AU2004299456B2 - (3,4-disubstituted)propanoic carboxylates as S1P (Edg) receptor agonists - Google Patents

(3,4-disubstituted)propanoic carboxylates as S1P (Edg) receptor agonists Download PDF

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Publication number
AU2004299456B2
AU2004299456B2 AU2004299456A AU2004299456A AU2004299456B2 AU 2004299456 B2 AU2004299456 B2 AU 2004299456B2 AU 2004299456 A AU2004299456 A AU 2004299456A AU 2004299456 A AU2004299456 A AU 2004299456A AU 2004299456 B2 AU2004299456 B2 AU 2004299456B2
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group
independently selected
atoms
optionally substituted
mmol
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AU2004299456A1 (en
Inventor
Vincent J. Colandrea
George A. Doherty
Jeffrey J. Hale
Pei Huo
Irene E. Legiec
Leslie Toth
Petr Vachal
Lin Yan
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Merck Sharp and Dohme LLC
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Merck Sharp and Dohme Ltd
Merck Sharp and Dohme LLC
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    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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  • Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
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  • Transplantation (AREA)
AU2004299456A 2003-12-17 2004-12-13 (3,4-disubstituted)propanoic carboxylates as S1P (Edg) receptor agonists Ceased AU2004299456B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53018603P 2003-12-17 2003-12-17
US60/530,186 2003-12-17
PCT/US2004/041887 WO2005058848A1 (en) 2003-12-17 2004-12-13 (3,4-disubstituted)propanoic carboxylates as s1p (edg) receptor agonists

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Publication Number Publication Date
AU2004299456A1 AU2004299456A1 (en) 2005-06-30
AU2004299456B2 true AU2004299456B2 (en) 2010-10-07

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AU2004299456A Ceased AU2004299456B2 (en) 2003-12-17 2004-12-13 (3,4-disubstituted)propanoic carboxylates as S1P (Edg) receptor agonists

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US (1) US7605171B2 (enExample)
EP (1) EP1697333A4 (enExample)
JP (1) JP4773972B2 (enExample)
CN (1) CN1894225A (enExample)
AU (1) AU2004299456B2 (enExample)
CA (1) CA2547198A1 (enExample)
WO (1) WO2005058848A1 (enExample)

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RU2376285C2 (ru) 2004-10-12 2009-12-20 Киорин Фармасьютикал Ко., Лтд. Процесс получения гидрохлорида 2-амино-2-[2-[4-(3-бензилоксифенилтио)-2-хлорфенилэтил]-1,3-пропандиола] и его гидратов, а также промежуточные продукты их получения
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WO2006114400A1 (en) 2005-04-26 2006-11-02 Neurosearch A/S Novel oxadiazole derivatives and their medical use
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CN101501049B (zh) 2006-08-08 2013-04-24 杏林制药株式会社 氨基磷酸酯衍生物以及将它们作为有效成分的s1p受体调节剂
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