ATE456559T1 - Piperazinderivate mit ccr1-rezeptor- antagonistischer wirkung - Google Patents

Piperazinderivate mit ccr1-rezeptor- antagonistischer wirkung

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Publication number
ATE456559T1
ATE456559T1 AT02772651T AT02772651T ATE456559T1 AT E456559 T1 ATE456559 T1 AT E456559T1 AT 02772651 T AT02772651 T AT 02772651T AT 02772651 T AT02772651 T AT 02772651T AT E456559 T1 ATE456559 T1 AT E456559T1
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AT
Austria
Prior art keywords
antagonistic effect
piperazine derivatives
receptor antagonistic
ccr1 receptor
ccr1
Prior art date
Application number
AT02772651T
Other languages
English (en)
Inventor
Laura BLUMBERG
Matthew Brown
Matthew Hayward
Christopher POSS
Gregory Lundquist
Andre Shavnya
Original Assignee
Pfizer Prod Inc
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Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
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Publication of ATE456559T1 publication Critical patent/ATE456559T1/de

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT02772651T 2001-10-22 2002-09-26 Piperazinderivate mit ccr1-rezeptor- antagonistischer wirkung ATE456559T1 (de)

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ES2337241T3 (es) 2010-04-22
UY27503A1 (es) 2003-06-30
CA2463272C (en) 2009-11-17
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PA8556901A1 (es) 2003-11-12
PE20030568A1 (es) 2003-07-07
HUP0401735A3 (en) 2005-06-28
BG108674A (en) 2005-04-30
CA2463272A1 (en) 2003-05-01
DK1438298T3 (da) 2010-04-12
ECSP045073A (es) 2004-05-28
HRP20040289A2 (en) 2004-10-31
IS7180A (is) 2004-03-11
NO20041631L (no) 2004-05-26
EP1438298A1 (de) 2004-07-21
SK1852004A3 (sk) 2005-03-04
KR20040047941A (ko) 2004-06-05
IL160974A0 (en) 2004-08-31
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US20040034034A1 (en) 2004-02-19
JP2005507923A (ja) 2005-03-24
US7098212B2 (en) 2006-08-29
HN2002000300A (es) 2003-10-17
HUP0401735A2 (hu) 2005-01-28
PL370548A1 (en) 2005-05-30
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EE200400088A (et) 2004-10-15
BR0213452A (pt) 2004-11-09
WO2003035627A1 (en) 2003-05-01
CN1575283A (zh) 2005-02-02
DE60235249D1 (de) 2010-03-18
EP1438298B1 (de) 2010-01-27
MXPA04002423A (es) 2004-05-31
CZ2004519A3 (cs) 2004-12-15
OA12670A (en) 2006-06-20
AR037742A1 (es) 2004-12-01
AP2004003008A0 (en) 2004-06-30
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