AU2001276522A1 - The use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands - Google Patents
The use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligandsInfo
- Publication number
- AU2001276522A1 AU2001276522A1 AU2001276522A AU7652201A AU2001276522A1 AU 2001276522 A1 AU2001276522 A1 AU 2001276522A1 AU 2001276522 A AU2001276522 A AU 2001276522A AU 7652201 A AU7652201 A AU 7652201A AU 2001276522 A1 AU2001276522 A1 AU 2001276522A1
- Authority
- AU
- Australia
- Prior art keywords
- hydroxyguanidine tosylate
- nitrobenzylideneamino
- hydroxyguanidine
- tosylate
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/46—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
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- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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GB0019357A GB0019357D0 (en) | 2000-08-07 | 2000-08-07 | Novel phenyl guanidines |
GB0019357 | 2000-08-07 | ||
PCT/GB2001/003534 WO2002011715A2 (en) | 2000-08-07 | 2001-08-07 | The use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands |
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AU2001276522A1 true AU2001276522A1 (en) | 2002-02-18 |
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Family Applications (1)
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AU2001276522A Abandoned AU2001276522A1 (en) | 2000-08-07 | 2001-08-07 | The use of benzylideneaminoguanidines and hydroxyguanidines as melanocortin receptor ligands |
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Country | Link |
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US (6) | US20040024060A1 (pt) |
EP (1) | EP1313461A2 (pt) |
JP (2) | JP5654190B2 (pt) |
KR (1) | KR100929363B1 (pt) |
AU (1) | AU2001276522A1 (pt) |
BR (1) | BR0113053A (pt) |
CA (1) | CA2417098A1 (pt) |
GB (1) | GB0019357D0 (pt) |
IL (2) | IL154272A0 (pt) |
MX (1) | MXPA03001072A (pt) |
WO (1) | WO2002011715A2 (pt) |
ZA (1) | ZA200300829B (pt) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001269092A1 (en) * | 2000-06-27 | 2002-01-08 | Axxima Pharmaceuticals Ag | Inhibitors of hepatitis b virus infection |
GB0019357D0 (en) * | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel phenyl guanidines |
GB0108631D0 (en) * | 2001-04-05 | 2001-05-30 | Melacure Therapeutics Ab | Novel benzylideneamino guanidines and their uses as ligands to the melanocortin receptors |
GB0119172D0 (en) * | 2001-08-06 | 2001-09-26 | Melacure Therapeutics Ab | Phenyl pyrrole derivatives |
US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
AU2002336638A1 (en) * | 2001-10-12 | 2003-04-28 | Cornell Research Foundation, Inc. | Reversing or preventing premature vascular senescence |
WO2003072056A2 (en) * | 2002-02-25 | 2003-09-04 | Chiron Corporation | Intranasal administration of mc4-r agonists |
US7105526B2 (en) | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US7547693B2 (en) | 2003-09-22 | 2009-06-16 | Banyu Pharmaceutical Co. Ltd. | Piperidine derivative |
US20080125403A1 (en) | 2004-04-02 | 2008-05-29 | Merck & Co., Inc. | Method of Treating Men with Metabolic and Anthropometric Disorders |
US7737155B2 (en) | 2005-05-17 | 2010-06-15 | Schering Corporation | Nitrogen-containing heterocyclic compounds and methods of use thereof |
US8138206B2 (en) | 2005-05-30 | 2012-03-20 | Msd. K.K. | Piperidine derivative |
