ATE98640T1 - Substituierte 1h-imidazole. - Google Patents
Substituierte 1h-imidazole.Info
- Publication number
- ATE98640T1 ATE98640T1 AT87870149T AT87870149T ATE98640T1 AT E98640 T1 ATE98640 T1 AT E98640T1 AT 87870149 T AT87870149 T AT 87870149T AT 87870149 T AT87870149 T AT 87870149T AT E98640 T1 ATE98640 T1 AT E98640T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- hydrogen
- compounds
- methyl
- imidazole
- Prior art date
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical class C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 imidazole compound Chemical class 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000002253 anti-ischaemic effect Effects 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Resins (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868626287A GB8626287D0 (en) | 1986-11-04 | 1986-11-04 | Substituted 1h-imidazoles |
| EP87870149A EP0269599B1 (de) | 1986-11-04 | 1987-10-30 | Substituierte 1H-Imidazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE98640T1 true ATE98640T1 (de) | 1994-01-15 |
Family
ID=10606751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87870149T ATE98640T1 (de) | 1986-11-04 | 1987-10-30 | Substituierte 1h-imidazole. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4814343A (de) |
| EP (1) | EP0269599B1 (de) |
| JP (1) | JP2632877B2 (de) |
| KR (1) | KR910003116B1 (de) |
| AT (1) | ATE98640T1 (de) |
| AU (1) | AU592733B2 (de) |
| CA (1) | CA1301174C (de) |
| CY (1) | CY1845A (de) |
| DE (1) | DE3788507T2 (de) |
| DK (1) | DK166584B1 (de) |
| ES (1) | ES2060608T3 (de) |
| FI (1) | FI91858C (de) |
| GB (1) | GB8626287D0 (de) |
| HK (1) | HK78895A (de) |
| HU (1) | HU206684B (de) |
| IE (1) | IE61901B1 (de) |
| IL (1) | IL84322A (de) |
| MY (1) | MY102578A (de) |
| NO (1) | NO169960C (de) |
| NZ (1) | NZ222382A (de) |
| PL (3) | PL156482B1 (de) |
| PT (1) | PT86040B (de) |
| SU (4) | SU1662349A3 (de) |
| ZA (1) | ZA878170B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0336759A1 (de) * | 1988-04-07 | 1989-10-11 | Glaxo Group Limited | Imidazol-Derivate |
| GB8810067D0 (en) * | 1988-04-28 | 1988-06-02 | Ucb Sa | Substituted 1-(1h-imidazol-4-yl)alkyl-benzamides |
| JPH04252867A (ja) * | 1991-01-25 | 1992-09-08 | Nissan Motor Co Ltd | 内燃機関の燃料供給装置 |
| GB9310965D0 (en) * | 1993-05-27 | 1993-07-14 | Ucb Sa | 2-hydroxy-3-(1h-imidazol-4-yl)alkyl)benzenecarboximidamides |
| WO1995014007A1 (en) * | 1993-11-15 | 1995-05-26 | Schering Corporation | Phenyl-alkyl imidazoles as h3-receptor antagonists |
| GB9425211D0 (en) * | 1994-12-14 | 1995-02-15 | Ucb Sa | Substituted 1H-imidazoles |
| GB9521680D0 (en) * | 1995-10-23 | 1996-01-03 | Orion Yhtymo Oy | New use of imidazole derivatives |
| US7868020B2 (en) * | 2007-01-12 | 2011-01-11 | Allergan, Inc. | Quinolynylmethylimidizoles as therapeutic agents |
| WO2008088937A1 (en) * | 2007-01-12 | 2008-07-24 | Allergan, Inc. | Quinolynylmethylimidizoles as therapeutic agents |
| US8013169B2 (en) * | 2007-01-12 | 2011-09-06 | Allergan, Inc | Naphthylmethylimidizoles as therapeutic agents |
