AU2006218012A1 - Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neurotransmission - Google Patents

Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neurotransmission Download PDF

Info

Publication number
AU2006218012A1
AU2006218012A1 AU2006218012A AU2006218012A AU2006218012A1 AU 2006218012 A1 AU2006218012 A1 AU 2006218012A1 AU 2006218012 A AU2006218012 A AU 2006218012A AU 2006218012 A AU2006218012 A AU 2006218012A AU 2006218012 A1 AU2006218012 A1 AU 2006218012A1
Authority
AU
Australia
Prior art keywords
disorders
phenyl
compound
disorder
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006218012A
Other languages
English (en)
Inventor
Jean-Louise Burgot
Marylene Chollet
Marie-Odile Christen
Benjamin Drukarch
Roelof W. Feenstra
Wouter I. Iwema Bakker
Anton N. M. Schoffelmeer
Martinus Tulp
Bernard J. Van Vliet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Healthcare Products BV
Original Assignee
Solvay Pharmaceuticals BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals BV filed Critical Solvay Pharmaceuticals BV
Publication of AU2006218012A1 publication Critical patent/AU2006218012A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/04Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Anesthesiology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2006218012A 2005-02-24 2006-02-17 Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neurotransmission Abandoned AU2006218012A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US65542805P 2005-02-24 2005-02-24
EP05101405.8 2005-02-24
US60/655,428 2005-02-24
EP05101405 2005-02-24
PCT/EP2006/060060 WO2006089861A2 (en) 2005-02-24 2006-02-17 Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neurotransmission

Publications (1)

Publication Number Publication Date
AU2006218012A1 true AU2006218012A1 (en) 2006-08-31

Family

ID=34938805

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006218012A Abandoned AU2006218012A1 (en) 2005-02-24 2006-02-17 Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neurotransmission

Country Status (14)

Country Link
EP (1) EP1858875A2 (zh)
JP (1) JP2008531519A (zh)
KR (1) KR20070117607A (zh)
CN (1) CN101107240B (zh)
AR (1) AR055862A1 (zh)
AU (1) AU2006218012A1 (zh)
BR (1) BRPI0609043A2 (zh)
CA (1) CA2594165A1 (zh)
MX (1) MX2007010380A (zh)
RU (1) RU2402543C2 (zh)
SA (1) SA06270023B1 (zh)
TW (1) TW200640898A (zh)
UA (1) UA94579C2 (zh)
WO (1) WO2006089861A2 (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0704718D0 (en) * 2007-03-12 2007-04-18 Prendergast Patrick T Compounds and methods for preventing and treating mucositis
CN102807557B (zh) * 2012-08-21 2015-02-04 苏州大学 3h-1,2-二硫环戊烯-3-硫酮类化合物及其应用
KR101438415B1 (ko) * 2013-07-25 2014-09-17 동국대학교 경주캠퍼스 산학협력단 기억력 손상의 예방 또는 개선을 위한 조구등 추출물
CN104788440B (zh) * 2015-04-03 2017-12-26 苏州大学 烟酸衍生物及其应用
FR3063640B1 (fr) * 2017-03-07 2020-10-09 Elodie Petitjean Traitement de la fibrose pulmonaire a l'aide d'un inhibiteur selectif de la production d'especes reactives de l'oxygene d'origine mitochondriale
EP3592348A1 (en) 2017-03-07 2020-01-15 Op2 Drugs Desmethylanethole trithione derivatives for the treatment of diseases linked to mitochondrial reactive oxygen species (ros) production
AU2019341666A1 (en) * 2018-09-18 2021-05-13 St Ip Holding Ag Rotomeric isomers of 4-alkyl-5-heteroaryl-3H-1,2- dithiole-3-thiones

