JP5570994B2 - 治療薬を含有する新規な温度感受性リポソーム - Google Patents
治療薬を含有する新規な温度感受性リポソーム Download PDFInfo
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- JP5570994B2 JP5570994B2 JP2010531403A JP2010531403A JP5570994B2 JP 5570994 B2 JP5570994 B2 JP 5570994B2 JP 2010531403 A JP2010531403 A JP 2010531403A JP 2010531403 A JP2010531403 A JP 2010531403A JP 5570994 B2 JP5570994 B2 JP 5570994B2
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- liposomes
- liposome
- item
- carboplatin
- temperature
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
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| PCT/CN2007/003128 WO2009059449A1 (en) | 2007-11-05 | 2007-11-05 | Novel thermosensitive liposomes containing therapeutic agents |
| CNPCT/CN2007/003128 | 2007-11-05 | ||
| PCT/CN2008/001846 WO2009062398A1 (en) | 2007-11-05 | 2008-11-05 | Novel thermosensitive liposomes containing therapeutic agents |
Publications (3)
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| JP2011502134A JP2011502134A (ja) | 2011-01-20 |
| JP2011502134A5 JP2011502134A5 (enExample) | 2011-12-22 |
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| CN102688193B (zh) * | 2011-03-24 | 2016-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 长春碱类药物的热敏脂质体制剂及其制备方法 |
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| US10449193B2 (en) * | 2011-06-03 | 2019-10-22 | Signpath Pharma Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, lysoPG and lysoPC against drugs that cause channelopathies |
| US12004868B2 (en) | 2011-06-03 | 2024-06-11 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel |
| CA2836904C (en) | 2011-06-03 | 2019-09-24 | Signpath Pharma Inc. | Liposomal mitigation of drug-induced long qt syndrome and potassium delayed-rectifier current |
| US10532045B2 (en) | 2013-12-18 | 2020-01-14 | Signpath Pharma, Inc. | Liposomal mitigation of drug-induced inhibition of the cardiac IKr channel |
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| US10238602B2 (en) | 2011-06-03 | 2019-03-26 | Signpath Pharma, Inc. | Protective effect of DMPC, DMPG, DMPC/DMPG, LysoPG and LysoPC against drugs that cause channelopathies |
| KR20130042905A (ko) * | 2011-10-19 | 2013-04-29 | 삼성전자주식회사 | 엘라스틴 유사 폴리펩티드를 포함하는 리포좀 및 그의 용도 |
| CN102552144A (zh) * | 2012-01-13 | 2012-07-11 | 北京大学 | 一种靶向热敏脂质体 |
| CN106727329B (zh) * | 2012-02-17 | 2020-11-03 | 效思因公司 | 热敏纳米颗粒制剂及其制备方法 |
| ITRM20120169A1 (it) | 2012-04-19 | 2013-10-20 | Consiglio Nazionale Ricerche | Dispositivo di rilascio di specie chimiche a controllo ottico |
| WO2013172358A1 (ja) * | 2012-05-14 | 2013-11-21 | 公立大学法人大阪府立大学 | 機能性化合物及びその化合物を含有する分子集合体、並びにそれらを含有する組成物及びキット並びにそれらの使用 |
| TR201908531T4 (tr) * | 2012-11-20 | 2019-08-21 | Arbutus Biopharma Corp | Terapöti̇k kullanim i̇çi̇n li̇pozom kapsüllü vi̇nkri̇sti̇ni̇n preparasyonuna yöneli̇k geli̇şti̇ri̇lmi̇ş yöntem |
| KR102109188B1 (ko) | 2013-04-01 | 2020-05-11 | 삼성전자주식회사 | 양이온성 지질을 포함하는 온도민감성 리포좀 및 그의 용도 |
| TWI552761B (zh) | 2013-05-03 | 2016-10-11 | 博信生物科技股份有限公司 | 一種脂質微／奈米氣泡、及其最佳化之製備方法及製備裝置 |
| KR20150034517A (ko) | 2013-09-26 | 2015-04-03 | 삼성전자주식회사 | 소수성 활성 성분 및 폴리펩티드의 복합체를 포함하는 리포좀, 및 그의 용도 |
| KR20150047336A (ko) | 2013-10-24 | 2015-05-04 | 삼성전자주식회사 | 나노입자, 이를 제조하는 방법, 및 이의 용도 |
| KR20150062652A (ko) | 2013-11-29 | 2015-06-08 | 삼성전자주식회사 | 초음파 감응성 리포좀, 그를 포함한 약제학적 조성물 및 그를 이용하여 개체의 체내에 활성제를 전달하는 방법 |
