ATE545712T1 - Verfahren mit verwendung von poren - Google Patents
Verfahren mit verwendung von porenInfo
- Publication number
- ATE545712T1 ATE545712T1 AT06808555T AT06808555T ATE545712T1 AT E545712 T1 ATE545712 T1 AT E545712T1 AT 06808555 T AT06808555 T AT 06808555T AT 06808555 T AT06808555 T AT 06808555T AT E545712 T1 ATE545712 T1 AT E545712T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleotide
- pore
- relates
- pores
- identity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/60—Detection means characterised by use of a special device
- C12Q2565/631—Detection means characterised by use of a special device being a biochannel or pore
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Nanotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0523282.2A GB0523282D0 (en) | 2005-11-15 | 2005-11-15 | Methods using pores |
PCT/GB2006/004265 WO2007057668A1 (en) | 2005-11-15 | 2006-11-15 | Methods using pores |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE545712T1 true ATE545712T1 (de) | 2012-03-15 |
Family
ID=35516986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06808555T ATE545712T1 (de) | 2005-11-15 | 2006-11-15 | Verfahren mit verwendung von poren |
Country Status (16)
Country | Link |
---|---|
US (2) | US8105846B2 (de) |
EP (2) | EP1951898B1 (de) |
JP (1) | JP5328362B2 (de) |
KR (1) | KR20080083281A (de) |
CN (1) | CN101356288B (de) |
AT (1) | ATE545712T1 (de) |
AU (1) | AU2006314296B2 (de) |
BR (1) | BRPI0618391A2 (de) |
CA (1) | CA2629009C (de) |
GB (1) | GB0523282D0 (de) |
IL (1) | IL191319A (de) |
MY (1) | MY149161A (de) |
NZ (1) | NZ568163A (de) |
RU (1) | RU2008123842A (de) |
UA (1) | UA95087C2 (de) |
WO (1) | WO2007057668A1 (de) |
Families Citing this family (89)
Publication number | Priority date | Publication date | Assignee | Title |
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GB0523282D0 (en) | 2005-11-15 | 2005-12-21 | Isis Innovation | Methods using pores |
US9121843B2 (en) | 2007-05-08 | 2015-09-01 | Trustees Of Boston University | Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof |
GB2453377A (en) * | 2007-10-05 | 2009-04-08 | Isis Innovation | Transmembrane protein pores and molecular adapters therefore. |
AU2009269792A1 (en) * | 2008-07-07 | 2010-01-14 | Oxford Nanopore Technologies Limited | Base-detecting pore |
US20110229877A1 (en) * | 2008-07-07 | 2011-09-22 | Oxford Nanopore Technologies Limited | Enzyme-pore constructs |
EP2342359B1 (de) * | 2008-08-01 | 2015-03-04 | Brown University | System und verfahren zur bestimmung von molekülen anhand von massenspektrometrie sowie entsprechende verfahren |
GB0820927D0 (en) * | 2008-11-14 | 2008-12-24 | Isis Innovation | Method |
WO2010062903A2 (en) * | 2008-11-26 | 2010-06-03 | Board Of Regents, The University Of Texas System | Genomic sequencing using modified protein pores and ionic liquids |
KR20110125226A (ko) | 2009-01-30 | 2011-11-18 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 혼성화 링커 |
KR101797773B1 (ko) | 2009-01-30 | 2017-11-15 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 막횡단 시퀀싱에서 핵산 구축물용 어댑터 |
GB0905140D0 (en) * | 2009-03-25 | 2009-05-06 | Isis Innovation | Method |