WO2007018248A1 (ja) | 2005-08-10 | 2007-02-15 | Banyu Pharmaceutical Co., Ltd. | ピリドン化合物 |
WO2007024004A1 (ja) | 2005-08-24 | 2007-03-01 | Banyu Pharmaceutical Co., Ltd. | フェニルピリドン誘導体 |
JPWO2007029847A1 (ja) | 2005-09-07 | 2009-03-19 | 萬有製薬株式会社 | 二環性芳香族置換ピリドン誘導体 |
KR20080048502A (ko) | 2005-09-29 | 2008-06-02 | 머크 앤드 캄파니 인코포레이티드 | 멜라노코르틴-4 수용체 조절제로서의 아실화스피로피페리딘 유도체 |
WO2007048027A2 (en) | 2005-10-21 | 2007-04-26 | Novartis Ag | Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent |
US8163770B2 (en) | 2005-10-27 | 2012-04-24 | Msd. K. K. | Benzoxathiin derivative |
WO2007055418A1 (ja) | 2005-11-10 | 2007-05-18 | Banyu Pharmaceutical Co., Ltd. | アザ置換スピロ誘導体 |
DK2348016T3 (en) | 2006-06-09 | 2016-05-30 | Synact Pharma Aps | Phenylpyrrolaminoguanidine derivatives |
WO2008039327A2 (en) | 2006-09-22 | 2008-04-03 | Merck & Co., Inc. | Method of treatment using fatty acid synthesis inhibitors |
AU2007301126A1 (en) | 2006-09-28 | 2008-04-03 | Banyu Pharmaceutical Co., Ltd. | Diaryl ketimine derivative |
GB0623381D0 (en) * | 2006-11-23 | 2007-01-03 | Acure Pharma Ab | Use of a compound as VEGF inhibitor |
GB0624987D0 (en) | 2006-12-14 | 2007-01-24 | Acure Pharma Ab | Novel aminoguanidines as melanocortin receptor ligands |
AU2007339954B2 (en) | 2006-12-26 | 2013-06-20 | Lantheus Medical Imaging, Inc. | Ligands for imaging cardiac innervation |
JP5319518B2 (ja) | 2007-04-02 | 2013-10-16 | Msd株式会社 | インドールジオン誘導体 |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
ES2393885T7 (es) | 2007-06-04 | 2014-01-30 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
US8442179B2 (en) * | 2007-10-19 | 2013-05-14 | The Boeing Company | Method and apparatus for tagging and identifying a target |
US20110213021A1 (en) * | 2008-03-04 | 2011-09-01 | Indigene Pharmaceuticals, Inc. | Compositions and methods for treating nos-associated diseases |
JPWO2009110510A1 (ja) | 2008-03-06 | 2011-07-14 | Msd株式会社 | アルキルアミノピリジン誘導体 |
CN101981025A (zh) | 2008-03-28 | 2011-02-23 | 万有制药株式会社 | 具有黑色素浓缩激素受体拮抗作用的二芳基甲基酰胺衍生物 |
AU2009261248A1 (en) | 2008-06-19 | 2009-12-23 | Banyu Pharmaceutical Co., Ltd. | Spirodiamine-diarylketoxime derivative |
AU2009270833B2 (en) | 2008-07-16 | 2015-02-19 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
WO2010013595A1 (ja) | 2008-07-30 | 2010-02-04 | 萬有製薬株式会社 | 5員-5員又は5員-6員縮環シクロアルキルアミン誘導体 |
MX2011004258A (es) | 2008-10-22 | 2011-06-01 | Merck Sharp & Dohme | Derivados de bencimidazol ciclicos novedosos utiles como agentes anti-diabeticos. |
CA2741672A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
US20110243940A1 (en) | 2008-12-16 | 2011-10-06 | Schering Corporation | Bicyclic pyranone derivatives and methods of use thereof |
EP2379547A1 (en) | 2008-12-16 | 2011-10-26 | Schering Corporation | Pyridopyrimidine derivatives and methods of use thereof |
WO2010109192A1 (en) | 2009-03-24 | 2010-09-30 | Anamar Ab | Metabolic profiles |
CN102573993A (zh) * | 2009-07-31 | 2012-07-11 | Anamar股份公司 | 治疗炎症的化合物 |
CN113058046A (zh) | 2010-02-08 | 2021-07-02 | 兰休斯医疗成像公司 | 用于合成显像剂和其中间体的方法和装置 |
CA2786314A1 (en) | 2010-02-25 | 2011-09-01 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
BR122020018186B1 (pt) | 2010-05-11 | 2021-07-27 | Lantheus Medical Imaging, Inc | Uso de agentes de imagiologia para preparação de uma composição para detecção do transportador de norepinefrina (net) e método para a detecção de net |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
