NO20031179L - Chemokin-reseptorbindende heterocykliske forbindelser - Google Patents
Chemokin-reseptorbindende heterocykliske forbindelserInfo
- Publication number
- NO20031179L NO20031179L NO20031179A NO20031179A NO20031179L NO 20031179 L NO20031179 L NO 20031179L NO 20031179 A NO20031179 A NO 20031179A NO 20031179 A NO20031179 A NO 20031179A NO 20031179 L NO20031179 L NO 20031179L
- Authority
- NO
- Norway
- Prior art keywords
- receptor binding
- heterocyclic compounds
- chemokine receptor
- binding heterocyclic
- ccr5
- Prior art date
Links
- 102000009410 Chemokine receptor Human genes 0.000 title abstract 2
- 108050000299 Chemokine receptor Proteins 0.000 title abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 102100035875 C-C chemokine receptor type 5 Human genes 0.000 abstract 1
- 101710149870 C-C chemokine receptor type 5 Proteins 0.000 abstract 1
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 abstract 1
- 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 abstract 1
- -1 Tertiary amine compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23289100P | 2000-09-15 | 2000-09-15 | |
| US23451000P | 2000-09-22 | 2000-09-22 | |
| PCT/CA2001/001326 WO2002022600A2 (en) | 2000-09-15 | 2001-09-17 | Chemokine receptor binding heterocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20031179D0 NO20031179D0 (no) | 2003-03-14 |
| NO20031179L true NO20031179L (no) | 2003-03-14 |
Family
ID=26926422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20031179A NO20031179L (no) | 2000-09-15 | 2003-03-14 | Chemokin-reseptorbindende heterocykliske forbindelser |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6864265B2 (no) |
| EP (1) | EP1317445B1 (no) |
| JP (1) | JP2004508422A (no) |
| KR (1) | KR20030029998A (no) |
| CN (1) | CN1457339A (no) |
| AT (1) | ATE425157T1 (no) |
| AU (2) | AU9156901A (no) |
| BR (1) | BR0113930A (no) |
| CA (1) | CA2419224A1 (no) |
| DE (1) | DE60137944D1 (no) |
| ES (1) | ES2325909T3 (no) |
| HK (1) | HK1052011A1 (no) |
| HU (1) | HUP0301093A2 (no) |
| IL (1) | IL154227A0 (no) |
| MX (1) | MXPA03002326A (no) |
| NO (1) | NO20031179L (no) |
| NZ (1) | NZ524420A (no) |
| PL (1) | PL360932A1 (no) |
| RU (1) | RU2289581C2 (no) |
| SG (1) | SG126007A1 (no) |
| TR (1) | TR200300322T2 (no) |
| WO (1) | WO2002022600A2 (no) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL154227A0 (en) | 2000-09-15 | 2003-07-31 | Anormed Inc | Chemokine receptor binding heterocyclic compounds |
| HUP0302960A3 (en) | 2000-09-15 | 2007-03-28 | Anormed Inc | Chemokine receptor binding heterocyclic compounds, their use and pharmaceutical compositions contining them |
| DE60137435D1 (de) * | 2000-09-15 | 2009-03-05 | Anormed Inc | Chemokin rezeptor bindenden heterozyklische verbindungen |
| US7169750B2 (en) | 2001-07-31 | 2007-01-30 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
| SI1411918T1 (sl) | 2001-07-31 | 2012-04-30 | Genzyme Global S A R L | Postopki za mobilizacijo progenitorskih/matičnih celic |
| BRPI0215050B8 (pt) * | 2001-12-21 | 2021-05-25 | Anormed Inc | compostos heterocíclicos de ligação a receptor de quimiocina, seus usos no tratamento de condições relacionadas aos receptores de quimiocinas, doenças inflamatórias, alérgicas e autoimunes, bem como composições farmacêuticas que os compreendem |
| US7354932B2 (en) * | 2001-12-21 | 2008-04-08 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| EP1550657A4 (en) * | 2002-09-11 | 2009-12-30 | Kureha Corp | AMINO COMPOUNDS AND THEIR USE |
| EP1608352B1 (en) | 2003-04-02 | 2009-12-30 | Taigen Biotechnology | Polyamine compounds for treating chemokine receptor mediated diseases |
