AU2008323514B2 - Novel thermosensitive liposomes containing therapeutic agents - Google Patents

Novel thermosensitive liposomes containing therapeutic agents Download PDF

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Publication number
AU2008323514B2
AU2008323514B2 AU2008323514A AU2008323514A AU2008323514B2 AU 2008323514 B2 AU2008323514 B2 AU 2008323514B2 AU 2008323514 A AU2008323514 A AU 2008323514A AU 2008323514 A AU2008323514 A AU 2008323514A AU 2008323514 B2 AU2008323514 B2 AU 2008323514B2
Authority
AU
Australia
Prior art keywords
liposomes
liposome
thermosensitive
agent
active agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008323514A
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English (en)
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AU2008323514A2 (en
AU2008323514A1 (en
Inventor
Qingwei Jiang
Xingguo Mei
Weiping Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imunon Inc
Original Assignee
Celsion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celsion Corp filed Critical Celsion Corp
Publication of AU2008323514A1 publication Critical patent/AU2008323514A1/en
Assigned to CELSION CORPORATION reassignment CELSION CORPORATION Amend patent request/document other than specification (104) Assignors: JIANG, QINGWEI, MEI, XINGGUO, YU, WEIPING
Assigned to CELSION CORPORATION reassignment CELSION CORPORATION Request for Assignment Assignors: JIANG, QINGWEI, MEI, XINGGUO, YU, WEIPING
Assigned to YU, WEIPING, MEI, XINGGUO, JIANG, QINGWEI reassignment YU, WEIPING Amend patent request/document other than specification (104) Assignors: CELSION CORPORATION
Publication of AU2008323514A2 publication Critical patent/AU2008323514A2/en
Application granted granted Critical
Publication of AU2008323514B2 publication Critical patent/AU2008323514B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2008323514A 2007-11-05 2008-11-05 Novel thermosensitive liposomes containing therapeutic agents Ceased AU2008323514B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/CN2007/003128 WO2009059449A1 (en) 2007-11-05 2007-11-05 Novel thermosensitive liposomes containing therapeutic agents
AUPCT/CN2007/003128 2007-11-05
PCT/CN2008/001846 WO2009062398A1 (en) 2007-11-05 2008-11-05 Novel thermosensitive liposomes containing therapeutic agents

Publications (3)

Publication Number Publication Date
AU2008323514A1 AU2008323514A1 (en) 2009-05-22
AU2008323514A2 AU2008323514A2 (en) 2012-05-17
AU2008323514B2 true AU2008323514B2 (en) 2014-06-12

Family

ID=40625343

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008323514A Ceased AU2008323514B2 (en) 2007-11-05 2008-11-05 Novel thermosensitive liposomes containing therapeutic agents

Country Status (14)

Country Link
US (1) US8642074B2 (enExample)
EP (1) EP2217209B1 (enExample)
JP (1) JP5570994B2 (enExample)
KR (1) KR101652126B1 (enExample)
CN (1) CN101883557B (enExample)
AU (1) AU2008323514B2 (enExample)
BR (1) BRPI0820505A2 (enExample)
CA (1) CA2704258C (enExample)
ES (1) ES2689259T3 (enExample)
MX (1) MX2010004957A (enExample)
MY (1) MY151268A (enExample)
RU (1) RU2497499C2 (enExample)
TW (1) TWI437995B (enExample)
WO (2) WO2009059449A1 (enExample)