KR101668514B1 (ko) | 2011-02-25 | 2016-10-21 | 머크 샤프 앤드 돔 코포레이션 | 항당뇨병제로서 유용한 신규 시클릭 아자벤즈이미다졸 유도체 |
SG2014013767A (en) * | 2011-09-09 | 2014-05-29 | Lantheus Medical Imaging Inc | Compositions, methods, and systems for the synthesis and use of imaging agents |
JP2015525782A (ja) | 2012-08-02 | 2015-09-07 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 抗糖尿病性三環式化合物 |
AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
GB201300435D0 (en) * | 2013-01-10 | 2013-02-27 | Medical Res Council | Benzylideneguanidine Derivatives and Therapeutic Use for the Treatment of Protein Misfolding Diseases |
RU2015140066A (ru) | 2013-02-22 | 2017-03-30 | Мерк Шарп И Доум Корп. | Противодиабетические бициклические соединения |
US9650375B2 (en) | 2013-03-14 | 2017-05-16 | Merck Sharp & Dohme Corp. | Indole derivatives useful as anti-diabetic agents |
CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
JP2016514671A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼのアゴニストおよびその使用 |
US10011637B2 (en) | 2013-06-05 | 2018-07-03 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
EP3721877A1 (en) * | 2014-07-02 | 2020-10-14 | InFlectis BioScience | Novel therapeutic uses of benzylideneguanidine derivatives for the treatment of proteopathies |
PT3164391T (pt) * | 2014-07-02 | 2019-10-29 | Inflectis Bioscience | Derivados de o-alquil-benzilidenoguanidina e utilização terapêutica para o tratamento de distúrbios associados com uma acumulação de proteínas mal enroladas |
MX2017002610A (es) | 2014-08-29 | 2017-10-11 | Tes Pharma S R L | INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA. |
CA2982033C (en) | 2015-04-08 | 2024-01-02 | Medical Research Council | Methods for selecting phosphatase selective and non-selective phosphatase inhibitors |
US20180134667A1 (en) | 2016-10-14 | 2018-05-17 | TES Pharma S.r.I. | Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase |
WO2018106518A1 (en) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
US10968232B2 (en) | 2016-12-20 | 2021-04-06 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
US20180230105A1 (en) | 2017-01-13 | 2018-08-16 | Regents Of The University Of Minnesota | Therapeutic compounds |
CN108066763A (zh) * | 2017-12-21 | 2018-05-25 | 陈敏 | Pcsk9抑制剂在制备治疗t细胞介导的炎症免疫性疾病药中的应用 |
EP3790539A1 (en) * | 2018-05-09 | 2021-03-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of guanabenz or derivates thereof for the treatment of type i ifn-dependent pathologies |
MX2021005904A (es) | 2018-11-20 | 2021-09-08 | Tes Pharma S R L | Inhibidores de la ácido alfa-amino-beta-carboximucónico semialdehído descarboxilasa. |
Family Cites Families (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2584784A (en) * | 1949-05-21 | 1952-02-05 | Du Pont | Salts of 1-salicylalaminoguanidine |
GB892117A (en) | 1958-06-20 | 1962-03-21 | May & Baker Ltd | Phenanthridine salts and their preparation |
DE1165013B (de) | 1960-08-09 | 1964-03-12 | Vismara Francesco Spa | Verfahren zur Herstellung von Guanylhydrazonen |
GB923398A (en) | 1960-08-09 | 1963-04-10 | Vismara Francesco Spa | Diphenyl mono-and bis-formyl guanylhydrazones |
GB1019120A (en) | 1964-03-18 | 1966-02-02 | Shell Int Research | Novel hydrazine compounds and compositions containing them |
FR7689M (pt) | 1967-10-12 | 1970-02-16 | ||
GB1223491A (en) | 1967-10-13 | 1971-02-24 | American Home Prod | Guanidines |
CH500953A (de) | 1967-11-13 | 1970-12-31 | Sandoz Ag | Verfahren zur Herstellung von neuen N-Benzyliden-N'-amidinohydrazinen |
US3591636A (en) * | 1968-09-16 | 1971-07-06 | Sandoz Ag | Substituted benzylideneamino guanidines |
GB1223493A (en) | 1968-10-11 | 1971-02-24 | American Home Prod | Guanidines |
US3592852A (en) * | 1968-12-16 | 1971-07-13 | Sandoz Ag | Substituted benzylideneamino guanidine |
DE2015321A1 (en) | 1969-04-04 | 1970-10-08 | Sandoz Ag, Basel (Schweiz) | Novel guanidine derivs |
FR2036989A1 (en) * | 1969-04-28 | 1970-12-31 | Anvar | Amidino hydrazone antivirals |
US3541218A (en) * | 1969-06-18 | 1970-11-17 | Lilly Co Eli | Omicron-fluorobenzylaminoguanidine for diabetes |
US3592935A (en) * | 1969-12-11 | 1971-07-13 | Sandoz Ag | Substituted benzylidene hydrazines as anti-inflammatory agents |
US3982020A (en) * | 1970-03-17 | 1976-09-21 | Sandoz, Inc. | Substituted benzylidene hydrazines for treating hyperglycemia, obesity and inflammation |
US3975533A (en) * | 1970-04-29 | 1976-08-17 | Shell Oil Company | Therapeutic agents |
US4060640A (en) * | 1970-04-29 | 1977-11-29 | Shell Oil Company | Therapeutic agents |
JPS4842969B1 (pt) | 1970-12-30 | 1973-12-15 | ||
BE791536A (fr) * | 1971-11-19 | 1973-05-17 | Merck & Co Inc | Nouvelles 1,3-diamino guanidines substituees |
US3896232A (en) * | 1973-01-11 | 1975-07-22 | Sandoz Ag | Substituted benzylidene hydrazines as anti-migraine syndrome agents |
US3941825A (en) * | 1973-07-27 | 1976-03-02 | American Cyanamid Company | Substituted aminobenzylideneamino guanidine compounds |
US4006249A (en) * | 1975-08-06 | 1977-02-01 | American Home Products Corporation | Systemic treatment of psoriasis |
US4006250A (en) * | 1975-08-25 | 1977-02-01 | American Home Products Corporation | Systemic treatment of psoriasis |
FR2324294A1 (fr) | 1975-09-22 | 1977-04-15 | Roussel Uclaf | Nouveau medicament hypotenseur a action retardee, ainsi que le procede de preparation de ce nouveau medicament |
GB1550401A (en) * | 1976-01-07 | 1979-08-15 | Hexachimie | Hydrazine derivatives their preparation and their use |
DE2620369C3 (de) | 1976-05-08 | 1979-01-04 | Bayer Ag, 5090 Leverkusen | Verfahren zur Wiedergewinnung von (l-S)-2-Oxo-bornansulfonat-(10) |
US4312886A (en) * | 1978-07-20 | 1982-01-26 | American Home Products Corporation | Prevention of gastric ulcers and depression of gastric secretion by administration of guanabenz |
JPS5562017A (en) | 1978-11-01 | 1980-05-10 | Teijin Ltd | Anti-inflammatory agent comprising guanidine derivative |
US5958933A (en) * | 1982-11-23 | 1999-09-28 | Naftchi; N. Eric | Neurologically active compounds and compounds with multiple activities |
US4983604A (en) | 1987-11-13 | 1991-01-08 | The Rockefeller University | Inhibitors of nonenzymatic cross-linking |
ZA853488B (en) | 1984-05-10 | 1986-12-30 | American Home Prod | Transdermal dosage form |
DE3428342A1 (de) * | 1984-08-01 | 1986-02-13 | Boehringer Ingelheim Vetmedica GmbH, 6507 Ingelheim | Futtermittelzusatz zur verbesserung des wachstums bei landwirtschaftlichen nutztieren |
US6413962B1 (en) * | 1988-05-02 | 2002-07-02 | N. Eric Naftchi | Guanidino compounds effective as anesthetics |