| US7504422B2 (en) | 2003-04-02 | 2009-03-17 | Taigen Biotechnology Co. Ltd. | Polyamine compounds |
| EP1613613B1 (en) | 2003-04-11 | 2021-06-02 | Genzyme Corporation | Cxcr4 chemokine receptor binding compounds |
| JP4710606B2 (ja) * | 2003-04-18 | 2011-06-29 | 小野薬品工業株式会社 | スピロピペリジン化合物およびその医薬用途 |
| US7501518B2 (en) | 2003-04-22 | 2009-03-10 | Genzyme Corporation | Methods of making 2,6-diaryl piperidine derivatives |
| EP1615633B1 (en) | 2003-04-22 | 2012-08-15 | Genzyme Corporation | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| BRPI0413234A (pt) * | 2003-08-01 | 2006-10-03 | Genelabs Tech Inc | derivados de imidazola bicìclica contra flaviviridae |
| EP1708703A4 (en) | 2003-12-11 | 2008-04-09 | Anormed Inc | CHEMOKIN RECEPTOR BINDING COMPOUNDS |
| US7498346B2 (en) | 2003-12-11 | 2009-03-03 | Genzyme Corporation | Chemokine receptor binding compounds |
| CA2558600C (en) * | 2004-03-10 | 2013-07-09 | Kureha Corporation | A substituted-trialkyl amine compound with anti-viral activity based on antagonism against a chemokine receptor cxcr4 |
| CA2558389C (en) * | 2004-03-15 | 2013-10-08 | Anormed, Inc. | Process for the synthesis of a cxcr4 antagonist |
| JP2007531773A (ja) * | 2004-03-31 | 2007-11-08 | レキシコン・ジェネティクス・インコーポレーテッド | プロテインキナーゼ変調剤としての２−アミノメチルチアゾール−５−カルボキサミド |
| CN101094684A (zh) * | 2004-08-13 | 2007-12-26 | 阿诺麦德股份有限公司 | 用趋化因子的组合活化祖细胞/干细胞 |
| CA2577100A1 (en) * | 2004-08-16 | 2006-03-02 | Smithkline Beecham Corporation | Chemical compounds |
| RU2392923C2 (ru) * | 2004-08-19 | 2010-06-27 | Колгейт-Палмолив Компани | Увеличенная доставка масла из структурированных композиций поверхностно-активного вещества |
| EP1790639B1 (en) | 2004-08-27 | 2014-03-26 | Ono Pharmaceutical Co., Ltd. | Spirocyclic compounds and their use as cxcr4-antagonists |
| JP2008511669A (ja) * | 2004-09-02 | 2008-04-17 | スミスクライン ビーチャム コーポレーション | 化合物 |
| US20080171740A1 (en) * | 2004-09-24 | 2008-07-17 | Smithkline Beecham Corporation | Chemical Compounds |
| TW200619206A (en) * | 2004-09-29 | 2006-06-16 | Anormed Inc | Chemokine-binding heterocyclic compound salts, and methods of use thereof |
| AU2006204917A1 (en) * | 2005-01-14 | 2006-07-20 | Smithkline Beecham Corporation | Indole derivatives for treating viral infections |
| US7501526B2 (en) | 2005-01-20 | 2009-03-10 | Taigen Biotechnology | Synthesis of polyamine compounds |
| US7534796B2 (en) | 2005-02-18 | 2009-05-19 | Wyeth | Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7538113B2 (en) | 2005-02-18 | 2009-05-26 | Wyeth | 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7582634B2 (en) | 2005-02-18 | 2009-09-01 | Wyeth | 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor |
| US7531542B2 (en) | 2005-05-18 | 2009-05-12 | Wyeth | Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor |
| US7582636B2 (en) | 2005-05-26 | 2009-09-01 | Wyeth | Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor |
| US7790747B2 (en) | 2005-06-15 | 2010-09-07 | Genzyme Corporation | Chemokine receptor binding compounds |
| JP2009500451A (ja) * | 2005-07-11 | 2009-01-08 | スミスクライン ビーチャム コーポレーション | ピラノピリジン化合物 |
| EP1951046B1 (en) | 2005-08-19 | 2012-07-18 | Genzyme Corporation | Methods to enhance chemotherapy |
| WO2007058322A1 (ja) * | 2005-11-18 | 2007-05-24 | Ono Pharmaceutical Co., Ltd. | 塩基性基を含有する化合物およびその用途 |
| US7807704B2 (en) * | 2006-03-30 | 2010-10-05 | Chemocentryx, Inc. | Bicyclic, nitrogen-containing compounds modulating CXCR4 and/or CCXCKR2 |
| US7671069B2 (en) | 2006-03-30 | 2010-03-02 | Chemocentryx, Inc. | Tricyclic, heteroaromatic compounds modulating CXCR4 and/ or CXCR7 |
