AU2006291054B2 - Recurrent gene fusions in prostate cancer - Google Patents

Recurrent gene fusions in prostate cancer Download PDF

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Publication number
AU2006291054B2
AU2006291054B2 AU2006291054A AU2006291054A AU2006291054B2 AU 2006291054 B2 AU2006291054 B2 AU 2006291054B2 AU 2006291054 A AU2006291054 A AU 2006291054A AU 2006291054 A AU2006291054 A AU 2006291054A AU 2006291054 B2 AU2006291054 B2 AU 2006291054B2
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gene
erg
fusion
tmprss2
family member
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AU2006291054A1 (en
Inventor
Arul Chinnaiyan
Francesca Demichelis
Charles Lee
Rohit Mehra
Sven Perner
Daniel Rhodes
Mark A. Rubin
Xiao-Wei Sun
Scott Tomlins
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Brigham and Womens Hospital Inc
University of Michigan System
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Brigham and Womens Hospital Inc
University of Michigan System
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    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • A—HUMAN NECESSITIES
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    • A01K2227/105—Murine
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
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    • A01K2267/0331—Animal model for proliferative diseases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
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    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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AU2006291054A 2005-09-12 2006-09-12 Recurrent gene fusions in prostate cancer Active AU2006291054B2 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US71643605P 2005-09-12 2005-09-12
US60/716,436 2005-09-12
US73035805P 2005-10-27 2005-10-27
US60/730,358 2005-10-27
US77904106P 2006-03-03 2006-03-03
US60/779,041 2006-03-03
US79559006P 2006-04-28 2006-04-28
US60/795,590 2006-04-28
PCT/US2006/035507 WO2007033187A2 (en) 2005-09-12 2006-09-12 Recurrent gene fusions in prostate cancer

Publications (2)

Publication Number Publication Date
AU2006291054A1 AU2006291054A1 (en) 2007-03-22
AU2006291054B2 true AU2006291054B2 (en) 2011-10-13

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ID=37865521

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AU2006291054A Active AU2006291054B2 (en) 2005-09-12 2006-09-12 Recurrent gene fusions in prostate cancer

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US (9) US7718369B2 (OSRAM)
EP (2) EP2612870A1 (OSRAM)
JP (1) JP5512125B2 (OSRAM)
AU (1) AU2006291054B2 (OSRAM)
CA (2) CA2814598A1 (OSRAM)
DE (1) DE06814528T1 (OSRAM)
IL (1) IL190095A (OSRAM)
WO (1) WO2007033187A2 (OSRAM)

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