ATE445622T1 - Verbessertes verfahren zur herstellung von cefixim - Google Patents

Verbessertes verfahren zur herstellung von cefixim

Info

Publication number
ATE445622T1
ATE445622T1 AT05732994T AT05732994T ATE445622T1 AT E445622 T1 ATE445622 T1 AT E445622T1 AT 05732994 T AT05732994 T AT 05732994T AT 05732994 T AT05732994 T AT 05732994T AT E445622 T1 ATE445622 T1 AT E445622T1
Authority
AT
Austria
Prior art keywords
cephem
vinyl
amino
adjust
carboxylic acid
Prior art date
Application number
AT05732994T
Other languages
English (en)
Inventor
Reddy Bandi Parthasaradhi
Reddy Raji
Reddy Kura Rathnakar
Nagabelli Murali
Reddy Muralidhara
Original Assignee
Hetero Drugs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hetero Drugs Ltd filed Critical Hetero Drugs Ltd
Application granted granted Critical
Publication of ATE445622T1 publication Critical patent/ATE445622T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
AT05732994T 2005-03-29 2005-03-29 Verbessertes verfahren zur herstellung von cefixim ATE445622T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2005/000094 WO2006103686A1 (en) 2005-03-29 2005-03-29 An improved process for the preparation of cefixime

Publications (1)

Publication Number Publication Date
ATE445622T1 true ATE445622T1 (de) 2009-10-15

Family

ID=37052982

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05732994T ATE445622T1 (de) 2005-03-29 2005-03-29 Verbessertes verfahren zur herstellung von cefixim

Country Status (7)

Country Link
US (1) US7705142B2 (de)
EP (1) EP1863822B1 (de)
AT (1) ATE445622T1 (de)
DE (1) DE602005017197D1 (de)
ES (1) ES2334685T3 (de)
PL (1) PL1863822T3 (de)
WO (1) WO2006103686A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7662955B2 (en) * 2003-03-20 2010-02-16 Orchid Chemicals And Pharmaceuticals Ltd. Process for the preparation of cefoxitin
DE602005012866D1 (de) * 2004-12-21 2009-04-02 Lupin Ltd Verfahren zur hestellung von cefixim
CN101506147B (zh) 2006-09-07 2012-03-21 霍夫曼-拉罗奇有限公司 用于制备snac（n-（8-[2-羟基苯甲酰基]-氨基）辛酸钠）的方法
CN101016305B (zh) * 2007-02-12 2010-05-26 河源市制药工程技术研究开发中心 一种头孢克肟的合成方法
CN101362733B (zh) * 2008-09-16 2012-07-25 山东金城医药化工股份有限公司 头孢克肟侧链酸活性酯的制备方法
CN101928292B (zh) * 2010-09-19 2013-03-13 苏州致君万庆药业有限公司 头孢呋辛酸的制备方法
CN103467495A (zh) * 2013-09-29 2013-12-25 天津理工大学 一种头孢克肟化合物的制备方法
WO2016142902A1 (en) * 2015-03-11 2016-09-15 Lupin Limited Cefixime with reduced surface area and high stability
CN105481848A (zh) * 2015-12-01 2016-04-13 重庆天地药业有限责任公司 一种头孢替坦活性酯及高纯度头孢替坦酸的制备方法
CN111171051B (zh) * 2020-03-05 2021-09-10 山西阳和医药技术有限公司 一种头孢克肟的制备方法
CN112110872B (zh) * 2020-09-16 2022-12-16 上海应用技术大学 一种头孢类活性酯中间体及其连续制备方法
CN112300198B (zh) * 2020-11-26 2022-04-22 浙江普洛得邦制药有限公司 一种头孢克肟及其酯的合成方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
CH688319A5 (fr) 1994-06-03 1997-07-31 Marcham Trading & Investment L Procédé pour la préparation du céfixime trihydraté.
AT404251B (de) 1996-08-14 1998-10-27 Biochemie Gmbh Neues kristallines salz von cefixim
AT404727B (de) 1997-01-16 1999-02-25 Biochemie Gmbh Kristallines salz von cefixim und verfahren zu dessen herstellung
TW538045B (en) 1997-01-16 2003-06-21 Biochemie Gmbh Process for purifying cefixime
PT102061B (pt) 1997-10-08 2000-06-30 J K Ind Ltd Processo de preparacao de um antibiotico cefalosporina geralmente activo-cefixime
PT102062B (pt) 1997-10-08 2000-08-31 J K Ind Ltd Processo de preparacao de um antibiotico cefalosporina oralmente activo-cefixime
AT405402B (de) * 1997-12-04 1999-08-25 Biochemie Gmbh Kristalline salze von 7-(2-(aminothiazol-4-yl)-2 -(tert.butoxycarbonylmethoxyimino)acetamido)- 3-vinyl-3-cephem-4-carbonsäure
AT406773B (de) * 1998-04-02 2000-08-25 Biochemie Gmbh Neues salz von 7-(2-(aminothiazol-4yl)-2-
AT411996B (de) * 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
US6388070B1 (en) 2001-01-05 2002-05-14 Orchid Chemicals & Pharmaceuticals Ltd. Thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds
GB0118764D0 (en) * 2001-08-01 2001-09-26 Biochemie Gmbh Organic compounds
US6800755B2 (en) 2002-10-24 2004-10-05 Orchid Chemicals And Pharmaceuticals Limited Process for the preparation of cefixime
US7662955B2 (en) * 2003-03-20 2010-02-16 Orchid Chemicals And Pharmaceuticals Ltd. Process for the preparation of cefoxitin
US20050059820A1 (en) * 2003-09-17 2005-03-17 Debashish Datta Method for manufacture of ceftriaxone sodium
EP1721602A1 (de) * 2005-05-11 2006-11-15 The Jordanian Pharmaceutical Manufacturing Co. Orales Wirkstoffverabreichungssystem mit gesteuerter Freigabe

Also Published As

Publication number Publication date
ES2334685T3 (es) 2010-03-15
PL1863822T3 (pl) 2010-03-31
EP1863822B1 (de) 2009-10-14
US7705142B2 (en) 2010-04-27
WO2006103686A1 (en) 2006-10-05
DE602005017197D1 (de) 2009-11-26
US20080242858A1 (en) 2008-10-02
EP1863822A1 (de) 2007-12-12

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