ATE394103T1 - Verwendung von rosuvastatin (zd-4522) zur behandlung von heterozygoter familiärer hypercholesterolämie - Google Patents
Verwendung von rosuvastatin (zd-4522) zur behandlung von heterozygoter familiärer hypercholesterolämieInfo
- Publication number
- ATE394103T1 ATE394103T1 AT01982623T AT01982623T ATE394103T1 AT E394103 T1 ATE394103 T1 AT E394103T1 AT 01982623 T AT01982623 T AT 01982623T AT 01982623 T AT01982623 T AT 01982623T AT E394103 T1 ATE394103 T1 AT E394103T1
- Authority
- AT
- Austria
- Prior art keywords
- heterozygot
- rosuvastatin
- treatment
- familiar hypercholesterolemia
- hypercholesterolemia
- Prior art date
Links
- BPRHUIZQVSMCRT-VEUZHWNKSA-N rosuvastatin Chemical compound CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O BPRHUIZQVSMCRT-VEUZHWNKSA-N 0.000 title 2
- 208000035150 Hypercholesterolemia Diseases 0.000 title 1
- 229960000672 rosuvastatin Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0028429.9A GB0028429D0 (en) | 2000-11-22 | 2000-11-22 | Therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE394103T1 true ATE394103T1 (de) | 2008-05-15 |
Family
ID=9903629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01982623T ATE394103T1 (de) | 2000-11-22 | 2001-11-16 | Verwendung von rosuvastatin (zd-4522) zur behandlung von heterozygoter familiärer hypercholesterolämie |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6858618B2 (https=) |
| EP (1) | EP1339409B1 (https=) |
| JP (2) | JP5062940B2 (https=) |
| KR (1) | KR100815042B1 (https=) |
| CN (1) | CN1268339C (https=) |
| AR (1) | AR031766A1 (https=) |
| AT (1) | ATE394103T1 (https=) |
| AU (2) | AU2002214165B9 (https=) |
| BG (1) | BG66009B1 (https=) |
| BR (1) | BR0115511A (https=) |
| CA (1) | CA2429263C (https=) |
| CY (1) | CY1110428T1 (https=) |
| CZ (1) | CZ301583B6 (https=) |
| DE (1) | DE60133921D1 (https=) |
| DK (1) | DK1339409T3 (https=) |
| EE (1) | EE05507B1 (https=) |
| ES (1) | ES2305118T3 (https=) |
| GB (1) | GB0028429D0 (https=) |
| HU (1) | HUP0301380A3 (https=) |
| IL (2) | IL155919A0 (https=) |
| IS (1) | IS6819A (https=) |
| MX (1) | MXPA03004336A (https=) |
| MY (1) | MY134902A (https=) |
| NO (1) | NO326245B1 (https=) |
| NZ (1) | NZ525754A (https=) |
| PL (1) | PL365386A1 (https=) |
| PT (1) | PT1339409E (https=) |
| RU (1) | RU2294744C2 (https=) |
| SI (1) | SI1339409T1 (https=) |
| SK (1) | SK6212003A3 (https=) |
| TW (1) | TWI238720B (https=) |
| UA (1) | UA75614C2 (https=) |
| WO (1) | WO2002041895A1 (https=) |
| ZA (1) | ZA200303636B (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0003305D0 (en) | 2000-02-15 | 2000-04-05 | Zeneca Ltd | Pyrimidine derivatives |
| EA014685B1 (ru) | 2003-04-25 | 2010-12-30 | Джилид Сайэнс, Инк. | Фосфонатсодержащие антивирусные соединения (варианты) и фармацевтическая композиция на их основе |
| US7452901B2 (en) * | 2003-04-25 | 2008-11-18 | Gilead Sciences, Inc. | Anti-cancer phosphonate analogs |
| KR20060022647A (ko) * | 2003-04-25 | 2006-03-10 | 길리애드 사이언시즈, 인코포레이티드 | 키나아제 억제 포스포네이트 유사체 |
| US7407965B2 (en) * | 2003-04-25 | 2008-08-05 | Gilead Sciences, Inc. | Phosphonate analogs for treating metabolic diseases |
| US20050261237A1 (en) * | 2003-04-25 | 2005-11-24 | Boojamra Constantine G | Nucleoside phosphonate analogs |
| US7470724B2 (en) * | 2003-04-25 | 2008-12-30 | Gilead Sciences, Inc. | Phosphonate compounds having immuno-modulatory activity |
| US20090247488A1 (en) * | 2003-04-25 | 2009-10-01 | Carina Cannizzaro | Anti-inflammatory phosphonate compounds |
| CA2537271A1 (en) * | 2003-08-28 | 2005-03-17 | Teva Pharmaceutical Industries, Ltd. | Process for preparation of rosuvastatin calcium |
