NO20031179D0 - Chemokin-reseptorbindende heterocykliske forbindelser - Google Patents

Chemokin-reseptorbindende heterocykliske forbindelser

Info

Publication number
NO20031179D0
NO20031179D0 NO20031179A NO20031179A NO20031179D0 NO 20031179 D0 NO20031179 D0 NO 20031179D0 NO 20031179 A NO20031179 A NO 20031179A NO 20031179 A NO20031179 A NO 20031179A NO 20031179 D0 NO20031179 D0 NO 20031179D0
Authority
NO
Norway
Prior art keywords
receptor binding
heterocyclic compounds
chemokine receptor
binding heterocyclic
ccr5
Prior art date
Application number
NO20031179A
Other languages
English (en)
Norwegian (no)
Other versions
NO20031179L (no
Inventor
Gary Bridger
Renato Skerlj
Al Kaller
Curtis Harwig
David Boguki
Trevor R Wilson
Jason Crawford
Ernest J Mceachern
Berm Atsma
Siqiao Nan
Yuanxi Zhou
Dominique Schols
Christopher Smith
Maria Di Fluri
Original Assignee
Anormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anormed Inc filed Critical Anormed Inc
Publication of NO20031179L publication Critical patent/NO20031179L/no
Publication of NO20031179D0 publication Critical patent/NO20031179D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
NO20031179A 2000-09-15 2003-03-14 Chemokin-reseptorbindende heterocykliske forbindelser NO20031179D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23289100P 2000-09-15 2000-09-15
US23451000P 2000-09-22 2000-09-22
PCT/CA2001/001326 WO2002022600A2 (en) 2000-09-15 2001-09-17 Chemokine receptor binding heterocyclic compounds

Publications (2)

Publication Number Publication Date
NO20031179L NO20031179L (no) 2003-03-14
NO20031179D0 true NO20031179D0 (no) 2003-03-14

Family

ID=26926422

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20031179A NO20031179D0 (no) 2000-09-15 2003-03-14 Chemokin-reseptorbindende heterocykliske forbindelser

Country Status (22)

