US20030176357A1
(en)
*
|
1998-10-06 |
2003-09-18 |
Pospisilik Andrew J. |
Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels
|
TWI249401B
(en)
*
|
1999-04-14 |
2006-02-21 |
Takeda Chemical Industries Ltd |
Agent for improving ketosis
|
PE20020323A1
(es)
*
|
2000-08-22 |
2002-06-13 |
Novartis Ag |
COMPOSICION FARMACEUTICA QUE COMPRENDE UN POTENCIADOR DE LA SECRESION DE INSULINA E INHIBIDORES DE HMG-Co-A-REDUCTASA O INHIBIDORES DE LA ENZIMA CONVERTIDORA DE ANGIOTENSINA (ACE)
|
US7166578B2
(en)
|
2000-08-24 |
2007-01-23 |
The Regents Of The University Of California |
Orally administered peptides synergize statin activity
|
US7723303B2
(en)
*
|
2000-08-24 |
2010-05-25 |
The Regents Of The University Of California |
Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
|
US7144862B2
(en)
*
|
2000-08-24 |
2006-12-05 |
The Regents Of The University Of California |
Orally administered peptides to ameliorate atherosclerosis
|
US8568766B2
(en)
|
2000-08-24 |
2013-10-29 |
Gattadahalli M. Anantharamaiah |
Peptides and peptide mimetics to treat pathologies associated with eye disease
|
US7199102B2
(en)
*
|
2000-08-24 |
2007-04-03 |
The Regents Of The University Of California |
Orally administered peptides synergize statin activity
|
US7148197B2
(en)
*
|
2000-08-24 |
2006-12-12 |
The Regents Of The University Of California |
Orally administered small peptides synergize statin activity
|
DE50111751D1
(de)
*
|
2000-12-21 |
2007-02-08 |
Sanofi Aventis Deutschland |
Neue diphenzylazetidinone, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung zur behandlung von lipidstoffwechselstörungen
|
US7025985B2
(en)
*
|
2001-05-28 |
2006-04-11 |
Kanebo, Ltd. |
Dihydroxyphenyl compounds and glucoside compounds thereof
|
JP4531335B2
(ja)
*
|
2001-05-28 |
2010-08-25 |
花王株式会社 |
脂肪分解促進剤及びそれを含有する痩身用皮膚化粧料、飲食品組成物並びにその作用に基づく痩身方法及び医薬用途
|
US6987123B2
(en)
|
2001-07-26 |
2006-01-17 |
Cadila Healthcare Limited |
Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
|
WO2003024395A2
(en)
|
2001-09-14 |
2003-03-27 |
Tularik Inc. |
Linked biaryl compounds
|
US20030220374A1
(en)
*
|
2002-01-14 |
2003-11-27 |
Pharmacia Corporation |
Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
|
TW200305415A
(en)
*
|
2002-03-22 |
2003-11-01 |
Novartis Ag |
Combination of organic compounds
|
US6716842B2
(en)
|
2002-04-05 |
2004-04-06 |
Warner-Lambert Company, Llc |
Antidiabetic agents
|
AU2003225027A1
(en)
*
|
2002-04-16 |
2003-11-03 |
Merck And Co., Inc. |
Combination therapy using a ppar alpha/gamma agonist
|
ITMI20021012A1
(it)
*
|
2002-05-13 |
2003-11-13 |
Giovanni Scaramuzzino |
Combinazione di un inibitore dell'enzima hmg-coa reduttasi e di un estere nitrato
|
EP1388352A1
(en)
*
|
2002-08-08 |
2004-02-11 |
Laboratoires Fournier S.A. |
Use of a ppar-alpha agonist to treat patients suffering from weight gain associated with a ppar-gamma agonist treatment
|
AU2003265681A1
(en)
|
2002-08-29 |
2004-03-19 |
Merck And Co., Inc. |
Indoles having anti-diabetic activity
|
WO2004019869A2
(en)
*
|
2002-08-29 |
2004-03-11 |
Merck & Co., Inc. |
Indoles having anti-diabetic activity
|
SI1539746T1
(sl)
*
|
2002-09-12 |
2007-04-30 |
Hoffmann La Roche |
Spojine n-substituirane-1h-indol-5-propionske kisline kot agonisti ppar, ki so uporabne za zdravljenje diabetesa
|
DE10300099A1
(de)
*
|
2003-01-07 |
2004-07-15 |
Bayer Healthcare Ag |
Indol-Phenylsulfonamid-Derivate
|
MXPA05007485A
(es)
|
2003-01-14 |
2006-01-30 |
Arena Pharm Inc |
Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia.
