ATE554180T1 - Phenolische verbindungen mit kosmetischen und therapeutischen anwendungen - Google Patents

Phenolische verbindungen mit kosmetischen und therapeutischen anwendungen

Info

Publication number
ATE554180T1
ATE554180T1 AT07730118T AT07730118T ATE554180T1 AT E554180 T1 ATE554180 T1 AT E554180T1 AT 07730118 T AT07730118 T AT 07730118T AT 07730118 T AT07730118 T AT 07730118T AT E554180 T1 ATE554180 T1 AT E554180T1
Authority
AT
Austria
Prior art keywords
derivatives
acid
phenolics
cosmetic
culture
Prior art date
Application number
AT07730118T
Other languages
English (en)
Inventor
Daniel Auriol
Renaud Nalin
Patrick Robe
Fabrice Lefevre
Original Assignee
Libragen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Libragen filed Critical Libragen
Application granted granted Critical
Publication of ATE554180T1 publication Critical patent/ATE554180T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/075—Benzo[b]pyran-2-ones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT07730118T 2006-06-14 2007-06-13 Phenolische verbindungen mit kosmetischen und therapeutischen anwendungen ATE554180T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06290972A EP1867729A1 (de) 2006-06-14 2006-06-14 Wasserlösliche Phenolderivate mit hautkosmetischer und therapeutischer Verwendung
PCT/EP2007/055815 WO2007144368A2 (en) 2006-06-14 2007-06-13 Water soluble phenolics derivatives with dermocosmetic and therapeutic applications

Publications (1)

Publication Number Publication Date
ATE554180T1 true ATE554180T1 (de) 2012-05-15

Family

ID=37460272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07730118T ATE554180T1 (de) 2006-06-14 2007-06-13 Phenolische verbindungen mit kosmetischen und therapeutischen anwendungen

Country Status (11)

Country Link
US (3) US20090233876A1 (de)
EP (2) EP1867729A1 (de)
JP (1) JP5607925B2 (de)
KR (1) KR101165496B1 (de)
CN (2) CN105838758B (de)
AT (1) ATE554180T1 (de)
AU (1) AU2007260024A1 (de)
CA (1) CA2654480C (de)
ES (1) ES2384275T3 (de)
PL (1) PL2027279T3 (de)
WO (1) WO2007144368A2 (de)

Families Citing this family (58)

