JP5570994B2 - 治療薬を含有する新規な温度感受性リポソーム - Google Patents
治療薬を含有する新規な温度感受性リポソーム Download PDFInfo
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- JP5570994B2 JP5570994B2 JP2010531403A JP2010531403A JP5570994B2 JP 5570994 B2 JP5570994 B2 JP 5570994B2 JP 2010531403 A JP2010531403 A JP 2010531403A JP 2010531403 A JP2010531403 A JP 2010531403A JP 5570994 B2 JP5570994 B2 JP 5570994B2
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- liposomes
- liposome
- item
- carboplatin
- temperature
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
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- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| CNPCT/CN2007/003128 | 2007-11-05 | ||
| PCT/CN2007/003128 WO2009059449A1 (en) | 2007-11-05 | 2007-11-05 | Novel thermosensitive liposomes containing therapeutic agents |
| PCT/CN2008/001846 WO2009062398A1 (en) | 2007-11-05 | 2008-11-05 | Novel thermosensitive liposomes containing therapeutic agents |
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| JP2011502134A JP2011502134A (ja) | 2011-01-20 |
| JP2011502134A5 JP2011502134A5 (enExample) | 2011-12-22 |
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| AU (1) | AU2008323514B2 (enExample) |
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| CN102579323B (zh) * | 2011-02-21 | 2013-06-19 | 舒泰神（北京）生物制药股份有限公司 | 一种紫杉醇醇质体凝胶剂及其制备方法 |
| CN102688193B (zh) * | 2011-03-24 | 2016-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 长春碱类药物的热敏脂质体制剂及其制备方法 |
| US10349884B2 (en) | 2011-06-03 | 2019-07-16 | Sighpath Pharma Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac ikr channel |
| US10117881B2 (en) | 2011-06-03 | 2018-11-06 | Signpath Pharma, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, LYSOPG and LYSOPC against drugs that cause channelopathies |
| US10238602B2 (en) | 2011-06-03 | 2019-03-26 | Signpath Pharma, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies |
| US12004868B2 (en) | 2011-06-03 | 2024-06-11 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel |
| US10449193B2 (en) * | 2011-06-03 | 2019-10-22 | Signpath Pharma Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies |
| EP2714011B1 (en) | 2011-06-03 | 2018-01-31 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current |
| KR20130042905A (ko) * | 2011-10-19 | 2013-04-29 | 삼성전자주식회사 | 엘라스틴 유사 폴리펩티드를 포함하는 리포좀 및 그의 용도 |
| CN102552144A (zh) * | 2012-01-13 | 2012-07-11 | 北京大学 | 一种靶向热敏脂质体 |
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| TWI552761B (zh) * | 2013-05-03 | 2016-10-11 | 博信生物科技股份有限公司 | 一種脂質微／奈米氣泡、及其最佳化之製備方法及製備裝置 |
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| CN107708672A (zh) * | 2015-06-15 | 2018-02-16 | 华盛顿大学 | 用于延长血液和淋巴组织中的药物水平的多药脂质纳米颗粒组合物和相关方法 |
| BR112018006922B1 (pt) | 2015-10-16 | 2023-11-21 | Ipsen Biopharm Ltd | Composições de irinotecano lipossômico estabilizado para armazenamento |
| EP3372223B1 (en) * | 2015-11-02 | 2024-04-17 | FUJIFILM Corporation | Liposome composition and method for producing same |
| ES3014023T3 (en) | 2016-04-27 | 2025-04-16 | Signpath Pharma Inc | Prevention of drug-induced atrio-ventricular block |
| SG11202104580PA (en) * | 2018-11-02 | 2021-05-28 | Tesorx Pharma Llc | Liposomal enhanced intra-peritoneal chemotherapy |
