ATE425157T1 - Chemokin rezeptor bindenden heterozyklische verbindungen - Google Patents
Chemokin rezeptor bindenden heterozyklische verbindungenInfo
- Publication number
- ATE425157T1 ATE425157T1 AT01971574T AT01971574T ATE425157T1 AT E425157 T1 ATE425157 T1 AT E425157T1 AT 01971574 T AT01971574 T AT 01971574T AT 01971574 T AT01971574 T AT 01971574T AT E425157 T1 ATE425157 T1 AT E425157T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor binding
- heterocyclic compounds
- chemokine receptor
- binding heterocyclic
- ccr5
- Prior art date
Links
- 102000009410 Chemokine receptor Human genes 0.000 title abstract 2
- 108050000299 Chemokine receptor Proteins 0.000 title abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 102100035875 C-C chemokine receptor type 5 Human genes 0.000 abstract 1
- 101710149870 C-C chemokine receptor type 5 Proteins 0.000 abstract 1
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 abstract 1
- 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 abstract 1
- -1 Tertiary amine compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23289100P | 2000-09-15 | 2000-09-15 | |
| US23451000P | 2000-09-22 | 2000-09-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE425157T1 true ATE425157T1 (de) | 2009-03-15 |
Family
ID=26926422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01971574T ATE425157T1 (de) | 2000-09-15 | 2001-09-17 | Chemokin rezeptor bindenden heterozyklische verbindungen |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6864265B2 (de) |
| EP (1) | EP1317445B1 (de) |
| JP (1) | JP2004508422A (de) |
| KR (1) | KR20030029998A (de) |
| CN (1) | CN1457339A (de) |
| AT (1) | ATE425157T1 (de) |
| AU (2) | AU9156901A (de) |
| BR (1) | BR0113930A (de) |
| CA (1) | CA2419224A1 (de) |
| DE (1) | DE60137944D1 (de) |
| ES (1) | ES2325909T3 (de) |
| HK (1) | HK1052011A1 (de) |
| HU (1) | HUP0301093A2 (de) |
| IL (1) | IL154227A0 (de) |
| MX (1) | MXPA03002326A (de) |
| NO (1) | NO20031179D0 (de) |
| NZ (1) | NZ524420A (de) |
| PL (1) | PL360932A1 (de) |
| RU (1) | RU2289581C2 (de) |
| SG (1) | SG126007A1 (de) |
| TR (1) | TR200300322T2 (de) |
| WO (1) | WO2002022600A2 (de) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6864265B2 (en) * | 2000-09-15 | 2005-03-08 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| MXPA03002325A (es) * | 2000-09-15 | 2003-06-24 | Anormed Inc | Compuestos heterociclicos que se unen a receptor de quimiocina. |
| DK1317451T3 (da) | 2000-09-15 | 2006-12-18 | Anormed Inc | Kemokinreceptorbindende heterocykliske forbindelser |
| US7169750B2 (en) | 2001-07-31 | 2007-01-30 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
| JP5137288B2 (ja) | 2001-07-31 | 2013-02-06 | アノーメッド インコーポレイティド | 前駆／幹細胞を動員する方法 |
| CN1596255A (zh) * | 2001-12-21 | 2005-03-16 | 阿诺麦德股份有限公司 | 具有强效的与趋化因子受体结合的杂环化合物 |
| US7354932B2 (en) * | 2001-12-21 | 2008-04-08 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| AU2003261974A1 (en) | 2002-09-11 | 2004-04-30 | Kureha Chemical Industry Company, Limited | Amine compounds and use thereof |
| WO2004089360A1 (en) | 2003-04-02 | 2004-10-21 | Taigen Biotechnology | Polyamine compounds for treating chemokine receptor mediated diseases |
| US7504422B2 (en) | 2003-04-02 | 2009-03-17 | Taigen Biotechnology Co. Ltd. | Polyamine compounds |
| CA2520259A1 (en) | 2003-04-11 | 2004-10-28 | Anormed Inc. | Cxcr4 chemokine receptor binding compounds |
| JP4710606B2 (ja) * | 2003-04-18 | 2011-06-29 | 小野薬品工業株式会社 | スピロピペリジン化合物およびその医薬用途 |