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1442450A (fr) * 1964-05-05 1966-06-17 Monsanto Chemicals Nouveaux composés hétérocycliques contenant du soufre
JPH089611B2 (ja) * 1988-06-20 1996-01-31 三井東圧化学株式会社 新規1,2−ジチオール−3−チオン誘導体およびそれを有効成分とする免疫調節剤
WO1998027970A2 (en) * 1996-12-24 1998-07-02 National Research Council Of Canada Treatment of diseases or prevention of cellular damage caused by oxygen-containing free radicals
WO2001009118A2 (en) * 1999-07-29 2001-02-08 Patrick T Prendergast Dithiolthione compounds for the treatment of neurological disorders and for memory enhancement

Also Published As

Publication number Publication date
MX2007010380A (es) 2007-09-25
UA94579C2 (ru) 2011-05-25
CA2594165A1 (en) 2006-08-31
WO2006089861A3 (en) 2006-10-26
KR20070117607A (ko) 2007-12-12
RU2007135184A (ru) 2009-03-27
CN101107240A (zh) 2008-01-16
CN101107240B (zh) 2011-02-09
RU2402543C2 (ru) 2010-10-27
AR055862A1 (es) 2007-09-12
SA06270023A (ar) 2005-12-03
TW200640898A (en) 2006-12-01
JP2008531519A (ja) 2008-08-14
EP1858875A2 (en) 2007-11-28
BRPI0609043A2 (pt) 2010-11-16
SA06270023B1 (ar) 2010-10-12
WO2006089861A2 (en) 2006-08-31

Similar Documents

Publication Publication Date Title
RU2348620C2 (ru) Производные тиазола в качестве модуляторов каннабиноидного рецептора
ES2270873T3 (es) Derivados de heterociclos de 5 miembros y su aplicacion como inhibidores de monoamina oxidasa.
AU2006218012A1 (en) Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neurotransmission
RU2323219C2 (ru) Производные тиоксантина в качестве ингибиторов миелопероксидазы
US20060004041A1 (en) Compounds for treatment of neurodegenerative diseases
US5326770A (en) Monoamine oxidase-B (MAO-B) inhibitory 5-substituted 2,4-thiazolidinediones useful in treating memory disorders of mammals
HRP960349A2 (en) Therapeutic agents
JP2008543726A (ja) 炎症性疾患の処置のためのpgd2受容体アンタゴニスト
PL205507B1 (pl) Pochodna β-karboliny i jej zastosowanie oraz kompozycja farmaceutyczna
JP2007529468A (ja) ベンズイソオキサゾール
CN102652135A (zh) 脂肪酸酰胺水解酶的含氮杂环抑制剂
EP2091939B1 (en) Compounds with a combination of cannabinoid-cb1 antagonism and acetylcholinesterase inhibition
CN108623537B (zh) 含胺基侧链的芳香胺类乙酰胆碱酯酶抑制剂合成与用途
KR100248643B1 (ko) 아릴 및 헤테로아릴 알콕시나프탈렌 유도체
SK138993A3 (en) Amidoalkyl - and imidoalkylpiperazines
US20060194971A1 (en) Anethole dithiolethione and other dithiolethiones for the treatment of conditions associated with dysfunction of monoamine neruotransmission
AU2005313386A1 (en) Phenylpiperazines with a combination of affinity for dopamine -D2 receptors and serotonin reuptake sites
PL197847B1 (pl) Pochodne indoli oraz ich zastosowanie do wytwarzania leków
SG185411A1 (en) Modulators of fatty acid amide hydrolase
CA2251814A1 (en) N-aminoalkyl-2-anthraquinonecarboxamides; new dopamine receptor subtype specific ligands
CN114478359B (zh) 氨基甲酸酯类trpv1拮抗/faah抑制双靶点药物及其制备方法和应用
SK8652003A3 (en) Piperazinylcarbonylquinoline and piperazinylcarbonylisoquinoline derivative, process for the preparation thereof, use and pharmaceutical composition comprising same
SK6942002A3 (en) Sulfonyl oxazole amine derivative, process for the preparation thereof, its use and pharmaceutical composition containing same
JPH0459754A (ja) アミド誘導体
WO2008132162A1 (en) 3- (sulphonylamino) -phenyl-2 -hydroxy-ethylamino derivatives useful as beta-agonists, processes for preparing them and their use as medicaments

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application