OA12670A - Piperazine derivatives with ccr1 receptor antagonist activity. - Google Patents

Piperazine derivatives with ccr1 receptor antagonist activity. Download PDF

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Publication number
OA12670A
OA12670A OA1200400110A OA1200400110A OA12670A OA 12670 A OA12670 A OA 12670A OA 1200400110 A OA1200400110 A OA 1200400110A OA 1200400110 A OA1200400110 A OA 1200400110A OA 12670 A OA12670 A OA 12670A
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OA
OAPI
Prior art keywords
alkyl
oxo
piperazin
benzyl
fluoro
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OA1200400110A
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English (en)
Inventor
Laura Cook Blumberg
Matthew Frank Brown
Matthew Merrill Hayward
Lundquist Gregory Dean Jr
Christopher Stanley Poss
Andre Shavnya
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Pfizer Prod Inc
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Publication of OA12670A publication Critical patent/OA12670A/en

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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OA1200400110A 2001-10-22 2002-09-26 Piperazine derivatives with ccr1 receptor antagonist activity. OA12670A (en)

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SK1852004A3 (sk) 2005-03-04
JP2005507923A (ja) 2005-03-24
ZA200402090B (en) 2005-05-23
PL370548A1 (en) 2005-05-30
HN2002000300A (es) 2003-10-17
HRP20040289A2 (en) 2004-10-31
CZ2004519A3 (cs) 2004-12-15
EP1438298A1 (de) 2004-07-21
PE20030568A1 (es) 2003-07-07
US7098212B2 (en) 2006-08-29
CA2463272A1 (en) 2003-05-01
KR20040047941A (ko) 2004-06-05
CN1575283A (zh) 2005-02-02
AR037742A1 (es) 2004-12-01
WO2003035627A1 (en) 2003-05-01
EA006243B1 (ru) 2005-10-27
TNSN04072A1 (fr) 2006-06-01
PA8556901A1 (es) 2003-11-12
MXPA04002423A (es) 2004-05-31
ECSP045073A (es) 2004-05-28
US20040034034A1 (en) 2004-02-19
IS7180A (is) 2004-03-11
AP2004003008A0 (en) 2004-06-30
EE200400088A (et) 2004-10-15
NO20041631L (no) 2004-05-26
UY27503A1 (es) 2003-06-30
HUP0401735A2 (hu) 2005-01-28
DK1438298T3 (da) 2010-04-12
EP1438298B1 (de) 2010-01-27
CA2463272C (en) 2009-11-17
EA200400466A1 (ru) 2004-08-26
BR0213452A (pt) 2004-11-09
HUP0401735A3 (en) 2005-06-28
IL160974A0 (en) 2004-08-31
BG108674A (en) 2005-04-30
MA27142A1 (fr) 2005-01-03
DE60235249D1 (de) 2010-03-18
ATE456559T1 (de) 2010-02-15

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