AU2005304784B2 - Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases - Google Patents

Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases Download PDF

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Publication number
AU2005304784B2
AU2005304784B2 AU2005304784A AU2005304784A AU2005304784B2 AU 2005304784 B2 AU2005304784 B2 AU 2005304784B2 AU 2005304784 A AU2005304784 A AU 2005304784A AU 2005304784 A AU2005304784 A AU 2005304784A AU 2005304784 B2 AU2005304784 B2 AU 2005304784B2
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compound
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cornpound
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pct
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AU2005304784A1 (en
Inventor
Alex Aronov
Jean-Damien Charrier
Jon R. Come
Juan-Miguel Jimenez
Ronald Knegtel
Pan Li
Dean Stamos
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • AIDS & HIV (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
AU2005304784A 2004-11-04 2005-11-04 Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases Ceased AU2005304784B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62544604P 2004-11-04 2004-11-04
US60/625,446 2004-11-04
PCT/US2005/040344 WO2006052913A1 (en) 2004-11-04 2005-11-04 PYRAZOLO[1,5-a]PYRIMIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES

Publications (2)

Publication Number Publication Date
AU2005304784A1 AU2005304784A1 (en) 2006-05-18
AU2005304784B2 true AU2005304784B2 (en) 2011-03-24

Family

ID=35809833

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Application Number Title Priority Date Filing Date
AU2005304784A Ceased AU2005304784B2 (en) 2004-11-04 2005-11-04 Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases

Country Status (20)

Country Link
US (1) US7528138B2 (enExample)
EP (1) EP1812440B1 (enExample)
JP (2) JP5030229B2 (enExample)
KR (1) KR20070090172A (enExample)
CN (1) CN101094853B (enExample)
AT (1) ATE482213T1 (enExample)
AU (1) AU2005304784B2 (enExample)
CA (1) CA2586375A1 (enExample)
DE (1) DE602005023763D1 (enExample)
DK (1) DK1812440T3 (enExample)
ES (1) ES2354824T3 (enExample)
IL (1) IL182893A0 (enExample)
MX (1) MX337817B (enExample)
NO (1) NO20072795L (enExample)
NZ (1) NZ555236A (enExample)
PT (1) PT1812440E (enExample)
RU (1) RU2417996C2 (enExample)
SI (1) SI1812440T1 (enExample)
WO (1) WO2006052913A1 (enExample)
ZA (1) ZA200704476B (enExample)

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