ATE456581T1 - Antikörper gegen il21-rezeptor und deren verwendung - Google Patents
Antikörper gegen il21-rezeptor und deren verwendungInfo
- Publication number
- ATE456581T1 ATE456581T1 AT04720349T AT04720349T ATE456581T1 AT E456581 T1 ATE456581 T1 AT E456581T1 AT 04720349 T AT04720349 T AT 04720349T AT 04720349 T AT04720349 T AT 04720349T AT E456581 T1 ATE456581 T1 AT E456581T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- receptor
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45433603P | 2003-03-14 | 2003-03-14 | |
PCT/US2004/007444 WO2004083249A2 (en) | 2003-03-14 | 2004-03-12 | Antibodies against human il-21 receptor and uses therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE456581T1 true ATE456581T1 (de) | 2010-02-15 |
Family
ID=33029874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04720349T ATE456581T1 (de) | 2003-03-14 | 2004-03-12 | Antikörper gegen il21-rezeptor und deren verwendung |
Country Status (20)
Country | Link |
---|---|
US (2) | US7495085B2 (de) |
EP (2) | EP2184298A1 (de) |
JP (1) | JP4914209B2 (de) |
KR (1) | KR20050119120A (de) |
CN (2) | CN102040662A (de) |
AR (1) | AR043616A1 (de) |
AT (1) | ATE456581T1 (de) |
AU (1) | AU2004221876B2 (de) |
BR (1) | BRPI0408315A (de) |
CA (1) | CA2518371A1 (de) |
CL (1) | CL2004000534A1 (de) |
CO (1) | CO5660297A2 (de) |
DE (1) | DE602004025332D1 (de) |
ES (1) | ES2340280T3 (de) |
MX (1) | MXPA05009556A (de) |
NO (1) | NO20054170L (de) |
NZ (1) | NZ542306A (de) |
RU (1) | RU2005131852A (de) |
WO (1) | WO2004083249A2 (de) |
ZA (1) | ZA200507067B (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6057128A (en) | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
MXPA05000655A (es) * | 2002-07-15 | 2006-02-22 | Harvard College | Metodos y composiciones para modular el desarrollo y la funcion de las celulas t helper (th). |
NZ542306A (en) | 2003-03-14 | 2008-04-30 | Wyeth Corp | Antibodies against human IL-21 receptor and uses therefor |
RU2005132458A (ru) * | 2003-03-21 | 2006-03-20 | Уайт (Us) | Лечение иммунологических расстройств с использованием агонистов интерлейкина-21/рецептора интерлейкина-21 |
EP1687026B1 (de) | 2003-11-21 | 2008-05-14 | UCB Pharma, S.A. | Verfahren zur behandlung von multipler sklerose durch hemmung der il-17-aktivität |
CA2566333A1 (en) * | 2004-05-19 | 2005-12-01 | Wyeth | Modulation of immunoglobulin production and atopic disorders |
CA2574848A1 (en) * | 2004-08-05 | 2006-12-21 | Wyeth | Antagonizing interleukin-21 receptor activity |
EP2336324A2 (de) | 2005-03-25 | 2011-06-22 | National Research Council of Canada | Verfahren zur Isolation von löslichen Polypeptiden |
GT200600148A (es) | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis | |
PT1963369E (pt) * | 2005-11-28 | 2013-05-28 | Zymogenetics Inc | Antagonistas de il-21 |
EP1960433A2 (de) * | 2005-11-28 | 2008-08-27 | Zymogenetics, Inc. | Il-21 rezeptor antagonisten |
US9005974B2 (en) | 2005-12-09 | 2015-04-14 | Academish Medisch Centrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
FI1974017T4 (fi) | 2005-12-09 | 2023-09-14 | Välineitä ja menetelmiä, joilla voidaan vaikuttaa vasta-ainetta tuottavien solujen stabiliteettiin | |
WO2007109747A2 (en) * | 2006-03-21 | 2007-09-27 | Wyeth | Methods and compositions for antagonism of rage |
WO2008092084A2 (en) * | 2007-01-26 | 2008-07-31 | Centocor, Inc. | Injectable non-aqueous suspension with high concentration of therapeutic agent |
KR101163295B1 (ko) | 2007-06-29 | 2012-07-05 | 에프. 호프만-라 로슈 아게 | 향상된 면역글로불린을 생산하는 중쇄 돌연변이체 |
WO2009023267A2 (en) * | 2007-08-15 | 2009-02-19 | President And Fellows Of Harvard College | Methods for modulating development and expansion of il-17 expressing cells |
