ATE548464T1 - Detektion von nukleinsäuren durch typenspezifische hybrid-capture methode - Google Patents
Detektion von nukleinsäuren durch typenspezifische hybrid-capture methodeInfo
- Publication number
- ATE548464T1 ATE548464T1 AT01944578T AT01944578T ATE548464T1 AT E548464 T1 ATE548464 T1 AT E548464T1 AT 01944578 T AT01944578 T AT 01944578T AT 01944578 T AT01944578 T AT 01944578T AT E548464 T1 ATE548464 T1 AT E548464T1
- Authority
- AT
- Austria
- Prior art keywords
- detection
- type
- specific hybrid
- nucleic acids
- capture method
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6832—Enhancement of hybridisation reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/708—Specific hybridization probes for papilloma
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/594,839 US7439016B1 (en) | 2000-06-15 | 2000-06-15 | Detection of nucleic acids by type-specific hybrid capture method |
| PCT/US2001/019353 WO2001096608A1 (en) | 2000-06-15 | 2001-06-15 | Detection of nucleic acids by type-specific hybrid capture method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE548464T1 true ATE548464T1 (de) | 2012-03-15 |
Family
ID=24380618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01944578T ATE548464T1 (de) | 2000-06-15 | 2001-06-15 | Detektion von nukleinsäuren durch typenspezifische hybrid-capture methode |
Country Status (12)
| Country | Link |
|---|---|
| US (6) | US7439016B1 (de) |
| EP (3) | EP2308997B1 (de) |
| JP (2) | JP5166666B2 (de) |
| AT (1) | ATE548464T1 (de) |
| AU (2) | AU6697401A (de) |
| BR (1) | BR0111992B1 (de) |
| CA (2) | CA2796223A1 (de) |
| DK (1) | DK1967594T3 (de) |
| ES (1) | ES2545183T3 (de) |
| PT (1) | PT1967594E (de) |
| SI (1) | SI1967594T1 (de) |
| WO (1) | WO2001096608A1 (de) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6355424B1 (en) * | 1997-12-12 | 2002-03-12 | Digene Corporation | Assessment of human papillomavirus-related disease |
| EP2295968B1 (de) * | 1999-12-03 | 2012-09-19 | Baxter International Inc. | Test für Pyrogenizität zum Gebrauch in Verbindung mit automatisierten Immunoassay-Systemen |
| US7601497B2 (en) * | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| US7439016B1 (en) * | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| GB0200258D0 (en) * | 2002-01-07 | 2002-02-20 | Norchip As | Detection of human papillomavirus |
| NZ533703A (en) * | 2002-01-07 | 2006-05-26 | Norchip As | Method for detecting human papillomavirus mRNA |
| WO2003083440A2 (en) * | 2002-03-29 | 2003-10-09 | Genentech, Inc. | Methods and compositions for detection and quantitation of nucleic acid analytes |
| ES2463420T3 (es) * | 2002-11-01 | 2014-05-27 | Iris International, Inc. | Inmuno-PCR sándwich por desplazamiento |
| US7597936B2 (en) * | 2002-11-26 | 2009-10-06 | University Of Utah Research Foundation | Method of producing a pigmented composite microporous material |
| US8575327B2 (en) | 2003-06-12 | 2013-11-05 | Alnylam Pharmaceuticals, Inc. | Conserved HBV and HCV sequences useful for gene silencing |
| JP4980716B2 (ja) * | 2003-06-12 | 2012-07-18 | アルナイラム ファーマシューティカルズ， インコーポレイテッド | 遺伝子サイレンシングに有用な保存されたｈｂｖ及びｈｃｖ配列 |
| AU2004286235B2 (en) | 2003-10-21 | 2011-05-12 | Orion Genomics Llc | Differential enzymatic fragmentation |
| GB0404315D0 (en) * | 2004-02-26 | 2004-03-31 | Norchip As | Improved detection of human papillomavirus |
| WO2006137933A2 (en) | 2004-11-03 | 2006-12-28 | Leucadia Technologies, Inc. | Microbubbles for affinity separation |
| PT1842226E (pt) | 2004-11-03 | 2010-11-29 | Iris Molecular Diagnostics Inc | Detecção homogénea de analitos |
| ATE476528T1 (de) | 2004-12-08 | 2010-08-15 | Gen Probe Inc | Nukleinsäuredetektion aus verschiedenen typen des humanen papillomavirus |
