DE602006019611D1 - Neues künstliches basenpaar und verwendung davon - Google Patents

Neues künstliches basenpaar und verwendung davon

Info

Publication number
DE602006019611D1
DE602006019611D1 DE602006019611T DE602006019611T DE602006019611D1 DE 602006019611 D1 DE602006019611 D1 DE 602006019611D1 DE 602006019611 T DE602006019611 T DE 602006019611T DE 602006019611 T DE602006019611 T DE 602006019611T DE 602006019611 D1 DE602006019611 D1 DE 602006019611D1
Authority
DE
Germany
Prior art keywords
artificial base
new artificial
base couple
couple
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006019611T
Other languages
English (en)
Inventor
Ichiro Hirao
Michiko Hirao
Shigeyuki Yokoyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN Institute of Physical and Chemical Research
Original Assignee
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN Institute of Physical and Chemical Research filed Critical RIKEN Institute of Physical and Chemical Research
Publication of DE602006019611D1 publication Critical patent/DE602006019611D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE602006019611T 2005-08-04 2006-08-04 Neues künstliches basenpaar und verwendung davon Active DE602006019611D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005226492 2005-08-04
JP2006182062A JP5649018B2 (ja) 2005-08-04 2006-06-30 新規人工塩基対及びその利用
PCT/JP2006/315479 WO2007015557A1 (ja) 2005-08-04 2006-08-04 新規人工塩基対及びその利用

Publications (1)

Publication Number Publication Date
DE602006019611D1 true DE602006019611D1 (de) 2011-02-24

Family

ID=37708834

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006019611T Active DE602006019611D1 (de) 2005-08-04 2006-08-04 Neues künstliches basenpaar und verwendung davon

Country Status (9)

Country Link
US (1) US8212014B2 (de)
EP (1) EP1921141B1 (de)
JP (1) JP5649018B2 (de)
KR (1) KR20080034019A (de)
CN (1) CN101268188B (de)
AU (1) AU2006276413A1 (de)
DE (1) DE602006019611D1 (de)
HK (1) HK1120292A1 (de)
WO (1) WO2007015557A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101404374B1 (ko) 2005-12-09 2014-06-09 도꾸리쯔교세이호징 리가가쿠 겐큐소 핵산의 복제방법 및 신규한 인공 염기쌍
US8715984B2 (en) 2008-02-07 2014-05-06 Riken Modified tRNA containing unnatural base and use thereof
KR101556426B1 (ko) * 2008-03-31 2015-10-02 탁시스 바이오 가부시키가이샤 고선택ㆍ고효율로 ｐｃｒ 증폭이 가능한 신규 ｄｎａ
EP2487180B1 (de) * 2009-10-06 2014-12-03 Riken Neue künstliche fluoreszierende basen
WO2011132801A1 (ja) 2010-04-21 2011-10-27 独立行政法人理化学研究所 消光性ならびに蛍光性の核酸塩基類似体とその応用
KR102031715B1 (ko) * 2011-11-18 2019-10-14 탁시스 바이오 가부시키가이샤 표적 단백질에 결합하는 핵산 단편
AU2014306271A1 (en) 2013-08-08 2016-03-24 The Scripps Research Institute A method for the site-specific enzymatic labelling of nucleic acids in vitro by incorporation of unnatural nucleotides
EP3943607A1 (de) 2014-04-09 2022-01-26 The Scripps Research Institute Import von unnatürlichen oder modifizierten nukleosid-triphosphaten in zellen mittels nukleinsäure-triphosphattransportern
US10760083B2 (en) * 2015-10-30 2020-09-01 Tagcyx Biotechnologies Inc. DNA aptamer that binds to vWF
WO2017106767A1 (en) 2015-12-18 2017-06-22 The Scripps Research Institute Production of unnatural nucleotides using a crispr/cas9 system
ES2929047T3 (es) 2016-06-24 2022-11-24 Scripps Research Inst Transportador de nucleósido trifosfato novedoso y usos del mismo
AR112756A1 (es) 2017-07-11 2019-12-11 Synthorx Inc Incorporación de nucleótidos no naturales, y su método
KR20200035092A (ko) 2017-08-03 2020-04-01 신톡스, 인크. 자가면역 질환의 치료를 위한 사이토카인 접합체
BR112020017016A2 (pt) 2018-02-26 2020-12-29 Synthorx, Inc. Conjugados da il-15 e usos dos mesmos
TW202045208A (zh) 2019-02-06 2020-12-16 美商欣爍克斯公司 Il-2結合物及其使用方法
AU2020291535A1 (en) 2019-06-14 2022-01-20 The Scripps Research Institute Reagents and methods for replication, transcription, and translation in semi-synthetic organisms
CN114736213B (zh) * 2022-04-01 2024-02-02 合肥华纳生物医药科技有限公司 一种羧基-四氯-荧光素的制备方法
CN115477578B (zh) * 2022-10-18 2024-04-26 中国人民解放军61699部队 一种壬酰氯的纯化方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7101992B1 (en) 1999-07-15 2006-09-05 Japan Science And Technology Agency Nucleic acid base pair
EP1544294B8 (de) 2002-07-17 2014-03-19 Riken Nukleoside und nukleotide mit neuen unnatürlichen basen und verwendung davon
JP2004324271A (ja) 2003-04-25 2004-11-18 Nippon Koatsu Concrete Kk オーガドリルの排土抑制装置
JP4956802B2 (ja) * 2003-09-10 2012-06-20 独立行政法人理化学研究所 非天然型塩基を有するヌクレオシド又はヌクレオチド及びその利用
JP2005226492A (ja) 2004-02-10 2005-08-25 Toyota Motor Corp ターボチャージャを備えた内燃機関
JP4628092B2 (ja) 2004-12-24 2011-02-09 富士機工株式会社 ステアリングコラム装置
KR101404374B1 (ko) * 2005-12-09 2014-06-09 도꾸리쯔교세이호징 리가가쿠 겐큐소 핵산의 복제방법 및 신규한 인공 염기쌍

Also Published As

Publication number Publication date
KR20080034019A (ko) 2008-04-17
EP1921141A1 (de) 2008-05-14
WO2007015557A1 (ja) 2007-02-08
US8212014B2 (en) 2012-07-03
JP5649018B2 (ja) 2015-01-07
JP2007061087A (ja) 2007-03-15
HK1120292A1 (en) 2009-03-27
CN101268188B (zh) 2012-05-09
US20100285598A1 (en) 2010-11-11
AU2006276413A1 (en) 2007-02-08
EP1921141B1 (de) 2011-01-12
EP1921141A4 (de) 2009-05-06
CN101268188A (zh) 2008-09-17

Similar Documents

Publication Publication Date Title
DE602006019611D1 (de) Neues künstliches basenpaar und verwendung davon
DE602005003186D1 (de) Fluorkopolymer und dessen Verwendung
ATE428710T1 (de) Substituierte phenylaminothiazole und ihre verwendung
DE602005036752T8 (de) Künstliche Bandscheibe
ATE432056T1 (de) Zervikale zwischenwirbelprothese
DE602006014562D1 (de) Knochenzement-zusammensetzung und herstellungsverfahren
ATE509596T1 (de) Zervikale zwischenwirbelprothesen
ATE493396T1 (de) Neue indazolcarboxamide und ihre verwendung
FR2870106B1 (fr) Implant intervertebral
ATE531712T1 (de) Substituierte aryloxazole und ihre verwendung
DE602005009200D1 (de) Quecksilberfreisetzende zusammensetzungen und herstellungsverfahren dafür
DE602006020061D1 (de) Mucin-glycoprotein und anwendung davon
DE602006015175D1 (de) Leuchtstoff und herstellungsverfahren dafür
ATE511507T1 (de) Piperidinylcarbonylpyrrolidine und deren verwendung als melanocortinagonisten
DE502005007536D1 (de) Alpha-aminomethyl-alkoxysilane mit hoher reaktivität und verbesserter stabilität
DE602006019004D1 (de) Bandscheibenprothese
DE502005002170D1 (de) Amphiphile polymerzusammensetzungen und ihre verwendung
DE602005009321D1 (de) Hinonen und 3-o-geschützten morphinondienolcarboxylaten
DE602007007792D1 (de) Zusammensetzung auf xanthoxylinbasis und kosmetische verwendung dafür
DE602005012674D1 (de) Nachweiselement und nachweisverfahren
ATE411817T1 (de) Benzothiazolformulierungen und ihre verwendung
DE602005001752D1 (de) Keramische Teilchen
AT508430A5 (de) Formbauteil und dessen verwendung
DE112005000887D2 (de) Zwischenwirbelimplantat
ATE413396T1 (de) Pyrazindicarbonsäureamide und ihre verwendung