ATE419228T1 - Herstellung von fluoromethyl-2,2,2-trifluoro-1- (trifluoromethyl)ethylether - Google Patents

Herstellung von fluoromethyl-2,2,2-trifluoro-1- (trifluoromethyl)ethylether

Info

Publication number
ATE419228T1
ATE419228T1 AT01922664T AT01922664T ATE419228T1 AT E419228 T1 ATE419228 T1 AT E419228T1 AT 01922664 T AT01922664 T AT 01922664T AT 01922664 T AT01922664 T AT 01922664T AT E419228 T1 ATE419228 T1 AT E419228T1
Authority
AT
Austria
Prior art keywords
fluoromethyl
trifluoro
trifluoromethyl
production
ethyl ether
Prior art date
Application number
AT01922664T
Other languages
English (en)
Inventor
Ashot Khrimian
Barry Jones
Original Assignee
Halocarbon Prod Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Halocarbon Prod Corp filed Critical Halocarbon Prod Corp
Application granted granted Critical
Publication of ATE419228T1 publication Critical patent/ATE419228T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B7/00—Halogens; Halogen acids
    • C01B7/19—Fluorine; Hydrogen fluoride
    • C01B7/191—Hydrogen fluoride
    • C01B7/195—Separation; Purification
    • C01B7/196—Separation; Purification by distillation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/34—Separation; Purification; Stabilisation; Use of additives
    • C07C41/40—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
    • C07C41/42—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation by distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/12—Saturated ethers containing halogen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT01922664T 2000-03-16 2001-03-15 Herstellung von fluoromethyl-2,2,2-trifluoro-1- (trifluoromethyl)ethylether ATE419228T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/527,045 US6469219B1 (en) 2000-03-16 2000-03-16 Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether

Publications (1)

Publication Number Publication Date
ATE419228T1 true ATE419228T1 (de) 2009-01-15

Family

ID=24099874

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01922664T ATE419228T1 (de) 2000-03-16 2001-03-15 Herstellung von fluoromethyl-2,2,2-trifluoro-1- (trifluoromethyl)ethylether

Country Status (15)

