ATE522203T1 - Pharmazeutische herstellung zur bindung von acetaldehyd in speichel, magen und dickdarm - Google Patents

Pharmazeutische herstellung zur bindung von acetaldehyd in speichel, magen und dickdarm

Info

Publication number
ATE522203T1
ATE522203T1 AT01980581T AT01980581T ATE522203T1 AT E522203 T1 ATE522203 T1 AT E522203T1 AT 01980581 T AT01980581 T AT 01980581T AT 01980581 T AT01980581 T AT 01980581T AT E522203 T1 ATE522203 T1 AT E522203T1
Authority
AT
Austria
Prior art keywords
saliva
stomach
large intestine
pharmaceutical production
binding acetaldehyde
Prior art date
Application number
AT01980581T
Other languages
English (en)
Inventor
Mikko Salaspuro
Martti Marvola
Original Assignee
Biohit Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohit Oyj filed Critical Biohit Oyj
Application granted granted Critical
Publication of ATE522203T1 publication Critical patent/ATE522203T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT01980581T 2000-10-30 2001-10-30 Pharmazeutische herstellung zur bindung von acetaldehyd in speichel, magen und dickdarm ATE522203T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20002392A FI121528B (fi) 2000-10-30 2000-10-30 Farmaseuttinen koostumus syöpään sairastumisen riskin vähentämiseen paikallisesti sitomalla asetaldehydi syljessä, mahalaukussa tai paksusuolessa
PCT/FI2001/000948 WO2002036098A1 (en) 2000-10-30 2001-10-30 Method and preparation for binding acetaldehyde in saliva, stomach and large intestine

Publications (1)

Publication Number Publication Date
ATE522203T1 true ATE522203T1 (de) 2011-09-15

Family

ID=8559405

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01980581T ATE522203T1 (de) 2000-10-30 2001-10-30 Pharmazeutische herstellung zur bindung von acetaldehyd in speichel, magen und dickdarm

Country Status (10)

Country Link
US (1) US9474733B2 (de)
EP (1) EP1339394B1 (de)
JP (1) JP4691312B2 (de)
CN (1) CN100467016C (de)
AT (1) ATE522203T1 (de)
AU (1) AU2002212395A1 (de)
EA (1) EA009335B1 (de)
ES (1) ES2370811T3 (de)
FI (1) FI121528B (de)
WO (1) WO2002036098A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006037848A1 (en) * 2004-10-08 2006-04-13 Biohit Oyj Method and preparation for binding aldehydes in saliva
FI121528B (fi) 2000-10-30 2010-12-31 Biohit Oyj Farmaseuttinen koostumus syöpään sairastumisen riskin vähentämiseen paikallisesti sitomalla asetaldehydi syljessä, mahalaukussa tai paksusuolessa
WO2002041837A2 (en) 2000-11-22 2002-05-30 Rxkinetix, Inc. Treatment of mucositis
ITME20040015A1 (it) * 2004-12-07 2005-03-07 Vincenzo Savica Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico.
FI122914B (fi) * 2005-04-01 2012-08-31 Biohit Oyj Elintarvikekoostumus asetaldehydin sitomiseksi suussa ja ruoansulatuskanavassa ja menetelmä koostumuksen valmistamiseksi
US20090028951A1 (en) * 2005-07-13 2009-01-29 Al Czap Compositions for Oral Administration of Sustained Release Glutathione, Methods for Their Production and Uses Thereof
CA2635603C (en) 2005-11-30 2016-01-19 Endo Pharmaceuticals Inc. Treatment of xerostomia
FI20060501A7 (fi) * 2006-05-22 2007-11-23 Biohit Oyj Koostumus ja menetelmä asetaldehydin sitomiseksi mahalaukussa
US20100166833A1 (en) * 2007-05-07 2010-07-01 Technion Research & Development Foundation Ltd. Compositions, articles and methods for preventing or reducing tobacco-associated damage
FI120526B (fi) * 2007-05-16 2009-11-30 Biohit Oyj Filtteri tupakkatuotteeseen
FI20070705A7 (fi) * 2007-09-14 2009-06-02 Biohit Oyj Asetaldehydin sitominen suussa ja mahalaukussa
US20090092664A1 (en) * 2007-10-08 2009-04-09 University Of Kentucky Research Foundation Polymer-metal chelator conjugates and uses thereof
IL188681A0 (en) 2008-01-09 2008-12-29 Amino Acid Solutions Inc Pharmaceutical compositions and methods utilizing a d-amino acid
FI20115680A7 (fi) * 2011-06-29 2012-12-30 Biohit Oyj Nestemäisiä farmaseuttisia koostumuksia tai yhdistelmätuotteita
FI129157B (en) 2012-05-28 2021-08-13 Biohit Oyj Composition for use in reducing the incidence of or preventing severe headaches
FI20135097A7 (fi) * 2013-02-01 2014-08-02 Biohit Oyj Koostumus aldehydien sitomiseen suussa
BR112015006048A2 (pt) 2013-03-12 2017-07-04 Biohit Oyj composição encapsulada para ligação com aldeídos no estômago
KR20150126383A (ko) 2013-03-12 2015-11-11 바이오히트 오와이제이 위장관 내의 알데하이드에 결합하는 경구 투여용 조성물
FI20145217A7 (fi) 2014-03-06 2015-09-07 Biohit Oyj Koostumus aldehydien ja vapaiden radikaalien sitomiseksi ruoansulatuskanavassa
CN108671232A (zh) * 2018-07-09 2018-10-19 珠海中科先进技术研究院有限公司 一种能够降低体内乙醛浓度的组合制剂及其制备方法与用途
SG11202108530VA (en) 2019-03-15 2021-09-29 Novo Nordisk As Process for spray drying a glp-1 peptide
US11717554B2 (en) * 2019-09-19 2023-08-08 Max R&D Llc Method for preventing or treating hangover symptom(s) associated with consumption of alcoholic beverage(s)
CN119214993A (zh) * 2024-09-27 2024-12-31 国家纳米科学中心 用于清除醛基的透明质酸纳米凝胶、其制备方法和应用