ES2572231T3 (es) * | 2007-12-07 | 2016-05-30 | Zymogenetics Inc | Anticuerpos monoclonales anti-IL-21 humana |
WO2009111889A1 (en) * | 2008-03-13 | 2009-09-17 | The Hospital For Sick Children | Lymphocyte control of obesity and insulin resistance |
US8178097B2 (en) * | 2008-05-23 | 2012-05-15 | Wyeth Llc | Methods of treatment utilizing binding proteins of the interleukin-21 receptor |
AR071885A1 (es) * | 2008-05-23 | 2010-07-21 | Wyeth Corp | Proteinas de union al receptor de interleuquina 21 |
JP2012504939A (ja) * | 2008-09-23 | 2012-03-01 | ワイス・エルエルシー | 架橋結合タンパク質による活性化シグナルの産生を予測するための方法 |
WO2010132532A1 (en) * | 2009-05-15 | 2010-11-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | B cell surface reactive antibodies |
JP5781508B2 (ja) | 2009-07-15 | 2015-09-24 | アイム・セラピューティクス・べー・フェー | 高親和性抗体を産生させるための手段および方法 |
EP2596023A4 (de) * | 2010-07-20 | 2014-03-05 | Beth Israel Hospital | Zusammensetzungen und verfahren mit il-6- und il-21-antagonisten |
EP2646466B1 (de) | 2010-12-02 | 2017-03-29 | AIMM Therapeutics B.V. | Mittel und methoden zur produktion von hoch affinen antikörpern |
MX2013012593A (es) * | 2011-04-29 | 2014-08-21 | Selecta Biosciences Inc | Nanoportadores sintéticos tolerogénicos para reducir las respuestas de anticuerpos. |
US9309318B2 (en) * | 2012-10-17 | 2016-04-12 | Amgen, Inc. | Compositions relating to anti-IL-21 receptor antibodies |
UY35457A (es) | 2013-03-14 | 2014-10-31 | Bayer Healthcare Llc | ANTICUERPOS MONOCLONALES CONTRA ANTITROMBINA ß |
WO2015115892A1 (en) | 2014-01-31 | 2015-08-06 | Aimm Therapeutics B.V. | Means and methods for producing stable antibodies |
AR099625A1 (es) | 2014-03-21 | 2016-08-03 | Lilly Co Eli | Anticuerpos de il-21 |
SG10201913627TA (en) * | 2014-04-08 | 2020-03-30 | Boston Pharmaceuticals Inc | Binding molecules specific for il-21 and uses thereof |
WO2017075440A1 (en) * | 2015-10-30 | 2017-05-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Targeted cancer therapy |
CN109069600B (zh) * | 2016-03-31 | 2023-03-28 | 伊莱利利公司 | Il-21抗体及其用途 |
ES2949342T3 (es) * | 2016-06-17 | 2023-09-27 | Medigene Immunotherapies Gmbh | Receptores de células T y usos de los mismos |
US20190185559A1 (en) * | 2016-09-02 | 2019-06-20 | The Brigham And Women's Hospital, Inc. | Compositions and methods for treating neoplasias |
WO2019052562A1 (zh) * | 2017-09-15 | 2019-03-21 | 科济生物医药(上海)有限公司 | Il-4r的融合蛋白及其应用 |
EP3990004A4 (de) * | 2019-06-26 | 2023-06-07 | The Johns Hopkins University | Verfahren und materialien zur gezielten expansion von regulatorischen t-zellen |
MX2022007960A (es) * | 2019-12-24 | 2022-07-12 | Dizal Jiangsu Pharmaceutical Co Ltd | Nuevos anticuerpos anti-fgfr2b. |
US12012441B2 (en) | 2020-10-26 | 2024-06-18 | Neptune Biosciences Llc | Engineered human IL-21 cytokines and methods for using the same |
WO2023023150A2 (en) * | 2021-08-18 | 2023-02-23 | Hifibio (Hk) Limited | Methods and compositions related to neutralizing antibodies against human coronavirus |
WO2024040194A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
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EP3214175A1 (de) | 1999-08-24 | 2017-09-06 | E. R. Squibb & Sons, L.L.C. | Humane ctla-4-antikörper und verwendungen davon |
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JP2003523179A (ja) | 1999-11-18 | 2003-08-05 | シェーリング コーポレイション | 哺乳動物レセプタータンパク質;関連する試薬および方法 |
AU2001233034A1 (en) | 2000-01-27 | 2001-08-07 | American Cyanamid Company | Method for preparing alpha-sulfonyl hydroxamic acid derivatives |
ES2339959T3 (es) * | 2000-04-05 | 2010-05-27 | Zymogenetics, Inc. | Receptores de citoquina zalza11 solubles. |
EP1353953B1 (de) * | 2000-05-11 | 2006-11-29 | Genetics Institute, LLC | Mu-1, ein mitglied der cytokine rezeptor familie |
KR101155294B1 (ko) * | 2000-06-16 | 2013-03-07 | 캠브리지 안티바디 테크놀로지 리미티드 | 면역특이적으로 BLyS에 결합하는 항체 |
EP1432431B1 (de) * | 2001-10-04 | 2017-05-10 | Genetics Institute LLC | Verfahren und zusammensetzungen zur modulierung der wirkung des interleukin-21 |
JP2005508179A (ja) | 2001-11-05 | 2005-03-31 | ザイモジェネティクス,インコーポレイティド | Il−21アンタゴニスト |
US20040016010A1 (en) * | 2002-04-17 | 2004-01-22 | Marion Kasaian | IL-21 receptor knockout animal and methods of use thereof |
MXPA05000655A (es) | 2002-07-15 | 2006-02-22 | Harvard College | Metodos y composiciones para modular el desarrollo y la funcion de las celulas t helper (th). |
NZ542306A (en) | 2003-03-14 | 2008-04-30 | Wyeth Corp | Antibodies against human IL-21 receptor and uses therefor |
RU2005132458A (ru) * | 2003-03-21 | 2006-03-20 | Уайт (Us) | Лечение иммунологических расстройств с использованием агонистов интерлейкина-21/рецептора интерлейкина-21 |
CA2566333A1 (en) | 2004-05-19 | 2005-12-01 | Wyeth | Modulation of immunoglobulin production and atopic disorders |
CA2574848A1 (en) | 2004-08-05 | 2006-12-21 | Wyeth | Antagonizing interleukin-21 receptor activity |
GT200600148A (es) * | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis | |
WO2009100035A2 (en) | 2008-02-01 | 2009-08-13 | Wyeth | Interleukin-21 (il-21) and il-21 receptor (il-21r) modulation of regulatory t cells and forkhead box p3 (foxp3) |
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- 2004-03-12 EP EP09178337A patent/EP2184298A1/de not_active Withdrawn
- 2004-03-12 EP EP04720349A patent/EP1603949B9/de not_active Revoked
- 2004-03-12 AT AT04720349T patent/ATE456581T1/de not_active IP Right Cessation
- 2004-03-12 WO PCT/US2004/007444 patent/WO2004083249A2/en active Application Filing
- 2004-03-12 CN CN2010101657309A patent/CN102040662A/zh active Pending
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- 2004-03-12 DE DE602004025332T patent/DE602004025332D1/de not_active Expired - Lifetime
- 2004-03-12 ES ES04720349T patent/ES2340280T3/es not_active Expired - Lifetime
- 2004-03-15 CL CL200400534A patent/CL2004000534A1/es unknown
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- 2005-09-02 ZA ZA200507067A patent/ZA200507067B/xx unknown
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Also Published As
Publication number | Publication date |
---|---|
WO2004083249A2 (en) | 2004-09-30 |
CN102040662A (zh) | 2011-05-04 |
AU2004221876B2 (en) | 2011-05-26 |
ZA200507067B (en) | 2006-12-27 |
MXPA05009556A (es) | 2005-11-16 |
CN1777621A (zh) | 2006-05-24 |
EP1603949B9 (de) | 2011-02-02 |
JP4914209B2 (ja) | 2012-04-11 |
BRPI0408315A (pt) | 2006-03-07 |
AR043616A1 (es) | 2005-08-03 |
DE602004025332D1 (de) | 2010-03-18 |
CO5660297A2 (es) | 2006-07-31 |
CL2004000534A1 (es) | 2005-03-04 |
US20100297151A1 (en) | 2010-11-25 |
EP1603949B8 (de) | 2010-03-10 |
JP2007525159A (ja) | 2007-09-06 |
RU2005131852A (ru) | 2006-04-20 |
EP1603949B1 (de) | 2010-01-27 |
NO20054170L (no) | 2005-12-05 |
US8143385B2 (en) | 2012-03-27 |
EP2184298A1 (de) | 2010-05-12 |
KR20050119120A (ko) | 2005-12-20 |
ES2340280T3 (es) | 2010-06-01 |
EP1603949A2 (de) | 2005-12-14 |
US20040265960A1 (en) | 2004-12-30 |
US7495085B2 (en) | 2009-02-24 |
WO2004083249A3 (en) | 2004-12-09 |
AU2004221876A1 (en) | 2004-09-30 |
CA2518371A1 (en) | 2004-09-30 |
NO20054170D0 (no) | 2005-09-07 |
NZ542306A (en) | 2008-04-30 |
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