|
EP1590336B1
(en)
|
2003-01-27 |
2010-12-01 |
Merck Sharp & Dohme Corp. |
Substituted pyrazoles, compositions containing such compounds and methods of use
|
US20040248937A1
(en)
*
|
2003-04-14 |
2004-12-09 |
The Institute For Pharmaceutical Discovery Llc |
Substituted phenylalkanoic acids for the treatment of diabetes
|
EA200501710A1
(ru)
|
2003-04-30 |
2006-06-30 |
ДЗЕ ИНСТИТЬЮТС ФОР ФАРМАСЬЮТИКАЛ ДИСКАВЕРИ, ЭлЭлСи |
Замещённые карбоновые кислоты
|
US7981915B2
(en)
*
|
2003-04-30 |
2011-07-19 |
Beth Israel Deaconess Medical Center |
Methods for modulating PPAR biological activity for the treatment of diseases caused by mutations in the CFTR gene
|
WO2004098510A2
(en)
*
|
2003-04-30 |
2004-11-18 |
Beth Israel Deaconess Medical Center |
Cystic fibrosis therapy
|
US20050107387A1
(en)
*
|
2003-05-13 |
2005-05-19 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a peroxisome proliferator activated receptor agonist for the treatment of ischemic mediated central nervous system disorders
|
US20060160834A1
(en)
*
|
2003-06-06 |
2006-07-20 |
Fong Tung M |
Combination therapy for the treatment of hypertension
|
WO2004108126A1
(en)
*
|
2003-06-06 |
2004-12-16 |
Snowden Pharmaceuticals, Llc |
Fibric acid derivatives for the treatment of irritable bowel syndrome
|
AR045697A1
(es)
|
2003-07-14 |
2005-11-09 |
Arena Pharm Inc |
Aril y heteroaril derivados fusionados como moduladores del metabolismo y la prevencion y tratamiento de trastornos relacionados con el mismo
|
DE10335449A1
(de)
*
|
2003-08-02 |
2005-02-17 |
Bayer Healthcare Ag |
Bicyclische Indolinsulfonamid-Derivate
|
DE10337839A1
(de)
*
|
2003-08-18 |
2005-03-17 |
Bayer Healthcare Ag |
Indolin-Derivate
|
US20050074443A1
(en)
*
|
2003-10-03 |
2005-04-07 |
Treadwell Benjamin V. |
Methods of attenuating autoimmune disease and compositions useful therefor
|
BRPI0416238A
(pt)
*
|
2003-11-05 |
2007-01-02 |
Hoffmann La Roche |
compostos, processo para a sua preparação, composição farmacêutica que compreende os mesmos, uso dos compostos e métodos para o tratamento e/ou a prevenção de doenças que são moduladas por ppar(delta) e/ou agonistas ppar(alfa)
|
JP2007509998A
(ja)
|
2003-11-05 |
2007-04-19 |
エフ.ホフマン−ラ ロシュ アーゲー |
Ppar活性化剤としてのベンズ環付加された化合物
|
NZ546444A
(en)
*
|
2003-11-05 |
2009-09-25 |
