AU2012314536B2 - N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate - Google Patents

N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate Download PDF

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Publication number
AU2012314536B2
AU2012314536B2 AU2012314536A AU2012314536A AU2012314536B2 AU 2012314536 B2 AU2012314536 B2 AU 2012314536B2 AU 2012314536 A AU2012314536 A AU 2012314536A AU 2012314536 A AU2012314536 A AU 2012314536A AU 2012314536 B2 AU2012314536 B2 AU 2012314536B2
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Prior art keywords
methyl
phenyl
pyridinyl
thiazol
aminosulfonyl
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AU2012314536A1 (en
Inventor
Alexander Birkmann
Alfons Grunenberg
Dieter Haag
Birgit Keil
Andreas Lender
Joachim Rehse
Wilfried Schwab
Kurt Vogtli
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Aic316 GmbH
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Aic316 GmbH
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Assigned to AIC316 GMBH reassignment AIC316 GMBH Request for Assignment Assignors: AICURIS GMBH & CO. KG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AU2012314536A 2011-09-26 2012-09-26 N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate Active AU2012314536B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2015260762A AU2015260762B2 (en) 2011-09-26 2015-11-24 N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11007823.5 2011-09-26
EP11007823A EP2573086A1 (en) 2011-09-26 2011-09-26 N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate
PCT/EP2012/068938 WO2013045479A1 (en) 2011-09-26 2012-09-26 N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate

Related Child Applications (1)

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AU2015260762A Division AU2015260762B2 (en) 2011-09-26 2015-11-24 N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate

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AU2012314536A1 AU2012314536A1 (en) 2014-02-06
AU2012314536B2 true AU2012314536B2 (en) 2016-01-14

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AU2012314536A Active AU2012314536B2 (en) 2011-09-26 2012-09-26 N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate
AU2015260762A Active AU2015260762B2 (en) 2011-09-26 2015-11-24 N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate

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US (1) US9340535B2 (enExample)
EP (3) EP2573086A1 (enExample)
JP (2) JP6161614B2 (enExample)
KR (4) KR20170055565A (enExample)
CN (2) CN103842359B (enExample)
AR (3) AR088043A1 (enExample)
AU (2) AU2012314536B2 (enExample)
BR (1) BR112014003245B1 (enExample)
CA (1) CA2791142C (enExample)
CL (1) CL2014000149A1 (enExample)
DK (2) DK2598501T3 (enExample)
ES (2) ES2466221T3 (enExample)
HK (1) HK1220978A1 (enExample)
HR (1) HRP20140351T1 (enExample)
IL (2) IL230152A (enExample)
IN (1) IN2014DN01993A (enExample)
JO (2) JO3037B1 (enExample)
MX (2) MX371088B (enExample)
MY (2) MY190878A (enExample)
PE (1) PE20141148A1 (enExample)
PH (2) PH12014500567A1 (enExample)
PL (2) PL2602258T3 (enExample)
PT (1) PT2598501E (enExample)
RU (2) RU2620604C2 (enExample)
SG (1) SG10201407430TA (enExample)
TW (2) TWI567070B (enExample)
UA (2) UA115317C2 (enExample)
WO (1) WO2013045479A1 (enExample)
ZA (2) ZA201401773B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2573086A1 (en) * 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate
EP2573085A1 (en) 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(aminosulfonyl)-4methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl] acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range
GEP20207128B (en) * 2016-04-06 2020-07-10 Molecules Gm Innovative Aminothiazole derivatives useful as antiviral agents
JP6978501B2 (ja) * 2016-11-28 2021-12-08 アイクリス ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト Ｎ−［５−（アミノスルホニル）−４−メチル−１，３−チアゾール−２−イル］−ｎ−メチル−２−［４−（２−ピリジニル）−フェニル］−アセトアミド遊離塩基半水和物、製造方法およびその用途
UY37498A (es) 2016-11-28 2018-06-29 Aicuris Anti Infective Cures Gmbh Una sal maleato de la base libre de n-[5-(aminosulfonil)-4-20 metil-1,3-tiazol-2-il]-n-metil-2-[4-(2-piridinil)-fenil]-acetamida, formulaciones farmacéuticas, métodos de fabricación y usos de la misma
WO2018095576A1 (en) * 2016-11-28 2018-05-31 Aicuris Anti-Infective Cures Gmbh Topical pharmaceutical formulation comprising n-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)-phenyl]-acetamide
KR102335327B1 (ko) 2017-04-28 2021-12-03 현대자동차 주식회사 수냉식 이지알 쿨러
CN110831577B (zh) * 2017-06-28 2023-11-28 艾库里斯有限及两合公司 包含抗病毒化合物的阴道内施用型装置
KR102708082B1 (ko) 2017-10-05 2024-09-19 이노베이티브 몰리큘스 게엠베하 항바이러스 화합물로서 치환된 티아졸의 거울상 이성질체
US11964969B2 (en) 2018-07-06 2024-04-23 Phaeno Therapeutics Co., Ltd Crystal forms of thiazole compound and application thereof
US12383508B2 (en) * 2018-09-19 2025-08-12 Modernatx, Inc. High-purity peg lipids and uses thereof
TW202038947A (zh) 2018-11-28 2020-11-01 德商創新分子有限責任公司 在與溶瘤病毒之組合療法中治療癌症的解旋酶引子酶抑制劑
CA3168721A1 (en) * 2020-03-26 2021-09-30 Jessica Redmer Ophthalmic formulation comprising n-[5-(aminosulfonyl)-4-methyl-1,3- thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamide hemihydrate
EP4581031A1 (en) 2022-08-29 2025-07-09 Assembly Biosciences, Inc. A novel crystalline form of pritelivir
CA3265860A1 (en) 2022-08-29 2024-03-07 Assembly Biosciences, Inc. Pharmaceutical compositions against the herpes virus
WO2024047506A1 (en) 2022-08-29 2024-03-07 Assembly Biosciences, Inc. A novel crystalline form of pritelivir