| EP1997914A1 (de) * | 2007-06-01 | 2008-12-03 | Università Degli Studi Di Milano - Bicocca | Identifizierung und Quantifizierung onkogener HPV-Nukleinsäuren mittels PCR-Assays in Echtzeit |
| TWI419974B (zh) | 2008-10-27 | 2013-12-21 | Qiagen Gaithersburg Inc | 於自動平台上之快速結果雜交捕捉法 |
| AU2009313808B2 (en) * | 2008-11-14 | 2013-05-16 | Gen-Probe Incorporated | Compositions, kits and methods for detection of campylobacter nucleic acid |
| EP2373817A4 (de) * | 2008-12-10 | 2013-01-02 | Illumina Inc | Verfahren und zusammensetzungen zur hybridisierung von nukleinsäuren |
| CA2750338C (en) * | 2009-01-28 | 2019-06-25 | Qiagen Gaithersburg, Inc. | Sequence-specific large volume sample preparation method and assay |
| JP5738278B2 (ja) * | 2009-05-01 | 2015-06-24 | キアジェン ゲイサーズバーグ インコーポレイテッド | 試料中のｒｎａスプライシング形態を検出するための非標的増幅法 |
| AU2010291990B2 (en) * | 2009-09-14 | 2016-05-05 | Qiagen Gaithersburg, Inc. | Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media |
| JP5876834B2 (ja) * | 2010-01-04 | 2016-03-02 | キアジェン ゲイサーズバーグ インコーポレイテッド | 固定された組織サンプルからの核酸またはタンパク質の回収のための方法、組成物、およびキット |
| US20120021460A1 (en) | 2010-01-08 | 2012-01-26 | Qiagen Gaithersburg Inc. | Materials and methods for isothermal nucleic acid amplification |
| AU2011210734B2 (en) * | 2010-01-29 | 2017-02-09 | Qiagen Gaithersburg, Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| BR112012018545A2 (pt) * | 2010-01-29 | 2016-05-03 | Qiagen Gaithersburg Inc | método de determinação e confirmação da presença de um hpv em uma amostra |
| WO2011106583A1 (en) * | 2010-02-26 | 2011-09-01 | Ventana Medical Systems, Inc. | Polytag probes |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| WO2011146629A2 (en) * | 2010-05-19 | 2011-11-24 | Qiagen Gaithersburg Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| AU2011258501B2 (en) | 2010-05-25 | 2016-07-07 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically-truncated probes |
| CN103429755A (zh) | 2010-10-21 | 2013-12-04 | 领先细胞医疗诊断有限公司 | 用于原位检测核酸的超灵敏方法 |
| CN103517994A (zh) | 2011-01-07 | 2014-01-15 | 奇亚根盖瑟斯堡股份有限公司 | 用于对高风险人乳头瘤病毒进行基因型分型和定量的材料和方法 |
| US9885092B2 (en) * | 2011-02-24 | 2018-02-06 | Qiagen Gaithersburg Inc. | Materials and methods for detection of HPV nucleic acids |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| JP6103778B2 (ja) | 2011-11-03 | 2017-03-29 | キアジェン ゲイサーズバーグ インコーポレイテッド | カルボキシル化表面を使用して細胞を固定、単離、および濃縮するための材料および方法 |
| CN102492660B (zh) * | 2011-11-28 | 2013-12-11 | 浙江大学 | 乙型肝炎病毒突变体、突变扩增试剂盒及应用 |
| US9868979B2 (en) | 2013-06-25 | 2018-01-16 | Prognosys Biosciences, Inc. | Spatially encoded biological assays using a microfluidic device |
| JP6644297B2 (ja) | 2013-09-26 | 2020-02-12 | 東洋鋼鈑株式会社 | ハイブリダイゼーション用バッファー組成物及びハイブリダイゼーション方法 |
| WO2015095840A1 (en) | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of cdk and erk inhibitors |
| CA3168002A1 (en) | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Cancer treatment using combinations of erk and raf inhibitors |
| JP6678583B2 (ja) | 2013-12-20 | 2020-04-22 | バイオメッド バレー ディスカバリーズ，インコーポレイティド | ２型ｍｅｋ阻害剤およびｅｒｋ阻害剤の組み合わせを用いるがん処置 |
| ES2918375T3 (es) | 2013-12-20 | 2022-07-15 | Biomed Valley Discoveries Inc | Tratamientos contra el cáncer usando combinaciones de inhibidores de la ruta de PI3K/Akt y ERK |
| JOP20200092A1 (ar) | 2014-11-10 | 2017-06-16 | Alnylam Pharmaceuticals Inc | تركيبات iRNA لفيروس الكبد B (HBV) وطرق لاستخدامها |
| ES2955916T3 (es) | 2015-04-10 | 2023-12-11 | Spatial Transcriptomics Ab | Análisis múltiplex de especímenes biológicos de ácidos nucleicos espacialmente distinguidos |