| RU2373934C1 (ru) * | 2008-03-19 | 2009-11-27 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Применение производных глутаровой кислоты или их фармацевтически приемлемых солей в качестве противоаритмических средств |
| WO2024260319A1 (zh) * | 2023-06-19 | 2024-12-26 | 江苏恩华药业股份有限公司 | 一种取代咪唑衍生物、中间体、制备方法及其应用 |
| CN120865095A (zh) * | 2025-07-04 | 2025-10-31 | 武穴宏源药业有限公司 | 一种咪唑环合液的提纯方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US29761A (en) * | 1860-08-28 | Improvements in telegraphic apparatus | ||
| US4070472A (en) | 1974-02-07 | 1978-01-24 | Smith Kline & French Laboratories Limited | Guanidino, thioureido, isothioureido and nitrovinylamino derivatives of pyridine |
| AU518569B2 (en) * | 1979-08-07 | 1981-10-08 | Farmos-Yhtyma Oy | 4-benzyl- and 4-benzoyl imidazole derivatives |
| GB2092569B (en) * | 1981-02-05 | 1984-09-19 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
| GB2101114B (en) * | 1981-07-10 | 1985-05-22 | Farmos Group Ltd | Substituted imidazole derivatives and their preparation and use |
| DE4224020A1 (de) * | 1992-07-22 | 1994-01-27 | Deutsche Aerospace | Verfahren zur Auslösung der Zündung eines Gefechtskopfes und Anordnung zum Durchführen des Verfahrens |
-
1986
- 1986-11-04 GB GB868626287A patent/GB8626287D0/en active Pending
-
1987
- 1987-10-14 CA CA000549258A patent/CA1301174C/en not_active Expired - Lifetime
- 1987-10-30 NZ NZ222382A patent/NZ222382A/en unknown
- 1987-10-30 AT AT87870149T patent/ATE98640T1/de not_active IP Right Cessation
- 1987-10-30 ES ES87870149T patent/ES2060608T3/es not_active Expired - Lifetime
- 1987-10-30 IL IL84322A patent/IL84322A/xx not_active IP Right Cessation
- 1987-10-30 FI FI874789A patent/FI91858C/fi not_active IP Right Cessation
- 1987-10-30 PT PT86040A patent/PT86040B/pt not_active IP Right Cessation
- 1987-10-30 ZA ZA878170A patent/ZA878170B/xx unknown
- 1987-10-30 EP EP87870149A patent/EP0269599B1/de not_active Expired - Lifetime
- 1987-10-30 DE DE3788507T patent/DE3788507T2/de not_active Expired - Fee Related
- 1987-10-31 KR KR1019870012264A patent/KR910003116B1/ko not_active Expired
- 1987-11-02 PL PL1987288654A patent/PL156482B1/pl unknown
- 1987-11-02 AU AU80593/87A patent/AU592733B2/en not_active Ceased
- 1987-11-02 DK DK572987A patent/DK166584B1/da active
- 1987-11-02 PL PL1987288655A patent/PL156483B1/pl unknown
- 1987-11-02 MY MYPI87003010A patent/MY102578A/en unknown
- 1987-11-02 PL PL1987268558A patent/PL155119B1/pl unknown
- 1987-11-02 JP JP62278144A patent/JP2632877B2/ja not_active Expired - Lifetime
- 1987-11-02 US US07/116,325 patent/US4814343A/en not_active Expired - Lifetime
- 1987-11-03 SU SU874203647A patent/SU1662349A3/ru active
- 1987-11-03 IE IE296387A patent/IE61901B1/en not_active IP Right Cessation
- 1987-11-03 NO NO874572A patent/NO169960C/no not_active IP Right Cessation
- 1987-11-04 HU HU874948A patent/HU206684B/hu not_active IP Right Cessation
-
1988
- 1988-06-30 SU SU884356015A patent/SU1710558A1/ru active
- 1988-12-22 SU SU884613108A patent/SU1635899A3/ru active
- 1988-12-22 SU SU884613197A patent/SU1628857A3/ru active
-
1995
- 1995-05-18 HK HK78895A patent/HK78895A/xx not_active IP Right Cessation
-
1996
- 1996-03-08 CY CY184596A patent/CY1845A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |