|
JP2005507881A
(ja)
|
2001-09-17 |
2005-03-24 |
グラクソ グループ リミテッド |
乾燥粉末医薬製剤
|
|
PE20040950A1
(es)
|
2003-02-14 |
2005-01-01 |
Theravance Inc |
DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
|
|
GB0312832D0
(en)
*
|
2003-06-04 |
2003-07-09 |
Pfizer Ltd |
2-amino-pyridine derivatives useful for the treatment of diseases
|
|
GB0316290D0
(en)
|
2003-07-11 |
2003-08-13 |
Glaxo Group Ltd |
Novel compounds
|
|
TW200526547A
(en)
|
2003-09-22 |
2005-08-16 |
Theravance Inc |
Amino-substituted ethylamino β2 adrenergic receptor agonists
|
|
TW200531692A
(en)
|
2004-01-12 |
2005-10-01 |
Theravance Inc |
Aryl aniline derivatives as β2 adrenergic receptor agonists
|
|
GB0401334D0
(en)
|
2004-01-21 |
2004-02-25 |
Novartis Ag |
Organic compounds
|
|
GB0411056D0
(en)
|
2004-05-18 |
2004-06-23 |
Novartis Ag |
Organic compounds
|
|
AR049384A1
(es)
|
2004-05-24 |
2006-07-26 |
Glaxo Group Ltd |
Derivados de purina
|
|
JP2008501705A
(ja)
|
2004-06-03 |
2008-01-24 |
セラヴァンス, インコーポレーテッド |
ジアミンβ2アドレナリン作用性レセプターアゴニスト
|
|
JP2008507532A
(ja)
|
2004-07-21 |
2008-03-13 |
セラヴァンス, インコーポレーテッド |
ジアリールエーテルβ2アドレナリン作用性レセプターアゴニスト
|
|
GB0418045D0
(en)
|
2004-08-12 |
2004-09-15 |
Glaxo Group Ltd |
Compounds
|
|
EP1786762A2
(en)
|
2004-09-10 |
2007-05-23 |
Theravance, Inc. |
Amidine substituted aryl aniline compounds
|
|
GT200500281A
(es)
|
2004-10-22 |
2006-04-24 |
Novartis Ag |
Compuestos organicos.
|
|
GB0424284D0
(en)
|
2004-11-02 |
2004-12-01 |
Novartis Ag |
Organic compounds
|
|
GB0426164D0
(en)
|
2004-11-29 |
2004-12-29 |
Novartis Ag |
Organic compounds
|
|
WO2006072599A2
(en)
|
2005-01-10 |
2006-07-13 |
Glaxo Group Limited |
Androstane 17-alpha carbonate derivatives for use in the treatment of allergic and inflammatory conditions
|
|
PE20061351A1
(es)
|
2005-03-25 |
2007-01-14 |
Glaxo Group Ltd |
COMPUESTOS 8H-PIRIDO[2,3-d]PIRIMIDIN-7-ONA 2,4,8-TRISUSTITUIDOS COMO INHIBIDORES DE LA QUINASA CSBP/RK/p38
|
|
GB0507577D0
(en)
|
2005-04-14 |
2005-05-18 |
Novartis Ag |
Organic compounds
|
|
ES2265276B1
(es)
|
2005-05-20 |
2008-02-01 |
Laboratorios Almirall S.A. |
Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
|
|
TW200726767A
(en)
*
|
2005-07-04 |
2007-07-16 |
Astrazeneca Ab |
Chemical compounds 2
|
|
GB0514809D0
(en)
|
2005-07-19 |
2005-08-24 |
Glaxo Group Ltd |
Compounds
|
|
GB0516313D0
(en)
|
2005-08-08 |
2005-09-14 |
Argenta Discovery Ltd |