Country Link
US (3) US6864265B2 (de)
EP (1) EP1317445B1 (de)
JP (1) JP2004508422A (de)
KR (1) KR20030029998A (de)
CN (1) CN1457339A (de)
AT (1) ATE425157T1 (de)
AU (2) AU9156901A (de)
BR (1) BR0113930A (de)
CA (1) CA2419224A1 (de)
DE (1) DE60137944D1 (de)
ES (1) ES2325909T3 (de)
HK (1) HK1052011A1 (de)
HU (1) HUP0301093A2 (de)
IL (1) IL154227A0 (de)
MX (1) MXPA03002326A (de)
NO (1) NO20031179D0 (de)
NZ (1) NZ524420A (de)
PL (1) PL360932A1 (de)
RU (1) RU2289581C2 (de)
SG (1) SG126007A1 (de)
TR (1) TR200300322T2 (de)
WO (1) WO2002022600A2 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2269465T3 (es) 2000-09-15 2007-04-01 Anormed Inc Compuestos heterociclicos de union a los receptores de la quimioquina.
SG126007A1 (en) * 2000-09-15 2006-10-30 Anormed Inc Chemokine receptor binding hetrocyclic compounds
CA2419219A1 (en) * 2000-09-15 2002-03-21 Anormed Inc. Chemokine receptor binding heterocyclic compounds
US7169750B2 (en) 2001-07-31 2007-01-30 Anormed, Inc. Methods to mobilize progenitor/stem cells
US6987102B2 (en) 2001-07-31 2006-01-17 Anormed, Inc. Methods to mobilize progenitor/stem cells
US7354932B2 (en) * 2001-12-21 2008-04-08 Anormed, Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
CA2467718C (en) * 2001-12-21 2011-04-26 Anormed Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
CA2488785C (en) 2002-09-11 2012-07-03 Kureha Chemical Industry Company, Limited Amine compound and use thereof
EP1608352B1 (de) 2003-04-02 2009-12-30 Taigen Biotechnology Polyamin-verbindungen zur behandlung von chemokin-rezeptor-vermittelten krankheiten
US7504422B2 (en) 2003-04-02 2009-03-17 Taigen Biotechnology Co. Ltd. Polyamine compounds
CA2520259A1 (en) 2003-04-11 2004-10-28 Anormed Inc. Cxcr4 chemokine receptor binding compounds
WO2004092169A1 (ja) * 2003-04-18 2004-10-28 Ono Pharmaceutical Co., Ltd. スピロピペリジン化合物およびその医薬用途
US7501518B2 (en) 2003-04-22 2009-03-10 Genzyme Corporation Methods of making 2,6-diaryl piperidine derivatives
MXPA05011353A (es) 2003-04-22 2005-11-28 Anormed Inc Compuestos heterociclicos que se unen al receptor de quimiocina con eficacia mejorada.
AU2004261667A1 (en) * 2003-08-01 2005-02-10 Genelabs Technologies, Inc. Bicyclic imidazol derivatives against Flaviviridae
US7498346B2 (en) 2003-12-11 2009-03-03 Genzyme Corporation Chemokine receptor binding compounds
EP1708703A4 (de) 2003-12-11 2008-04-09 Anormed Inc Chemokin-rezeptor-bindende verbindungen
WO2005085209A1 (ja) * 2004-03-10 2005-09-15 Kureha Corporation アミン系塩基性化合物とその用途
JP4870660B2 (ja) * 2004-03-15 2012-02-08 アノーメッド インコーポレイティド Cxcr4アンタゴニストの合成プロセス
JP2007531773A (ja) * 2004-03-31 2007-11-08 レキシコン・ジェネティクス・インコーポレーテッド プロテインキナーゼ変調剤としての2−アミノメチルチアゾール−5−カルボキサミド
CA2577046A1 (en) * 2004-08-13 2006-02-23 Anormed Inc. Chemokine combinations to mobilize progenitor/stem cells
BRPI0514438A (pt) * 2004-08-16 2008-06-10 Smithkline Beecham Corp composto, composição farmacêutica, uso de um composto, método para o tratamento ou profilaxia de uma condição ou doença moduladas por um receptor de quimiocina, e, processo para a preparação do composto
KR101210126B1 (ko) * 2004-08-19 2012-12-07 콜게이트-파아므올리브캄파니 구조화된 계면활성제 배합물 유래의 증진된 오일 전달
JP5135795B2 (ja) * 2004-08-27 2013-02-06 小野薬品工業株式会社 塩基性基を含有する化合物およびその用途
MX2007002679A (es) * 2004-09-02 2007-05-16 Smithkline Beecham Corp Compuestos quimicos.
EP1793825A4 (de) * 2004-09-24 2009-12-09 Smithkline Beecham Corp Chemische verbindungen
TW200619206A (en) * 2004-09-29 2006-06-16 Anormed Inc Chemokine-binding heterocyclic compound salts, and methods of use thereof
US20060211698A1 (en) * 2005-01-14 2006-09-21 Genelabs, Inc. Bicyclic heteroaryl derivatives for treating viruses
US7501526B2 (en) 2005-01-20 2009-03-10 Taigen Biotechnology Synthesis of polyamine compounds
CA2612325A1 (en) 2005-06-15 2006-12-28 Anormed Inc. Chemokine receptor binding compounds
EP1904501A2 (de) * 2005-07-11 2008-04-02 Smithkline Beecham Corporation Chemische verbindungen
BRPI0615180A2 (pt) 2005-08-19 2011-05-03 Genzyme Corp método para intensificar a quimioterapia
PT1961744E (pt) 2005-11-18 2013-05-15 Ono Pharmaceutical Co Composto que contém um grupo básico e sua utilização
WO2007115232A2 (en) 2006-03-30 2007-10-11 Chemocentryx, Inc. Cxcr4 modulators
WO2007115231A2 (en) * 2006-03-30 2007-10-11 Chemocentryx, Inc. Cxcr4 modulators
WO2007132846A1 (ja) 2006-05-16 2007-11-22 Ono Pharmaceutical Co., Ltd. 保護されていてもよい酸性基を含有する化合物およびその用途
WO2008017025A2 (en) * 2006-08-02 2008-02-07 Genzyme Corporation Combination therapy
US20100178271A1 (en) * 2006-08-07 2010-07-15 Genzyme Corporation Combination Therapy
WO2009036341A2 (en) * 2007-09-14 2009-03-19 The Regents Of The University Of Michigan Compositions and methods relating to hiv protease inhibition
CN102083819B (zh) * 2008-07-02 2014-07-09 霍夫曼-拉罗奇有限公司 作为激酶抑制剂的新型苯基吡嗪酮
US8354435B2 (en) * 2008-09-08 2013-01-15 The Board Of Trustees Of The Leland Stanford Junior University Modulators of aldehyde dehydrogenase activity and methods of use thereof
ES2607604T3 (es) * 2010-12-03 2017-04-03 Emory University Moduladores del receptor CXCR4 de quimiocina y usos relacionados con los mismos
CN102603683B (zh) * 2012-02-10 2014-04-09 山东大学 一种呋喃类化合物及其制备方法与应用
CN104478795A (zh) * 2014-11-24 2015-04-01 苏州乔纳森新材料科技有限公司 一种2-氯烟醛的制备方法
EP3302710A4 (de) 2015-06-03 2019-02-20 The University of Queensland Mobilisierungsmittel und verwendung davon
CN104945313A (zh) * 2015-06-19 2015-09-30 洪帅金 一种2-甲基-3-溴吡啶的制备方法
AU2016336437B2 (en) * 2015-10-06 2020-06-18 Proteostasis Therapeutics, Inc. Compounds, compositions, and methods for modulating CFTR
CN105198802A (zh) * 2015-11-03 2015-12-30 江苏梦得电镀化学品有限公司 一种2-甲基-3-溴吡啶的制备方法
WO2017106328A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
CN109069486A (zh) 2015-12-14 2018-12-21 X4 制药有限公司 治疗癌症的方法
EP3393468B1 (de) 2015-12-22 2022-09-14 X4 Pharmaceuticals, Inc. Verfahren zur behandlung einer immunschwächekrankheit
WO2017177230A1 (en) 2016-04-08 2017-10-12 X4 Pharmaceuticals, Inc. Methods for treating cancer
WO2017223229A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
ES2870920T3 (es) 2016-06-21 2021-10-28 X4 Pharmaceuticals Inc Inhibidores de CXCR4 y usos de los mismos
JP6994767B2 (ja) 2016-06-21 2022-01-14 エックス4 ファーマシューティカルズ, インコーポレイテッド Cxcr4阻害剤およびその使用
WO2018073248A1 (en) 2016-10-17 2018-04-26 Icm (Institut Du Cerveau Et De La Moelle Épinière) Prognosis of demyelinating diseases patients and treatment thereof
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
GB201910608D0 (en) * 2019-07-24 2019-09-04 Enterprise Therapeutics Ltd Compounds
CN112110853A (zh) * 2020-09-23 2020-12-22 海南梵圣生物科技有限公司 一种合成3-羟基-2-吡啶甲酸及其衍生物的方法
CN116375650A (zh) * 2022-12-30 2023-07-04 浙江美诺华药物化学有限公司 一种替戈拉生中间体的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001826A (en) 1989-12-21 1999-12-14 Anormed, Inc. Chemical compounds
US5021409A (en) 1989-12-21 1991-06-04 Johnson Matthey Plc Antiviral cyclic polyamines
GB9126677D0 (en) 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
GB9400411D0 (en) 1994-01-11 1994-03-09 Johnson Matthey Plc Improvements in chemical compounds
GB9511357D0 (en) * 1995-06-06 1995-08-02 Johnson Matthey Plc Improved antiviral compounds
WO1999003851A1 (en) 1997-07-16 1999-01-28 Ciba Specialty Chemicals Holding Inc. Polyglycidyl spirocompounds and their use in epoxy resins
CA2319781A1 (en) * 1998-02-02 1999-08-05 Liping Wang Cyclic amine modulators of chemokine receptor activity
JPH11269146A (ja) * 1998-03-24 1999-10-05 Mitsui Chem Inc 分化誘導剤
WO2000042852A1 (en) * 1999-01-25 2000-07-27 Smithkline Beecham Corporation Compounds and methods
US6362201B1 (en) 1999-03-02 2002-03-26 Merck & Co., Inc. 3-cyclopropyl and 3-cyclobutyl pyrrolidine modulators of chemokine receptor activity
US6750348B1 (en) * 1999-03-24 2004-06-15 Anormed, Inc. Chemokine receptor binding heterocyclic compounds
IL145401A0 (en) * 1999-03-24 2002-06-30 Anormed Inc Chemokine receptor binding heterocyclic compounds
SG126007A1 (en) * 2000-09-15 2006-10-30 Anormed Inc Chemokine receptor binding hetrocyclic compounds
CA2419219A1 (en) * 2000-09-15 2002-03-21 Anormed Inc. Chemokine receptor binding heterocyclic compounds

Also Published As

Publication number Publication date
HUP0301093A2 (hu) 2003-09-29
WO2002022600A3 (en) 2002-05-10
US20060128750A1 (en) 2006-06-15
HK1052011A1 (zh) 2003-08-29
US6864265B2 (en) 2005-03-08
RU2289581C2 (ru) 2006-12-20
NZ524420A (en) 2005-04-29
EP1317445B1 (de) 2009-03-11
US7396840B2 (en) 2008-07-08
ATE425157T1 (de) 2009-03-15
BR0113930A (pt) 2003-06-24
DE60137944D1 (de) 2009-04-23
SG126007A1 (en) 2006-10-30
ES2325909T3 (es) 2009-09-24
CA2419224A1 (en) 2002-03-21
CN1457339A (zh) 2003-11-19
WO2002022600A2 (en) 2002-03-21
AU9156901A (en) 2002-03-26
KR20030029998A (ko) 2003-04-16
TR200300322T2 (tr) 2003-09-22
US20030018046A1 (en) 2003-01-23
IL154227A0 (en) 2003-07-31
NO20031179L (no) 2003-03-14
PL360932A1 (en) 2004-09-20
AU2001291569B2 (en) 2007-07-26
MXPA03002326A (es) 2003-06-06
US7084155B2 (en) 2006-08-01
JP2004508422A (ja) 2004-03-18
US20040220207A1 (en) 2004-11-04
EP1317445A2 (de) 2003-06-11

Similar Documents

Publication Publication Date Title
NO20031179D0 (no) Chemokin-reseptorbindende heterocykliske forbindelser
TR200102029T2 (tr) 1-Heterosiklil ikameli diarilaminler.
NO20031161D0 (no) Chemokin-reseptorbindende heterocykliske forbindelser
BRPI0415361A (pt) antagonistas do receptor muscarìnico de acetilcolina
UY27927A1 (es) Antagonistas del receptor muscarínico m3 de acetilcolina
EP1613613A4 (de) Cxcr4-chemokinrezeptor-bindende verbindungen
GB0130347D0 (en) Compounds
NO20050429D0 (no) Substituert kinolin-CCR5-reseptorantagonister
DE60039446D1 (de) Cyclische aminverbindung als ccr5 antagonist
BRPI0510170A (pt) antagonistas do receptor muscarìnico de acetilcolina
ECSP066486A (es) Antagonistas de receptores de acetilcolina muscarínicos ii
BRPI0506777A (pt) antagonistas do receptor muscarìnico da acetilcolina
BRPI0412716A (pt) antagonistas de receptor muscarìnico de acetilcolina
EP1244452A4 (de) Urotensin-ii rezeptorantagonisten
BRPI0412679A (pt) antagonistas de receptor muscarìnico de acetilcolina
TW200519108A (en) Muscarinic acetylcholine receptor antagonists
TR200200357T2 (tr) Yeni integrin reseptör antagonistleri
ATE418542T1 (de) Als ccr5-antagonisten verwendbare aryloxim- piperazine
ATE266722T1 (de) Zyklische peptidomimetische urokinaserezeptorantagonisten
ATE279923T1 (de) Urotensin-ii rezeptorantagonisten
WO2002047456A3 (en) Urotensin-ii receptor antagonists
BR0002142A (pt) Inibidores de quinase myti
DE60130684D1 (de) Substituierte pyrrolidine als ccr-3-rezeptorantagonisten
ES1055415U (es) Toallero.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application
FC2A Withdrawal, rejection or dismissal of laid open patent application