DE69130216T2 (de) | 1990-03-16 | 1999-03-25 | Beth Israel Hospital | Verwendung von spiperon als immunsuppressivum und antiinflammatorisches mittel |
EP0573581A4 (en) | 1991-02-26 | 1994-06-29 | Arc 1 Inc | Compositions and methods of treatment of sympathetically maintained pain |
HUT64023A (en) | 1991-03-22 | 1993-11-29 | Sandoz Ag | Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds |
CA2113817A1 (en) * | 1991-08-27 | 1993-02-04 | Jerry R. Colca | A method for treatment of metabolic disorders |
US5696128A (en) | 1994-07-07 | 1997-12-09 | The Board Of Supervisors Of Louisiana University And Agricultural And Mechanical College | Method of regulating immune function |
US5750545A (en) * | 1993-07-23 | 1998-05-12 | The Green Cross Corporation | Triazole derivative and pharmaceutical use thereof |
US5599984A (en) * | 1994-01-21 | 1997-02-04 | The Picower Institute For Medical Research | Guanylhydrazones and their use to treat inflammatory conditions |
EP0711553A1 (en) | 1994-08-09 | 1996-05-15 | Mario Cagnoni | Use of the Melatonin in the traetment of the articular symptoms of trheumatoid arthritis |
US5559135A (en) * | 1994-09-14 | 1996-09-24 | Merck & Co., Inc. | Endothelin antagonists bearing pyridyl amides |
WO1996018607A1 (fr) * | 1994-12-12 | 1996-06-20 | Chugai Seiyaku Kabushiki Kaisha | Derive d'aniline inhibant la synthase du monoxyde d'azote |
US5602277A (en) | 1995-03-30 | 1997-02-11 | Biocryst Pharmaceuticals, Inc. | Substituted benzene derivatives useful as neuraminidase inhibitors |
US5958934A (en) | 1996-05-23 | 1999-09-28 | Syntex (U.S.A.) Inc. | Aryl pyrimidine derivatives and uses thereof |
SE9604348D0 (sv) * | 1996-11-26 | 1996-11-26 | Wapharm Ab | Användning av hydroxyguanidiner |
AU7464998A (en) | 1997-10-27 | 1999-05-17 | Trega Biosciences, Inc. | Melanocortin receptor ligands and methods of using same |
WO1999052936A2 (en) | 1998-04-09 | 1999-10-21 | Eisai Co., Ltd. | Arginine peptide analogs useful as fibroblast growth factor antagonists |
US6127381A (en) | 1998-04-28 | 2000-10-03 | Basu; Amaresh | Isoquinoline compound melanocortin receptor ligands and methods of using same |
AU742425B2 (en) | 1998-06-11 | 2002-01-03 | Merck & Co., Inc. | Spiropiperidine derivatives as melanocortin receptor agonists |
WO2000009115A1 (en) | 1998-08-14 | 2000-02-24 | Smithkline Beecham Corporation | Grp receptor ligands |
GB9827500D0 (en) | 1998-12-14 | 1999-02-10 | Wapharm Ab | Compounds for control of eating, growth and body weight |
US6544541B1 (en) | 1999-06-02 | 2003-04-08 | Cardiovascular Solutions, Inc. | Devices and compounds for treating arterial restenosis |
AU6605800A (en) | 1999-07-16 | 2001-02-05 | Trega Biosciences, Inc. | Melanocortin receptor-3 ligands to treat sexual dysfunction |
AU6528400A (en) | 1999-08-23 | 2001-03-19 | David M. Ockert | Triple drug therapy for the treatment of narcotic and alcohol withdrawal symptoms |
AU7802700A (en) * | 1999-10-06 | 2001-05-10 | Melacure Therapeutics Ab | Guanidine derivatives and their use in the production of a medicament for blocking xanthine oxidase/dehydrogenase |
GB0019357D0 (en) * | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel phenyl guanidines |
GB0019359D0 (en) | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel guanidines |
