IS7180A - Píperasínafleiður með CCR1 viðtaka mótverkandi virkni - Google Patents

Píperasínafleiður með CCR1 viðtaka mótverkandi virkni

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Publication number
IS7180A
IS7180A IS7180A IS7180A IS7180A IS 7180 A IS7180 A IS 7180A IS 7180 A IS7180 A IS 7180A IS 7180 A IS7180 A IS 7180A IS 7180 A IS7180 A IS 7180A
Authority
IS
Iceland
Prior art keywords
piperazine derivatives
receptor antagonism
ccr1 receptor
ccr1
antagonism
Prior art date
Application number
IS7180A
Other languages
English (en)
Inventor
Cook Blumberg Laura
Frank Brown Matthew
Merrill Hayward Matthew
Stanley Poss Christopher
Dean Lundquist Gregory Jr.
Shavnya Andrei
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of IS7180A publication Critical patent/IS7180A/is

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • C07D213/64—One oxygen atom attached in position 2 or 6
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IS7180A 2001-10-22 2004-03-11 Píperasínafleiður með CCR1 viðtaka mótverkandi virkni IS7180A (is)

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US20040034034A1 (en) 2004-02-19
PA8556901A1 (es) 2003-11-12
EE200400088A (et) 2004-10-15
DE60235249D1 (de) 2010-03-18
HN2002000300A (es) 2003-10-17
BG108674A (en) 2005-04-30
WO2003035627A1 (en) 2003-05-01
CA2463272C (en) 2009-11-17
EA200400466A1 (ru) 2004-08-26
HRP20040289A2 (en) 2004-10-31
BR0213452A (pt) 2004-11-09
MA27142A1 (fr) 2005-01-03
JP2005507923A (ja) 2005-03-24
IL160974A0 (en) 2004-08-31
PL370548A1 (en) 2005-05-30
HUP0401735A3 (en) 2005-06-28
SK1852004A3 (sk) 2005-03-04
ATE456559T1 (de) 2010-02-15
CN1575283A (zh) 2005-02-02
CZ2004519A3 (cs) 2004-12-15
PE20030568A1 (es) 2003-07-07
ECSP045073A (es) 2004-05-28
OA12670A (en) 2006-06-20
UY27503A1 (es) 2003-06-30
EP1438298A1 (en) 2004-07-21
NO20041631L (no) 2004-05-26
CA2463272A1 (en) 2003-05-01
MXPA04002423A (es) 2004-05-31
EP1438298B1 (en) 2010-01-27
KR20040047941A (ko) 2004-06-05
AP2004003008A0 (en) 2004-06-30
US7098212B2 (en) 2006-08-29
ES2337241T3 (es) 2010-04-22
HUP0401735A2 (hu) 2005-01-28
DK1438298T3 (da) 2010-04-12
AR037742A1 (es) 2004-12-01
EA006243B1 (ru) 2005-10-27
ZA200402090B (en) 2005-05-23

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