Country Link
US (1) US6469219B1 (de)
EP (3) EP2272816A1 (de)
JP (4) JP4112862B2 (de)
KR (3) KR100685070B1 (de)
CN (2) CN100509735C (de)
AT (1) ATE419228T1 (de)
AU (1) AU2001249438A1 (de)
BR (1) BR0109376A (de)
CA (3) CA2403105C (de)
CZ (1) CZ304716B6 (de)
DE (2) DE08173108T1 (de)
ES (2) ES2319162T3 (de)
HU (1) HUP0300589A3 (de)
PL (1) PL202495B1 (de)
WO (1) WO2001068577A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6469219B1 (en) * 2000-03-16 2002-10-22 Halocarbon Products Corporation Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
BRPI0406766B8 (pt) * 2003-01-14 2021-05-25 Baxter Int processo para a recuperação de 1,1,1,3,3,3-hexafluoroisopropanol a partir de corrente de rejeitos de síntese de sevoflurano
PL380525A1 (pl) * 2004-01-05 2007-02-19 Halocarbon Products Corporation Chromatograficzna metoda analizy zarówno w sposobie wytwarzania sewofluranu, jak też w końcowym sewofluranie
JP5432454B2 (ja) * 2005-02-15 2014-03-05 ヘイロウカーボン プロダクツ コーポレイション フッ化水素からのデスフルランの分離／精製方法
ES2381573T3 (es) * 2005-08-04 2012-05-29 Halocarbon Products Corporation Purificación de fluorometil 1,1,1,3,3,3-hexafluoroisopropil éter (sevoflurano)
JP5315609B2 (ja) * 2006-06-05 2013-10-16 ダイキン工業株式会社 新規カルボン酸化合物、その用途及びその製造方法
JP5114880B2 (ja) * 2006-07-06 2013-01-09 ダイキン工業株式会社 新規α−フルオロメトキシカルボン酸エステル、該α−フルオロメトキシカルボン酸エステルの製造方法及びセボフルランの製造方法
JP5163064B2 (ja) 2007-11-13 2013-03-13 ダイキン工業株式会社 新規カルボン酸エステル、その用途及びその製造方法
US7732647B2 (en) * 2007-12-27 2010-06-08 Halocarbon Products Corporation Process for the purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)
US20090275785A1 (en) * 2008-05-01 2009-11-05 Barry Jones Distillation Method For The Purification Of Sevoflurane And The Maintenance Of Certain Equipment That May Be Used In The Distillation Process
CN101659603B (zh) 2008-08-27 2014-05-07 中化蓝天集团有限公司 一种制备氟甲基-1,1,1,3,3,3-六氟异丙基醚的方法
JP5434236B2 (ja) 2009-04-28 2014-03-05 セントラル硝子株式会社 フルオロメチルヘキサフルオロイソプロピルエーテルの製造方法
US9102604B1 (en) 2010-02-15 2015-08-11 Baxter International Inc. Methods for cleaning distilling columns
DE102011077681A1 (de) 2011-06-17 2012-12-20 Evonik Degussa Gmbh Verfahren zur Herstellung von 3-Cyano-3,5,5-trimethylcyclohexanon
US8729313B2 (en) 2011-08-15 2014-05-20 Baxter International Inc. Process for the manufacturing of sevoflurane
WO2021187369A1 (ja) 2020-03-19 2021-09-23 セントラル硝子株式会社 （ハイドロ）ハロカーボンの製造方法
CN113943214B (zh) * 2021-11-11 2023-12-19 福建海西联合药业有限公司 一种运用于七氟烷生产的工艺
CN120025236B (zh) * 2025-04-21 2025-06-27 江苏恒瑞医药股份有限公司 一种制备七氟烷及其中间体的方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2425752A (en) * 1944-09-15 1947-08-19 Phillips Petroleum Co Separation of hydrogen fluoride from water and organic contaminants by distillation and decantation
US2992276A (en) * 1959-05-20 1961-07-11 Du Pont Process for preparing polyfluoro alkyl compounds
US3911024A (en) 1966-12-08 1975-10-07 Louise S Croix Fluorinated isopropyl derivatives
US3683092A (en) * 1970-07-31 1972-08-08 Baxter Laboratories Inc Method of anesthesia
US3689571A (en) * 1970-07-31 1972-09-05 Baxter Laboratories Inc Fluorinated ether
US3773907A (en) * 1971-03-09 1973-11-20 Buss Ag Process for the production of pure concentrated hf from impure fluosilicic acid
US3897502A (en) 1971-10-22 1975-07-29 Airco Inc Process for making fluorinated ethers
USRE29084E (en) * 1974-04-17 1976-12-21 Universal Oil Products Company Separate recycle of regenerated acid and of isoparaffin from HF catalyst regeneration zone
US4469898A (en) * 1979-12-26 1984-09-04 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4314087A (en) * 1979-12-26 1982-02-02 Baxter Travenol Laboratories, Inc. Methods of synthesizing hexafluoroisopropanol from impure mixtures and synthesis of a fluoromethyl ether therefrom
US4250334A (en) * 1979-12-26 1981-02-10 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4874901A (en) 1988-05-06 1989-10-17 Boc, Inc. Process for the production of polyfluorinated ethers
US4874902A (en) 1988-05-20 1989-10-17 Boc, Inc. Method for the preparation of fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether
GB9124087D0 (en) * 1991-11-13 1992-01-02 Ici Plc Chemical process
EP0518506B1 (de) * 1991-06-14 1997-08-20 Imperial Chemical Industries Plc Herstellung von Bis(fluormethyl)äther und von Difluormethan
JPH0532568A (ja) * 1991-07-31 1993-02-09 Daikin Ind Ltd フツ化水素とジクロロフルオロメタンの混合物からフツ化水素を除去する方法
CA2068068A1 (en) * 1991-08-30 1993-03-01 James H. Mestepey Recovery of anhydrous hydrogen fluoride from depleted uranium
GB9126355D0 (en) * 1991-12-11 1992-02-12 Ici Plc Production of hydrofluorocarbons
GB9208769D0 (en) * 1992-04-23 1992-06-10 Ici Plc Production of bis (fluoromethyl) ether and difluoromethane
JP2865554B2 (ja) * 1994-04-08 1999-03-08 セントラル硝子株式会社 フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルのガスクロマトグラフ分析
GB9600072D0 (en) * 1996-01-04 1996-03-06 Ici Plc Process for the production of fluoromethylhexafluoroisopropylether
JP3240043B2 (ja) * 1996-01-23 2001-12-17 セントラル硝子株式会社 フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルの精製方法
EP0822172B2 (de) 1996-02-21 2004-10-06 Central Glass Company, Limited Verfahren zur herstellung von fluoromethyl-(1,1,1,3,3,3)-hexafluoroisopropylether
US6352677B1 (en) * 1996-06-04 2002-03-05 Alliedsignal, Inc. Process to produce commercial grade anhydrous hydrogen fluoride (AHF) and uranium oxide from the delfuorination of uranium hexafluoride (UF6)
GB9616879D0 (en) * 1996-08-10 1996-09-25 Ici Plc Removal of water from process streams
US5705710A (en) 1997-01-15 1998-01-06 University Of Iowa Research Foundation Process for the synthesis of hexafluoroisopropyl ethers
US5969193A (en) 1997-08-18 1999-10-19 Medeva Pharmaceuticals Pa, Inc. Method for the preparation of sevoflurane
US5886239A (en) 1997-11-21 1999-03-23 Baxter International Inc. Method of preparing monofluoromethyl ethers
US6469219B1 (en) * 2000-03-16 2002-10-22 Halocarbon Products Corporation Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether

Also Published As

Publication number Publication date
KR100685072B1 (ko) 2007-02-22
KR20050107528A (ko) 2005-11-11
JP2003530323A (ja) 2003-10-14
EP2036877A2 (de) 2009-03-18
KR20020082886A (ko) 2002-10-31
EP1268381B1 (de) 2008-12-31
DE08173108T1 (de) 2009-08-13
CA2403105C (en) 2010-02-16
JP2014005287A (ja) 2014-01-16
CN100509735C (zh) 2009-07-08
PL365368A1 (en) 2004-12-27
CN1430592A (zh) 2003-07-16
PL202495B1 (pl) 2009-06-30
JP4112862B2 (ja) 2008-07-02
DE60137206D1 (de) 2009-02-12
KR100698653B1 (ko) 2007-03-23
EP1268381A4 (de) 2004-10-20
KR20050105289A (ko) 2005-11-03
WO2001068577A1 (en) 2001-09-20
CN100515926C (zh) 2009-07-22
CA2403105A1 (en) 2001-09-20
ES2319162T3 (es) 2009-05-05
CA2689573C (en) 2012-05-22
CN1636864A (zh) 2005-07-13
HUP0300589A2 (hu) 2003-07-28
EP1268381A1 (de) 2003-01-02
EP2036877B1 (de) 2015-08-12
KR100685070B1 (ko) 2007-02-22
CZ20023069A3 (cs) 2003-05-14
EP2036877A3 (de) 2009-07-15
CA2691933A1 (en) 2001-09-20
AU2001249438A1 (en) 2001-09-24
CZ304716B6 (cs) 2014-09-10
EP2272816A1 (de) 2011-01-12
JP5711050B2 (ja) 2015-04-30
JP5086118B2 (ja) 2012-11-28
ES2320720T1 (es) 2009-05-28
CA2689573A1 (en) 2001-09-20
HUP0300589A3 (en) 2003-10-28
US6469219B1 (en) 2002-10-22
BR0109376A (pt) 2004-01-13
JP2008143915A (ja) 2008-06-26
JP2011207902A (ja) 2011-10-20

Similar Documents

Publication Publication Date Title
ATE419228T1 (de) Herstellung von fluoromethyl-2,2,2-trifluoro-1- (trifluoromethyl)ethylether
EP1401433A4 (de) Gehemmte konformationsanaloga als mittel gegen diabetes und adipositas und verfahren
DE69022075D1 (de) Handwerkzeugmaschine zur Herstellung von kreisabschnittförmigen Nuten.
AR066694A2 (es) Metodo para la preparacion de citalopram
ATE219040T1 (de) Verfahren zur herstellung von sevoflurane
BG105692A (en) Method for the preparation of 5-cyanophthalide
EP1349693A4 (de) Elektrochemisches bearbeiten zur herstellung von nuten
ATE157075T1 (de) Herstellung von bis(fluormethyl)äther und von difluormethan
DE69915110D1 (de) Verfahren zur herstellung von arylethern
ATE339427T1 (de) Herstellung von sekundären aminoisobutylalkoxysilanen
DK1204659T3 (da) Serotonerge benzofuraner
DE60136463D1 (de) Verfahren zur herstellung von fluorierten acyl fluoriden und fluorierten vinylethern
ATE1625T1 (de) Isoxazolylcarbonsaeureanilide, ihre herstellung, diese enthaltende fungizide mittel und verfahren zur bekaempfung von pilzen.
DE50111886D1 (de) Verfahren zur Herstellung von Fluor enthaltenden Benzaldehyden
DK0812847T3 (da) Fremgangsmåde til fremstilling af 5-brom-2-fluorbenzenboronsyre
DE60107191D1 (de) Herstellung von 2-Hydrocarbyl-2-Adamantylacrylaten
NO980371L (no) Framgangsmåte for framstilling av en lösning av N-metylmorfolin-N-oksid i vann
BR0100131A (pt) Processo para misturação de um gás e um lìquido dentro de um recipiente fechado possuindo um espaço de gás superior, e, aparelhagem para misturação de um gás e um lìquido durante a operação de misturação
ES2121204T3 (es) Preparacion de fluoro-nucleosidos e intermedios para su uso en ella.
DE60317626D1 (de) Verfahren zur herstellung von 2,5-bis(trifluormethyl)nitrobenzol
DE69008036D1 (de) Verfahren zur Herstellung von aromatischen Ethern.
ATE257814T1 (de) Verfahren zur abtrennung von fluorwasserstoff aus seinen mischungen mit 1,1,1,3,3-pentafluorbutan und verfahren zur herstellung von pentafluorbutan
PT1307440E (pt) 1,3-dioxolanos dissubstituidos em 2,2 como agentes antitussicos
DE59501234D1 (de) Verfahren zur Herstellung von 2-Nitrobenzaldehyden
NO20004636L (no) FremgangsmÕte for separering av difosfindiastereoisomerer

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1268381

Country of ref document: EP

REN Ceased due to non-payment of the annual fee