AU2014228990B2 - Rapid disperse dosage form containing levetiracetam - Google Patents

Rapid disperse dosage form containing levetiracetam Download PDF

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Publication number
AU2014228990B2
AU2014228990B2 AU2014228990A AU2014228990A AU2014228990B2 AU 2014228990 B2 AU2014228990 B2 AU 2014228990B2 AU 2014228990 A AU2014228990 A AU 2014228990A AU 2014228990 A AU2014228990 A AU 2014228990A AU 2014228990 B2 AU2014228990 B2 AU 2014228990B2
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AU
Australia
Prior art keywords
dosage form
matrix
lev
less
bound
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Application number
AU2014228990A
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English (en)
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AU2014228990A1 (en
Inventor
Norman COYLE
Jules Jacob
Nemichand B. Jain
Donald C. Monkhouse
Henry L. Surprenant
Thomas G. West
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Aprecia Pharmaceuticals LLC
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Aprecia Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of AU2014228990A1 publication Critical patent/AU2014228990A1/en
Application granted granted Critical
Publication of AU2014228990B2 publication Critical patent/AU2014228990B2/en
Priority to AU2017202752A priority Critical patent/AU2017202752B2/en
Assigned to Aprecia Pharmaceuticals LLC reassignment Aprecia Pharmaceuticals LLC Request for Assignment Assignors: APRECIA PHARMACEUTICALS COMPANY
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2014228990A 2013-03-15 2014-03-14 Rapid disperse dosage form containing levetiracetam Active AU2014228990B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2017202752A AU2017202752B2 (en) 2013-03-15 2017-04-26 Rapid disperse dosage form containing levetiracetam

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361791444P 2013-03-15 2013-03-15
US61/791,444 2013-03-15
PCT/US2014/028954 WO2014144512A1 (en) 2013-03-15 2014-03-14 Rapid disperse dosage form containing levetiracetam

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2017202752A Division AU2017202752B2 (en) 2013-03-15 2017-04-26 Rapid disperse dosage form containing levetiracetam

Publications (2)

Publication Number Publication Date
AU2014228990A1 AU2014228990A1 (en) 2015-10-08
AU2014228990B2 true AU2014228990B2 (en) 2017-02-02

Family

ID=51537722

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2014228990A Active AU2014228990B2 (en) 2013-03-15 2014-03-14 Rapid disperse dosage form containing levetiracetam
AU2017202752A Active AU2017202752B2 (en) 2013-03-15 2017-04-26 Rapid disperse dosage form containing levetiracetam

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2017202752A Active AU2017202752B2 (en) 2013-03-15 2017-04-26 Rapid disperse dosage form containing levetiracetam

Country Status (10)

Country Link
US (2) US20220211668A1 (OSRAM)
EP (2) EP3431141B1 (OSRAM)
JP (3) JP6170234B2 (OSRAM)
CN (2) CN109908355B (OSRAM)
AU (2) AU2014228990B2 (OSRAM)
CA (1) CA2906029C (OSRAM)
ES (2) ES2688880T3 (OSRAM)
HK (1) HK1216513A1 (OSRAM)
MX (1) MX365513B (OSRAM)
WO (1) WO2014144512A1 (OSRAM)

Families Citing this family (16)

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CN109908355B (zh) 2013-03-15 2022-11-15 阿普雷奇亚制药有限责任公司 包含左乙拉西坦的快速分散剂型
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
US10653622B1 (en) 2015-04-13 2020-05-19 Pharmacoustics Technologies LLC Individualized solid dosage products and a system and method for the globally integrated pharmaceutical manufacturing and its monitoring thereof
AU2016272089B2 (en) 2015-06-03 2021-02-18 Triastek, Inc. Dosage forms and use thereof
AU2017322186A1 (en) 2016-09-09 2019-05-02 Merck Patent Gmbh Process for the manufacture of a solid pharmaceutical adminstration form
JP7191385B2 (ja) 2017-01-26 2022-12-19 トリアステック インコーポレイテッド 特定の胃腸部位での制御放出の剤形
WO2018156141A1 (en) 2017-02-24 2018-08-30 Hewlett-Packard Development Company, L.P. Three-dimensional (3d) printing a pharmaceutical tablet
KR102636273B1 (ko) 2017-03-08 2024-02-16 신알엑스 파마, 엘엘씨 플로로글루시놀 및 트리메틸플로로글루시놀의 제약 제제
US12142770B2 (en) 2017-03-31 2024-11-12 Nippon Steel Chemical & Material Co., Ltd. Carbon material for use as catalyst carrier of polymer electrolyte fuel cell and method of producing the same
JP6653931B2 (ja) * 2017-06-16 2020-02-26 丸石製薬株式会社 レベチラセタム含有ゲル経口医薬組成物
CN111698983B (zh) 2018-01-09 2022-10-18 南京三迭纪医药科技有限公司 一种包含固定剂量adhd非兴奋剂和adhd兴奋剂的复方口服药物剂型
JP7264711B2 (ja) * 2019-04-26 2023-04-25 東和薬品株式会社 レベチラセタム含有医薬組成物の製造方法
JP2022535390A (ja) 2019-05-31 2022-08-08 ディヘシス デジタル ヘルス システムズ ゲーエムベーハー 医薬品剤形およびその製造方法
TWI734309B (zh) * 2019-12-19 2021-07-21 水星生醫股份有限公司 滲透性噴塗製作藥錠裝置
CN111840243B (zh) * 2020-07-30 2021-11-30 中国人民解放军军事科学院军事医学研究院 一种左乙拉西坦3d打印制剂及其制备方法
CN113599362A (zh) * 2021-01-15 2021-11-05 中国人民解放军军事科学院军事医学研究院 一种3d打印制剂及其制备方法和其应用

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