| US20200087726A1 (en) * | 2015-05-10 | 2020-03-19 | Quandx Inc. | Ultra sensitive probes for detection of nucleic acid |
| WO2016183042A1 (en) * | 2015-05-10 | 2016-11-17 | Quandx Inc. | Ultra sensitive probes for detection of nucleic acid |
| US11078528B2 (en) | 2015-10-12 | 2021-08-03 | Advanced Cell Diagnostics, Inc. | In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto |
| JP6757942B2 (ja) | 2016-08-03 | 2020-09-23 | 東洋鋼鈑株式会社 | ハイブリダイゼーション用バッファー組成物及びハイブリダイゼーション方法 |
| US11324820B2 (en) | 2017-04-18 | 2022-05-10 | Alnylam Pharmaceuticals, Inc. | Methods for the treatment of subjects having a hepatitis b virus (HBV) infection |
| MX2021001056A (es) | 2018-08-13 | 2021-04-12 | Alnylam Pharmaceuticals Inc | Composiciones de agente de acido ribonucleico bicatenario (arnbc) de virus de la hepatitis b (vhb) y metodos de uso de las mismas. |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| EP3894592A2 (de) | 2018-12-10 | 2021-10-20 | 10X Genomics, Inc. | Erzeugung von räumlichen anordnungen mit gradienten |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| EP3976820A1 (de) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Verfahren zum nachweis der räumlichen heterogenität einer biologischen probe |
| EP4025711A2 (de) | 2019-11-08 | 2022-07-13 | 10X Genomics, Inc. | Erhöhung der spezifität einer analytbindung |
| EP3891300B1 (de) | 2019-12-23 | 2023-03-29 | 10X Genomics, Inc. | Verfahren zur räumlichen analyse mittels rna-template-ligation |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| ES2965354T3 (es) | 2020-04-22 | 2024-04-12 | 10X Genomics Inc | Métodos para análisis espacial que usan eliminación de ARN elegido como diana |
| US20230242971A1 (en) * | 2020-05-08 | 2023-08-03 | Roche Sequencing Solutions, Inc. | Removal of excess oligonucleotides from a reation mixture |
| AU2021275906A1 (en) | 2020-05-22 | 2022-12-22 | 10X Genomics, Inc. | Spatial analysis to detect sequence variants |
| WO2021236929A1 (en) | 2020-05-22 | 2021-11-25 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
| WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
| EP4162074B1 (de) | 2020-06-08 | 2024-04-24 | 10X Genomics, Inc. | Verfahren zur bestimmung eines chirurgischen randes und verfahren zur verwendung davon |
| EP4165207A1 (de) | 2020-06-10 | 2023-04-19 | 10X Genomics, Inc. | Verfahren zur bestimmung einer position eines analyten in einer biologischen probe |
| WO2021252576A1 (en) * | 2020-06-10 | 2021-12-16 | 10X Genomics, Inc. | Methods for spatial analysis using blocker oligonucleotides |
| CN116034166A (zh) | 2020-06-25 | 2023-04-28 | 10X基因组学有限公司 | Dna甲基化的空间分析 |
| US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| AU2021409136A1 (en) | 2020-12-21 | 2023-06-29 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| CN113215163B (zh) * | 2021-05-12 | 2023-05-12 | 苏州海苗生物科技有限公司 | 一种特异性扩增目的基因的分子锁及应用 |
| WO2023034489A1 (en) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
Family Cites Families (145)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US792585A (en) | 1904-11-11 | 1905-06-20 | Jonas F Dixon | Apparatus for fastening bed-springs to wire bases. |
| US4732847A (en) | 1981-06-09 | 1988-03-22 | University Of Hawaii | Monoclonal antibodies for DNA-RNA hybrid complexes and their uses |
| FI63596C (fi) | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
| US4486536A (en) | 1982-05-28 | 1984-12-04 | Smithkline Diagnostics, Inc. | Specimen slide for occult blood testing |
| US4865980A (en) | 1982-12-29 | 1989-09-12 | University Of Hawaii | Monoclonal antibodies for DNA-RNA hybrid complexes and their uses |
| US5288611A (en) | 1983-01-10 | 1994-02-22 | Gen-Probe Incorporated | Method for detecting, identifying, and quantitating organisms and viruses |
