamento di biomolecole
EP23173727.1A EP4279904A1 (en) 2022-05-16 2023-05-16 Device and method for deteting biomolecules
US18/197,793 US20240142442A1 (en) 2022-05-16 2023-05-16 Device and method for detecting biomolecules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102022000010064A IT202200010064A1 (it) 2022-05-16 2022-05-16 Dispositivo e metodo per il rilevamento di biomolecole

Publications (1)

Publication Number Publication Date
IT202200010064A1 true IT202200010064A1 (it) 2023-11-16

Family

ID=83081024

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102022000010064A IT202200010064A1 (it) 2022-05-16 2022-05-16 Dispositivo e metodo per il rilevamento di biomolecole

Country Status (3)

Country Link
US (1) US20240142442A1 (it)
EP (1) EP4279904A1 (it)
IT (1) IT202200010064A1 (it)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939021A (en) * 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
EP2195459A2 (en) 2007-09-19 2010-06-16 University Court of the University of Edinburgh Nucleobase characterisation
WO2014145581A1 (en) * 2013-03-15 2014-09-18 Hycor Biomedical, Inc. Automated immunoanalyzer system for performing diagnostic assays for allergies and autoimmune diseases
US10900078B2 (en) * 2019-03-14 2021-01-26 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939021A (en) * 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
EP2195459A2 (en) 2007-09-19 2010-06-16 University Court of the University of Edinburgh Nucleobase characterisation
WO2014145581A1 (en) * 2013-03-15 2014-09-18 Hycor Biomedical, Inc. Automated immunoanalyzer system for performing diagnostic assays for allergies and autoimmune diseases
US10900078B2 (en) * 2019-03-14 2021-01-26 Ultima Genomics, Inc. Methods, devices, and systems for analyte detection and analysis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BEDNAR RILEY M ET AL: "S-1 Supporting Information for Immobilization of Proteins with Controlled Load and Orientation This PDF file includes: Materials and Methods Supplementary Text Schemes S1-3 Figures S1-24 Tables S1-4 References 54-90", 9 October 2019 (2019-10-09), XP093009844, Retrieved from the Internet <URL:https://pubs.acs.org/doi/abs/10.1021/acsami.9b12746> [retrieved on 20221220], DOI: 10.1021/acsami.9b12746 *
BEDNAR RILEY M. ET AL: "Immobilization of Proteins with Controlled Load and Orientation", APPLIED MATERIALS & INTERFACES, vol. 11, no. 40, 17 September 2019 (2019-09-17), US, pages 36391 - 36398, XP055939670, ISSN: 1944-8244, DOI: 10.1021/acsami.9b12746 *
ZORDAN MICHAEL D ET AL: "Detection of pathogenic E. coli O157:H7 by a hybrid microfluidic SPR and molecular imaging cytometry device", CYTOMETRY A, WILEY-LISS, vol. 75, no. 2, 1 February 2009 (2009-02-01), pages 155 - 162, XP009115487, ISSN: 1552-4922, [retrieved on 20081205], DOI: 10.1002/CYTO.A.20692 *

Also Published As

Publication number Publication date
EP4279904A1 (en) 2023-11-22
US20240142442A1 (en) 2024-05-02

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