Hoffmann La Roche |
Phenyl derivatives as PPAR agonists
|
CN1886133B
(zh)
|
2003-12-04 |
2010-12-01 |
财团法人卫生研究院 |
吲哚化合物
|
TWI297606B
(en)
*
|
2004-01-16 |
2008-06-11 |
Nat Health Research Institutes |
Cancer therapy
|
JP2007534702A
(ja)
*
|
2004-04-26 |
2007-11-29 |
バンダービルト・ユニバーシティ |
胃腸毒性の低い治療薬としてのインドール酢酸、及びインデン酢酸誘導体
|
US20080076810A1
(en)
*
|
2004-05-28 |
2008-03-27 |
Weiguo Lui |
Benzoureas Having Anti-Diabetic Activity
|
NZ551810A
(en)
*
|
2004-05-29 |
2010-09-30 |
7Tm Pharma As |
CRTH2 receptor ligands for medicinal uses
|
NZ551405A
(en)
*
|
2004-06-04 |
2009-06-26 |
Merck & Co Inc |
Pyrazole derivatives, compositions containing such compounds and methods of use
|
CN1980659A
(zh)
|
2004-07-02 |
2007-06-13 |
默克公司 |
具有抗糖尿病活性的吲哚类
|
US7625938B2
(en)
|
2004-07-22 |
2009-12-01 |
Merck & Co., Inc. |
Substituted pyrazoles, compositions containing such compounds and methods of use
|
KR20070058471A
(ko)
|
2004-07-30 |
2007-06-08 |
라보라토리오스 살바트, 에스.에이. |
Ppar-감마-조절자로서의 티로신 유도체
|
EP1799242A4
(en)
*
|
2004-09-16 |
2009-11-11 |
Univ California |
TYPE G PEPTIDES AND OTHER ACTIVE SUBSTANCES TO REDUCE ATHEROSCLEROSIS AND OTHER DISEASES
|
JP2008019169A
(ja)
*
|
2004-10-25 |
2008-01-31 |
Osaka Univ |
新規ppar調節剤およびそのスクリーニング方法
|
EP1844043A2
(en)
*
|
2004-11-18 |
2007-10-17 |
The Institutes for Pharmaceutical Discovery, LLC |
Heterocycle substituted carboxylic acids for the treatment of diabetes
|
RU2414236C2
(ru)
|
2004-12-06 |
2011-03-20 |
Зе Риджентс Оф Зи Юнивесити Оф Кэлифонье |
Способ улучшения структуры и/или функций артериол
|
DOP2006000008A
(es)
*
|
2005-01-10 |
2006-08-31 |
Arena Pharm Inc |
Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
|
FR2880887B1
(fr)
*
|
2005-01-14 |
2009-01-30 |
Merck Sante Soc Par Actions Si |
Derives d'hydroxyphenols, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique
|
US7834036B2
(en)
|
2005-03-04 |
2010-11-16 |
Merck Sharp & Dohme Corp |
Fused-aromatic compounds having anti-diabetic activity
|
US20080293639A1
(en)
*
|
2005-04-29 |
2008-11-27 |
The Regents Of The University Of California |
Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
|
MX2007013430A
(es)
*
|
2005-04-29 |
2008-03-19 |
Univ California |
Peptidos y peptidos mimeticos para tratar patologias caracterizadas por una respuesta inflamatoria.