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0054795B1 (de) * 1980-12-09 1987-07-15 Teijin Limited Halogenierte Prostacycline, Verfahren zu ihrer Herstellung und ihre Anwendung in der Pharmazie
US4496548A (en) 1983-02-04 1985-01-29 Moldowan Mervin J Composition and method for reducing hangover
GB8313044D0 (en) 1983-05-12 1983-06-15 Caseley J R Reducing toxic effects of tobacco
US4528295A (en) * 1983-08-15 1985-07-09 Boris Tabakoff Composition and method for reducing blood acetaldehyde levels
JPS6116144A (ja) 1984-06-29 1986-01-24 Fujitsu Ten Ltd 異常シフト警報装置
US5202354A (en) * 1986-02-18 1993-04-13 Takeda Chemical Industries, Ltd. Composition and method for reducing acetaldehyde toxicity
PH22818A (en) 1986-02-18 1989-01-19 Takeda Chemical Industries Ltd Composition and method for reducing acetaldehyde toxicity
JPS62195323A (ja) * 1986-02-24 1987-08-28 Eisai Co Ltd 胃内滞留型粒子
GB2201594B (en) * 1986-06-24 1991-02-13 Istvan Racz Production of acid binding pharmaceutical preparations
ATE71293T1 (de) * 1986-09-18 1992-01-15 London Pharmacy Innovation Arzneiformulierung.
HU201865B (en) 1989-04-28 1991-01-28 Pecsi Dohanygyar Tobacco-smoke filter of high efficiency
JPH0374327A (ja) 1989-08-16 1991-03-28 Ajinomoto Co Inc アルコール代謝促進剤
JPH03136895A (ja) 1989-10-23 1991-06-11 Fuji Electric Co Ltd 光情報記録媒体の製造方法
JPH0421635A (ja) 1990-05-16 1992-01-24 Suntory Ltd アセトアルデヒドの毒性抑制剤およびアセトアルデヒドの毒性抑制に有効な飲食物
US5110423A (en) * 1990-05-25 1992-05-05 Technic Inc. Bath for electroplating bright tin or tin-lead alloys and method thereof
JP3013860B2 (ja) 1991-03-22 2000-02-28 三菱瓦斯化学株式会社 食品保存剤およびこれを用いた食品の保存方法
FI93924C (fi) * 1991-09-17 1995-06-26 Martti Lauri Antero Marvola Menetelmä säädellysti lääkeainetta vapauttavan valmisteen valmistamiseksi
US5169638A (en) * 1991-10-23 1992-12-08 E. R. Squibb & Sons, Inc. Buoyant controlled release powder formulation
JP3479986B2 (ja) 1992-10-07 2003-12-15 大正製薬株式会社 アルコール性肝障害予防用組成物
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
US5695781A (en) * 1995-03-01 1997-12-09 Hallmark Pharmaceuticals, Inc. Sustained release formulation containing three different types of polymers
JPH09194361A (ja) * 1996-01-19 1997-07-29 Wakunaga Pharmaceut Co Ltd 抗腫瘍剤
WO1998003260A1 (en) 1996-07-22 1998-01-29 Kouki Bussan Yugenkaisha Novel adsorbent
IN186245B (de) * 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US5829449A (en) 1997-09-19 1998-11-03 Thione International, Inc. Smoking products containing antioxidants
US5922346A (en) 1997-12-01 1999-07-13 Thione International, Inc. Antioxidant preparation
WO2000071145A1 (en) 1999-05-24 2000-11-30 Hee Jung Kim Composition for recovering from a hangover and for preventing brain cell damage
AU780261B2 (en) * 1999-10-29 2005-03-10 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
FI121528B (fi) 2000-10-30 2010-12-31 Biohit Oyj Farmaseuttinen koostumus syöpään sairastumisen riskin vähentämiseen paikallisesti sitomalla asetaldehydi syljessä, mahalaukussa tai paksusuolessa
ITPI20010014A1 (it) 2001-03-05 2002-09-05 Ivo Pera Composto per filtri per sigarette,o altri articoli da fumo,a base di sostanze antiossidanti ed il filtro cosi'ottenuto
JP2003055215A (ja) 2001-06-05 2003-02-26 Ajinomoto Co Inc 肝線維化抑制剤
WO2002098405A1 (fr) 2001-06-05 2002-12-12 Ajinomoto Co., Inc. Inhibiteurs de fibrose du foie
US6936283B2 (en) 2003-07-25 2005-08-30 Langeland Bjoern T. Composition for stimulation of specific metallo-enzymes
EA011721B1 (ru) 2004-02-17 2009-04-28 Маркус Граф В. Матушка-Грейффенклау Композиция для сдерживания деградации алкоголя в организме человека

Also Published As

Publication number Publication date
US9474733B2 (en) 2016-10-25
FI20002392A0 (fi) 2000-10-30
JP4691312B2 (ja) 2011-06-01
EP1339394A1 (de) 2003-09-03
FI20002392L (fi) 2002-05-01
AU2002212395A1 (en) 2002-05-15
ES2370811T3 (es) 2011-12-23
CN1486177A (zh) 2004-03-31
EP1339394B1 (de) 2011-08-31
JP2004512353A (ja) 2004-04-22
WO2002036098A1 (en) 2002-05-10
EA009335B1 (ru) 2007-12-28
FI121528B (fi) 2010-12-31
CN100467016C (zh) 2009-03-11
EA200300532A1 (ru) 2003-10-30
US20050267042A1 (en) 2005-12-01

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