| CA2517077C (en) | 2003-04-22 | 2013-03-12 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| US7501518B2 (en) | 2003-04-22 | 2009-03-10 | Genzyme Corporation | Methods of making 2,6-diaryl piperidine derivatives |
| CA2534649A1 (en) * | 2003-08-01 | 2005-02-10 | Genelabs Technologies, Inc. | Bicyclic imidazol derivatives against flaviviridae |
| US7498346B2 (en) | 2003-12-11 | 2009-03-03 | Genzyme Corporation | Chemokine receptor binding compounds |
| WO2005059107A2 (en) | 2003-12-11 | 2005-06-30 | Anormed Inc. | Chemokine receptor binding compounds |
| JP3977411B2 (ja) * | 2004-03-10 | 2007-09-19 | 株式会社クレハ | アミン系塩基性化合物とその用途 |
| WO2005090308A1 (en) * | 2004-03-15 | 2005-09-29 | Anormed, Inc. | Process for the synthesis of a cxcr4 antagonist |
| CA2561249A1 (en) * | 2004-03-31 | 2005-10-20 | Lexicon Genetics, Inc. | 2-aminomethylthiazole-5-carboxamides as protein kinase modulators |
| EP1796716A4 (de) * | 2004-08-13 | 2010-09-08 | Anormed Inc | Chemokin-kombinationen zur mobilisierung von vorläufer/stammzellen |
| AR050522A1 (es) * | 2004-08-16 | 2006-11-01 | Smithkline Beecham Corp | Derivados de bencimidazol como moduladores de la actividad de los receptores de quimioquina; composiciones farmaceuticas que los contienen; metodos para su preparacion y su uso en la fabricacion de medicamentos para el tratamiento contra infecciones por hiv |
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| JP5135795B2 (ja) * | 2004-08-27 | 2013-02-06 | 小野薬品工業株式会社 | 塩基性基を含有する化合物およびその用途 |
| MX2007002679A (es) * | 2004-09-02 | 2007-05-16 | Smithkline Beecham Corp | Compuestos quimicos. |
| WO2006036816A2 (en) * | 2004-09-24 | 2006-04-06 | Smithkline Beecham Corporation | Chemical compounds |
| TW200619206A (en) * | 2004-09-29 | 2006-06-16 | Anormed Inc | Chemokine-binding heterocyclic compound salts, and methods of use thereof |
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| US7501526B2 (en) | 2005-01-20 | 2009-03-10 | Taigen Biotechnology | Synthesis of polyamine compounds |
| US7538113B2 (en) | 2005-02-18 | 2009-05-26 | Wyeth | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7582634B2 (en) | 2005-02-18 | 2009-09-01 | Wyeth | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7534796B2 (en) | 2005-02-18 | 2009-05-19 | Wyeth | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7531542B2 (en) | 2005-05-18 | 2009-05-12 | Wyeth | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor |
| US7582636B2 (en) | 2005-05-26 | 2009-09-01 | Wyeth | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor |
| WO2006138350A2 (en) | 2005-06-15 | 2006-12-28 | Anormed Inc. | Chemokine receptor binding compounds |
| EP1904501A2 (de) * | 2005-07-11 | 2008-04-02 | Smithkline Beecham Corporation | Chemische verbindungen |
| CA2619828A1 (en) | 2005-08-19 | 2007-02-22 | Genzyme Corporation | Methods to enhance chemotherapy |
| EP1961744B1 (de) * | 2005-11-18 | 2013-04-17 | Ono Pharmaceutical Co., Ltd. | Verbindung mit basischen gruppen und deren verwendung |
| WO2007115232A2 (en) | 2006-03-30 | 2007-10-11 | Chemocentryx, Inc. | Cxcr4 modulators |
| US7807704B2 (en) * | 2006-03-30 | 2010-10-05 | Chemocentryx, Inc. | Bicyclic, nitrogen-containing compounds modulating CXCR4 and/or CCXCKR2 |
| JP5257068B2 (ja) * | 2006-05-16 | 2013-08-07 | 小野薬品工業株式会社 | 保護されていてもよい酸性基を含有する化合物およびその用途 |
| AU2007281090A1 (en) * | 2006-08-02 | 2008-02-07 | Genzyme Corporation | Combination therapy |
| MX2009001445A (es) * | 2006-08-07 | 2009-02-18 | Genzyme Corp | Terapia de combinacion. |
