AU2010324739B2 - Antibodies to IL-6 and use thereof - Google Patents

Antibodies to IL-6 and use thereof Download PDF

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Publication number
AU2010324739B2
AU2010324739B2 AU2010324739A AU2010324739A AU2010324739B2 AU 2010324739 B2 AU2010324739 B2 AU 2010324739B2 AU 2010324739 A AU2010324739 A AU 2010324739A AU 2010324739 A AU2010324739 A AU 2010324739A AU 2010324739 B2 AU2010324739 B2 AU 2010324739B2
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Australia
Prior art keywords
antibody
seq
patient
cancer
polypeptide
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AU2010324739A
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AU2010324739A1 (en
Inventor
Ben Dutzar
Leon Garcia-Martinez
Anne Elisabeth Carvalho Jensen
Brian Kovacevich
John Latham
Mark Litton
Katie Olson
Randall Schatzman
Jeffrey T. L. Smith
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H Lundbeck AS
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H Lundbeck AS
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Priority claimed from US12/624,816 external-priority patent/US8337847B2/en
Priority claimed from US12/624,778 external-priority patent/US9452227B2/en
Priority claimed from US12/624,965 external-priority patent/US8420089B2/en
Priority claimed from US12/624,830 external-priority patent/US8277804B2/en
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of AU2010324739A1 publication Critical patent/AU2010324739A1/en
Priority to AU2013203976A priority Critical patent/AU2013203976A1/en
Publication of AU2010324739B2 publication Critical patent/AU2010324739B2/en
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Assigned to LUNDBECK SEATTLE BIOPHARMACEUTICALS, INC reassignment LUNDBECK SEATTLE BIOPHARMACEUTICALS, INC Request to Amend Deed and Register Assignors: ALDER BIOPHARMACEUTICALS, INC.
Assigned to H. LUNDBECK A/S. reassignment H. LUNDBECK A/S. Request for Assignment Assignors: LUNDBECK SEATTLE BIOPHARMACEUTICALS, INC
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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US12/624,816 US8337847B2 (en) 2008-11-25 2009-11-24 Methods of treating anemia using anti-IL-6 antibodies
US12/624,830 2009-11-24
US12/624,830 US8277804B2 (en) 2008-05-21 2009-11-24 Antagonists of IL-6 to prevent or treat thrombosis
US12/624,965 US8420089B2 (en) 2008-11-25 2009-11-24 Antagonists of IL-6 to raise albumin and/or lower CRP
US12/624,816 2009-11-24
US12/624,778 US9452227B2 (en) 2008-11-25 2009-11-24 Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
US12/624,965 2009-11-24
US12/624,778 2009-11-24
US32554710P 2010-04-19 2010-04-19
US61/325,547 2010-04-19
US35581910P 2010-06-17 2010-06-17
US61/355,819 2010-06-17
US35861510P 2010-06-25 2010-06-25
US61/358,615 2010-06-25
US41016910P 2010-11-04 2010-11-04
US61/410,169 2010-11-04
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