Azole derivatives and their uses
|
|
EP1924553A1
(en)
|
2005-08-08 |
2008-05-28 |
Argenta Discovery Limited |
Bicyclo[2.2.]hept-7-ylamine derivatives and their uses
|
|
TW200738658A
(en)
|
2005-08-09 |
2007-10-16 |
Astrazeneca Ab |
Novel compounds
|
|
TW200738659A
(en)
*
|
2005-08-29 |
2007-10-16 |
Astrazeneca Ab |
Novel compounds
|
|
TW200740781A
(en)
*
|
2005-08-29 |
2007-11-01 |
Astrazeneca Ab |
Novel compounds
|
|
EP1957530A2
(en)
|
2005-10-21 |
2008-08-20 |
Novartis AG |
Human antibodies against il13 and therapeutic uses
|
|
PE20071068A1
(es)
|
2005-12-20 |
2007-12-13 |
Glaxo Group Ltd |
Acido 3-(4-{[4-(4-{[3-(3,3-dimetil-1-piperidinil)propil]oxi}fenil)-1-piperidinil]carbonil}-1-naftalenil)propanoico o propenoico, sales de los mismos, como antagonistas de los receptores h1 y h3
|
|
GB0601951D0
(en)
|
2006-01-31 |
2006-03-15 |
Novartis Ag |
Organic compounds
|
|
GB0602778D0
(en)
|
2006-02-10 |
2006-03-22 |
Glaxo Group Ltd |
Novel compound
|
|
TW200745067A
(en)
|
2006-03-14 |
2007-12-16 |
Astrazeneca Ab |
Novel compounds
|
|
AR060536A1
(es)
|
2006-04-20 |
2008-06-25 |
Glaxo Group Ltd |
Agonista del receptor de glucocorticoides y composiciones farmaceuticas
|
|
SI2013211T1
(sl)
|
2006-04-21 |
2012-07-31 |
Novartis Ag |
Purinski derivati za uporabo kot agonisti receptorja adenozina A A
|
|
ES2296516B1
(es)
*
|
2006-04-27 |
2009-04-01 |
Laboratorios Almirall S.A. |
Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
|
|
GB0611587D0
(en)
|
2006-06-12 |
2006-07-19 |
Glaxo Group Ltd |
Novel compounds
|
|
CL2007001829A1
(es)
|
2006-06-23 |
2008-01-25 |
Smithkline Beecham Corp |
P-toluensulfonato de n-[4-cloro-2-hidroxi-3-(piperazina-1-sulfonil)fenil]-n-(2-cloro-3-fluorofenil)urea;procedimiento de preparacion;composicion farmaceutica;combinacion farmaceutica;y uso en el tratamiento de una enfermedad mediada por la quiimioquina il-8, tales como asma y epoc.
|
|
HRP20110434T1
(hr)
|
2006-08-01 |
2011-08-31 |
Glaxo Group Limited |
Spojevi pirazolo[3,4-b]piridina i njihova upotreba kao inhibitora pde4
|
|
WO2008041914A1
(en)
*
|
2006-10-06 |
2008-04-10 |
Astrazeneca Ab |
5-(2-AMINO-L-HYDROXYETHYL)-8-HYDROXY-2-OXOQUINOLINE DERIVATIVES AND OTHER COMPOUNDS AS β2 -ADRENERGIC AGONISTS
|
|
MX2009006010A
(es)
*
|
2006-12-20 |
2009-06-16 |
Astrazeneca Ab |
Derivados de amina y su uso en enfermedades mediadas por el adrenoreceptor beta 2.