| WO2007132846A1 (ja) | 2006-05-16 | 2007-11-22 | Ono Pharmaceutical Co., Ltd. | 保護されていてもよい酸性基を含有する化合物およびその用途 |
| US20100003224A1 (en) * | 2006-08-02 | 2010-01-07 | Genzyme Corporation | Combination Therapy |
| BRPI0715393A2 (pt) * | 2006-08-07 | 2013-06-25 | Genzyme Corp | terapia de combinaÇço |
| US20110105477A1 (en) * | 2007-09-14 | 2011-05-05 | The Regents Of The University Of Michigan | Compositions and methods relating to hiv protease inhibition |
| AU2009265813B2 (en) * | 2008-07-02 | 2014-04-10 | F. Hoffmann-La Roche Ag | Novel phenylpyrazinones as kinase inhibitors |
| WO2010028175A1 (en) * | 2008-09-08 | 2010-03-11 | The Board Of Trustees Of The Leland Stanford Junior University | Modulators of aldehyde dehydrogenase activity and methods of use thereof |
| WO2012075362A2 (en) * | 2010-12-03 | 2012-06-07 | Emory University | Chemokine cxcr4 receptor modulators and used related thereto |
| CN102603683B (zh) * | 2012-02-10 | 2014-04-09 | 山东大学 | 一种呋喃类化合物及其制备方法与应用 |
| CN104478795A (zh) * | 2014-11-24 | 2015-04-01 | 苏州乔纳森新材料科技有限公司 | 一种2-氯烟醛的制备方法 |
| AU2016269839B2 (en) | 2015-06-03 | 2021-07-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| CN104945313A (zh) * | 2015-06-19 | 2015-09-30 | 洪帅金 | 一种2-甲基-3-溴吡啶的制备方法 |
| NZ741093A (en) * | 2015-10-06 | 2022-12-23 | Proteostasis Therapeutics Inc | Compounds, compositions, and methods for modulating cftr |
| CN105198802A (zh) * | 2015-11-03 | 2015-12-30 | 江苏梦得电镀化学品有限公司 | 一种2-甲基-3-溴吡啶的制备方法 |
| ES2907489T3 (es) | 2015-12-14 | 2022-04-25 | X4 Pharmaceuticals Inc | Métodos para el tratamiento del cáncer |
| US11357742B2 (en) | 2015-12-14 | 2022-06-14 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| ES2935834T3 (es) | 2015-12-22 | 2023-03-10 | X4 Pharmaceuticals Inc | Métodos para tratar enfermedad de inmunodeficiencia |
| US11337969B2 (en) | 2016-04-08 | 2022-05-24 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| JP7054529B2 (ja) | 2016-06-21 | 2022-04-14 | エックス４ ファーマシューティカルズ， インコーポレイテッド | Ｃｘｃｒ４阻害剤およびその使用 |
| US11332470B2 (en) | 2016-06-21 | 2022-05-17 | X4 Pharmaceuticals, Inc. | CXCR4 inhibitors and uses thereof |
| US10988465B2 (en) | 2016-06-21 | 2021-04-27 | X4 Pharmaceuticals, Inc. | CXCR4 inhibitors and uses thereof |
| WO2018073248A1 (en) | 2016-10-17 | 2018-04-26 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Prognosis of demyelinating diseases patients and treatment thereof |
| WO2020014465A1 (en) | 2018-07-11 | 2020-01-16 | Arrys Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| GB201910608D0 (en) * | 2019-07-24 | 2019-09-04 | Enterprise Therapeutics Ltd | Compounds |
| WO2021183650A1 (en) | 2020-03-10 | 2021-09-16 | X4 Pharmaceuticals, Inc. | Methods for treating neutropenia |
| US20230174518A1 (en) * | 2020-04-24 | 2023-06-08 | Taiho Pharmaceutical Co., Ltd. | Kras g12d protein inhibitors |
| CN112110853A (zh) * | 2020-09-23 | 2020-12-22 | 海南梵圣生物科技有限公司 | 一种合成3-羟基-2-吡啶甲酸及其衍生物的方法 |
| CN116375650B (zh) * | 2022-12-30 | 2025-08-05 | 浙江美诺华药物化学有限公司 | 一种替戈拉生中间体的制备方法 |
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| RU2024516C1 (ru) * | 1989-02-02 | 1994-12-15 | Яманути Фармасьютикал Ко., Лтд. | Способ получения производного тетрагидробензимидазола или его фармацевтически приемлемой соли |
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| GB9126677D0 (en) | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
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| JP2002535256A (ja) | 1999-01-25 | 2002-10-22 | スミスクライン・ビーチャム・コーポレイション | 化合物および方法 |
| WO2000051607A1 (en) * | 1999-03-02 | 2000-09-08 | Merck & Co., Inc. | 3-cyclopropyl and 3-cyclobutyl pyrrolidine modulators of chemokine receptor activity |
| US6750348B1 (en) * | 1999-03-24 | 2004-06-15 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| AP1654A (en) * | 1999-03-24 | 2006-09-01 | Anormed Inc | Chemokine receptor binding heterocyclic compounds. |
| IL154227A0 (en) * | 2000-09-15 | 2003-07-31 | Anormed Inc | Chemokine receptor binding heterocyclic compounds |
| DE60137435D1 (de) * | 2000-09-15 | 2009-03-05 | Anormed Inc | Chemokin rezeptor bindenden heterozyklische verbindungen |
-
2001
- 2001-09-17 IL IL15422701A patent/IL154227A0/xx unknown
- 2001-09-17 ES ES01971574T patent/ES2325909T3/es not_active Expired - Lifetime
- 2001-09-17 TR TR2003/00322T patent/TR200300322T2/xx unknown
- 2001-09-17 MX MXPA03002326A patent/MXPA03002326A/es active IP Right Grant
- 2001-09-17 HK HK03104377.2A patent/HK1052011A1/zh unknown
- 2001-09-17 EP EP01971574A patent/EP1317445B1/en not_active Expired - Lifetime
- 2001-09-17 JP JP2002526853A patent/JP2004508422A/ja active Pending
- 2001-09-17 RU RU2003110577/04A patent/RU2289581C2/ru not_active IP Right Cessation
- 2001-09-17 BR BR0113930-4A patent/BR0113930A/pt not_active IP Right Cessation
- 2001-09-17 SG SG200502184A patent/SG126007A1/en unknown
- 2001-09-17 WO PCT/CA2001/001326 patent/WO2002022600A2/en not_active Ceased
- 2001-09-17 HU HU0301093A patent/HUP0301093A2/hu unknown
- 2001-09-17 PL PL36093201A patent/PL360932A1/xx unknown
- 2001-09-17 DE DE60137944T patent/DE60137944D1/de not_active Expired - Lifetime
- 2001-09-17 NZ NZ524420A patent/NZ524420A/en unknown
- 2001-09-17 AU AU9156901A patent/AU9156901A/xx active Pending
- 2001-09-17 AT AT01971574T patent/ATE425157T1/de not_active IP Right Cessation
- 2001-09-17 CN CN01815627A patent/CN1457339A/zh active Pending
- 2001-09-17 KR KR10-2003-7003710A patent/KR20030029998A/ko not_active Abandoned
- 2001-09-17 CA CA002419224A patent/CA2419224A1/en not_active Abandoned
- 2001-09-17 US US09/957,682 patent/US6864265B2/en not_active Expired - Fee Related
- 2001-09-17 AU AU2001291569A patent/AU2001291569B2/en not_active Ceased
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2003
- 2003-03-14 NO NO20031179A patent/NO20031179L/no not_active Application Discontinuation
-
2004
- 2004-06-01 US US10/858,910 patent/US7084155B2/en not_active Expired - Fee Related
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2006
- 2006-02-02 US US11/345,987 patent/US7396840B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20060128750A1 (en) | 2006-06-15 |
| US6864265B2 (en) | 2005-03-08 |
| US20040220207A1 (en) | 2004-11-04 |
| BR0113930A (pt) | 2003-06-24 |
| JP2004508422A (ja) | 2004-03-18 |
| HUP0301093A2 (hu) | 2003-09-29 |
| EP1317445B1 (en) | 2009-03-11 |
| MXPA03002326A (es) | 2003-06-06 |
| PL360932A1 (en) | 2004-09-20 |
| NO20031179D0 (no) | 2003-03-14 |
| RU2289581C2 (ru) | 2006-12-20 |
| IL154227A0 (en) | 2003-07-31 |
| NZ524420A (en) | 2005-04-29 |
| US7396840B2 (en) | 2008-07-08 |
| AU9156901A (en) | 2002-03-26 |
| DE60137944D1 (de) | 2009-04-23 |
| HK1052011A1 (zh) | 2003-08-29 |
| EP1317445A2 (en) | 2003-06-11 |
| KR20030029998A (ko) | 2003-04-16 |
| SG126007A1 (en) | 2006-10-30 |
| ES2325909T3 (es) | 2009-09-24 |
| ATE425157T1 (de) | 2009-03-15 |
| WO2002022600A3 (en) | 2002-05-10 |
| CN1457339A (zh) | 2003-11-19 |
| TR200300322T2 (tr) | 2003-09-22 |
| AU2001291569B2 (en) | 2007-07-26 |
| CA2419224A1 (en) | 2002-03-21 |
| US20030018046A1 (en) | 2003-01-23 |
| WO2002022600A2 (en) | 2002-03-21 |
| US7084155B2 (en) | 2006-08-01 |
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