|
JP2008542226A
(ja)
*
|
2005-05-24 |
2008-11-27 |
ディーエスエム アイピー アセッツ ビー.ブイ. |
炎症性障害の治療のためのリグスチリド誘導体
|
US7807692B2
(en)
|
2005-07-06 |
2010-10-05 |
Merck Sharp & Dohme Corp. |
Antidiabetic oxazolidinediones and thiazolidinediones
|
AU2006276072A1
(en)
|
2005-07-26 |
2007-02-08 |
Merck Sharp & Dohme Corp. |
Process for synthesizing a substituted pyrazole
|
US20070161006A1
(en)
*
|
2006-01-10 |
2007-07-12 |
Vita Genomics, Inc. |
Single nucleotide polymorphisms in protein-tyrosine phosphatase receptor-type delta for the diagnosis of susceptibility to infection and asthma
|
DE602007010420D1
(de)
*
|
2006-04-11 |
2010-12-23 |
Arena Pharm Inc |
Verfahren zur verwendung des gpr119-rezeptors zur identifizierung von verbindungen zur erhöhung der knochenmasse bei einer person
|
PE20071221A1
(es)
*
|
2006-04-11 |
2007-12-14 |
Arena Pharm Inc |
Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
|
CN101528222A
(zh)
|
2006-06-19 |
2009-09-09 |
范德比尔特大学 |
用于诊断性和治疗性靶向cox-2的方法和组合物
|
CA2663121C
(en)
|
2006-09-08 |
2016-01-19 |
Rhode Island Hospital |
Treatment, prevention, and reversal of alcohol-induced brain disease
|
NZ578296A
(en)
|
2007-01-26 |
2012-07-27 |
Kaneq Pharma Inc |
Fused aromatic ptp-1b inhibitors
|
AU2008221194B2
(en)
|
2007-02-26 |
2013-06-27 |
Merck Canada Inc. |
Indole and indoline cyclopropyl amide derivatives as EP4 receptor antagonists
|
CA2688187C
(en)
|
2007-05-07 |
2016-10-11 |
Merck & Co., Inc. |
Method of treament using fused aromatic compounds having anti-diabetic activity
|
US20080319221A1
(en)
*
|
2007-06-22 |
2008-12-25 |
Bernd Junker |
Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids
|
US20080319218A1
(en)
*
|
2007-06-22 |
2008-12-25 |
Andreas Haubrich |
Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate
|
JP2010538005A
(ja)
|
2007-08-28 |
2010-12-09 |
ユーエービー リサーチ ファウンデーション |
合成アポリポ蛋白質e模倣ポリペプチドおよび使用方法
|
WO2009032702A2
(en)
|
2007-08-28 |
2009-03-12 |
Uab Research Foundation |
Synthetic apolipoprotein e mimicking polypeptides and methods of use
|
FR2921366B1
(fr)
*
|
2007-09-26 |
2009-12-04 |
Servier Lab |
Nouveaux derives heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
DE102007054497B3
(de)
*
|
2007-11-13 |
2009-07-23 |
Sanofi-Aventis Deutschland Gmbh |
Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
|
EP2108960A1
(en)
|
2008-04-07 |
2009-10-14 |
Arena Pharmaceuticals, Inc. |
Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
|
JO2870B1
(en)
|
2008-11-13 |
2015-03-15 |
ميرك شارب اند دوهم كورب |
Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes
|
CA2743489A1
(en)
|
2008-11-17 |
2010-05-20 |
Merck Sharp & Dohme Corp. |
Substituted bicyclic amines for the treatment of diabetes
|
TW201028414A
(en)
|
2009-01-16 |
2010-08-01 |
Merck Sharp & Dohme |
Oxadiazole beta carboline derivatives as antidiabetic compounds
|
AU2010206786A1
(en)
|
2009-01-23 |
2011-07-28 |
Merck Sharp & Dohme Corp. |
Bridged and fused heterocyclic antidiabetic compounds
|
JP2012515782A
(ja)
|
2009-01-23 |
2012-07-12 |
シェーリング コーポレイション |
抗糖尿病性架橋および縮合化合物
|
AR075051A1
(es)
|
2009-02-05 |
2011-03-02 |
Schering Corp |
Compuestos antidiabeticos que contienen ftalazina
|