|
|
TW200833670A
(en)
|
2006-12-20 |
2008-08-16 |
Astrazeneca Ab |
Novel compounds 569
|
|
PL2104535T3
(pl)
|
2007-01-10 |
2011-05-31 |
Irm Llc |
Związki i kompozycje jako inhibitory proteazy aktywujące kanały
|
|
SA08280783B1
(ar)
*
|
2007-01-11 |
2011-04-24 |
استرازينيكا ايه بي |
مشتقات بيريدوبيريميدين كمثبطات pde4
|
|
GB0702458D0
(en)
|
2007-02-08 |
2007-03-21 |
Astrazeneca Ab |
Salts 668
|
|
JP2010518097A
(ja)
|
2007-02-09 |
2010-05-27 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
チャネル活性化プロテアーゼ阻害剤としての化合物および組成物
|
|
PE20081889A1
(es)
|
2007-03-23 |
2009-03-05 |
Smithkline Beecham Corp |
Indol carboxamidas como inhibidores de ikk2
|
|
AU2008248598B2
(en)
|
2007-05-07 |
2011-11-17 |
Novartis Ag |
Organic compounds
|
|
PL2444120T3
(pl)
|
2007-12-10 |
2018-02-28 |
Novartis Ag |
Spirocyklicze analogi amiloridu jako blokery ENac
|
|
JP5584138B2
(ja)
|
2008-01-11 |
2014-09-03 |
ノバルティス アーゲー |
キナーゼ阻害剤としてのピリミジン類
|
|
US20110160249A1
(en)
|
2008-05-23 |
2011-06-30 |
Schaab Kevin Murray |
5-lipoxygenase-activating protein inhibitor
|
|
JP5502858B2
(ja)
|
2008-06-05 |
2014-05-28 |
グラクソ グループ リミテッド |
Pi3キナーゼの阻害剤として有用な4−カルボキサミドインダゾール誘導体
|
|
KR20110040818A
(ko)
|
2008-06-10 |
2011-04-20 |
노파르티스 아게 |
상피 나트륨 채널 차단제로서의 피라진 유도체
|
|
JP2011524896A
(ja)
|
2008-06-18 |
2011-09-08 |
アストラゼネカ・アクチエボラーグ |
呼吸器障害の処置用のベータ2−アドレナリン受容体アゴニストとして作用するベンズオキサジノン誘導体
|
|
US8236786B2
(en)
|
2008-08-07 |
2012-08-07 |
Pulmagen Therapeutics (Inflammation) Limited |
Respiratory disease treatment
|
|
JP5555255B2
(ja)
|
2008-12-30 |
2014-07-23 |
プルマゲン セラピューティクス(インフラメーション)リミテッド |
呼吸器疾患の治療のためのスルホンアミド化合物
|
|
WO2010094643A1
(en)
|
2009-02-17 |
2010-08-26 |
Glaxo Group Limited |
Quinoline derivatives and their uses for rhinitis and urticaria
|
|
ES2542551T3
(es)
|
2009-03-09 |
2015-08-06 |
Glaxo Group Limited |
4-Oxadiazol-2-il-indazoles como inhibidores de PI3 cinasas
|
|
JP2012520257A
(ja)
|
2009-03-10 |
2012-09-06 |
グラクソ グループ リミテッド |
Ikk2阻害剤としてのインドール誘導体
|
|
EP2228368A1
(en)
|
2009-03-12 |
2010-09-15 |
Almirall, S.A. |
Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
|
|
JP2012520845A
(ja)
|
2009-03-17 |
2012-09-10 |
グラクソ グループ リミテッド |
Itk阻害剤として使用されるピリミジン誘導体
|
|
WO2010107952A2
(en)
|
2009-03-19 |
2010-09-23 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
CA2755773A1
(en)
|
2009-03-19 |
2010-09-23 |
Merck Sharp & Dohme Corp. |
Rna interference mediated inhibition of btb and cnc homology 1, basic leucine zipper transcription factor 1 (bach 1) gene expression using short interfering nucleic acid (sina)
|
|
JP2012520686A
(ja)
|
2009-03-19 |
2012-09-10 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたシグナル伝達性転写因子6(STAT6)遺伝子発現のRNA干渉媒介性阻害
|
|
JP2012520685A
(ja)
|
2009-03-19 |
2012-09-10 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたGATA結合タンパク質3(GATA3)遺伝子発現のRNA干渉媒介性阻害
|
|
JP2012521764A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いた胸腺間質性リンパ球新生因子(TSLP)遺伝子発現のRNA干渉媒介性阻害
|
|
US20120004281A1
(en)
|
2009-03-27 |
2012-01-05 |
Merck Sharp & Dohme Corp |
RNA Interference Mediated Inhibition of the Nerve Growth Factor Beta Chain (NGFB) Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
|
WO2010111464A1
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
JP2012521763A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いたシグナル伝達性転写因子1(STAT1)遺伝子発現のRNA干渉媒介性阻害
|
|
KR20110138223A
(ko)
|
2009-03-27 |
2011-12-26 |
머크 샤프 앤드 돔 코포레이션 |
짧은 간섭 핵산 (siNA)을 사용한 세포간 부착 분자 1 (ICAM-1) 유전자 발현의 RNA 간섭 매개 억제
|
|
EP2421834A1
(en)
|
2009-04-24 |
2012-02-29 |
Glaxo Group Limited |
Pyrazole and triazole carboxamides as crac channel inhibitors
|
|
UY32571A
(es)
|
2009-04-24 |
2010-11-30 |
Glaxo Group Ltd |
Compuestos derivados de pirazol amida
|
|
TWI516487B
(zh)
|
2009-04-30 |
2016-01-11 |
葛蘭素集團有限公司 |
新穎化合物、其醫藥組合物及作為激酶活性抑制劑之用途
|
|
WO2010150014A1
(en)
|
2009-06-24 |
2010-12-29 |
Pulmagen Therapeutics (Inflammation) Limited |
5r- 5 -deuterated glitazones for respiratory disease treatment
|
|
EP2490687A1
(en)
|
2009-10-22 |
2012-08-29 |
Vertex Pharmaceuticals Incorporated |
Compositions for treatment of cystic fibrosis and other chronic diseases
|
|
GB0918923D0
(en)
|
2009-10-28 |
2009-12-16 |
Vantia Ltd |
Aminothiazole derivatives
|
|
GB0918922D0
(en)
|
2009-10-28 |
2009-12-16 |
Vantia Ltd |
Aminopyridine derivatives
|
|
GB0918924D0
(en)
|
2009-10-28 |
2009-12-16 |
Vantia Ltd |
Azaindole derivatives
|
|
US20120245171A1
(en)
|
2009-12-03 |
2012-09-27 |
Glaxo Group Limited |
Benzpyrazole derivatives as inhibitors of pi3 kinases
|
|
WO2011067366A1
(en)
|
2009-12-03 |
2011-06-09 |
Glaxo Group Limited |
Indazole derivatives as pi 3 - kinase inhibitors
|
|
EP2507226A1
(en)
|
2009-12-03 |
2012-10-10 |
Glaxo Group Limited |
Novel compounds
|
|
EP3020393B1
(en)
|
2009-12-16 |
2020-10-07 |
3M Innovative Properties Company |
Formulations and methods for controlling mdi particle size delivery
|
|
WO2011098746A1
(en)
|
2010-02-09 |
2011-08-18 |
Pulmagen Therapeutics (Inflammation) Limited |
Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
|
|
GB201002224D0
(en)
|
2010-02-10 |
2010-03-31 |
Argenta Therapeutics Ltd |
Respiratory disease treatment
|
|
GB201002243D0
(en)
|
2010-02-10 |
2010-03-31 |
Argenta Therapeutics Ltd |
Respiratory disease treatment
|
|
WO2011110575A1
(en)
|
2010-03-11 |
2011-09-15 |
Glaxo Group Limited |
Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
|
|
US8247436B2
(en)
|
2010-03-19 |
2012-08-21 |
Novartis Ag |
Pyridine and pyrazine derivative for the treatment of CF
|
|
GB201007203D0
(en)
|
2010-04-29 |
2010-06-16 |
Glaxo Group Ltd |
Novel compounds
|
|
PL2614058T3
(pl)
|
2010-09-08 |
2015-12-31 |
Glaxosmithkline Ip Dev Ltd |
Polimorfy i sole n-[5-[4-(5-{[(2r,6s)-2,6-dimetylo-4-morfolinylo]-metylo}-1,3-oksazol-2-ilo)-1h-indazol-6-ilo]-2-(metyloksy)-3-pirydynylo]metanosulfonamidu
|
|
UY33597A
(es)
|
2010-09-09 |
2012-04-30 |
Irm Llc |
Compuestos y composiciones como inhibidores de la trk
|
|
WO2012034095A1
(en)
|
2010-09-09 |
2012-03-15 |
Irm Llc |
Compounds and compositions as trk inhibitors
|
|
US8372845B2
(en)
|
2010-09-17 |
2013-02-12 |
Novartis Ag |
Pyrazine derivatives as enac blockers
|
|
WO2012035055A1
(en)
|
2010-09-17 |
2012-03-22 |
Glaxo Group Limited |
Novel compounds
|
|
WO2012052458A1
(en)
|
2010-10-21 |
2012-04-26 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, immune and inflammatory conditions
|
|
US9149462B2
(en)
|
2010-10-21 |
2015-10-06 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, inflammatory and immune disorders
|
|
GB201018124D0
(en)
|
2010-10-27 |
2010-12-08 |
Glaxo Group Ltd |
Polymorphs and salts
|
|
GEP20156285B
(en)
|
2011-02-25 |
2015-05-11 |
Aierem Elelsi |
Compounds and compositions as trk inhibitors
|
|
GB201104153D0
(en)
|
2011-03-11 |
2011-04-27 |
Glaxo Group Ltd |
Novel compounds
|
|
JP2014507458A
(ja)
|
2011-03-11 |
2014-03-27 |
グラクソ グループ リミテッド |
Sykインヒビターとしてのピリド[3,4−B]ピラジン誘導体
|
|
UY34305A
(es)
|
2011-09-01 |
2013-04-30 |
Novartis Ag |
Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
|
|
JO3192B1
(ar)
|
2011-09-06 |
2018-03-08 |
Novartis Ag |
مركب بنزوثيازولون
|
|
WO2013038378A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine amide derivatives
|
|
WO2013038373A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine amide derivatives
|
|
ES2558457T3
(es)
|
2011-09-16 |
2016-02-04 |
Novartis Ag |
Compuestos heterocíclicos para el tratamiento de fibrosis quística
|
|
WO2013038381A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine/pyrazine amide derivatives
|
|
ES2882807T3
(es)
|
2011-09-16 |
2021-12-02 |
Novartis Ag |
Heterociclil carboxamidas N-sustituidas
|
|
EP2578570A1
(en)
|
2011-10-07 |
2013-04-10 |
Almirall, S.A. |
Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
|
|
US8809340B2
(en)
|
2012-03-19 |
2014-08-19 |
Novartis Ag |
Crystalline form
|
|
EP2641900A1
(en)
|
2012-03-20 |
2013-09-25 |
Almirall, S.A. |
Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
|
|
WO2014044288A1
(en)
*
|
2012-09-21 |
2014-03-27 |
Crystal Pharma Sa |
Methods for the preparation of indacaterol and pharmaceutically acceptable salts thereof
|
|
EP2897937B1
(en)
*
|
2012-09-21 |
2017-12-06 |
Crystal Pharma S.A.U |
Process for the preparation of indacaterol and intermediates thereof
|
|
US9073921B2
(en)
|
2013-03-01 |
2015-07-07 |
Novartis Ag |
Salt forms of bicyclic heterocyclic derivatives
|
|
CA2925064A1
(en)
|
2013-10-17 |
2015-04-23 |
Glaxosmithkline Intellectual Property Development Limited |
Pi3k inhibitor for treatment of respiratory disease
|
|
CA2923995A1
(en)
|
2013-10-17 |
2015-04-23 |
Glaxosmithkline Intellectual Property Development Limited |
Pi3k inhibitor for treatment of respiratory disease
|
|
US10112926B2
(en)
|
2014-04-24 |
2018-10-30 |
Novartis Ag |
Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors
|
|
CA2945212A1
(en)
|
2014-04-24 |
2015-10-29 |
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Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
|
|
EA033571B1
(ru)
|
2014-04-24 |
2019-11-06 |
Novartis Ag |
Производные пиразина в качестве ингибиторов фосфатидилинозитол 3-киназы
|
|
WO2015173701A2
(en)
|
2014-05-12 |
2015-11-19 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Pharmaceutical compositions for treating infectious diseases
|
|
WO2016027283A2
(en)
*
|
2014-08-22 |
2016-02-25 |
Reddy G Pratap |
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|
|
GB201602527D0
(en)
|
2016-02-12 |
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|
|
US20190161480A1
(en)
|
2016-08-08 |
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Glaxosmithkline Intellectual Property Development Limited |
Chemical Compounds
|
|
CN106478432A
(zh)
*
|
2016-08-29 |
2017-03-08 |
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|
|
CN106397228A
(zh)
*
|
2016-08-29 |
2017-02-15 |
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|
|
GB201706102D0
(en)
|
2017-04-18 |
2017-05-31 |
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|
|
GB201712081D0
(en)
|
2017-07-27 |
2017-09-13 |
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|
|
MX2021015133A
(es)
|
2019-06-10 |
2022-01-24 |
Novartis Ag |
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|
|
PE20220346A1
(es)
|
2019-08-28 |
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|