| JPS60501339A (ja) | 1983-01-10 | 1985-08-22 | ジエン−プロ−ブ インコ−ポレィテッド | 生物を検出、同定又は定量する方法およびキット |
| US5200313A (en) | 1983-08-05 | 1993-04-06 | Miles Inc. | Nucleic acid hybridization assay employing detectable anti-hybrid antibodies |
| EP0144914A3 (de) | 1983-12-12 | 1986-08-13 | Miles Inc. | Hybridisierungstest mittels markierter Paare von hybridbindenden Reagenzien |
| US4743535A (en) | 1984-11-07 | 1988-05-10 | Miles Inc. | Hybridization assay employing labeled probe and anti-hybrid |
| AU3844485A (en) | 1984-02-09 | 1985-08-15 | Enzo Biochem Inc. | Heterologous detection of cabeled dna |
| FI71768C (fi) | 1984-02-17 | 1987-02-09 | Orion Yhtymae Oy | Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning. |
| US6221581B1 (en) * | 1984-04-27 | 2001-04-24 | Enzo Diagnostics, Inc. | Processes for detecting polynucleotides, determining genetic mutations or defects in genetic material, separating or isolating nucleic acid of interest from samples, and useful compositions of matter and multihybrid complex compositions |
| CA1260372A (en) | 1984-04-27 | 1989-09-26 | Elazar Rabbani | Hybridization method for the detection of genetic materials |
| CA1253777A (en) | 1984-06-01 | 1989-05-09 | Robert J. Carrico | Nucleic acid hybridization assay employing immobilized rna probes |
| ZA853756B (en) | 1984-06-01 | 1986-01-29 | Miles Lab | Nucleic acid hybridization assay employing immobilized rna probes |
| IL75648A0 (en) | 1984-07-05 | 1985-10-31 | Gen Probe Inc | Accelerated nucleic acid reassociation method |
| US4563417A (en) | 1984-08-31 | 1986-01-07 | Miles Laboratories, Inc. | Nucleic acid hybridization assay employing antibodies to intercalation complexes |
| US4775619A (en) | 1984-10-16 | 1988-10-04 | Chiron Corporation | Polynucleotide determination with selectable cleavage sites |
| US4689294A (en) | 1984-11-19 | 1987-08-25 | Miles Laboratories, Inc. | Enhancement of hybridization of nucleic acids by anionic polymers |
| US5641630A (en) * | 1985-06-13 | 1997-06-24 | Amgen Inc. | Method and kit for performing nucleic acid hybridization assays |
| US4751177A (en) | 1985-06-13 | 1988-06-14 | Amgen | Methods and kits for performing nucleic acid hybridization assays |
| ES8707343A1 (es) * | 1985-06-13 | 1987-07-16 | Amgen | Un metodo para aislar una secuencia de acido nucleico objetivo seleccionada |
| US4868105A (en) | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| US5750338A (en) * | 1986-10-23 | 1998-05-12 | Amoco Corporation | Target and background capture methods with amplification for affinity assays |
| EP0272009B2 (de) | 1986-11-24 | 2007-10-03 | Gen-Probe Incorporated | Nukleinsäuresonden zum Nachweis und/oder zur Quantifizierung von nicht-viralen Organismen |
| AU601021B2 (en) | 1987-03-11 | 1990-08-30 | Molecular Diagnostics, Inc. | Assay for necleic acid sequences in a sample |
| IL85551A0 (en) | 1987-04-01 | 1988-08-31 | Miles Inc | Rapid hybridization assay and reagent system used therein |
| GB8717169D0 (en) * | 1987-07-21 | 1987-08-26 | Ti Interlock Ltd | Pneumatic control system |
| US5359100A (en) | 1987-10-15 | 1994-10-25 | Chiron Corporation | Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers |
| US5656731A (en) | 1987-10-15 | 1997-08-12 | Chiron Corporation | Nucleic acid-amplified immunoassay probes |
| DE3854943T2 (de) * | 1987-12-01 | 1996-09-05 | Amoco Corp | Nachweis von salmonella |
| US5082830A (en) * | 1988-02-26 | 1992-01-21 | Enzo Biochem, Inc. | End labeled nucleotide probe |
| ATE108491T1 (de) * | 1988-03-18 | 1994-07-15 | Baylor College Medicine | Mutationsnachweis durch kompetitiven oligonukleotid-priming. |
