AU2004274212B2 - Dimethoxy docetaxel acetone solvate et method for the preparation thereof - Google Patents

Dimethoxy docetaxel acetone solvate et method for the preparation thereof Download PDF

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Publication number
AU2004274212B2
AU2004274212B2 AU2004274212A AU2004274212A AU2004274212B2 AU 2004274212 B2 AU2004274212 B2 AU 2004274212B2 AU 2004274212 A AU2004274212 A AU 2004274212A AU 2004274212 A AU2004274212 A AU 2004274212A AU 2004274212 B2 AU2004274212 B2 AU 2004274212B2
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Australia
Prior art keywords
hydroxy
acetone
set forth
dimethoxy
oxotax
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AU2004274212A
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AU2004274212A1 (en
Inventor
Eric Didier
Marc-Antoine Perrin
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Aventis Pharma SA
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Aventis Pharma SA
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
AU2004274212A 2003-09-19 2004-09-16 Dimethoxy docetaxel acetone solvate et method for the preparation thereof Active 2026-12-08 AU2004274212B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0311016 2003-09-19
FR0311016A FR2859996B1 (fr) 2003-09-19 2003-09-19 Solvat acetonique du dimethoxy docetaxel et son procede de preparation
PCT/FR2004/002344 WO2005028462A1 (fr) 2003-09-19 2004-09-16 Solvat acetonique du dimethoxy docetaxel et son procede de preparation

Publications (2)

Publication Number Publication Date
AU2004274212A1 AU2004274212A1 (en) 2005-03-31
AU2004274212B2 true AU2004274212B2 (en) 2010-03-04

Family

ID=34224354

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004274212A Active 2026-12-08 AU2004274212B2 (en) 2003-09-19 2004-09-16 Dimethoxy docetaxel acetone solvate et method for the preparation thereof

Country Status (37)

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US (1) US7241907B2 (cg-RX-API-DMAC10.html)
EP (1) EP1667986B1 (cg-RX-API-DMAC10.html)
JP (1) JP5010279B2 (cg-RX-API-DMAC10.html)
KR (1) KR101123588B1 (cg-RX-API-DMAC10.html)
CN (1) CN100429207C (cg-RX-API-DMAC10.html)
AR (1) AR045667A1 (cg-RX-API-DMAC10.html)
AU (1) AU2004274212B2 (cg-RX-API-DMAC10.html)
BE (1) BE2013C036I2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0414492A8 (cg-RX-API-DMAC10.html)
CA (1) CA2539309A1 (cg-RX-API-DMAC10.html)
CR (1) CR8292A (cg-RX-API-DMAC10.html)
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DK (1) DK1667986T3 (cg-RX-API-DMAC10.html)
ES (1) ES2403149T4 (cg-RX-API-DMAC10.html)
FR (2) FR2859996B1 (cg-RX-API-DMAC10.html)
HR (1) HRP20130322T1 (cg-RX-API-DMAC10.html)
HU (1) HUS1300025I1 (cg-RX-API-DMAC10.html)
IL (1) IL174240A (cg-RX-API-DMAC10.html)
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RS (2) RS54614B1 (cg-RX-API-DMAC10.html)
RU (1) RU2342373C2 (cg-RX-API-DMAC10.html)
SI (1) SI1667986T1 (cg-RX-API-DMAC10.html)
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UA (1) UA87115C2 (cg-RX-API-DMAC10.html)
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JP2010516625A (ja) 2007-01-24 2010-05-20 インサート セラピューティクス, インコーポレイテッド 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
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CN102675257B (zh) * 2012-05-10 2014-07-02 上海金和生物技术有限公司 一种卡巴他赛晶体及其制备方法
CN102746258B (zh) 2012-07-25 2015-02-04 重庆泰濠制药有限公司 卡巴他赛的结晶形式及其制备方法
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TWI599373B (zh) 2012-08-15 2017-09-21 永信藥品工業股份有限公司 卡巴利他索(cabazitaxel)之穩定醫藥調配物
CN103664836B (zh) * 2012-09-20 2016-04-20 齐鲁制药有限公司 7β,10β-二甲氧基多西紫杉醇氘代丙酮合物的晶型A及其制备方法
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CN103804323A (zh) * 2012-11-14 2014-05-21 上海希迈医药科技有限公司 一种卡巴他赛溶剂化物及其制备方法和应用
CN103058960B (zh) * 2012-12-12 2014-12-10 江苏奥赛康药业股份有限公司 卡巴他赛多晶型形式及其制备方法
EP2743264A1 (en) 2012-12-13 2014-06-18 INDENA S.p.A. New crystalline form of cabazitaxel, process for the preparation and pharmaceutical compositions thereof
CN103910698B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛丙酮合物及其结晶
CN103910696B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛异丙醚合物及其结晶
EP2777691A1 (en) 2013-03-14 2014-09-17 Pharmachemie B.V. Taxoid - Purification of Liquid Excipients
EP2815749A1 (en) 2013-06-20 2014-12-24 IP Gesellschaft für Management mbH Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern
CN104277014A (zh) * 2013-07-04 2015-01-14 北京新天宇科技开发有限公司 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法
WO2015000165A1 (zh) * 2013-07-04 2015-01-08 北京新天宇科技开发有限公司 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法
EP2865675A1 (en) * 2013-10-23 2015-04-29 INDENA S.p.A. A crystalline anhydrous form of Cabazitaxel, process for the preparation and pharmaceutical compositions thereof
EP2865674A1 (en) 2013-10-23 2015-04-29 INDENA S.p.A. Crystalline solvate forms of Cabazitaxel
CN103601704B (zh) * 2013-11-22 2015-05-06 石家庄智恒医药科技有限公司 无定形卡巴他赛的制备
US20180311203A1 (en) 2015-01-12 2018-11-01 Emcure Pharmaceuticals Limited Liquid formulation of cabazitaxel
ES2817331T3 (es) 2015-02-17 2021-04-07 Univ Erasmus Med Ct Rotterdam Uso del cabazitaxel en el tratamiento del cáncer de próstata
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WO1997032869A1 (fr) * 1996-03-06 1997-09-12 Rhone-Poulenc Rorer S.A. Taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
EP0982027A1 (en) * 1998-08-17 2000-03-01 Aventis Pharma S.A. Taxoid derivatives for treating abnormal cell proliferation of the brain

Also Published As

Publication number Publication date
DK1667986T3 (da) 2013-05-06
LU92172I9 (cg-RX-API-DMAC10.html) 2019-01-03
UA87115C2 (ru) 2009-06-25
RU2006113122A (ru) 2006-08-27
KR101123588B1 (ko) 2012-03-22
CN1849311A (zh) 2006-10-18
NZ545835A (en) 2009-10-30
CR8292A (es) 2008-10-15
CY2013016I2 (el) 2018-01-10
CA2539309A1 (fr) 2005-03-31
HK1093340A1 (zh) 2007-03-02
EP1667986A1 (fr) 2006-06-14
MA28045A1 (fr) 2006-07-03
BRPI0414492A8 (pt) 2019-01-15
IL174240A (en) 2010-12-30
ME00054B (me) 2011-02-10
NO20061714L (no) 2006-04-19
PE20050870A1 (es) 2005-11-21
NO335997B1 (no) 2015-04-20
KR20060072147A (ko) 2006-06-27
FR13C0037I1 (fr) 2013-09-08
ES2403149T3 (es) 2013-05-14
RS54614B1 (sr) 2016-08-31
MXPA06002639A (es) 2006-06-05
ES2403149T4 (es) 2013-06-24
US20050065138A1 (en) 2005-03-24
NO2015013I2 (no) 2015-04-22
BE2013C036I2 (cg-RX-API-DMAC10.html) 2023-12-14
PL1667986T3 (pl) 2013-06-28
NO2015013I1 (no) 2015-05-04
PA8612401A1 (es) 2005-08-04
JP5010279B2 (ja) 2012-08-29
IL174240A0 (en) 2006-08-01
AR045667A1 (es) 2005-11-02
CY2013016I1 (el) 2018-01-10
AU2004274212A1 (en) 2005-03-31
MY136668A (en) 2008-11-28
FR2859996A1 (fr) 2005-03-25
ZA200602255B (en) 2007-07-25
FR2859996B1 (fr) 2006-02-03
BRPI0414492A (pt) 2006-11-14
RU2342373C2 (ru) 2008-12-27
SI1667986T1 (sl) 2013-05-31
WO2005028462A1 (fr) 2005-03-31
HRP20130322T1 (en) 2013-07-31
TNSN06086A1 (en) 2007-10-03
HUS1300025I1 (hu) 2016-08-29
RS20060189A (sr) 2008-06-05
TW200524891A (en) 2005-08-01
FR13C0037I2 (fr) 2015-11-20
EP1667986B1 (fr) 2013-01-16
CY1114575T1 (el) 2016-10-05
TWI382022B (zh) 2013-01-11
LU92172I2 (fr) 2013-05-21
CN100429207C (zh) 2008-10-29
US7241907B2 (en) 2007-07-10
PT1667986E (pt) 2013-04-24
MEP11708A (en) 2010-06-10
JP2007505866A (ja) 2007-03-15

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