| CN110292563B (zh) * | 2019-06-12 | 2021-07-16 | 兰州大学 | 基于叶酸热敏脂质体的阴离子载体诱导癌细胞凋亡的方法 |
| WO2022042531A1 (zh) | 2020-08-24 | 2022-03-03 | 清华大学 | 超声波搭配微气泡辅助的气球导管系统及其血管扩张方法 |
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| CN114832117A (zh) * | 2022-05-20 | 2022-08-02 | 天津科技大学 | 一种细胞穿透肽修饰的核酸-阳离子热敏脂质体及其制备方法 |
| WO2024174011A1 (pt) * | 2023-02-24 | 2024-08-29 | Rossi Bergmann Bartira | Lipossoma, método de preparo de um lipossoma, composição intranasal compreendendo lipossoma, método de preparo de composição intranasal, kit e uso da composição |
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| US3993754A (en) | 1974-10-09 | 1976-11-23 | The United States Of America As Represented By The United States Energy Research And Development Administration | Liposome-encapsulated actinomycin for cancer chemotherapy |
| US4863739A (en) | 1987-05-19 | 1989-09-05 | Board Of Regents, The University Of Texas System | Liposome compositions of anthracycline derivatives |
| US4952408A (en) | 1988-05-23 | 1990-08-28 | Georgetown University | Liposome-encapsulated vinca alkaloids and their use in combatting tumors |
| JPH05194192A (ja) * | 1991-08-21 | 1993-08-03 | Shionogi & Co Ltd | 分散性の改善された温度感受性ｍｌｖ型リポソ−ム |
| CA2186745A1 (en) | 1994-03-28 | 1995-10-05 | Hiroshi Kikuchi | Liposome with increased retention volume |
| US20050019266A1 (en) * | 1997-05-06 | 2005-01-27 | Unger Evan C. | Novel targeted compositions for diagnostic and therapeutic use |
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| US6200598B1 (en) | 1998-06-18 | 2001-03-13 | Duke University | Temperature-sensitive liposomal formulation |
| US6726925B1 (en) * | 1998-06-18 | 2004-04-27 | Duke University | Temperature-sensitive liposomal formulation |
| EP1448165B1 (en) | 2001-11-13 | 2007-09-19 | Celator Pharmaceuticals, Inc. | Lipid carrier compositions and methods for improved drug retention |
| WO2005094790A1 (es) | 2004-04-02 | 2005-10-13 | Italfarmaco, S.A. | Formulaciones liposomales |
| TWI388344B (zh) | 2005-08-23 | 2013-03-11 | Celsion Corp | 儲存奈米微粒調合物之方法 |
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Also Published As
| Publication number | Publication date |
|---|---|
| KR20100087030A (ko) | 2010-08-02 |
| HK1146906A1 (en) | 2011-07-22 |
| MX2010004957A (es) | 2010-08-02 |
| WO2009059449A1 (en) | 2009-05-14 |
| US8642074B2 (en) | 2014-02-04 |
| AU2008323514A1 (en) | 2009-05-22 |
| TW200930380A (en) | 2009-07-16 |
| TWI437995B (zh) | 2014-05-21 |
| ES2689259T3 (es) | 2018-11-12 |
| US20110200665A1 (en) | 2011-08-18 |
| EP2217209A1 (en) | 2010-08-18 |
| AU2008323514B2 (en) | 2014-06-12 |
| JP2011502134A (ja) | 2011-01-20 |
| WO2009062398A1 (en) | 2009-05-22 |
| EP2217209B1 (en) | 2018-06-06 |
| EP2217209A4 (en) | 2013-09-25 |
| CA2704258A1 (en) | 2009-05-22 |
| KR101652126B1 (ko) | 2016-08-29 |
| BRPI0820505A2 (pt) | 2015-06-16 |
| CN101883557A (zh) | 2010-11-10 |
| RU2497499C2 (ru) | 2013-11-10 |
| MY151268A (en) | 2014-04-30 |
| CA2704258C (en) | 2016-11-22 |
| AU2008323514A2 (en) | 2012-05-17 |
| RU2010123009A (ru) | 2011-12-20 |
| CN101883557B (zh) | 2013-05-29 |
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