| WO2009036341A2 (en) * | 2007-09-14 | 2009-03-19 | The Regents Of The University Of Michigan | Compositions and methods relating to hiv protease inhibition |
| CA2728683C (en) * | 2008-07-02 | 2017-05-02 | F.Hoffmann-La Roche Ag | Novel phenylpyrazinones as kinase inhibitors |
| EP2337563B1 (de) * | 2008-09-08 | 2014-04-09 | The Board of Trustees of The Leland Stanford Junior University | Modulatoren der aldehyddehydrogenase-aktivität und anwendungsverfahren für diese |
| AU2011336397B2 (en) | 2010-12-03 | 2016-12-15 | Emory University | Chemokine CXCR4 receptor modulators and uses related thereto |
| CN102603683B (zh) * | 2012-02-10 | 2014-04-09 | 山东大学 | 一种呋喃类化合物及其制备方法与应用 |
| CN104478795A (zh) * | 2014-11-24 | 2015-04-01 | 苏州乔纳森新材料科技有限公司 | 一种2-氯烟醛的制备方法 |
| CA3026154A1 (en) | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| CN104945313A (zh) * | 2015-06-19 | 2015-09-30 | 洪帅金 | 一种2-甲基-3-溴吡啶的制备方法 |
| WO2017062581A1 (en) * | 2015-10-06 | 2017-04-13 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for modulating cftr |
| CN105198802A (zh) * | 2015-11-03 | 2015-12-30 | 江苏梦得电镀化学品有限公司 | 一种2-甲基-3-溴吡啶的制备方法 |
| ES2907489T3 (es) | 2015-12-14 | 2022-04-25 | X4 Pharmaceuticals Inc | Métodos para el tratamiento del cáncer |
| WO2017106332A1 (en) | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| HUE060517T2 (hu) | 2015-12-22 | 2023-03-28 | X4 Pharmaceuticals Inc | Immunhiányos betegség kezelésére szolgáló eljárások |
| WO2017177230A1 (en) | 2016-04-08 | 2017-10-12 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| WO2017223229A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
| CA3027500A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
| JP7054529B2 (ja) | 2016-06-21 | 2022-04-14 | エックス４ ファーマシューティカルズ， インコーポレイテッド | Ｃｘｃｒ４阻害剤およびその使用 |
| WO2018073248A1 (en) | 2016-10-17 | 2018-04-26 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Prognosis of demyelinating diseases patients and treatment thereof |
| US20210315909A1 (en) | 2018-07-11 | 2021-10-14 | Arrys Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| GB201910608D0 (en) | 2019-07-24 | 2019-09-04 | Enterprise Therapeutics Ltd | Compounds |
| JP2023517956A (ja) | 2020-03-10 | 2023-04-27 | エックス４ ファーマシューティカルズ， インコーポレイテッド | 好中球減少症を処置する方法 |
| US20230174518A1 (en) * | 2020-04-24 | 2023-06-08 | Taiho Pharmaceutical Co., Ltd. | Kras g12d protein inhibitors |
| CN112110853A (zh) * | 2020-09-23 | 2020-12-22 | 海南梵圣生物科技有限公司 | 一种合成3-羟基-2-吡啶甲酸及其衍生物的方法 |
| CN116375650B (zh) * | 2022-12-30 | 2025-08-05 | 浙江美诺华药物化学有限公司 | 一种替戈拉生中间体的制备方法 |
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|---|---|---|---|---|
| RU2024516C1 (ru) * | 1989-02-02 | 1994-12-15 | Яманути Фармасьютикал Ко., Лтд. | Способ получения производного тетрагидробензимидазола или его фармацевтически приемлемой соли |
| US6001826A (en) * | 1989-12-21 | 1999-12-14 | Anormed, Inc. | Chemical compounds |
| US5021409A (en) | 1989-12-21 | 1991-06-04 | Johnson Matthey Plc | Antiviral cyclic polyamines |
| GB9126677D0 (en) | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9400411D0 (en) | 1994-01-11 | 1994-03-09 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9511357D0 (en) * | 1995-06-06 | 1995-08-02 | Johnson Matthey Plc | Improved antiviral compounds |
| KR20010021700A (ko) | 1997-07-16 | 2001-03-15 | 베르너 훽스트, 지크프리트 포트호프 | 폴리글리시딜 스피로화합물 및 에폭시 수지에서의 그의 용도 |
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| WO2000042852A1 (en) * | 1999-01-25 | 2000-07-27 | Smithkline Beecham Corporation | Compounds and methods |
| AU3386500A (en) | 1999-03-02 | 2000-09-21 | Merck & Co., Inc. | 3-cyclopropyl and 3-cyclobutyl pyrrolidine modulators of chemokine receptor activity |