CA2768577A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Benzo-fused oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
WO2011011506A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Spirocyclic oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
US8552022B2
(en)
|
2009-08-13 |
2013-10-08 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
IN2012DN00721A
(US06525083-20030225-C00031.png)
|
2009-09-02 |
2015-06-19 |
Merck Sharp & Dohme |
|
CA2785790A1
(en)
|
2010-01-15 |
2011-07-21 |
Merck Sharp & Dohme Corp. |
Oxadiazole beta carboline derivatives as antidiabetic compounds
|
US8853212B2
(en)
|
2010-02-22 |
2014-10-07 |
Merck Sharp & Dohme Corp |
Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes
|
EP2563764B1
(en)
|
2010-04-26 |
2015-02-25 |
Merck Sharp & Dohme Corp. |
Novel spiropiperidine prolylcarboxypeptidase inhibitors
|
US9365539B2
(en)
|
2010-05-11 |
2016-06-14 |
Merck Sharp & Dohme Corp. |
Prolylcarboxypeptidase inhibitors
|
WO2011146358A1
(en)
|
2010-05-21 |
2011-11-24 |
Merck Sharp & Dohme Corp. |
Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
EP2579873A4
(en)
|
2010-06-11 |
2013-11-27 |
Merck Sharp & Dohme |
NOVEL PROLYLCARBOXYPEPTIDASE HEMMER
|
EP2605658B1
(en)
|
2010-08-18 |
2016-03-23 |
Merck Sharp & Dohme Corp. |
Spiroxazolidinone compounds
|
JP5941916B2
(ja)
|
2010-09-22 |
2016-06-29 |
アリーナ ファーマシューティカルズ, インコーポレイテッド |
Gpr119レセプターのモジュレーターおよびそれに関連する障害の処置
|
WO2012058203A1
(en)
|
2010-10-29 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
Diazeniumdiolate heterocyclic derivatives
|
WO2012097744A1
(en)
|
2011-01-20 |
2012-07-26 |
Merck Sharp & Dohme Corp. |
Mineralocorticoid receptor antagonists
|
JO3350B1
(ar)
|
2011-03-07 |
2019-03-13 |
Merck Sharp & Dohme |
مشتقات حلقية غير متجانسة محتوية على مجموعات أمينو أولية ومركبات داي أزينيومديولات
|
EP2693882B1
(en)
|
2011-04-08 |
2017-06-28 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
US9487506B2
(en)
|
2011-04-13 |
2016-11-08 |
Merck Sharp & Dohme Corp. |
Mineralocorticoid receptor antagonists
|
WO2012151114A1
(en)
|
2011-05-02 |
2012-11-08 |
Merck Sharp & Dohme Corp. |
Diazeniumdiolate cyclohexyl derivatives
|
BR112013030883A2
(pt)
|
2011-06-02 |
2017-10-10 |
Intervet Int Bv |
composto, composição farmacêutica, uso do composto, e, método para o tratamento de uma condição selecionada do grupo consistindo em obesidade e diabete
|
WO2012173917A1
(en)
|
2011-06-16 |
2012-12-20 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds, and methods of treatment
|
WO2012178142A1
(en)
*
|
2011-06-23 |
2012-12-27 |
Metabolic Solutions Development Company, Llc |
Ppar-sparing compounds and combinations fort the treatment of diabetes and other metabolic diseases
|
EP2760855B1
(en)
|
2011-09-30 |
2017-03-15 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds as well as their use in treating type-2 diabetes
|
WO2013055606A1
(en)
|
2011-10-13 |
2013-04-18 |
Merck Sharp & Dohme Corp. |
Mineralocorticoid receptor antagonists
|
EP3078374B1
(en)
|
2011-10-17 |
2019-06-19 |
Vanderbilt University |
Indomethacin analogs for the treatment of castrate-resistant prostate cancer
|
EP2771000B1
(en)
|
2011-10-24 |
2016-05-04 |