| US6326136B1 (en) | 1988-04-01 | 2001-12-04 | Digene Corporation | Macromolecular conjugate made using unsaturated aldehydes |
| US5374524A (en) | 1988-05-10 | 1994-12-20 | E. I. Du Pont De Nemours And Company | Solution sandwich hybridization, capture and detection of amplified nucleic acids |
| NO165894C (no) | 1988-05-24 | 1991-04-24 | Gunnar Paulsen | Analysemetode for gener. |
| WO1990001563A1 (en) * | 1988-08-01 | 1990-02-22 | Cimino George D | Identification of allele specific nucleic acid sequences by hybridization with crosslinkable oligonucleotide probes |
| DE3856224T2 (de) | 1988-09-29 | 1998-12-03 | Chiron Corp., Emeryville, Calif. | Nachweis eines Polynukleotids durch Ersätzung einer Kette an einer Fangsonde |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| ATE118824T1 (de) * | 1989-03-10 | 1995-03-15 | Amoco Corp | Immobilisierte oligonukleotidsonden und ihre verwendungen. |
| US5106727A (en) * | 1989-04-27 | 1992-04-21 | Life Technologies, Inc. | Amplification of nucleic acid sequences using oligonucleotides of random sequences as primers |
| DE69032847T2 (de) | 1989-06-30 | 1999-05-12 | Chiron Corp | Hydrophobe Nukleinsäure-Sonde |
| US5116734A (en) | 1989-09-01 | 1992-05-26 | Digene Diagnostics, Inc. | Highly sensitive method for detecting peroxidase |
| CA2028012A1 (en) * | 1989-10-23 | 1991-04-24 | Randall Dimond | Hybridization assay for campylobacter rrna |
| JPH05501650A (ja) | 1989-12-01 | 1993-04-02 | バイシス・インコーポレーテツド | Ｈｐｖ転写物の検出 |
| US5580970A (en) * | 1989-12-01 | 1996-12-03 | Amoco Corporation | Detection of HPV transcripts |
| US5629153A (en) | 1990-01-10 | 1997-05-13 | Chiron Corporation | Use of DNA-dependent RNA polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays |
| US5792606A (en) | 1990-02-26 | 1998-08-11 | Boehringer Mannheim Gmbh | Nucleic acid hybridization based assay for determining a substance of interest |
| CA2039517C (en) | 1990-04-03 | 2006-11-07 | David Segev | Dna probe signal amplification |
| US5695926A (en) | 1990-06-11 | 1997-12-09 | Bio Merieux | Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophobic support |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5484699A (en) | 1990-09-28 | 1996-01-16 | Abbott Laboratories | Nucleotide sequences useful as type specific probes, PCR primers and LCR probes for the amplification and detection of human papilloma virus, and related kits and methods |
| EP0557456A4 (en) | 1990-11-14 | 1995-11-15 | Siska Diagnostics Inc | Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor |
| US5283175A (en) * | 1991-04-15 | 1994-02-01 | The Research Foundation Of State University Of New York | Genus-specific oligomers of Borrelia and methods of using same |
| US5556748A (en) | 1991-07-30 | 1996-09-17 | Xenopore Corporation | Methods of sandwich hybridization for the quantitative analysis of oligonucleotides |
| ES2145750T3 (es) | 1991-11-14 | 2000-07-16 | Dgi Inc | Kit y dosificado que utiliza la hibridacion no radioactiva. |
| US5981179A (en) | 1991-11-14 | 1999-11-09 | Digene Diagnostics, Inc. | Continuous amplification reaction |
| ATE199158T1 (de) | 1991-12-23 | 2001-02-15 | Bayer Ag | Hbv amplifizierungssonden zur verwendung in hybridisierungssandwichassay in der lösungsphase |
| US5747244A (en) | 1991-12-23 | 1998-05-05 | Chiron Corporation | Nucleic acid probes immobilized on polystyrene surfaces |
| US5424413A (en) | 1992-01-22 | 1995-06-13 | Gen-Probe Incorporated | Branched nucleic acid probes |
| JP3414766B2 (ja) * | 1992-03-16 | 2003-06-09 | 株式会社ヤトロン | 単純ヘルペスウイルス２型の特異的検出方法 |
| ES2126002T3 (es) | 1992-09-15 | 1999-03-16 | Dow Chemical Co | Modificacion de la resistencia al choque de termoplasticos. |
| WO1994010335A2 (en) * | 1992-10-09 | 1994-05-11 | Amoco Corporation | Assay methods |
| JP3778925B2 (ja) | 1993-01-15 | 2006-05-24 | ザ パブリック ヘルス リサーチ インスティチュート オブ ザ シティー オブ ニューヨーク インク | 高感度核酸サンドイッチハイブリダイゼーション検定法及びキット |
| WO1994028156A1 (en) * | 1993-05-20 | 1994-12-08 | Dana-Farber Cancer Institute | Compositions and methods for treatment of herpesvirus infections |
| WO1995003430A1 (en) | 1993-07-23 | 1995-02-02 | Gen-Probe Incorporated | Methods for enhancing nucleic acid amplification |
| DE4331012A1 (de) | 1993-09-13 | 1995-03-16 | Bayer Ag | Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik |
| US5681697A (en) * | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| DK145493D0 (da) * | 1993-12-23 | 1993-12-23 | Dako As | Antistof |
| AUPM358894A0 (en) * | 1994-01-31 | 1994-02-24 | Csl Limited | Modified papilloma virus l2 protein and vlps formed therefrom |
| JP3738910B2 (ja) | 1994-04-04 | 2006-01-25 | バイエル コーポレーション | 特定の核酸配列を検出するためのハイブリダイゼーション−ライゲーション分析 |
| US5508168A (en) * | 1994-05-16 | 1996-04-16 | Hoffmann-La Roche Inc. | Methods and reagents for the detection of herpes simplex virus, treponema pallidum, and haemophilus ducreyi |
| CA2126952C (en) * | 1994-06-28 | 2010-12-14 | Sithian Pandian | Probe, kit, and method of amplification for increasing the sensitivity of nucleic acid hybridization assays |
| US5681702A (en) * | 1994-08-30 | 1997-10-28 | Chiron Corporation | Reduction of nonspecific hybridization by using novel base-pairing schemes |
| JP3093116B2 (ja) | 1994-09-30 | 2000-10-03 | 株式会社豊田中央研究所 | 核酸検出方法 |
| CA2163393C (en) * | 1994-11-30 | 2003-04-22 | Colleen Marie Nycz | Amplification and detection of mycobacteria nucleic acids |
| US6057099A (en) * | 1994-12-02 | 2000-05-02 | Intelligene Ltd. | Detection of nucleic acid sequences |
| US5747248A (en) | 1994-12-05 | 1998-05-05 | Chiron Corporation | Discontinuous probe design using hybritope mapping |
| US20030104361A1 (en) | 1997-09-29 | 2003-06-05 | Susan Weininger | Method of detection of nucleic acids with a specific sequence composition |
| CA2139070C (en) | 1994-12-23 | 2010-03-30 | Burton W. Blais | Method for enhancing detection ability of nucleic acid assays employing polymerase chain reaction |
| US5731153A (en) * | 1996-08-26 | 1998-03-24 | The Regents Of The University Of California | Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions |
| US5888724A (en) | 1995-02-17 | 1999-03-30 | The Trustees Of Columbia University In The City Of New York | Detection of high oncogenic-risk papilloma virus in high grade cervical lesions and cancers by a PCR/ELISA assay |
| EP0832280A2 (de) | 1995-06-07 | 1998-04-01 | Abbott Laboratories | Maskierungsmethode von proben zur reduktion des hintergrundes in der amplifikationsreaktion |
| US6083925A (en) * | 1995-06-07 | 2000-07-04 | Connaught Laboratories Limited | Nucleic acid respiratory syncytial virus vaccines |
| FR2737502B1 (fr) | 1995-07-31 | 1997-10-24 | Genset Sa | Procede de detection d'acides nucleiques utilisant des sondes nucleotidiques permettant a la fois une capture specifique et une detection |
| JP2000500342A (ja) | 1995-11-15 | 2000-01-18 | ジェン−プローブ・インコーポレーテッド | ヒトパピローマウイルス核酸に相補的な核酸プローブおよび関連する方法およびキット |
| CA2244891C (en) | 1996-02-09 | 2008-12-30 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| US5853993A (en) | 1996-10-21 | 1998-12-29 | Hewlett-Packard Company | Signal enhancement method and kit |
| US6117631A (en) | 1996-10-29 | 2000-09-12 | Polyprobe, Inc. | Detection of antigens via oligonucleotide antibody conjugates |
| GB9624165D0 (en) | 1996-11-19 | 1997-01-08 | Amdex A S | Use of nucleic acids bound to carrier macromolecules |
| US6110676A (en) * | 1996-12-04 | 2000-08-29 | Boston Probes, Inc. | Methods for suppressing the binding of detectable probes to non-target sequences in hybridization assays |
| US20020034737A1 (en) * | 1997-03-04 | 2002-03-21 | Hyseq, Inc. | Methods and compositions for detection or quantification of nucleic acid species |
| ATE340868T1 (de) * | 1997-05-02 | 2006-10-15 | Gen Probe Inc | Zwei-schritt hybridisierung und einfang von einem polynukleotid |
| WO1998059044A1 (en) | 1997-06-25 | 1998-12-30 | Tularik Inc. | High-throughput screening assays for modulators of primase activity |
| US6043038A (en) | 1998-03-31 | 2000-03-28 | Tularik, Inc. | High-throughput screening assays for modulators of primase activity |
| US5843995A (en) * | 1997-07-07 | 1998-12-01 | University Of Medicine And Dentistry Of New Jersey | Inhibition of HIV-1 replication using oligocarbamate derivatives |
| WO1999014377A2 (en) * | 1997-09-16 | 1999-03-25 | Innogenetics N.V. | Detection and identification of human papillomavirus by pcr and type-specific reverse hybridization |
| JP2002505071A (ja) * | 1997-11-04 | 2002-02-19 | ロシュ ダイアグノスティックス ゲーエムベーハー | 特異的かつ高感度な核酸検出方法 |
| US6355424B1 (en) * | 1997-12-12 | 2002-03-12 | Digene Corporation | Assessment of human papillomavirus-related disease |
| US6225053B1 (en) | 1997-12-12 | 2001-05-01 | Digene Corporation | Detection of hepatitis B virus |
| US20030096232A1 (en) * | 1997-12-19 | 2003-05-22 | Kris Richard M. | High throughput assay system |
| EP1865074B1 (de) | 1997-12-22 | 2011-04-20 | Hitachi Chemical Co., Ltd. | Direkte RT-PCR auf Oligonukleotid-immobilisierten PCR-Mikroplatten |
| WO1999036571A2 (en) | 1998-01-13 | 1999-07-22 | Biochip Technologies Gmbh | Method for the detection or nucleic acid of nucleic acid sequences |
| EP1051523A2 (de) | 1998-02-02 | 2000-11-15 | Amersham Pharmacia Biotech AB | Nuklein-säure analyse verfahren |
| US6686151B1 (en) | 1998-02-06 | 2004-02-03 | Digene Corporation | Immunological detection of RNA:DNA hybrids on microarrays |
| US7399589B2 (en) | 1998-02-06 | 2008-07-15 | Digene Corporation | Immunological detection of RNA:DNA hybrids on microarrays |
| US5994079A (en) | 1998-02-06 | 1999-11-30 | Digene Corporation | Direct detection of RNA mediated by reverse transcriptase lacking RNAse H function |
| CA2326099A1 (en) * | 1998-03-27 | 1999-10-07 | Habasit Ag | Transport belt with profiled surface and method for joining the two belt ends of such a transport belt |
| US6183956B1 (en) * | 1998-03-31 | 2001-02-06 | Tularik, Incorporated | High throughput in vitro screening assays for transcription modulators |
| US20010055766A1 (en) | 1999-04-02 | 2001-12-27 | Alexander Aristarkhov | Immunosorbant assay using branched bis-biotin/avidin/multiple label complex as a detection reagent |
| WO2000060116A1 (en) | 1999-04-02 | 2000-10-12 | Tropix, Inc. | High throughput and high sensitivity detection assays |
| US7019822B1 (en) | 1999-04-29 | 2006-03-28 | Mss, Inc. | Multi-grade object sorting system and method |
| US6544732B1 (en) * | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
| US6200746B1 (en) | 1999-08-25 | 2001-03-13 | Pharmacia & Upjohn Company | Methods of identifying anti-viral agents |
| US6893819B1 (en) * | 2000-11-21 | 2005-05-17 | Stratagene California | Methods for detection of a nucleic acid by sequential amplification |
| US6436662B1 (en) | 2000-04-04 | 2002-08-20 | Digene Corporation | Device and method for cytology slide preparation |
| US6521190B1 (en) | 2000-05-19 | 2003-02-18 | Digene Corporation | Cell collection apparatus |