| AP1654A (en) * | 1999-03-24 | 2006-09-01 | Anormed Inc | Chemokine receptor binding heterocyclic compounds. |
| US6750348B1 (en) * | 1999-03-24 | 2004-06-15 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| US6864265B2 (en) * | 2000-09-15 | 2005-03-08 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| MXPA03002325A (es) * | 2000-09-15 | 2003-06-24 | Anormed Inc | Compuestos heterociclicos que se unen a receptor de quimiocina. |
-
2001
- 2001-09-17 US US09/957,682 patent/US6864265B2/en not_active Expired - Fee Related
- 2001-09-17 ES ES01971574T patent/ES2325909T3/es not_active Expired - Lifetime
- 2001-09-17 NZ NZ524420A patent/NZ524420A/en unknown
- 2001-09-17 AU AU9156901A patent/AU9156901A/xx active Pending
- 2001-09-17 CA CA002419224A patent/CA2419224A1/en not_active Abandoned
- 2001-09-17 IL IL15422701A patent/IL154227A0/xx unknown
- 2001-09-17 EP EP01971574A patent/EP1317445B1/de not_active Expired - Lifetime
- 2001-09-17 PL PL36093201A patent/PL360932A1/xx unknown
- 2001-09-17 DE DE60137944T patent/DE60137944D1/de not_active Expired - Lifetime
- 2001-09-17 MX MXPA03002326A patent/MXPA03002326A/es active IP Right Grant
- 2001-09-17 SG SG200502184A patent/SG126007A1/en unknown
- 2001-09-17 KR KR10-2003-7003710A patent/KR20030029998A/ko not_active Abandoned
- 2001-09-17 WO PCT/CA2001/001326 patent/WO2002022600A2/en not_active Ceased
- 2001-09-17 TR TR2003/00322T patent/TR200300322T2/xx unknown
- 2001-09-17 AT AT01971574T patent/ATE425157T1/de not_active IP Right Cessation
- 2001-09-17 AU AU2001291569A patent/AU2001291569B2/en not_active Ceased
- 2001-09-17 HK HK03104377.2A patent/HK1052011A1/zh unknown
- 2001-09-17 RU RU2003110577/04A patent/RU2289581C2/ru not_active IP Right Cessation
- 2001-09-17 CN CN01815627A patent/CN1457339A/zh active Pending
- 2001-09-17 JP JP2002526853A patent/JP2004508422A/ja active Pending
- 2001-09-17 BR BR0113930-4A patent/BR0113930A/pt not_active IP Right Cessation
- 2001-09-17 HU HU0301093A patent/HUP0301093A2/hu unknown
-
2003
- 2003-03-14 NO NO20031179A patent/NO20031179D0/no not_active Application Discontinuation
-
2004
- 2004-06-01 US US10/858,910 patent/US7084155B2/en not_active Expired - Fee Related
-
2006
- 2006-02-02 US US11/345,987 patent/US7396840B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| PL360932A1 (en) | 2004-09-20 |
| DE60137944D1 (de) | 2009-04-23 |
| HUP0301093A2 (hu) | 2003-09-29 |
| CN1457339A (zh) | 2003-11-19 |
| WO2002022600A2 (en) | 2002-03-21 |
| US20060128750A1 (en) | 2006-06-15 |
| TR200300322T2 (tr) | 2003-09-22 |
| US20040220207A1 (en) | 2004-11-04 |
| JP2004508422A (ja) | 2004-03-18 |
| RU2289581C2 (ru) | 2006-12-20 |
| NZ524420A (en) | 2005-04-29 |
| KR20030029998A (ko) | 2003-04-16 |
| HK1052011A1 (zh) | 2003-08-29 |
| MXPA03002326A (es) | 2003-06-06 |
| ES2325909T3 (es) | 2009-09-24 |
| NO20031179L (no) | 2003-03-14 |
| IL154227A0 (en) | 2003-07-31 |
| NO20031179D0 (no) | 2003-03-14 |
| EP1317445B1 (de) | 2009-03-11 |
| CA2419224A1 (en) | 2002-03-21 |
| US20030018046A1 (en) | 2003-01-23 |
| US7396840B2 (en) | 2008-07-08 |
| AU9156901A (en) | 2002-03-26 |
| WO2002022600A3 (en) | 2002-05-10 |
| BR0113930A (pt) | 2003-06-24 |
| EP1317445A2 (de) | 2003-06-11 |
| US6864265B2 (en) | 2005-03-08 |
| AU2001291569B2 (en) | 2007-07-26 |
| SG126007A1 (en) | 2006-10-30 |
| US7084155B2 (en) | 2006-08-01 |
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| Date | Code | Title | Description |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |