NO20031179L - Chemokin-reseptorbindende heterocykliske forbindelser - Google Patents

Chemokin-reseptorbindende heterocykliske forbindelser

Info

Publication number
NO20031179L
NO20031179L NO20031179A NO20031179A NO20031179L NO 20031179 L NO20031179 L NO 20031179L NO 20031179 A NO20031179 A NO 20031179A NO 20031179 A NO20031179 A NO 20031179A NO 20031179 L NO20031179 L NO 20031179L
Authority
NO
Norway
Prior art keywords
receptor binding
heterocyclic compounds
chemokine receptor
binding heterocyclic
ccr5
Prior art date
Application number
NO20031179A
Other languages
English (en)
Other versions
NO20031179D0 (no
Inventor
Gary Bridger
Renato Skerlj
Al Kaller
Curtis Harwig
David Boguki
Trevor R Wilson
Jason Crawford
Ernest J Mceachern
Berm Atsma
Siqiao Nan
Yuanxi Zhou
Dominique Schols
Christopher Smith
Maria Di Fluri
Original Assignee
Anormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anormed Inc filed Critical Anormed Inc
Publication of NO20031179D0 publication Critical patent/NO20031179D0/no
Publication of NO20031179L publication Critical patent/NO20031179L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
NO20031179A 2000-09-15 2003-03-14 Chemokin-reseptorbindende heterocykliske forbindelser NO20031179L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23289100P 2000-09-15 2000-09-15
US23451000P 2000-09-22 2000-09-22
PCT/CA2001/001326 WO2002022600A2 (en) 2000-09-15 2001-09-17 Chemokine receptor binding heterocyclic compounds

Publications (2)

Publication Number Publication Date
NO20031179D0 NO20031179D0 (no) 2003-03-14
NO20031179L true NO20031179L (no) 2003-03-14

Family

ID=26926422

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20031179A NO20031179L (no) 2000-09-15 2003-03-14 Chemokin-reseptorbindende heterocykliske forbindelser

Country Status (22)

Country Link
US (3) US6864265B2 (no)
EP (1) EP1317445B1 (no)
JP (1) JP2004508422A (no)
KR (1) KR20030029998A (no)
CN (1) CN1457339A (no)
AT (1) ATE425157T1 (no)
AU (2) AU9156901A (no)
BR (1) BR0113930A (no)
CA (1) CA2419224A1 (no)
DE (1) DE60137944D1 (no)
ES (1) ES2325909T3 (no)
HK (1) HK1052011A1 (no)
HU (1) HUP0301093A2 (no)
IL (1) IL154227A0 (no)
MX (1) MXPA03002326A (no)
NO (1) NO20031179L (no)
NZ (1) NZ524420A (no)
PL (1) PL360932A1 (no)
RU (1) RU2289581C2 (no)
SG (1) SG126007A1 (no)
TR (1) TR200300322T2 (no)
WO (1) WO2002022600A2 (no)

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US7550484B2 (en) 2003-04-22 2009-06-23 Genzyme Corporation Chemokine receptor binding heterocyclic compounds with enhanced efficacy
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EP1708703A4 (en) 2003-12-11 2008-04-09 Anormed Inc CHEMOKIN RECEPTOR BINDING COMPOUNDS
US7498346B2 (en) 2003-12-11 2009-03-03 Genzyme Corporation Chemokine receptor binding compounds
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CA2558389C (en) * 2004-03-15 2013-10-08 Anormed, Inc. Process for the synthesis of a cxcr4 antagonist
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BRPI0514487A (pt) * 2004-08-19 2008-06-17 Colgate Palmolive Co método de preparar uma composição, e, composição
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TW200619206A (en) * 2004-09-29 2006-06-16 Anormed Inc Chemokine-binding heterocyclic compound salts, and methods of use thereof
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EP1942890A4 (en) 2005-06-15 2009-08-26 Genzyme Corp CHEMOKINE RECEPTOR BINDING COMPOUNDS
JP2009500451A (ja) * 2005-07-11 2009-01-08 スミスクライン ビーチャム コーポレーション ピラノピリジン化合物
BRPI0615180A2 (pt) 2005-08-19 2011-05-03 Genzyme Corp método para intensificar a quimioterapia
ES2407115T3 (es) * 2005-11-18 2013-06-11 Ono Pharmaceutical Co., Ltd. Compuesto que contiene un grupo básico y uso del mismo
US7807704B2 (en) * 2006-03-30 2010-10-05 Chemocentryx, Inc. Bicyclic, nitrogen-containing compounds modulating CXCR4 and/or CCXCKR2
US7671069B2 (en) 2006-03-30 2010-03-02 Chemocentryx, Inc. Tricyclic, heteroaromatic compounds modulating CXCR4 and/ or CXCR7
JP5257068B2 (ja) 2006-05-16 2013-08-07 小野薬品工業株式会社 保護されていてもよい酸性基を含有する化合物およびその用途
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Also Published As

Publication number Publication date
CA2419224A1 (en) 2002-03-21
NO20031179D0 (no) 2003-03-14
IL154227A0 (en) 2003-07-31
HUP0301093A2 (hu) 2003-09-29
EP1317445B1 (en) 2009-03-11
BR0113930A (pt) 2003-06-24
PL360932A1 (en) 2004-09-20
WO2002022600A3 (en) 2002-05-10
KR20030029998A (ko) 2003-04-16
TR200300322T2 (tr) 2003-09-22
US20030018046A1 (en) 2003-01-23
MXPA03002326A (es) 2003-06-06
NZ524420A (en) 2005-04-29
EP1317445A2 (en) 2003-06-11
CN1457339A (zh) 2003-11-19
US7396840B2 (en) 2008-07-08
WO2002022600A2 (en) 2002-03-21
ATE425157T1 (de) 2009-03-15
HK1052011A1 (zh) 2003-08-29
ES2325909T3 (es) 2009-09-24
RU2289581C2 (ru) 2006-12-20
US7084155B2 (en) 2006-08-01
AU2001291569B2 (en) 2007-07-26
SG126007A1 (en) 2006-10-30
JP2004508422A (ja) 2004-03-18
US20040220207A1 (en) 2004-11-04
US6864265B2 (en) 2005-03-08
US20060128750A1 (en) 2006-06-15
AU9156901A (en) 2002-03-26
DE60137944D1 (de) 2009-04-23

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