US9017937B1 (en) | 2009-04-10 | 2015-04-28 | Pacific Biosciences Of California, Inc. | Nanopore sequencing using ratiometric impedance |
US8986928B2 (en) | 2009-04-10 | 2015-03-24 | Pacific Biosciences Of California, Inc. | Nanopore sequencing devices and methods |
CA2808576A1 (en) | 2009-09-30 | 2011-04-07 | Quantapore, Inc. | Ultrafast sequencing of biological polymers using a labeled nanopore |
KR101814056B1 (ko) | 2009-12-01 | 2018-01-02 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 생화학적 분석 기구 |
GB2490846A (en) * | 2010-03-05 | 2012-11-14 | Univ Utah Res Found | Detection of nucleic acid lesions and adducts using nanopores |
US9005425B2 (en) | 2010-03-05 | 2015-04-14 | University Of Utah Research Foundation | Detection of nucleic acid lesions and adducts using nanopores |
US8652779B2 (en) | 2010-04-09 | 2014-02-18 | Pacific Biosciences Of California, Inc. | Nanopore sequencing using charge blockade labels |
EP2622343B1 (de) | 2010-10-01 | 2016-01-20 | Oxford Nanopore Technologies Limited | Biochemisches analysegerät und drehventil |
US8673757B2 (en) | 2010-10-28 | 2014-03-18 | International Business Machines Corporation | Structure and method for using high-k material as an etch stop layer in dual stress layer process |
CA2826374C (en) | 2011-02-11 | 2024-01-23 | Oxford Nanopore Technologies Limited | Mutant pores |
CA2837306C (en) | 2011-05-27 | 2020-03-10 | Oxford Nanopore Technologies Limited | Determining the presence, absence or characteristics of an analyte coupled to a membrane |
RU2467218C1 (ru) * | 2011-06-16 | 2012-11-20 | Закрытое Акционерное Общество "Научно-производственное объединение "Гидравлические аппараты" (ЗАО "НПО "Гидроаппарат") | Гидромуфта |
CN103328973B (zh) * | 2011-07-20 | 2015-04-01 | 加利福尼亚大学董事会 | 双孔装置 |
AU2012288629B2 (en) | 2011-07-25 | 2017-02-02 | Oxford Nanopore Technologies Limited | Hairpin loop method for double strand polynucleotide sequencing using transmembrane pores |
JP6226869B2 (ja) | 2011-10-21 | 2017-11-08 | オックスフォード ナノポール テクノロジーズ リミテッド | 酵素法 |
US9617591B2 (en) | 2011-12-29 | 2017-04-11 | Oxford Nanopore Technologies Ltd. | Method for characterising a polynucleotide by using a XPD helicase |
CN104126018B (zh) | 2011-12-29 | 2021-09-14 | 牛津纳米孔技术公司 | 酶方法 |
EP2815235B1 (de) | 2012-02-15 | 2020-04-15 | Oxford Nanopore Technologies Limited | Aptamer verfahren |
MY175528A (en) * | 2012-04-02 | 2020-07-01 | Lux Bio Group Inc | Apparatus and method for molecular separation, purification, and sensing |
AU2013246702B2 (en) | 2012-04-10 | 2017-06-15 | Oxford Nanopore Technologies Limited | Mutant lysenin pores |
BR112015001054A8 (pt) | 2012-07-19 | 2022-08-02 | Oxford Nanopore Tech Ltd | Helicase monomérica que é membro da superfamília 1 ou superfamília 2, helicase hel308 isolada, método para caracterizar um polinucleotídeo alvo, e, sensor para a caracterização de um polinucleotídeo alvo |
BR112015001052B8 (pt) * | 2012-07-19 | 2022-12-27 | Oxford Nanopore Tech Ltd | Métodos para distinguir um polinucleotídeo alvo,sensor para distinguir um polinucleotídeo alvo, e, uso de um construto |
US11155860B2 (en) | 2012-07-19 | 2021-10-26 | Oxford Nanopore Technologies Ltd. | SSB method |
