AU2013233943B2 - Novel methods and compositions for treatment of disease - Google Patents

Novel methods and compositions for treatment of disease Download PDF

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Publication number
AU2013233943B2
AU2013233943B2 AU2013233943A AU2013233943A AU2013233943B2 AU 2013233943 B2 AU2013233943 B2 AU 2013233943B2 AU 2013233943 A AU2013233943 A AU 2013233943A AU 2013233943 A AU2013233943 A AU 2013233943A AU 2013233943 B2 AU2013233943 B2 AU 2013233943B2
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Australia
Prior art keywords
extract
extracts
herbal
alcohol
compositions
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AU2013233943A
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AU2013233943A1 (en
Inventor
Gabriel Jay NUSSBAUM
Amy Debra ROSENBLUH
Avner Rotman
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Izun Pharmaceuticals Corp
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Izun Pharmaceuticals Corp
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Assigned to IZUN PHARMACEUTICALS CORP reassignment IZUN PHARMACEUTICALS CORP Amend patent request/document other than specification (104) Assignors: IZUN PHARMACEUTICALS LTD.
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D11/00Solvent extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
AU2013233943A 2012-03-14 2013-03-13 Novel methods and compositions for treatment of disease Active AU2013233943B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261610480P 2012-03-14 2012-03-14
US61/610,480 2012-03-14
PCT/IB2013/051970 WO2013136270A1 (en) 2012-03-14 2013-03-13 Novel methods and compositions for treatment of disease

Publications (2)

Publication Number Publication Date
AU2013233943A1 AU2013233943A1 (en) 2014-09-25
AU2013233943B2 true AU2013233943B2 (en) 2017-10-19

Family

ID=48190560

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013233943A Active AU2013233943B2 (en) 2012-03-14 2013-03-13 Novel methods and compositions for treatment of disease

Country Status (13)

Country Link
US (2) US20150064291A1 (https=)
EP (1) EP2825185B1 (https=)
JP (1) JP6410355B2 (https=)
KR (1) KR102168118B1 (https=)
CN (1) CN104394875B (https=)
AU (1) AU2013233943B2 (https=)
BR (1) BR112014022694B1 (https=)
CA (1) CA2867260C (https=)
ES (1) ES3014157T3 (https=)
IL (1) IL234606B (https=)
IN (1) IN2014DN08440A (https=)
RU (1) RU2683774C2 (https=)
WO (1) WO2013136270A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3057601A4 (en) 2013-10-14 2017-06-21 Izun Pharmaceuticals Corp. Methods for treatment of m-tor inhibitor-associated stomatitis
KR101649450B1 (ko) * 2015-08-19 2016-08-18 이상철 피부 상처 치료조성물
AU2016326742B2 (en) * 2015-09-24 2022-04-28 Caris Science, Inc. Method, apparatus, and computer program product for analyzing biological data
KR101751486B1 (ko) * 2016-03-02 2017-06-28 광주과학기술원 BKCa 채널 활성화용 조성물
JP7121944B2 (ja) * 2018-05-07 2022-08-19 国立大学法人信州大学 ナノ繊維及びその製造方法
IL262744B (en) * 2018-11-04 2020-03-31 Izun Pharmaceuticals Corp Hydrogel compositions comprising plant extracts
RU2716501C1 (ru) * 2019-03-11 2020-03-12 Тамара Владимировна Пономаренко Композиция для профилактики и лечения воспалительных заболеваний полости рта
IL302462A (en) * 2020-10-28 2023-06-01 Izun Pharmaceuticals Corp Treatment of oral mucositis
KR102613837B1 (ko) * 2021-11-25 2023-12-15 주식회사 젠트리바이오 천연물질 추출물의 혼합물을 주성분으로 하는 항산화 및 항염증 효능을 갖는 조성물 및 그 제조방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040151789A1 (en) * 2001-05-23 2004-08-05 Levine William Z. Herbal compositions for the treatment of mucosal lesions
WO2009078022A2 (en) * 2007-12-17 2009-06-25 Izun Pharmaceuticals Corporation Synergistic combinations of growth factors with herbal compositions for the enhancement of tissue repair

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU931188A1 (ru) * 1980-04-22 1982-05-30 Запорожский государственный медицинский институт Способ получени фенольных соединений,обладающих противовоспалительным действием
JP2001048798A (ja) * 1999-08-06 2001-02-20 Sakamoto Yakuhin Kogyo Co Ltd 抗菌剤
CN1137115C (zh) * 2001-11-24 2004-02-04 广东梅州市梅雁螺旋藻高科技研究所 从柚皮中提取黄酮的方法
ITMI20021691A1 (it) * 2002-07-30 2004-01-30 Indena Spa Estratti di echinacea angustifolia
JP2005179252A (ja) * 2003-12-19 2005-07-07 Taiyo Kagaku Co Ltd 血栓形成抑制剤
US20060018867A1 (en) * 2004-05-12 2006-01-26 Ichimaru Pharcos Co., Ltd Cosmetic composition and production thereof
WO2006024284A2 (de) * 2004-09-01 2006-03-09 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Atrium patch
WO2007149902A1 (en) * 2006-06-20 2007-12-27 Izun Pharmaceuticals Corporation Anti-inflammatory dissolvable film
ES2605794T3 (es) * 2006-07-20 2017-03-16 Izun Pharmaceuticals Corporation Película, parche o formulación sólida adhesiva que comprende Sambucus nigra, Centella asiatica y sal de 1-alquilpiridinio para el tratamiento de tejidos mucosos
KR101660246B1 (ko) * 2008-07-22 2016-09-27 이준 파마슈티컬스, 인코포레이티드 국소 항염증 조합물
US8853774B2 (en) 2012-11-30 2014-10-07 Infineon Technologies Ag Semiconductor device including trenches and method of manufacturing a semiconductor device
WO2020100115A1 (en) 2018-11-16 2020-05-22 Ses Holdings Pte. Ltd. Processes for removing reactive solvent from lithium bis(fluorosulfonyl)imide (lifsi) using organic solvents that are stable toward anodes in lithium-ion and lithium-metal batteries

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040151789A1 (en) * 2001-05-23 2004-08-05 Levine William Z. Herbal compositions for the treatment of mucosal lesions
WO2009078022A2 (en) * 2007-12-17 2009-06-25 Izun Pharmaceuticals Corporation Synergistic combinations of growth factors with herbal compositions for the enhancement of tissue repair

Also Published As

Publication number Publication date
US12059445B2 (en) 2024-08-13
KR20140138894A (ko) 2014-12-04
IL234606A0 (en) 2014-11-30
IN2014DN08440A (https=) 2015-05-08
EP2825185B1 (en) 2025-01-08
ES3014157T3 (en) 2025-04-21
RU2014136776A (ru) 2016-05-10
RU2683774C2 (ru) 2019-04-02
CN104394875A (zh) 2015-03-04
EP2825185A1 (en) 2015-01-21
JP2015514057A (ja) 2015-05-18
JP6410355B2 (ja) 2018-10-24
BR112014022694A2 (en) 2018-02-27
CN104394875B (zh) 2018-12-04
AU2013233943A1 (en) 2014-09-25
CA2867260C (en) 2021-10-05
US20210128661A1 (en) 2021-05-06
IL234606B (en) 2021-04-29
US20150064291A1 (en) 2015-03-05
EP2825185C0 (en) 2025-01-08
BR112014022694B1 (pt) 2021-03-09
CA2867260A1 (en) 2013-09-19
KR102168118B1 (ko) 2020-10-21
WO2013136270A1 (en) 2013-09-19

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