| GB0322552D0 (en) | 2003-09-26 | 2003-10-29 | Astrazeneca Uk Ltd | Therapeutic treatment |
| WO2005044308A1 (en) * | 2003-10-24 | 2005-05-19 | Gilead Sciences, Inc. | Phosphonate analogs of antimetabolites |
| CA2546701C (en) | 2003-11-24 | 2010-07-27 | Teva Pharmaceutical Industries Ltd. | Crystalline ammonium salts of rosuvastatin |
| CN1894221B (zh) * | 2003-12-02 | 2012-08-08 | 特瓦制药工业有限公司 | 用于表征罗苏伐他汀的参照标准品 |
| US7851624B2 (en) * | 2003-12-24 | 2010-12-14 | Teva Pharamaceutical Industries Ltd. | Triol form of rosuvastatin and synthesis of rosuvastatin |
| US20070179166A1 (en) * | 2003-12-24 | 2007-08-02 | Valerie Niddam-Hildesheim | Process for preparation of statins with high syn to anti ratio |
| CA2567963A1 (en) * | 2004-05-26 | 2005-12-08 | Kgk Synergize Inc. | Functional foods comprising flavonoids and tocotrienols and methods thereof |
| JP2007508379A (ja) * | 2004-07-13 | 2007-04-05 | テバ ファーマシューティカル インダストリーズ リミティド | Ｔｅｍｐｏ媒介型酸化段階を包含するロスバスタチンの調製方法 |
| AU2005330489B2 (en) | 2004-07-27 | 2011-08-25 | Gilead Sciences, Inc. | Nucleoside phosphonate conjugates as anti HIV agents |
| US20070167625A1 (en) * | 2005-02-22 | 2007-07-19 | Anna Balanov | Preparation of rosuvastatin |
| US7612203B2 (en) * | 2005-02-22 | 2009-11-03 | Teva Pharmaceutical Industries Ltd. | Rosuvastatin and salts thereof free of rosuvastatin alkylether and a process for the preparation thereof |
| US20070037979A1 (en) * | 2005-02-22 | 2007-02-15 | Valerie Niddam-Hildesheim | Preparation of rosuvastatin |
| KR20070062996A (ko) * | 2005-08-16 | 2007-06-18 | 테바 파마슈티컬 인더스트리즈 리미티드 | 결정성 로수바스타틴 중간체 |
| US8383614B2 (en) * | 2008-01-31 | 2013-02-26 | The Trustees Of The University Of Pennsylvania | Hypercholestrolemia and tendinous injuries |
| US9427437B2 (en) | 2008-01-31 | 2016-08-30 | The Trustees Of The University Of Pennsylvania | Hypercholesterolemia and tendinous injuries |
| EP2298745B1 (en) | 2008-05-27 | 2014-09-03 | Changzhou Pharmaceutical Factory | Preparation method of rosuvastatin calcium and its intermediates |
| US8658617B2 (en) | 2008-07-08 | 2014-02-25 | Gilead Sciences, Inc. | Salts of HIV inhibitor compounds |
| AR092872A1 (es) | 2012-09-17 | 2015-05-06 | Madrigal Pharmaceuticals Inc | Metodo para sintetizar analogos de la hormona tiroidea y polimorfos de los mismos |
| US9132117B2 (en) | 2013-06-17 | 2015-09-15 | Kgk Synergize, Inc | Compositions and methods for glycemic control of subjects with impaired fasting glucose |
| US10600502B2 (en) | 2016-12-20 | 2020-03-24 | Astrazeneca Uk Ltd. | Systems and methods for dispensing a statin medication over the counter |
| SI3661937T1 (sl) | 2017-08-01 | 2021-11-30 | Gilead Sciences, Inc. | Kristalinične oblike etil((S)-((((2R,5R)-5-(6-amino-9H-purin-9-IL)-4- fluoro-2,5-dihidrofuran-2-IL)oksi)metil)(fenoksi)fosforil)-L-alaninata (GS-9131) za zdravljenje virusnih okužb |
| WO2020243134A1 (en) | 2019-05-27 | 2020-12-03 | Immatics US, Inc. | Viral vectors and their use in adoptive cellular therapy |
| DE102020111571A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| US20220008519A1 (en) | 2020-07-09 | 2022-01-13 | Costa Rican Social Security Fund / Caja Costarricense de Seguro Social (CCSS) | Treatment of severe acute respiratory syndrome-related coronavirus infection with klotho |
| US20220056411A1 (en) | 2020-08-21 | 2022-02-24 | Immatics US, Inc. | Methods for isolating cd8+ selected t cells |
| KR20230142523A (ko) * | 2021-02-01 | 2023-10-11 | 마드리갈 파마슈티칼스, 인크. | 간 장애 또는 지질 장애의 치료를 위한 로수바스타틴 및 레스메티롬의 치료용 조합 |