EP2895618B1 (de) | 2012-09-14 | 2017-07-26 | Oxford Nanopore Technologies Limited | Probenvorbereitungsverfahren |
US9651539B2 (en) | 2012-10-28 | 2017-05-16 | Quantapore, Inc. | Reducing background fluorescence in MEMS materials by low energy ion beam treatment |
US9995728B2 (en) | 2012-11-06 | 2018-06-12 | Oxford Nanopore Technologies Ltd. | Quadruplex method |
EP2964779B1 (de) | 2013-03-08 | 2018-08-29 | Oxford Nanopore Technologies Limited | Verwendung von spacer-elementen in einer nukleinsäure zur kontrolle der bewegung einer helicase |
GB201318465D0 (en) | 2013-10-18 | 2013-12-04 | Oxford Nanopore Tech Ltd | Method |
GB201314695D0 (en) | 2013-08-16 | 2013-10-02 | Oxford Nanopore Tech Ltd | Method |
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CN117947149A (zh) | 2013-10-18 | 2024-04-30 | 牛津纳米孔科技公开有限公司 | 经修饰的酶 |
CN111534504B (zh) | 2014-01-22 | 2024-06-21 | 牛津纳米孔科技公开有限公司 | 将一个或多个多核苷酸结合蛋白连接到靶多核苷酸的方法 |
GB201406155D0 (en) | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
GB201403096D0 (en) | 2014-02-21 | 2014-04-09 | Oxford Nanopore Tech Ltd | Sample preparation method |
US10337060B2 (en) | 2014-04-04 | 2019-07-02 | Oxford Nanopore Technologies Ltd. | Method for characterising a double stranded nucleic acid using a nano-pore and anchor molecules at both ends of said nucleic acid |
US10167503B2 (en) | 2014-05-02 | 2019-01-01 | Oxford Nanopore Technologies Ltd. | Mutant pores |
GB201417712D0 (en) | 2014-10-07 | 2014-11-19 | Oxford Nanopore Tech Ltd | Method |
GB201411285D0 (en) | 2014-06-25 | 2014-08-06 | Prosser Joseph | Sequencer |
CN114605507A (zh) | 2014-09-01 | 2022-06-10 | 弗拉芒区生物技术研究所 | 突变csgg孔 |
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CN107109479B (zh) * | 2014-10-31 | 2021-07-06 | 吉尼亚科技公司 | 具有改变的特征的α-溶血素变体 |
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WO2010034018A2 (en) | 2008-09-22 | 2010-03-25 | University Of Washington | Msp nanopores and related methods |
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2005
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2006
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- 2006-11-15 AT AT06808555T patent/ATE545712T1/de active
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Also Published As
Publication number | Publication date |
---|---|
US8785211B2 (en) | 2014-07-22 |
CN101356288A (zh) | 2009-01-28 |
AU2006314296B2 (en) | 2012-08-23 |
NZ568163A (en) | 2011-11-25 |
US8105846B2 (en) | 2012-01-31 |
EP2272981B1 (de) | 2013-01-09 |
CA2629009A1 (en) | 2007-05-24 |
WO2007057668A1 (en) | 2007-05-24 |
CN101356288B (zh) | 2016-02-03 |
US20120219960A1 (en) | 2012-08-30 |
MY149161A (en) | 2013-07-31 |
IL191319A (en) | 2011-10-31 |
EP2272981A1 (de) | 2011-01-12 |
KR20080083281A (ko) | 2008-09-17 |
GB0523282D0 (en) | 2005-12-21 |
EP1951898B1 (de) | 2012-02-15 |
EP1951898A1 (de) | 2008-08-06 |
RU2008123842A (ru) | 2009-12-27 |
CA2629009C (en) | 2016-02-02 |
JP5328362B2 (ja) | 2013-10-30 |
AU2006314296A1 (en) | 2007-05-24 |
JP2009519705A (ja) | 2009-05-21 |
BRPI0618391A2 (pt) | 2011-08-30 |
UA95087C2 (en) | 2011-07-11 |
US20080311582A1 (en) | 2008-12-18 |
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