| JP2017516813A (ja) | 2014-06-03 | 2017-06-22 | サインパス ファルマ, インク.Signpath Pharma, Inc. | チャネル病を引き起こす薬物に対するｄｍｐｃ、ｄｍｐｇ、ｄｍｐｃ／ｄｍｐｇ、ｅｇｐｇ、ｌｙｓｏｐｇ及びｌｙｓｏｐｃの防御効果 |
| US20160346221A1 (en) | 2015-06-01 | 2016-12-01 | Autotelic Llc | Phospholipid-coated therapeutic agent nanoparticles and related methods |
| WO2016196648A1 (en) * | 2015-06-01 | 2016-12-08 | Autotelic Llc | Phospholipid-coated therapeutic agent nanoparticles and related methods |
| CN120392779A (zh) * | 2015-06-15 | 2025-08-01 | 华盛顿大学 | 用于延长血液和淋巴组织中的药物水平的多药脂质纳米颗粒组合物和相关方法 |
| CN108366965B (zh) | 2015-10-16 | 2021-10-01 | 易普森生物制药有限公司 | 稳定喜树碱药物组合物 |
| WO2017078009A1 (ja) | 2015-11-02 | 2017-05-11 | 富士フイルム株式会社 | リポソーム組成物およびその製造方法 |
| ES3014023T3 (en) | 2016-04-27 | 2025-04-16 | Signpath Pharma Inc | Prevention of drug-induced atrio-ventricular block |
| BR112021009940A8 (pt) * | 2018-11-02 | 2023-03-21 | Tesorx Pharma Llc | Método e kit de tratamento de um neoplasma |
| CN110292563B (zh) * | 2019-06-12 | 2021-07-16 | 兰州大学 | 基于叶酸热敏脂质体的阴离子载体诱导癌细胞凋亡的方法 |
| US12023055B2 (en) | 2020-08-24 | 2024-07-02 | National Tsing Hua University | Balloon catheter system assisted by ultrasound and microbubbles and method for vasodilation |
| WO2023186923A1 (en) | 2022-03-30 | 2023-10-05 | Meta Materials Inc. | Implanted agent delivery system |
| CN114832117A (zh) * | 2022-05-20 | 2022-08-02 | 天津科技大学 | 一种细胞穿透肽修饰的核酸-阳离子热敏脂质体及其制备方法 |
| EP4670711A1 (en) * | 2023-02-24 | 2025-12-31 | Rossi Bergmann, Bartira | LIPOSOME, METHOD FOR PREPARING A LIPOSOME, INTRANASAL COMPOSITION COMPRISING A LIPOSOME, METHOD FOR PREPARING AN INTRANASAL COMPOSITION, KIT AND USE OF THE COMPOSITION |
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| US3993754A (en) | 1974-10-09 | 1976-11-23 | The United States Of America As Represented By The United States Energy Research And Development Administration | Liposome-encapsulated actinomycin for cancer chemotherapy |
| US4863739A (en) | 1987-05-19 | 1989-09-05 | Board Of Regents, The University Of Texas System | Liposome compositions of anthracycline derivatives |
| US4952408A (en) | 1988-05-23 | 1990-08-28 | Georgetown University | Liposome-encapsulated vinca alkaloids and their use in combatting tumors |
| JPH05194192A (ja) | 1991-08-21 | 1993-08-03 | Shionogi & Co Ltd | 分散性の改善された温度感受性ｍｌｖ型リポソ−ム |
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| TWI388344B (zh) * | 2005-08-23 | 2013-03-11 | Celsion Corp | 儲存奈米微粒調合物之方法 |
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| US20110200665A1 (en) | 2011-08-18 |
| JP2011502134A (ja) | 2011-01-20 |
| ES2689259T3 (es) | 2018-11-12 |
| EP2217209A4 (en) | 2013-09-25 |
| US8642074B2 (en) | 2014-02-04 |
| RU2010123009A (ru) | 2011-12-20 |
| RU2497499C2 (ru) | 2013-11-10 |
| BRPI0820505A2 (pt) | 2015-06-16 |
| AU2008323514B2 (en) | 2014-06-12 |
| TW200930380A (en) | 2009-07-16 |
| WO2009062398A1 (en) | 2009-05-22 |
| MX2010004957A (es) | 2010-08-02 |
| CN101883557A (zh) | 2010-11-10 |
| CN101883557B (zh) | 2013-05-29 |
| HK1146906A1 (en) | 2011-07-22 |
| AU2008323514A2 (en) | 2012-05-17 |
| EP2217209B1 (en) | 2018-06-06 |
| WO2009059449A1 (en) | 2009-05-14 |
| EP2217209A1 (en) | 2010-08-18 |
| TWI437995B (zh) | 2014-05-21 |
| MY151268A (en) | 2014-04-30 |
| KR101652126B1 (ko) | 2016-08-29 |
| KR20100087030A (ko) | 2010-08-02 |
| CA2704258A1 (en) | 2009-05-22 |
| AU2008323514A1 (en) | 2009-05-22 |
| CA2704258C (en) | 2016-11-22 |
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