| US12377104B1 (en) | 2024-02-06 | 2025-08-05 | Madrigal Pharmaceuticals, Inc. | Methods for treating a fatty liver disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2051907C1 (ru) * | 1989-05-22 | 1996-01-10 | Сандос АГ | Способ получения 7-замещенной гептен-6-овой кислоты |
| JP2648897B2 (ja) * | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | ピリミジン誘導体 |
| US5631365A (en) * | 1993-09-21 | 1997-05-20 | Schering Corporation | Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents |
| US6369103B1 (en) * | 1994-01-18 | 2002-04-09 | Bristol-Myers Squibb Company | Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor |
| GB0001621D0 (en) * | 2000-01-26 | 2000-03-15 | Astrazeneca Ab | Pharmaceutical compositions |
| ATE367802T1 (de) * | 2000-09-20 | 2007-08-15 | Jagotec Ag | Verfahren zur sprühtrocknung von zusammensetzungen enthaltend fenofibrat |
-
2000
- 2000-11-22 GB GBGB0028429.9A patent/GB0028429D0/en not_active Ceased
-
2001
- 2001-11-16 AU AU2002214165A patent/AU2002214165B9/en not_active Revoked
- 2001-11-16 MX MXPA03004336A patent/MXPA03004336A/es unknown
- 2001-11-16 KR KR1020037006791A patent/KR100815042B1/ko not_active Ceased
- 2001-11-16 UA UA2003054394A patent/UA75614C2/uk unknown
- 2001-11-16 SK SK621-2003A patent/SK6212003A3/sk not_active Application Discontinuation
- 2001-11-16 HU HU0301380A patent/HUP0301380A3/hu not_active Application Discontinuation
- 2001-11-16 DE DE60133921T patent/DE60133921D1/de not_active Expired - Lifetime
- 2001-11-16 DK DK01982623T patent/DK1339409T3/da active
- 2001-11-16 AU AU1416502A patent/AU1416502A/xx active Pending
- 2001-11-16 CA CA002429263A patent/CA2429263C/en not_active Expired - Fee Related
- 2001-11-16 PL PL01365386A patent/PL365386A1/xx not_active Application Discontinuation
- 2001-11-16 ES ES01982623T patent/ES2305118T3/es not_active Expired - Lifetime
- 2001-11-16 CZ CZ20031406A patent/CZ301583B6/cs not_active IP Right Cessation
- 2001-11-16 SI SI200130839T patent/SI1339409T1/sl unknown
- 2001-11-16 BR BR0115511-3A patent/BR0115511A/pt not_active Application Discontinuation
- 2001-11-16 WO PCT/GB2001/005041 patent/WO2002041895A1/en not_active Ceased
- 2001-11-16 RU RU2003114300/15A patent/RU2294744C2/ru not_active IP Right Cessation
- 2001-11-16 AT AT01982623T patent/ATE394103T1/de active
- 2001-11-16 US US10/432,402 patent/US6858618B2/en not_active Expired - Lifetime
- 2001-11-16 JP JP2002544073A patent/JP5062940B2/ja not_active Expired - Lifetime
- 2001-11-16 IL IL15591901A patent/IL155919A0/xx unknown
- 2001-11-16 CN CNB018221599A patent/CN1268339C/zh not_active Expired - Lifetime
- 2001-11-16 EE EEP200300239A patent/EE05507B1/xx not_active IP Right Cessation
- 2001-11-16 EP EP01982623A patent/EP1339409B1/en not_active Revoked
- 2001-11-16 PT PT01982623T patent/PT1339409E/pt unknown
- 2001-11-16 NZ NZ525754A patent/NZ525754A/en not_active IP Right Cessation
- 2001-11-20 MY MYPI20015303A patent/MY134902A/en unknown
- 2001-11-21 TW TW090128858A patent/TWI238720B/zh not_active IP Right Cessation
- 2001-11-22 AR ARP010105452A patent/AR031766A1/es unknown
-
2003
- 2003-05-12 ZA ZA200303636A patent/ZA200303636B/en unknown
- 2003-05-13 BG BG107811A patent/BG66009B1/bg unknown
- 2003-05-14 IL IL155919A patent/IL155919A/en unknown
- 2003-05-19 IS IS6819A patent/IS6819A/is unknown
- 2003-05-21 NO NO20032292A patent/NO326245B1/no not_active IP Right Cessation
-
2008
- 2008-07-07 CY CY20081100703T patent/CY1110428T1/el unknown
-
2009
- 2009-11-09 JP JP2009255813A patent/JP2010031047A/ja active Pending
Also Published As
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| UEP | Publication of translation of european patent specification |
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