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CN102579323B (zh) * 2011-02-21 2013-06-19 舒泰神(北京)生物制药股份有限公司 一种紫杉醇醇质体凝胶剂及其制备方法
CN102688193B (zh) * 2011-03-24 2016-05-11 中国人民解放军军事医学科学院毒物药物研究所 长春碱类药物的热敏脂质体制剂及其制备方法
US10117881B2 (en) 2011-06-03 2018-11-06 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies
US10449193B2 (en) * 2011-06-03 2019-10-22 Signpath Pharma Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies
US12004868B2 (en) 2011-06-03 2024-06-11 Signpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel
CA2836904C (en) 2011-06-03 2019-09-24 Signpath Pharma Inc. Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current
US10532045B2 (en) 2013-12-18 2020-01-14 Signpath Pharma, Inc. Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel
US10349884B2 (en) 2011-06-03 2019-07-16 Sighpath Pharma Inc. Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel
US10238602B2 (en) 2011-06-03 2019-03-26 Signpath Pharma, Inc. Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies
KR20130042905A (ko) * 2011-10-19 2013-04-29 삼성전자주식회사 엘라스틴 유사 폴리펩티드를 포함하는 리포좀 및 그의 용도
CN102552144A (zh) * 2012-01-13 2012-07-11 北京大学 一种靶向热敏脂质体
CN106727329B (zh) * 2012-02-17 2020-11-03 效思因公司 热敏纳米颗粒制剂及其制备方法
ITRM20120169A1 (it) 2012-04-19 2013-10-20 Consiglio Nazionale Ricerche Dispositivo di rilascio di specie chimiche a controllo ottico
WO2013172358A1 (ja) * 2012-05-14 2013-11-21 公立大学法人大阪府立大学 機能性化合物及びその化合物を含有する分子集合体、並びにそれらを含有する組成物及びキット並びにそれらの使用
TR201908531T4 (tr) * 2012-11-20 2019-08-21 Arbutus Biopharma Corp Terapöti̇k kullanim i̇çi̇n li̇pozom kapsüllü vi̇nkri̇sti̇ni̇n preparasyonuna yöneli̇k geli̇şti̇ri̇lmi̇ş yöntem
KR102109188B1 (ko) 2013-04-01 2020-05-11 삼성전자주식회사 양이온성 지질을 포함하는 온도민감성 리포좀 및 그의 용도
TWI552761B (zh) 2013-05-03 2016-10-11 博信生物科技股份有限公司 一種脂質微/奈米氣泡、及其最佳化之製備方法及製備裝置
KR20150034517A (ko) 2013-09-26 2015-04-03 삼성전자주식회사 소수성 활성 성분 및 폴리펩티드의 복합체를 포함하는 리포좀, 및 그의 용도
KR20150047336A (ko) 2013-10-24 2015-05-04 삼성전자주식회사 나노입자, 이를 제조하는 방법, 및 이의 용도
KR20150062652A (ko) 2013-11-29 2015-06-08 삼성전자주식회사 초음파 감응성 리포좀, 그를 포함한 약제학적 조성물 및 그를 이용하여 개체의 체내에 활성제를 전달하는 방법
JP2017516813A (ja) 2014-06-03 2017-06-22 サインパス ファルマ, インク.Signpath Pharma, Inc. チャネル病を引き起こす薬物に対するdmpc、dmpg、dmpc/dmpg、egpg、lysopg及びlysopcの防御効果
US20160346221A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
WO2016196648A1 (en) * 2015-06-01 2016-12-08 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
CN120392779A (zh) * 2015-06-15 2025-08-01 华盛顿大学 用于延长血液和淋巴组织中的药物水平的多药脂质纳米颗粒组合物和相关方法
CN108366965B (zh) 2015-10-16 2021-10-01 易普森生物制药有限公司 稳定喜树碱药物组合物
WO2017078009A1 (ja) 2015-11-02 2017-05-11 富士フイルム株式会社 リポソーム組成物およびその製造方法
ES3014023T3 (en) 2016-04-27 2025-04-16 Signpath Pharma Inc Prevention of drug-induced atrio-ventricular block
BR112021009940A8 (pt) * 2018-11-02 2023-03-21 Tesorx Pharma Llc Método e kit de tratamento de um neoplasma
CN110292563B (zh) * 2019-06-12 2021-07-16 兰州大学 基于叶酸热敏脂质体的阴离子载体诱导癌细胞凋亡的方法
US12023055B2 (en) 2020-08-24 2024-07-02 National Tsing Hua University Balloon catheter system assisted by ultrasound and microbubbles and method for vasodilation
WO2023186923A1 (en) 2022-03-30 2023-10-05 Meta Materials Inc. Implanted agent delivery system
CN114832117A (zh) * 2022-05-20 2022-08-02 天津科技大学 一种细胞穿透肽修饰的核酸-阳离子热敏脂质体及其制备方法
EP4670711A1 (en) * 2023-02-24 2025-12-31 Rossi Bergmann, Bartira LIPOSOME, METHOD FOR PREPARING A LIPOSOME, INTRANASAL COMPOSITION COMPRISING A LIPOSOME, METHOD FOR PREPARING AN INTRANASAL COMPOSITION, KIT AND USE OF THE COMPOSITION

Citations (1)

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US6726925B1 (en) * 1998-06-18 2004-04-27 Duke University Temperature-sensitive liposomal formulation

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Also Published As

Publication number Publication date
US20110200665A1 (en) 2011-08-18
JP2011502134A (ja) 2011-01-20
ES2689259T3 (es) 2018-11-12
EP2217209A4 (en) 2013-09-25
US8642074B2 (en) 2014-02-04
RU2010123009A (ru) 2011-12-20
RU2497499C2 (ru) 2013-11-10
BRPI0820505A2 (pt) 2015-06-16
JP5570994B2 (ja) 2014-08-13
TW200930380A (en) 2009-07-16
WO2009062398A1 (en) 2009-05-22
MX2010004957A (es) 2010-08-02
CN101883557A (zh) 2010-11-10
CN101883557B (zh) 2013-05-29
HK1146906A1 (en) 2011-07-22
AU2008323514A2 (en) 2012-05-17
EP2217209B1 (en) 2018-06-06
WO2009059449A1 (en) 2009-05-14
EP2217209A1 (en) 2010-08-18
TWI437995B (zh) 2014-05-21
MY151268A (en) 2014-04-30
KR101652126B1 (ko) 2016-08-29
KR20100087030A (ko) 2010-08-02
CA2704258A1 (en) 2009-05-22
AU2008323514A1 (en) 2009-05-22
CA2704258C (en) 2016-11-22

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: CELSION CORPORATION

Free format text: FORMER APPLICANT(S): YU, WEIPING; MEI, XINGGUO; JIANG, QINGWEI

TH Corrigenda

Free format text: IN VOL 24, NO 32, PAGE(S) 3679 UNDER THE HEADING CHANGE OF NAMES(S) OF APPLICANT(S), SECTION 104 - 2008 UNDER APPLICATION NO. 2008323514, DELETE ALL REFERENCE TO THIS PUBLICATION ACTION

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 14 MAY 2010

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired