ATE427748T1 - Pyridin-derivate und ihre verwendung als urotensin ii antagonisten - Google Patents

Pyridin-derivate und ihre verwendung als urotensin ii antagonisten

Info

Publication number
ATE427748T1
ATE427748T1 AT04765436T AT04765436T ATE427748T1 AT E427748 T1 ATE427748 T1 AT E427748T1 AT 04765436 T AT04765436 T AT 04765436T AT 04765436 T AT04765436 T AT 04765436T AT E427748 T1 ATE427748 T1 AT E427748T1
Authority
AT
Austria
Prior art keywords
urotensin
antagonists
pyridine derivatives
pyridine
derivatives
Prior art date
Application number
AT04765436T
Other languages
English (en)
Inventor
Boris Mathys
Ller Claus M
Michael Scherz
Thomas Weller
Martine Clozel
Jirg Velker
Daniel Bur
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE427748T1 publication Critical patent/ATE427748T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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    • A61P35/00—Antineoplastic agents
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
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    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • A61P7/06—Antianaemics
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/12—Antihypertensives

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
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  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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AT04765436T 2003-09-26 2004-09-21 Pyridin-derivate und ihre verwendung als urotensin ii antagonisten ATE427748T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP0310746 2003-09-26

Publications (1)

Publication Number Publication Date
ATE427748T1 true ATE427748T1 (de) 2009-04-15

Family

ID=34384524

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04765436T ATE427748T1 (de) 2003-09-26 2004-09-21 Pyridin-derivate und ihre verwendung als urotensin ii antagonisten

Country Status (18)

Country Link
US (1) US7750161B2 (de)
EP (1) EP1670470B1 (de)
JP (1) JP4851328B2 (de)
KR (1) KR20070014108A (de)
CN (1) CN1856305B (de)
AR (1) AR045949A1 (de)
AT (1) ATE427748T1 (de)
AU (1) AU2004275488A1 (de)
BR (1) BRPI0414777A (de)
CA (1) CA2540196C (de)
DE (1) DE602004020486D1 (de)
IL (1) IL174497A0 (de)
MX (1) MXPA06003264A (de)
NO (1) NO20061395L (de)
RU (1) RU2006113948A (de)
TW (1) TW200526630A (de)
WO (1) WO2005030209A1 (de)
ZA (1) ZA200602442B (de)

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CA2584342C (en) 2004-10-20 2013-04-30 The Regents Of The University Of California Improved inhibitors for the soluble epoxide hydrolase
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ZA200602442B (en) 2007-09-26
KR20070014108A (ko) 2007-01-31
MXPA06003264A (es) 2006-06-08
DE602004020486D1 (de) 2009-05-20
AR045949A1 (es) 2005-11-16
RU2006113948A (ru) 2007-11-10
WO2005030209A8 (en) 2006-05-11
CA2540196A1 (en) 2005-04-07
NO20061395L (no) 2006-06-22
CN1856305A (zh) 2006-11-01
EP1670470A1 (de) 2006-06-21
US20070043081A1 (en) 2007-02-22
TW200526630A (en) 2005-08-16
CN1856305B (zh) 2010-04-28
BRPI0414777A (pt) 2006-11-21
US7750161B2 (en) 2010-07-06
AU2004275488A1 (en) 2005-04-07
JP2007506692A (ja) 2007-03-22
WO2005030209A1 (en) 2005-04-07
IL174497A0 (en) 2006-08-01
JP4851328B2 (ja) 2012-01-11
EP1670470B1 (de) 2009-04-08
CA2540196C (en) 2012-03-20

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