ATE396185T1 - Substituierte 4-alkyl- und 4- alkanoylpiperidinderivate und deren verwendung als neurokininantagonisten - Google Patents
Substituierte 4-alkyl- und 4- alkanoylpiperidinderivate und deren verwendung als neurokininantagonistenInfo
- Publication number
- ATE396185T1 ATE396185T1 AT05729797T AT05729797T ATE396185T1 AT E396185 T1 ATE396185 T1 AT E396185T1 AT 05729797 T AT05729797 T AT 05729797T AT 05729797 T AT05729797 T AT 05729797T AT E396185 T1 ATE396185 T1 AT E396185T1
- Authority
- AT
- Austria
- Prior art keywords
- alkanoylpiperidine
- neurokine
- antagonists
- derivatives
- substituted
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04101467 | 2004-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE396185T1 true ATE396185T1 (de) | 2008-06-15 |
Family
ID=34928945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05729797T ATE396185T1 (de) | 2004-04-08 | 2005-04-04 | Substituierte 4-alkyl- und 4- alkanoylpiperidinderivate und deren verwendung als neurokininantagonisten |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20070213346A1 (de) |
| EP (1) | EP1737838B1 (de) |
| JP (1) | JP2007532516A (de) |
| KR (1) | KR20070007347A (de) |
| CN (1) | CN1938291B (de) |
| AR (1) | AR048532A1 (de) |
| AT (1) | ATE396185T1 (de) |
| AU (1) | AU2005231986B2 (de) |
| BR (1) | BRPI0509720A (de) |
| CA (1) | CA2561967A1 (de) |
| DE (1) | DE602005007002D1 (de) |
| EA (1) | EA010312B1 (de) |
| ES (1) | ES2307169T3 (de) |
| IL (1) | IL178461A0 (de) |
| JO (1) | JO2525B1 (de) |
| MX (1) | MXPA06011683A (de) |
| MY (1) | MY142773A (de) |
| NO (1) | NO20065022L (de) |
| NZ (1) | NZ550098A (de) |
| PA (1) | PA8628901A1 (de) |
| TW (1) | TWI358298B (de) |
| WO (1) | WO2005097774A1 (de) |
| ZA (1) | ZA200608356B (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4769257B2 (ja) * | 2005-02-23 | 2011-09-07 | シェーリング コーポレイション | ケモカインレセプターのインヒビターとして有用なピペリジニルピペラジン誘導体 |
| TWI385169B (zh) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
| TW200841879A (en) | 2007-04-27 | 2008-11-01 | Eisai R&D Man Co Ltd | Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same |
| US8513287B2 (en) | 2007-12-27 | 2013-08-20 | Eisai R&D Management Co., Ltd. | Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same |
| US8895551B2 (en) | 2009-04-02 | 2014-11-25 | Shionogi & Co., Ltd. | Acrylamide compounds and the use thereof |
| EP2623101B1 (de) | 2009-04-02 | 2021-04-21 | Merck Patent GmbH | Piperidin- und Piperazinderivate als Autotaxinhemmer |
| WO2011051478A1 (en) * | 2009-10-30 | 2011-05-05 | Domain Therapeutics | Novel oxime derivatives and their use as allosteric modulators of metabotropic glutamate receptors |
| WO2015036412A1 (en) * | 2013-09-12 | 2015-03-19 | F. Hoffmann-La Roche Ag | Indol-carboxamide derivatives |
| HUE047732T2 (hu) | 2015-05-18 | 2020-05-28 | Nerre Therapeutics Ltd | NK-1/NK-3 receptor antagonista vértolulások kezeléséhez |
| PL3765024T3 (pl) | 2018-03-14 | 2024-08-05 | KaNDy Therapeutics Limited | <div>Nowa formulacja farmaceutyczna zawierająca podwójnych antagonistów receptora nk-1/nk-3</div> |
| ES2963356T3 (es) * | 2019-06-12 | 2024-03-26 | Nouryon Chemicals Int Bv | Método para aislar ácido carboxílico a partir de una corriente lateral acuosa |
| US12215074B2 (en) | 2019-06-12 | 2025-02-04 | Nouryon Chemicals International B.V. | Process for the production of peroxyesters |
| JP7336541B2 (ja) | 2019-06-12 | 2023-08-31 | ヌーリオン ケミカルズ インターナショナル ベスローテン フェノーツハップ | 過酸化ジアシルを生成するためのプロセス |
| EP3983370B1 (de) | 2019-06-12 | 2023-08-02 | Nouryon Chemicals International B.V. | Verfahren zur herstellung von diacylperoxiden |
| WO2020249690A1 (en) | 2019-06-12 | 2020-12-17 | Nouryon Chemicals International B.V. | Process for the production of diacyl peroxides |
| US12533358B1 (en) | 2025-05-14 | 2026-01-27 | Bayer Consumer Care Ag | Methods of treatment with elinzanetant |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ321575A (en) * | 1995-10-30 | 1999-05-28 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4- substituted piperazine derivatives |
| TW382017B (en) * | 1995-12-27 | 2000-02-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives |
| GB0025354D0 (en) * | 2000-10-17 | 2000-11-29 | Glaxo Group Ltd | Chemical compounds |
| US6642226B2 (en) * | 2001-02-06 | 2003-11-04 | Hoffman-La Roche Inc. | Substituted phenyl-piperidine methanone compounds |
| US7514424B2 (en) * | 2002-12-23 | 2009-04-07 | Janssen Pharmaceutica N.V. | Substituted 4-(4-piperidin-4-yl-piperazin-1-yl)-azepane derivatives and their use as neurokinin antagonists |
-
2005
- 2005-03-22 JO JO200534A patent/JO2525B1/en active
- 2005-04-04 BR BRPI0509720-7A patent/BRPI0509720A/pt not_active IP Right Cessation
- 2005-04-04 NZ NZ550098A patent/NZ550098A/en unknown
- 2005-04-04 ES ES05729797T patent/ES2307169T3/es not_active Expired - Lifetime
- 2005-04-04 MX MXPA06011683A patent/MXPA06011683A/es active IP Right Grant
- 2005-04-04 WO PCT/EP2005/051509 patent/WO2005097774A1/en not_active Ceased
- 2005-04-04 JP JP2007506775A patent/JP2007532516A/ja not_active Ceased
- 2005-04-04 CA CA002561967A patent/CA2561967A1/en not_active Abandoned
- 2005-04-04 AT AT05729797T patent/ATE396185T1/de active
- 2005-04-04 DE DE602005007002T patent/DE602005007002D1/de not_active Expired - Lifetime
- 2005-04-04 EP EP05729797A patent/EP1737838B1/de not_active Expired - Lifetime
- 2005-04-04 EA EA200601880A patent/EA010312B1/ru not_active IP Right Cessation
- 2005-04-04 AU AU2005231986A patent/AU2005231986B2/en not_active Ceased
- 2005-04-04 CN CN2005800108231A patent/CN1938291B/zh not_active Expired - Fee Related
- 2005-04-04 KR KR1020067021935A patent/KR20070007347A/ko not_active Ceased
- 2005-04-04 US US11/547,868 patent/US20070213346A1/en not_active Abandoned
- 2005-04-05 PA PA20058628901A patent/PA8628901A1/es unknown
- 2005-04-06 MY MYPI20051549A patent/MY142773A/en unknown
- 2005-04-07 TW TW094110941A patent/TWI358298B/zh not_active IP Right Cessation
- 2005-04-07 AR ARP050101376A patent/AR048532A1/es not_active Application Discontinuation
-
2006
- 2006-10-05 IL IL178461A patent/IL178461A0/en unknown
- 2006-10-06 ZA ZA200608356A patent/ZA200608356B/en unknown
- 2006-11-03 NO NO20065022A patent/NO20065022L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005007002D1 (de) | 2008-07-03 |
| US20070213346A1 (en) | 2007-09-13 |
| AU2005231986B2 (en) | 2011-02-24 |
| JP2007532516A (ja) | 2007-11-15 |
| EP1737838A1 (de) | 2007-01-03 |
| MY142773A (en) | 2010-12-31 |
| WO2005097774A1 (en) | 2005-10-20 |
| AR048532A1 (es) | 2006-05-03 |
| ZA200608356B (en) | 2008-07-30 |
| EA010312B1 (ru) | 2008-08-29 |
| IL178461A0 (en) | 2007-02-11 |
| NZ550098A (en) | 2009-10-30 |
| BRPI0509720A (pt) | 2007-09-25 |
| KR20070007347A (ko) | 2007-01-15 |
| PA8628901A1 (es) | 2006-09-08 |
| TWI358298B (en) | 2012-02-21 |
| NO20065022L (no) | 2006-11-03 |
| TW200603797A (en) | 2006-02-01 |
| ES2307169T3 (es) | 2008-11-16 |
| EA200601880A1 (ru) | 2007-02-27 |
| JO2525B1 (en) | 2010-03-17 |
| CA2561967A1 (en) | 2005-10-20 |
| MXPA06011683A (es) | 2006-12-14 |
| AU2005231986A1 (en) | 2005-10-20 |
| EP1737838B1 (de) | 2008-05-21 |
| CN1938291A (zh) | 2007-03-28 |
| CN1938291B (zh) | 2011-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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