CN104394875B - 用于治疗疾病的新颖的方法和组合物 - Google Patents

用于治疗疾病的新颖的方法和组合物 Download PDF

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Publication number
CN104394875B
CN104394875B CN201380014283.9A CN201380014283A CN104394875B CN 104394875 B CN104394875 B CN 104394875B CN 201380014283 A CN201380014283 A CN 201380014283A CN 104394875 B CN104394875 B CN 104394875B
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extract
alcohol
composition
concentration
dried
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Expired - Fee Related
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CN201380014283.9A
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English (en)
Chinese (zh)
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CN104394875A (zh
Inventor
A·D·罗森布鲁
G·J·努斯鲍姆
A·罗特曼
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Izun Pharmaceuticals Ltd
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Izun Pharmaceuticals Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D11/00Solvent extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
CN201380014283.9A 2012-03-14 2013-03-13 用于治疗疾病的新颖的方法和组合物 Expired - Fee Related CN104394875B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261610480P 2012-03-14 2012-03-14
US61/610,480 2012-03-14
PCT/IB2013/051970 WO2013136270A1 (en) 2012-03-14 2013-03-13 Novel methods and compositions for treatment of disease

Publications (2)

Publication Number Publication Date
CN104394875A CN104394875A (zh) 2015-03-04
CN104394875B true CN104394875B (zh) 2018-12-04

Family

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CN201380014283.9A Expired - Fee Related CN104394875B (zh) 2012-03-14 2013-03-13 用于治疗疾病的新颖的方法和组合物

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Country Link
US (2) US20150064291A1 (https=)
EP (1) EP2825185B1 (https=)
JP (1) JP6410355B2 (https=)
KR (1) KR102168118B1 (https=)
CN (1) CN104394875B (https=)
AU (1) AU2013233943B2 (https=)
BR (1) BR112014022694B1 (https=)
CA (1) CA2867260C (https=)
ES (1) ES3014157T3 (https=)
IL (1) IL234606B (https=)
IN (1) IN2014DN08440A (https=)
RU (1) RU2683774C2 (https=)
WO (1) WO2013136270A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3057601A4 (en) 2013-10-14 2017-06-21 Izun Pharmaceuticals Corp. Methods for treatment of m-tor inhibitor-associated stomatitis
KR101649450B1 (ko) * 2015-08-19 2016-08-18 이상철 피부 상처 치료조성물
IL258309B2 (en) * 2015-09-24 2023-03-01 Caris Science Inc Method, device and product of computer software for analyzing biological data
KR101751486B1 (ko) * 2016-03-02 2017-06-28 광주과학기술원 BKCa 채널 활성화용 조성물
JP7121944B2 (ja) * 2018-05-07 2022-08-19 国立大学法人信州大学 ナノ繊維及びその製造方法
IL262744B (en) * 2018-11-04 2020-03-31 Izun Pharmaceuticals Corp Hydrogel compositions comprising plant extracts
RU2716501C1 (ru) * 2019-03-11 2020-03-12 Тамара Владимировна Пономаренко Композиция для профилактики и лечения воспалительных заболеваний полости рта
EP4236978A4 (en) 2020-10-28 2024-09-11 Izun Pharmaceuticals Corp. Treatment of oral mucositis
KR102613837B1 (ko) * 2021-11-25 2023-12-15 주식회사 젠트리바이오 천연물질 추출물의 혼합물을 주성분으로 하는 항산화 및 항염증 효능을 갖는 조성물 및 그 제조방법

Citations (3)

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CN1356327A (zh) * 2001-11-24 2002-07-03 广东梅州市梅雁螺旋藻高科技研究所 从柚皮中提取黄酮的方法
WO2009078022A2 (en) * 2007-12-17 2009-06-25 Izun Pharmaceuticals Corporation Synergistic combinations of growth factors with herbal compositions for the enhancement of tissue repair
WO2010011541A2 (en) * 2008-07-22 2010-01-28 Izun Pharmaceuticals, Inc. Topical anti-inflammatory combination

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SU931188A1 (ru) * 1980-04-22 1982-05-30 Запорожский государственный медицинский институт Способ получени фенольных соединений,обладающих противовоспалительным действием
JP2001048798A (ja) * 1999-08-06 2001-02-20 Sakamoto Yakuhin Kogyo Co Ltd 抗菌剤
IL143318A0 (en) * 2001-05-23 2002-04-21 Herbal Synthesis Corp Herbal compositions for the treatment of mucosal lesions
ITMI20021691A1 (it) * 2002-07-30 2004-01-30 Indena Spa Estratti di echinacea angustifolia
JP2005179252A (ja) * 2003-12-19 2005-07-07 Taiyo Kagaku Co Ltd 血栓形成抑制剤
EP1604647B1 (en) * 2004-05-12 2008-05-07 Chisso Corporation Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof
ES2299082T3 (es) * 2004-09-01 2008-05-16 Labtec Gesellschaft Fur Technologische Forschung Und Entwicklung Mbh Parche para cavidades.
KR20090026804A (ko) * 2006-06-20 2009-03-13 이준 파마슈티컬스 코포레이션 항염증 용해 가능한 필름
KR101474809B1 (ko) * 2006-07-20 2014-12-19 이준 파마슈티컬스 코포레이션 필름 전달 린스
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CN1356327A (zh) * 2001-11-24 2002-07-03 广东梅州市梅雁螺旋藻高科技研究所 从柚皮中提取黄酮的方法
WO2009078022A2 (en) * 2007-12-17 2009-06-25 Izun Pharmaceuticals Corporation Synergistic combinations of growth factors with herbal compositions for the enhancement of tissue repair
WO2010011541A2 (en) * 2008-07-22 2010-01-28 Izun Pharmaceuticals, Inc. Topical anti-inflammatory combination

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Publication number Publication date
US20210128661A1 (en) 2021-05-06
BR112014022694A2 (en) 2018-02-27
IL234606B (en) 2021-04-29
US20150064291A1 (en) 2015-03-05
CN104394875A (zh) 2015-03-04
ES3014157T3 (en) 2025-04-21
JP2015514057A (ja) 2015-05-18
WO2013136270A1 (en) 2013-09-19
AU2013233943B2 (en) 2017-10-19
US12059445B2 (en) 2024-08-13
EP2825185A1 (en) 2015-01-21
IL234606A0 (en) 2014-11-30
BR112014022694B1 (pt) 2021-03-09
JP6410355B2 (ja) 2018-10-24
AU2013233943A1 (en) 2014-09-25
RU2014136776A (ru) 2016-05-10
EP2825185C0 (en) 2025-01-08
KR20140138894A (ko) 2014-12-04
CA2867260C (en) 2021-10-05
CA2867260A1 (en) 2013-09-19
RU2683774C2 (ru) 2019-04-02
EP2825185B1 (en) 2025-01-08
IN2014DN08440A (https=) 2015-05-08
KR102168118B1 (ko) 2020-10-21

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