| US6828098B2 (en) * | 2000-05-20 | 2004-12-07 | The Regents Of The University Of Michigan | Method of producing a DNA library using positional amplification based on the use of adaptors and nick translation |
| US7439016B1 (en) * | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| US7601497B2 (en) | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| AU1548802A (en) | 2000-06-21 | 2002-01-02 | Digene Corp | Universal collection medium |
| SI1421200T1 (sl) | 2001-08-23 | 2007-04-30 | Merck & Co Inc | Poskusi PCR fluorescentnih multipleks HPV-jev z uporabo vec fluoroforov |
| US20050032105A1 (en) | 2001-10-12 | 2005-02-10 | Bair Robert Jackson | Compositions and methods for using a solid support to purify DNA |
| US6977148B2 (en) | 2001-10-15 | 2005-12-20 | Qiagen Gmbh | Multiple displacement amplification |
| NZ533703A (en) | 2002-01-07 | 2006-05-26 | Norchip As | Method for detecting human papillomavirus mRNA |
| CA2525482C (en) | 2003-04-04 | 2015-02-17 | F. Hoffmann-La Roche Ag | Improved system for multicolor real-time pcr comprising 3 to 6 pairs of forester resonance energy transfer (fret) probes |
| EP1641809B2 (de) | 2003-07-05 | 2018-10-03 | The Johns Hopkins University | Verfahren und zusammensetzungen zum nachweis und zur auflistung genetischer variationen |
| CA2594771A1 (en) | 2005-01-14 | 2006-07-20 | The Regents Of The University Of Michigan | Systems, methods, and compositions for detection of human papilloma virus in biological samples |
| US20060240449A1 (en) | 2005-01-19 | 2006-10-26 | Mcglennen Ronald C | Methods and compositions for preparation of biological samples |
| JP2009517002A (ja) | 2005-04-06 | 2009-04-30 | ヴェレニウム コーポレイション | 化学及び生物兵器の広域特異性除染のための酵素及び処方物 |
| US7972776B2 (en) | 2005-11-15 | 2011-07-05 | Oncohealth Corporation | Protein chips for HPV detection |
| WO2007130519A2 (en) | 2006-05-02 | 2007-11-15 | Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Viral nucleic acid microarray and method of use |
| ES2412432T3 (es) | 2007-02-27 | 2013-07-11 | Nuclea Biomarkers Llc | Método para predecir la respuesta de pacientes de nsclc al tratamiento mediante un inhibidor de egfr-tk |
| US7985375B2 (en) | 2007-04-06 | 2011-07-26 | Qiagen Gaithersburg, Inc. | Sample preparation system and method for processing clinical specimens |
| JPWO2008139938A1 (ja) | 2007-05-02 | 2010-08-05 | 国立大学法人 東京医科歯科大学 | ヒトパピローマウイルス１６型遺伝子を標的とする二本鎖核酸分子及びそれを含む医薬 |
| JP2009106220A (ja) | 2007-10-31 | 2009-05-21 | Genodive Pharma Kk | 基板上での等温増幅反応による標的塩基配列の捕捉及び検出方法 |
| DK2209920T3 (en) | 2007-11-01 | 2016-08-15 | Self-Screen B V | NEW CERVIX-HPV DETECTION PROCEDURE |
| WO2009123996A2 (en) | 2008-03-31 | 2009-10-08 | The Ohio State University Research Foundation | Hybridization quantitation method for modified micro-rna and -dna based oligonucleotides |
| EP2262911B1 (de) | 2008-04-17 | 2016-10-12 | QIAGEN Gaithersburg, Inc. | Zusammensetzungen, verfahren und kits mit synthetischen sonden zum nachweis der anwesenheit einer target-nukleinsäure |
| WO2010004251A1 (en) | 2008-06-16 | 2010-01-14 | Oncomethylome Sciences Sa | Dna methylomes |
| WO2010028382A2 (en) | 2008-09-05 | 2010-03-11 | Mayo Foundation For Medical Education And Research | Collecting and processing complex macromolecular mixtures |
| US9090948B2 (en) | 2008-09-30 | 2015-07-28 | Abbott Molecular Inc. | Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples |
| EP2184368A1 (de) | 2008-11-07 | 2010-05-12 | DKFZ Deutsches Krebsforschungszentrum | Diagnosetranskript- und Spleißmuster von HPV16 bei verschiedenen Halsverletzungen |
| JP5738278B2 (ja) | 2009-05-01 | 2015-06-24 | キアジェン ゲイサーズバーグ インコーポレイテッド | 試料中のｒｎａスプライシング形態を検出するための非標的増幅法 |
-
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