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006103011A1 (de) * 2005-03-30 2006-10-05 Aicuris Gmbh & Co. Kg Pharmazeutische zubereitung von n-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamid

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DOP2000000109A (es) 1999-12-23 2002-08-30 Gerald Kleymann Derivados de tiazolilamida
DE10129716A1 (de) * 2001-06-22 2003-01-02 Bayer Ag Kombinationspräparate zur Herpes-Behandlung
DE10129714A1 (de) * 2001-06-22 2003-01-02 Bayer Ag Topische Anwendung von Thiazolylamiden
DE10129717A1 (de) * 2001-06-22 2003-01-02 Bayer Ag Kombinationspräparate zur Herpes-Behandlung
DE10131128A1 (de) * 2001-06-28 2003-01-16 Bayer Ag Sekundäre Sulfonamide
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
JP2007314516A (ja) * 2006-04-25 2007-12-06 Daiichi Sankyo Co Ltd ２以上の置換基を有するベンゼン化合物を含有する医薬
MX2008015638A (es) * 2006-06-09 2009-01-09 Icos Corp Acidos fenil aceticos sustituidos como antagonistas de dp-2.
AR070127A1 (es) * 2008-01-11 2010-03-17 Novartis Ag Pirrolo - pirimidinas y pirrolo -piridinas
UA103918C2 (en) * 2009-03-02 2013-12-10 Айерем Элелси N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators
EP2573085A1 (en) * 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(aminosulfonyl)-4methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl] acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range
EP2573086A1 (en) * 2011-09-26 2013-03-27 AiCuris GmbH & Co. KG N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006103011A1 (de) * 2005-03-30 2006-10-05 Aicuris Gmbh & Co. Kg Pharmazeutische zubereitung von n-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-n-methyl-2-[4-(2-pyridinyl)phenyl]acetamid

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CA2791142C (en) 2017-08-01
AU2015260762A1 (en) 2016-02-04
EP2598501B1 (en) 2014-03-12
CL2014000149A1 (es) 2014-09-05
NZ718867A (en) 2016-05-27
PH12014500567A1 (en) 2014-04-14
JO3037B1 (ar) 2016-09-05
JO3734B1 (ar) 2021-01-31
KR101768295B1 (ko) 2017-08-14
ES2466221T8 (es) 2016-09-13
JP6161614B2 (ja) 2017-07-12
EP2602258B1 (en) 2014-03-19
CN105541829A (zh) 2016-05-04
ES2466221T3 (es) 2014-06-09
TWI532739B (zh) 2016-05-11
US20140221433A1 (en) 2014-08-07
UA119574C2 (uk) 2019-07-10
WO2013045479A1 (en) 2013-04-04
HK1220978A1 (zh) 2017-05-19
EP2573086A1 (en) 2013-03-27
UA115317C2 (uk) 2017-10-25
PE20141148A1 (es) 2014-09-15
PH12015502801A1 (en) 2016-10-03
CN103842359A (zh) 2014-06-04
MY185063A (en) 2021-04-30
RU2620604C2 (ru) 2017-05-29
EP2602258B8 (en) 2016-09-28
AR088043A1 (es) 2014-05-07
DK2602258T3 (da) 2014-04-22
MY190878A (en) 2022-05-13
BR112014003245A2 (pt) 2017-03-01
IL230152A (en) 2015-04-30
DK2598501T3 (da) 2014-04-22
PT2598501E (pt) 2014-06-25
RU2014107430A (ru) 2015-11-10
CA2791142A1 (en) 2013-03-26
ES2462492T3 (es) 2014-05-23
MX2014003389A (es) 2014-07-09
PH12015502801B1 (en) 2016-10-03
EP2602258A1 (en) 2013-06-12
CN103842359B (zh) 2016-05-25
KR20180088530A (ko) 2018-08-03
AR116394A2 (es) 2021-05-05
KR20170055565A (ko) 2017-05-19
AU2015260762B2 (en) 2016-06-09
PL2598501T3 (pl) 2014-08-29
TW201625603A (zh) 2016-07-16
AR120291A2 (es) 2022-02-09
AU2012314536A1 (en) 2014-02-06
KR20140066704A (ko) 2014-06-02
RU2669388C1 (ru) 2018-10-11
IL234405A (en) 2015-04-30
ZA201408734B (en) 2016-08-31
US9340535B2 (en) 2016-05-17
IN2014DN01993A (enExample) 2015-05-15
BR112014003245B1 (pt) 2021-11-09
NZ621615A (en) 2016-04-29
HRP20140351T1 (hr) 2014-07-04
JP2017114859A (ja) 2017-06-29
JP2014528948A (ja) 2014-10-30
MX371088B (es) 2020-01-16
TWI567070B (zh) 2017-01-21
KR20190104249A (ko) 2019-09-06
MX338736B (es) 2016-04-29
TW201317234A (zh) 2013-05-01
ZA201401773B (en) 2015-12-23
JP6353022B2 (ja) 2018-07-04
EP2598501A1 (en) 2013-06-05
PL2602258T3 (pl) 2014-08-29
SG10201407430TA (en) 2014-12-30

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