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EP2202237A1 (de) * 2008-12-23 2010-06-30 Libragen Wasserlösliche [6)-O-alpha-D-Glcp-(1->]n-6-O-beta-D-Glcp-(1->-Phenol-Derivate mit Dermokosmetik-, Ernährungs- und Therapieanwendungen und Zusammensetzungen mit den wasserlöslichen Verbindungen
KR101048355B1 (ko) * 2009-01-07 2011-07-14 전라남도 클로로제닉산 배당체의 제조방법
KR101048354B1 (ko) * 2009-01-07 2011-07-14 전라남도 카페익산 배당체의 제조방법
FR2958157B1 (fr) 2010-04-02 2012-06-29 Libragen Composition cosmetique et pharmaceutique comprenant du n-acetyl-glucosamine-6-phosphate
EP2612664A4 (de) * 2010-09-02 2014-03-19 Menicon Co Ltd Stabilisierte polyphenollösung und verfahren zur stabilisierung einer polyphenollösung
FR2964570A1 (fr) * 2010-09-09 2012-03-16 Burgundy Procede de preparation d'un extrait de centella asiatica
CN102174622B (zh) * 2011-01-17 2012-12-19 南京工业大学 一种S-α-D-葡萄糖苷-L-半胱氨酸的酶促合成方法
JP5783784B2 (ja) * 2011-04-25 2015-09-24 オリザ油化株式会社 一酸化窒素産生抑制剤
KR101432747B1 (ko) * 2012-05-23 2014-08-22 부산대학교 산학협력단 알파-치커린, 이를 포함하는 항암제 및 건강기능식품
US9072919B2 (en) 2012-10-12 2015-07-07 L'oreal S.A. Synergistic antioxidant cosmetic compositions containing at least one of baicalin and taxifolin, at least one of caffeine and nicotinamide, at least one of vitamin C and resveratrol and ferulic acid
US9023826B2 (en) 2012-10-12 2015-05-05 L'oreal S.A. Compositions containing adenosine and the hydrotropes caffeine and nicotinamide for cosmetic use
WO2014059228A1 (en) 2012-10-12 2014-04-17 L'oreal Cosmetic compositions containing at least one hydrotrope and at least one active compound
US9018177B2 (en) 2012-10-12 2015-04-28 L'oreal S.A. Cosmetic compositions for increasing bioavailability of the active compounds baicalin and/or vitamin C
US9107853B2 (en) 2012-10-12 2015-08-18 L'oreal S.A. Compositions containing phenolic compounds and hydrotropes for cosmetic use
CN103088078B (zh) * 2013-02-04 2015-07-01 江苏科技大学 咖啡酸丙酯的脂肪酶促合成方法
CN103304606B (zh) * 2013-06-25 2015-06-10 山东大学 咖啡酸糖苷衍生物及其制备方法
US9669242B2 (en) 2013-07-01 2017-06-06 L'oreal Compositions containing at least two phenolic compounds, a lipid-soluble antioxidant and at least one hydrotrope for cosmetic use
JP2015140307A (ja) * 2014-01-28 2015-08-03 一丸ファルコス株式会社 ロスマリン酸又はその配糖体を有効成分とするキネシン抑制剤
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CN104098624B (zh) * 2014-07-29 2016-04-13 新疆农业大学 一种结合型昆仑雪菊查耳酮糖苷化合物的制备及应用
WO2017073854A1 (ko) * 2015-10-30 2017-05-04 고려대학교산학협력단 단순 페놀릭 배당 유도체, 이의 제조방법 및 이를 함유하는 피부미백 또는 주름개선용 조성물
KR20210094657A (ko) 2016-01-15 2021-07-29 함부르크대학교 람노실화된 플라보노이드의 제조 방법
CA3011192A1 (en) 2016-01-15 2017-07-20 Universitat Hamburg Flavonoide-type compounds bearing an o-rhamnosyl residue
CN108853085A (zh) * 2017-05-15 2018-11-23 苏州凯祥生物科技有限公司 儿茶素类和表儿茶素类化合物用于上调MicroRNA-126表达水平的用途
CN108853086A (zh) * 2017-05-15 2018-11-23 苏州凯祥生物科技有限公司 儿茶素类和表儿茶素类化合物用于上调MicroRNA-150表达水平的用途
JP7174757B2 (ja) 2017-07-04 2022-11-17 イントゥーセル，インコーポレーティッド 切断可能なリンカーを含む化合物及びその使用
CN108409509B (zh) * 2017-11-08 2020-12-18 江西省农业科学院土壤肥料与资源环境研究所 农业组合物及其制备方法
EP3488849A1 (de) 2017-11-23 2019-05-29 Assistance Publique, Hopitaux De Paris Epigallocathechingallatlösung
CN107858335B (zh) * 2017-12-25 2021-07-16 南京华狮新材料有限公司 蔗糖磷酸化酶突变体及其在生产甘油葡萄糖苷中应用
US10897045B2 (en) * 2018-04-11 2021-01-19 Ut-Battelle, Llc Crosslinked functional binders and their use in silicon-containing anodes of lithium-ion batteries
CN108997459B (zh) * 2018-06-22 2022-06-21 陕西帕尼尔生物科技有限公司 一种具有抗氧化活性的秦皮甲素硫代二丙酸酯化合物及其合成方法
KR102128454B1 (ko) * 2018-09-20 2020-07-01 한국한의학연구원 마크루린을 포함하는 피부 미백용 조성물
KR102110363B1 (ko) * 2018-10-26 2020-05-15 한국한의학연구원 마크루린을 유효성분으로 포함하는 식품 갈변 방지용 조성물
GB201817625D0 (en) 2018-10-29 2018-12-12 Givaudan Sa Hair care active agent
CN109481433A (zh) * 2019-01-03 2019-03-19 南京中医药大学 Dehydrophyllodulcin在制备抗肿瘤转移药物中的应用
ES2912262T3 (es) 2019-05-29 2022-05-25 Hopitaux Paris Assist Publique Sistema eutéctico de las catequinas del té verde
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CN110981925B (zh) * 2019-11-18 2021-05-25 福州百草堂医药科技有限公司 二氢燕麦生物碱d葡萄糖苷或其盐类化合物及其在化妆品中的应用
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BR112022021012A2 (pt) * 2020-04-17 2023-02-28 Conagen Inc Bloqueadores de sabor amargo e métodos de uso relacionados
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CN114674958B (zh) * 2022-03-25 2023-06-06 天津中医药大学 一种大皂角中活性成分含量的测定方法
KR20240023004A (ko) * 2022-08-12 2024-02-20 포항공과대학교 산학협력단 고시페틴을 포함하는 지방간 개선용 조성물
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CN116549469B (zh) * 2023-02-27 2024-09-13 中国科学院新疆理化技术研究所 一种黄酮类化合物槲皮素-3-O-(6”-咖啡酰基)-β-D-葡萄糖苷的用途
KR102789411B1 (ko) * 2023-12-14 2025-04-01 국립부경대학교 산학협력단 류코노스톡 메센테로이데스 신규 분리주 및 이의 용도
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