GB0108631D0 (en) | 2001-04-05 | 2001-05-30 | Melacure Therapeutics Ab | Novel benzylideneamino guanidines and their uses as ligands to the melanocortin receptors |
GB0119172D0 (en) * | 2001-08-06 | 2001-09-26 | Melacure Therapeutics Ab | Phenyl pyrrole derivatives |
US7060711B2 (en) | 2001-10-25 | 2006-06-13 | Biofrontera Bioscience Gmbh | Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-HT2B receptor antagonist |
GB0622826D0 (en) * | 2006-11-15 | 2006-12-27 | Acurepharma Ab | Novel amides acting on the adenosine receptors |
GB0624987D0 (en) * | 2006-12-14 | 2007-01-24 | Acure Pharma Ab | Novel aminoguanidines as melanocortin receptor ligands |
-
2000
- 2000-08-07 GB GB0019357A patent/GB0019357D0/en not_active Ceased
-
2001
- 2001-08-07 BR BR0113053A patent/BR0113053A/pt not_active Application Discontinuation
- 2001-08-07 IL IL15427201A patent/IL154272A0/xx unknown
- 2001-08-07 MX MXPA03001072A patent/MXPA03001072A/es active IP Right Grant
- 2001-08-07 WO PCT/GB2001/003534 patent/WO2002011715A2/en not_active Application Discontinuation
- 2001-08-07 AU AU2001276522A patent/AU2001276522A1/en not_active Abandoned
- 2001-08-07 US US10/343,325 patent/US20040024060A1/en not_active Abandoned
- 2001-08-07 JP JP2002517052A patent/JP5654190B2/ja not_active Expired - Fee Related
- 2001-08-07 EP EP20010954176 patent/EP1313461A2/en not_active Withdrawn
- 2001-08-07 KR KR20037001846A patent/KR100929363B1/ko not_active IP Right Cessation
- 2001-08-07 CA CA 2417098 patent/CA2417098A1/en not_active Abandoned
-
2003
- 2003-01-30 ZA ZA200300829A patent/ZA200300829B/xx unknown
- 2003-02-03 IL IL15427203A patent/IL154272A/en not_active IP Right Cessation
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2006
- 2006-12-15 US US11/639,190 patent/US8148429B2/en not_active Expired - Fee Related
-
2007
- 2007-05-16 US US11/798,669 patent/US20070231267A1/en not_active Abandoned
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2010
- 2010-09-28 US US12/892,402 patent/US8309609B2/en not_active Expired - Fee Related
-
2011
- 2011-07-04 JP JP2011148414A patent/JP5683396B2/ja not_active Expired - Fee Related
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2012
- 2012-03-21 US US13/426,096 patent/US8410174B2/en not_active Expired - Fee Related
-
2013
- 2013-03-14 US US13/803,555 patent/US9227927B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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WO2002011715A3 (en) | 2003-01-16 |
WO2002011715A2 (en) | 2002-02-14 |
JP5683396B2 (ja) | 2015-03-11 |
CA2417098A1 (en) | 2002-02-14 |
JP2004505912A (ja) | 2004-02-26 |
US8410174B2 (en) | 2013-04-02 |
US20040024060A1 (en) | 2004-02-05 |
US20110015437A1 (en) | 2011-01-20 |
US8148429B2 (en) | 2012-04-03 |
KR100929363B1 (ko) | 2009-12-02 |
JP2011246471A (ja) | 2011-12-08 |
US20130295009A1 (en) | 2013-11-07 |
EP1313461A2 (en) | 2003-05-28 |
US20120178820A1 (en) | 2012-07-12 |
BR0113053A (pt) | 2003-07-08 |
US8309609B2 (en) | 2012-11-13 |
KR20030022371A (ko) | 2003-03-15 |
IL154272A0 (en) | 2003-09-17 |
IL154272A (en) | 2010-12-30 |
ZA200300829B (en) | 2004-02-25 |
US20070231267A1 (en) | 2007-10-04 |
JP5654190B2 (ja) | 2015-01-14 |
MXPA03001072A (es) | 2004-03-10 |
US20070088085A1 (en) | 2007-04-19 |
US9227927B2 (en) | 2016-01-05 |
GB0019357D0 (en) | 2000-09-27 |
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