BR0113930A - Compostos heterocìclicos de ligação aos receptores de quimiocina - Google Patents

Compostos heterocìclicos de ligação aos receptores de quimiocina

Info

Publication number
BR0113930A
BR0113930A BR0113930-4A BR0113930A BR0113930A BR 0113930 A BR0113930 A BR 0113930A BR 0113930 A BR0113930 A BR 0113930A BR 0113930 A BR0113930 A BR 0113930A
Authority
BR
Brazil
Prior art keywords
heterocyclic
chemokine receptor
binding compounds
compounds
receptors
Prior art date
Application number
BR0113930-4A
Other languages
English (en)
Inventor
Gary Bridger
Renato Skerlj
Al Kaller
Curtis Harwig
David Bogucki
Trevor R Wilson
Jason Crawford
Ernest J Mceachern
Bem Atsma
Siqiao Nan
Yuanxi Zhou
Dominique Schols
Christopher Dennis Smith
Rosaria Maria Di Fluri
Original Assignee
Anormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anormed Inc filed Critical Anormed Inc
Publication of BR0113930A publication Critical patent/BR0113930A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Abstract

"COMPOSTOS HETEROCìCLICOS DE LIGAçãO AOS RECEPTORES DE QUIMIOCINA". A presente invenção refere-se a novos compostos que são úteis para marcar os receptores de quimiocina são descritos. Estes compostos são aminas terciárias complexas.
BR0113930-4A 2000-09-15 2001-09-17 Compostos heterocìclicos de ligação aos receptores de quimiocina BR0113930A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23289100P 2000-09-15 2000-09-15
US23451000P 2000-09-22 2000-09-22
PCT/CA2001/001326 WO2002022600A2 (en) 2000-09-15 2001-09-17 Chemokine receptor binding heterocyclic compounds

Publications (1)

Publication Number Publication Date
BR0113930A true BR0113930A (pt) 2003-06-24

Family

ID=26926422

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113930-4A BR0113930A (pt) 2000-09-15 2001-09-17 Compostos heterocìclicos de ligação aos receptores de quimiocina

Country Status (22)

Country Link
US (3) US6864265B2 (pt)
EP (1) EP1317445B1 (pt)
JP (1) JP2004508422A (pt)
KR (1) KR20030029998A (pt)
CN (1) CN1457339A (pt)
AT (1) ATE425157T1 (pt)
AU (2) AU9156901A (pt)
BR (1) BR0113930A (pt)
CA (1) CA2419224A1 (pt)
DE (1) DE60137944D1 (pt)
ES (1) ES2325909T3 (pt)
HK (1) HK1052011A1 (pt)
HU (1) HUP0301093A2 (pt)
IL (1) IL154227A0 (pt)
MX (1) MXPA03002326A (pt)
NO (1) NO20031179L (pt)
NZ (1) NZ524420A (pt)
PL (1) PL360932A1 (pt)
RU (1) RU2289581C2 (pt)
SG (1) SG126007A1 (pt)
TR (1) TR200300322T2 (pt)
WO (1) WO2002022600A2 (pt)

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Also Published As

Publication number Publication date
CA2419224A1 (en) 2002-03-21
NO20031179D0 (no) 2003-03-14
IL154227A0 (en) 2003-07-31
HUP0301093A2 (hu) 2003-09-29
EP1317445B1 (en) 2009-03-11
PL360932A1 (en) 2004-09-20
WO2002022600A3 (en) 2002-05-10
KR20030029998A (ko) 2003-04-16
TR200300322T2 (tr) 2003-09-22
US20030018046A1 (en) 2003-01-23
MXPA03002326A (es) 2003-06-06
NZ524420A (en) 2005-04-29
EP1317445A2 (en) 2003-06-11
CN1457339A (zh) 2003-11-19
US7396840B2 (en) 2008-07-08
WO2002022600A2 (en) 2002-03-21
NO20031179L (no) 2003-03-14
ATE425157T1 (de) 2009-03-15
HK1052011A1 (zh) 2003-08-29
ES2325909T3 (es) 2009-09-24
RU2289581C2 (ru) 2006-12-20
US7084155B2 (en) 2006-08-01
AU2001291569B2 (en) 2007-07-26
SG126007A1 (en) 2006-10-30
JP2004508422A (ja) 2004-03-18
US20040220207A1 (en) 2004-11-04
US6864265B2 (en) 2005-03-08
US20060128750A1 (en) 2006-06-15
AU9156901A (en) 2002-03-26
DE60137944D1 (de) 2009-04-23

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.