Merck Sharp & Dohme Corp. |
Substituted piperidinyl compounds useful as gpr119 agonists
|
JO3210B1
(ar)
|
2011-10-28 |
2018-03-08 |
Merck Sharp & Dohme |
مثبط منصهر لبروتين نقل الكوليسترليستير اوكسازوليدينون ثمائي الحلقة
|
WO2013068328A1
(en)
|
2011-11-07 |
2013-05-16 |
Intervet International B.V. |
Bicyclo [2.2.2] octan-1-ylcarboxylic acid compounds as dgat-1 inhibitors
|
WO2013068439A1
(en)
|
2011-11-09 |
2013-05-16 |
Intervet International B.V. |
4-amino-5-oxo-7,8-dihydropyrimido[5, 4 -f] [1, 4] oxazepine compounds as dgat1 inhibitors
|
WO2013074388A1
(en)
|
2011-11-15 |
2013-05-23 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds useful as gpr119 agonists
|
US9073930B2
(en)
|
2012-02-17 |
2015-07-07 |
Merck Sharp & Dohme |
Dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
|
IN2014DN09640A
(US06525083-20030225-C00031.png)
|
2012-04-16 |
2015-07-31 |
Kaneq Pharma Inc |
|
US9315508B2
(en)
|
2012-07-23 |
2016-04-19 |
Merck Sharp & Dohme Corp. |
Treating diabetes with dipeptidyl peptidase-IV inhibitors
|
US9453038B2
(en)
|
2012-12-17 |
2016-09-27 |
Merck Sharp & Dohme Corp. |
Glucokinase activator compounds, compositions containing such compounds, and methods of treatment
|
US9717714B2
(en)
|
2012-12-19 |
2017-08-01 |
Merck Sharp & Dohme Corp. |
Spirocyclic CETP inhibitors
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
WO2015089809A1
(en)
|
2013-12-19 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Antidiabetic substituted heteroaryl compounds
|
EP3097101B1
(en)
|
2014-01-24 |
2020-12-23 |
Merck Sharp & Dohme Corp. |
Isoquinoline derivatives as mgat2 inhibitors
|
WO2015176267A1
(en)
|
2014-05-22 |
2015-11-26 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
WO2016018729A1
(en)
|
2014-07-29 |
2016-02-04 |
Merck Sharp & Dohme Corp. |
Monocyclic isoxazolines as inhibitors of cholesterol ester transfer protein
|
JP7081923B2
(ja)
|
2014-07-31 |
2022-06-07 |
ユーエイビー リサーチ ファンデーション |
アポe模倣ペプチド及び血漿コレステロールを取り除くためのより高い効果
|
US10100042B2
(en)
|
2014-08-08 |
2018-10-16 |
Merck Sharp & Dohme Corp. |
[5,6]—fused bicyclic antidiabetic compounds
|
EP3177287B1
(en)
|
2014-08-08 |
2022-02-23 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
US10662171B2
(en)
|
2014-08-08 |
2020-05-26 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
US10413593B2
(en)
|
2014-10-24 |
2019-09-17 |
Merck Sharp & Dohme Corp. |
Co-agonists of the glucagon and GLP-1 receptors
|
TW201625635A
(zh)
|
2014-11-21 |
2016-07-16 |
默沙東藥廠 |
作為可溶性鳥苷酸環化酶活化劑之三唑并吡基衍生物
|
JP6895378B2
(ja)
|
2015-01-06 |
2021-06-30 |
アリーナ ファーマシューティカルズ, インコーポレイテッド |
S1p1受容体に関連する状態の処置方法
|
WO2016191334A1
(en)
|
2015-05-27 |
2016-12-01 |
Merck Sharp & Dohme Corp. |
Imidazo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
|
US10213429B2
(en)
|
2015-05-28 |
2019-02-26 |
Merck Sharp & Dohme Corp. |
Imidazo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
|
EP3939965A1
(en)
|
2015-06-22 |
2022-01-19 |
Arena Pharmaceuticals, Inc. |
Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid for use in sipi receptor-associated disorders
|
EP3322420B1
(en)
|
2015-07-13 |
2021-12-29 |
Merck Sharp & Dohme Corp. |
Bicyclic heterocycles as inhibitors of cholesterol ester transfer protein
