AU2011324870B2 - pan-HER antibody composition - Google Patents

pan-HER antibody composition Download PDF

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Publication number
AU2011324870B2
AU2011324870B2 AU2011324870A AU2011324870A AU2011324870B2 AU 2011324870 B2 AU2011324870 B2 AU 2011324870B2 AU 2011324870 A AU2011324870 A AU 2011324870A AU 2011324870 A AU2011324870 A AU 2011324870A AU 2011324870 B2 AU2011324870 B2 AU 2011324870B2
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AU
Australia
Prior art keywords
antibody
antibodies
egfr
her2
her3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2011324870A
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English (en)
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AU2011324870A1 (en
Inventor
Ida K. Christensen
Helle Jacobsen
Michael Kragh
Johan Lantto
Mikkel Wandahl Pedersen
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Symphogen AS
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Symphogen AS
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Publication date
Application filed by Symphogen AS filed Critical Symphogen AS
Publication of AU2011324870A1 publication Critical patent/AU2011324870A1/en
Application granted granted Critical
Publication of AU2011324870B2 publication Critical patent/AU2011324870B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2011324870A 2010-11-01 2011-10-31 pan-HER antibody composition Ceased AU2011324870B2 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US40878210P 2010-11-01 2010-11-01
US61/408,782 2010-11-01
DKPA201000988 2010-11-01
DKPA201000988 2010-11-01
DKPA201100672 2011-09-05
DKPA201100672 2011-09-05
US201161531407P 2011-09-06 2011-09-06
US61/531,407 2011-09-06
PCT/IB2011/054834 WO2012059857A2 (en) 2010-11-01 2011-10-31 Pan-her antibody composition

Publications (2)

Publication Number Publication Date
AU2011324870A1 AU2011324870A1 (en) 2013-01-31
AU2011324870B2 true AU2011324870B2 (en) 2015-01-29

Family

ID=59014867

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2011324870A Ceased AU2011324870B2 (en) 2010-11-01 2011-10-31 pan-HER antibody composition
AU2011324871A Ceased AU2011324871B2 (en) 2010-11-01 2011-10-31 Anti-HER3 antibodies and compositions

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2011324871A Ceased AU2011324871B2 (en) 2010-11-01 2011-10-31 Anti-HER3 antibodies and compositions

Country Status (13)

Country Link
US (1) US9217039B2 (https=)
EP (3) EP2635604B1 (https=)
JP (2) JP6033783B2 (https=)
KR (2) KR101773120B1 (https=)
AU (2) AU2011324870B2 (https=)
CA (2) CA2816520C (https=)
DK (1) DK2635604T3 (https=)
ES (2) ES2692379T3 (https=)
IL (2) IL225954B (https=)
MX (2) MX348637B (https=)
PL (1) PL2635604T3 (https=)
TW (1) TW201231066A (https=)
WO (2) WO2012059857A2 (https=)

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US10450376B2 (en) 2014-09-16 2019-10-22 Symphogen A/S Anti-MET antibodies and compositions
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US11359024B2 (en) * 2018-09-07 2022-06-14 Pfizer Inc. Anti-AVB8 antibodies and compositions and uses thereof
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Also Published As

Publication number Publication date
MX348637B (es) 2017-06-22
JP2014503189A (ja) 2014-02-13
CA2816520C (en) 2017-11-21
KR101773120B1 (ko) 2017-08-30
CA2816519A1 (en) 2012-05-10
CA2816519C (en) 2019-01-15
EP2635605A4 (en) 2014-10-22
PL2635604T3 (pl) 2017-09-29
ES2692379T3 (es) 2018-12-03
KR101862832B1 (ko) 2018-05-30
EP2635604B1 (en) 2016-11-30
IL225954A0 (en) 2013-07-31
TW201231066A (en) 2012-08-01
IL225953A0 (en) 2013-07-31
JP6033783B2 (ja) 2016-11-30
WO2012059857A3 (en) 2012-07-19
AU2011324871A1 (en) 2013-05-09
CA2816520A1 (en) 2012-05-10
US9217039B2 (en) 2015-12-22
EP2635605A1 (en) 2013-09-11
US20130287684A1 (en) 2013-10-31
WO2012059858A1 (en) 2012-05-10
MX2013004899A (es) 2013-07-15
JP2014503188A (ja) 2014-02-13
KR20140026336A (ko) 2014-03-05
EP2635605B1 (en) 2018-07-25
AU2011324870A1 (en) 2013-01-31
MX347981B (es) 2017-05-22
KR20140026337A (ko) 2014-03-05
JP6186277B2 (ja) 2017-08-23
EP3156421A1 (en) 2017-04-19
AU2011324871B2 (en) 2016-05-19
EP3156421B1 (en) 2018-06-06
WO2012059857A2 (en) 2012-05-10
IL225954B (en) 2018-05-31
MX2013004897A (es) 2013-07-15
DK2635604T3 (en) 2017-02-27
EP2635604A2 (en) 2013-09-11
ES2616961T3 (es) 2017-06-14

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