|
US10800826B2
(en)
|
2015-10-05 |
2020-10-13 |
Merck Sharp & Dohme Corp. |
Antibody peptide conjugates that have agonist activity at both the glucagon and glucagon-like peptide 1 receptors
|
US10450309B2
(en)
|
2015-11-30 |
2019-10-22 |
Merch Sharp & Dohme Corp. |
Aryl sulfonamides as BLT1 antagonists
|
WO2017095724A1
(en)
|
2015-11-30 |
2017-06-08 |
Merck Sharp & Dohme Corp. |
Aryl sulfonamides as blt1 antagonists
|
WO2017107052A1
(en)
|
2015-12-22 |
2017-06-29 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase stimulators
|
WO2017197555A1
(en)
|
2016-05-16 |
2017-11-23 |
Merck Sharp & Dohme Corp. |
Fused pyrazine derivatives useful as soluble guanylate cyclase stimulators
|
WO2017201683A1
(en)
|
2016-05-25 |
2017-11-30 |
Merck Sharp & Dohme Corp. |
Substituted tetrahydroisoquinoline compounds useful as gpr120 agonists
|
US10414774B2
(en)
|
2016-08-15 |
2019-09-17 |
Merck Sharp & Dohme Corp. |
Compound useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolc disease
|
WO2018034917A1
(en)
|
2016-08-15 |
2018-02-22 |
Merck Sharp & Dohme Corp. |
Compounds useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolic disease
|
WO2018057409A1
(en)
|
2016-09-20 |
2018-03-29 |
Merck Sharp & Dohme Corp. |
Substituted 1-methyl-1,2,3,4-tetrahydroisoquinoline molecules as pcsk9 allosteric binders
|
RU2019117958A
(ru)
|
2016-11-18 |
2020-12-18 |
Мерк Шарп И Доум Корп. |
Производные индола, полезные в качестве ингибиторов диацилглицерид-о-ацилтрансферазы 2
|
WO2018107415A1
(en)
|
2016-12-15 |
2018-06-21 |
Merck Sharp & Dohme Corp. |
Hydroxy isoxazole compounds useful as gpr120 agonists
|
CN110520124A
(zh)
|
2017-02-16 |
2019-11-29 |
艾尼纳制药公司 |
用于治疗原发性胆汁性胆管炎的化合物和方法
|
JOP20190150A1
(ar)
|
2018-06-21 |
2019-12-21 |
Merck Sharp & Dohme |
مركبات مناهضة لـ pcsk9
|
WO2020205688A1
(en)
|
2019-04-04 |
2020-10-08 |
Merck Sharp & Dohme Corp. |
Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes
|
WO2020236688A1
(en)
|
2019-05-22 |
2020-11-26 |
Merck Sharp & Dohme Corp. |
Natriuretic peptide receptor a agonists useful for the treatment of cardiometabolic diseases, kidney disease and diabetes
|
EP3972589A4
(en)
|
2019-05-22 |
2023-04-26 |
Merck Sharp & Dohme LLC |
NATRIURETIC PEPTIDE RECEPTOR A AGONISTS USED TO TREAT CARDIOMETABOLIC DISEASES, KIDNEY DISEASES AND DIABETES
|
WO2021041770A1
(en)
|
2019-08-30 |
2021-03-04 |
Merck Sharp & Dohme Corp. |
Pcsk9 antagonist compounds
|
EP3842449A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled olefin co-agonists of the glucagon and glp-1 receptors
|
EP3842060A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled lactam co-agonists of the glucagon and glp-1 receptors
|
EP3842061A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled triazole co-agonists of the glucagon and glp-1 receptors
|
EP4153596A1
(en)
|
2020-05-18 |
2023-03-29 |
Merck Sharp & Dohme LLC |
Novel diacylglyceride o-acyltransferase 2 inhibitors
|
IL310851A
(en)
|
2021-08-19 |
2024-04-01 |
Merck Sharp & Dohme Llc |
Compounds for the treatment of diseases associated with PCSK9 activity
|
TW202404574A
(zh)
|
2022-06-15 |
2024-02-01 |
美商默沙東有限責任公司 |
用於捕捉介白素-1 β之環狀肽
|